Clinical Trials on Laryngeal Disease

Total 379363 results

University Hospital Ostrava

Recruiting

Benefit of Enhanced Contact Endoscopy in Pre-histological Diagnosis of Laryngeal and Hypopharyngeal Mucosal Lesions

Laryngeal Disease | Laryngeal Lesions | Hypopharyngeal Lesions | Suspected Laryngeal Cancer | Suspected Hypopharyngeal Cancer | Proven Laryngeal Cancer | Proven Hypopharyngeal Cancer

Czechia
University of Alabama at Birmingham

Completed

Resistance Training and Physical Functioning in Head and Neck Cancer Patients

Head and Neck Cancer | Laryngeal Cancer | Pharyngeal Cancer

United States
University of Alabama at Birmingham
American Institute for Cancer Research

Completed

Resistance Training During Radiation Therapy for Pharyngeal or Laryngeal Cancer

Head and Neck Cancer | Laryngeal Cancer | Pharyngeal Cancer

United States
Fudan University

Recruiting

Induction Chemotherapy and Toripalimab Followed by Radiotherapy in Unresectable Laryngeal/Hypopharyngeal Carcinoma

Laryngeal Cancer | Hypopharyngeal Cancer

China
Lumenis Be Ltd.

Completed

ENT FiberLase CO2 Study

Laryngeal Diseases | Pharyngeal Diseases

Belgium, Italy
National Taiwan University Hospital

Unknown

The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma

Laryngeal Cancer | Hypopharyngeal Cancer

Taiwan
Shanghai Yunying Medical Technology
Eye & ENT Hospital of Fudan University

Recruiting

A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer

Head and Neck Cancer | Laryngeal Cancer | Otorhinolaryngologic Neoplasms | Esophageal Cancer | Ear Cancer | Nose Cancer | Pharyngeal Cancer

China
National Institute on Deafness and Other Communication...

Terminated

Patient Evaluation for Head and Neck Surgery Branch Studies

Head and Neck Neoplasms | Carcinoma, Squamous Cell | Laryngeal Cancer | Oral Cancer | Pharyngeal Cancer

United States
Southern Medical University, China

Unknown

Study of Biomarker From Blood and Tissue of Head and Neck Carcinoma

Pharyngeal Neoplasms | Laryngeal Neoplasms
King Faisal Specialist Hospital & Research Center

Completed

Organ Preservation: Weekly Carboplatin & Taxol w/Concurrent RT for Locally Advanced Laryngeal & Hypopharyngeal CA

Hypopharyngeal Neoplasms | Laryngeal Neoplasms

Saudi Arabia
University of Zurich

Completed

A Phase II Study In Patients With Advanced Head And Neck Cancer Of Standard Chemoradiation And Add-On Cetuximab

Laryngeal Cancer | Hypopharyngeal Cancer | Oropharyngeal Cancer

Switzerland
Insel Gruppe AG, University Hospital Bern

Recruiting

The Voice as a Tool to Detect Recurrence of Laryngeal and Hypopharyngeal Cancer (VoiceDetect)

Laryngeal Cancer | Hypopharyngeal Cancer

Switzerland
Wake Forest University Health Sciences

Terminated

Effects of Swallowing Exercises on Patients Undergoing Radiation Treatment for Head and Neck Cancer

Head and Neck Cancer | Stage I Laryngeal Cancer | Stage II Laryngeal Cancer | Stage I Hypopharyngeal Cancer | Stage I Oropharyngeal Cancer | Stage II Hypopharyngeal Cancer | Stage II Oropharyngeal Cancer | Stage III Hypopharyngeal Cancer | Stage III Laryngeal Cancer | Stage III Oropharyngeal Cancer | Stage... and other conditions

United States
National Cancer Institute (NCI)

Completed

Radiation Therapy and Bortezomib and Cetuximab With or Without Cisplatin to Treat Head and Neck Cancer

Head and Neck Cancer | Laryngeal Cancer | Oral Cancer | Carcinoma, Squamous | Pharyngeal Cancer

United States
Centre Hospitalier de Valence

Completed

Evaluation of the French Translation of Swallowing (SOAL-VF) Patient Reported Outcomes (PRO) After Total PharyngoLaryngectomy (SOAL-VF)

Larynx Cancer | Swallowing Disorder | Pharyngeal Cancer

France
National Cancer Institute (NCI)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Biospecimen Procurement for Head and Neck Disorders

Head and Neck Neoplasms | Hearing Disorder | Laryngeal Disease | Oral Mucosal Disease | Pharyngeal Neoplasm

United States
National Taiwan University Hospital

Unknown

The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma

Laryngeal Cancer | Hypopharyngeal Cancer | Metastasis

Taiwan
National Taiwan University Hospital

Unknown

The Role of Lymphangiogenesis in Head and Neck Cancer Metastasis

Laryngeal Cancer | Hypopharyngeal Cancer | Oral Cancer

Taiwan
Azienda USL 4 Prato
Università degli Studi di Brescia

Terminated

Cetuximab Plus Radiotherapy Versus Cisplatin Plus Radiotherapy in Locally Advanced Head and Neck Cancer (CTXMAB+RT)

Head and Neck Neoplasms | Pharyngeal Neoplasms | Mouth Neoplasms | Laryngeal Neoplasms

Italy
Stanford University

Terminated

Assessing the da Vinci® Robotic Surgical System for Surgery of the Upper Aerodigestive Tract

Hypopharyngeal Neoplasms | Laryngeal Neoplasms | Head and Neck Cancers

United States
University of Iowa
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

F-18 Fluorothymidine PET Imaging for Early Evaluation of Response to Therapy in Head & Neck Cancer Patients

Head and Neck Neoplasms | Mouth Neoplasms | Oropharyngeal Neoplasms | Laryngeal Neoplasms

United States
University of Erlangen-Nürnberg Medical School
University Hospital Erlangen; University Hospital Regensburg; University Hospital...

Recruiting

Immune Biomarker Study for Head and Neck Cancer (ImmunBio-KHT)

Head and Neck Cancer | Laryngeal Cancer | Hypopharyngeal Cancer | Oropharyngeal Cancer | Oral Cavity Cancer

Germany
Fudan University
Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Ninth People's Hospital... and other collaborators

Recruiting

Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer

Hypopharyngeal Cancer | Larynx Cancer

China
Mahesh Kudrimoti

Completed

Nicotine Levels With Response Rates to Radiation Alone or With Chemo In Head & Neck Cancer

Oropharyngeal Cancer | Oral Cavity Cancer | Larynx Cancer | Pharyngeal Cancer | Lip Cancer

United States
Michael Seltz Kristensen

Completed

Comparison Between a Standard Tube and the Ultra-thin Tritube for Intubation of the Trachea and for Maintaining Access to the Trachea After Anaesthesia, in Patients With an Expected Difficult Direct Laryngoscopy (Tritube)

Oral Neoplasm | Pharynx Cancer | Larynx Cancer

Denmark
University Hospital, Strasbourg, France
OseoAnvar; Réseau National des Technologies de Santé

Unknown

Voice Prosthesis Made in Porous Titanium After Total Laryngectomy or Pharyngolaryngectomy

Carcinoma | Pharyngeal Neoplasms | Laryngeal Neoplasms

France
Pharmacyclics LLC.

Terminated

Motexafin Gadolinium With Chemotherapy and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer

Head and Neck Cancer | Oropharynx Cancer | Larynx Cancer | Hypopharynx Cancer

United States
Guangdong Provincial People's Hospital

Recruiting

Using the Subglottic Pressure to Predict the Dysphagia After Partial Laryngectomy (SPPDPL)

Laryngeal Cancer | Dysphagia

China
University Medical Center Groningen

Recruiting

Immunological Function After Radiation With Either Proton or Photon Therapy (PRO-IMMUNO)

Head and Neck Cancer | Oropharynx Cancer | Larynx Cancer | HNSCC | Hypopharynx Cancer

Netherlands
MiMedx Group, Inc.

Terminated

Use of Human Dehydrated Amnion Chorion Allograft in Laryngectomy/Pharyngectomy

Pharynx Cancer | Larynx Cancer | Pharyngocutaneous Fistula

United States
Hospices Civils de Lyon

Completed

Laryngeal Disorders After Childhood Cardiac Surgery (RECUP-TML)

Surgery--Complications | Swallowing Disorder | Voice Disorders in Children | Laryngeal Injury

France
University of Washington
Takeda Pharmaceuticals North America, Inc.

Withdrawn

Evaluating Treatment Response in Laryngo-Pharyngeal Reflux

Laryngo-pharyngeal Reflux

United States
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors

Oropharynx Cancer | Oral Cavity Cancer | Larynx Cancer | Hypopharynx Cancer

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in a High Risk Population

Oral Cavity Cancer | Oesophageal Cancer | Pharynx Cancer | Larynx Cancer

France
Sanford Health
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab in Combination With CRT for LA-SCCHN

Head and Neck Cancer | Laryngeal Cancer | Oropharynx Cancer | Oral Cavity Cancer | Larynx Cancer | Squamous Cell Carcinoma | Hypopharynx Cancer

United States
Thompson Cancer Survival Center

Recruiting

Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis

Laryngeal Cancer | Esophageal Cancer | Oropharynx Cancer | Oral Cavity Cancer | Mediastinal Cancer | Head and Neck Cancers - Tonsils | Chest Wall Tumor | Radiation Mucositis

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Pharmacogenetic Response to Chemotherapy Induction for ORL Cancers (APPROCHE ORL)

Carcinoma, Squamous Cell | Mouth Neoplasms | Oropharyngeal Neoplasms | Hypopharyngeal Neoplasms | Laryngeal Neoplasms

France
University Hospital, Strasbourg, France

Completed

The Objective is to Respond to Patients' Needs in the Field of Larynx Replacement

Dysphagia | Swallowing Disorders | Laryngeal Neoplasms

France
Hospices Civils de Lyon

Completed

Interest of MRI in Preoperative Staging for the Laryngeal and Hypopharyngeal Cancer (Larynx MRI)

Hypopharyngeal Carcinoma | Laryngeal Carcinoma

France
Johnny Kao

Completed

Erlotinib, Celecoxib and Reirradiation for Recurrent Head and Neck Cancer

Paranasal Sinus Neoplasms | Cancer of the Head | Cancer of the Neck | Cancer of the Pharynx | Cancer of the Larynx

United States
Johnny Kao

Completed

Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer

Head and Neck Cancer | Nose Neoplasms | Paranasal Sinus Neoplasms | Cancer of the Pharynx | Cancer of the Larynx | Cancer of the Oral Cavity

United States
University of Chicago

Completed

Docetaxel Based Chemotherapy Plus or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE) (DeCIDE)

Paranasal Sinus Neoplasms | Cancer of the Pharynx | Cancer of the Larynx | Cancer of the Nasal Cavity | Cancer of the Oral Cavity

United States, Spain, France, Croatia, Russian Federation
University Hospital Freiburg
Charite University, Berlin, Germany; Icahn School of Medicine at Mount Sinai; Ohio State University and other collaborators

Recruiting

Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy (SENIOR)

Oropharynx Cancer | Oral Cavity Cancer | Larynx Cancer | HNSCC | Hypopharynx Cancer

United States, Cyprus, Germany, Switzerland
Thomas Jefferson University

Completed

Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment

Head and Neck Carcinoma | Lung Carcinoma | Oral Cavity Carcinoma | Paranasal Sinus Carcinoma | Stage III Laryngeal Cancer AJCC v8 | Stage IV Laryngeal Cancer AJCC v8 | Hypopharyngeal Carcinoma | Laryngeal Carcinoma | Stage IVA Laryngeal Cancer AJCC v8 | Stage IVB Laryngeal Cancer AJCC v8 | Stage IVC Laryngeal... and other conditions

United States
University Hospital, Rouen

Completed

Swallowing Disorders After Prolonged Mechanical Ventilation (Deglutube)

Larynx Disease

France
Oregon Health and Science University

Completed

Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft

Quality of Life | Dysphagia | Aspiration

United States
Washington University School of Medicine

Withdrawn

Confocal Laser Microlaryngoscopy (CLMx)

Laryngeal Neoplasm | Laryngeal Dysplasia
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Very Intense Radiotherapy-Chemotherapy Regimen in Advanced HNSCC

Oral Cancer | Oropharynx Cancer | Larynx Cancer | Hypopharynx Cancer

France
Groupe Oncologie Radiotherapie Tete et Cou

Completed

Accelerated Radiotherapy and Concomitant Chemo-radiotherapy in HNSCC

Oral Cancer | Oropharynx Cancer | Larynx Cancer | Hypopharynx Cancer

France
Centre Hospitalier Universitaire de Nīmes

Completed

Surgical Treatment of Early Stage Glotto-supraglottic Laryngeal Cancer Via Transoral Resection With Robotic Assistance

Laryngeal Neoplasms

France

Clinical Trials on Laryngeal Disease

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