Clinical Trials on Left Ventricle Hypertrophied in Czechia

Total 38 results

University Hospital, Motol

Completed

Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

Czechia
University Hospital Ostrava

Active, not recruiting

The Use of Blood Biochemical Markers for Diagnostics of Heart Muscle Diseases

Heart Failure | Left Ventricular Hypertrophy | Heart Dilation

Czechia
Charles University, Czech Republic
Anthropology and Human Genetics; Otorhinolaryngology, 2nd Faculty of Medicine; Department of Newborns with Intensive Care Unit

Unknown

Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty

Cleft Lip and Palate | Cleft Palate | Cleft Lip | Cleft Lip, Bilateral

Czechia
University Hospital Ostrava
VSB - Technical University of Ostrava

Completed

Nanoparticles in Nasal Mucosa

Chronic Polypous Rhinosinusitis | Chronic Hypertrophic Rhinosinusitis

Czechia
Institute for Clinical and Experimental Medicine

Recruiting

Landiolol for Rate Control in Decompensated Heart Failure Due to Atrial Fibrillation (LARISA)

Atrial Fibrillation | Acute Heart Failure | Left Ventricular Dysfunction | Atrial Fibrillation Rapid

Czechia
Berlin Heals GmbH

Recruiting

Performance and Safety of the Cardiac Microcurrent Therapy System (C-MIC-II)

Systolic Left Ventricular Dysfunction

Switzerland, Croatia, Germany, Spain, Serbia, Bosnia and Herzegovina, Bulgaria, Greece, North Macedonia, Poland, Czechia
Institute for Clinical and Experimental Medicine

Recruiting

DOT HeartMate 3 Study

LVAD (Left Ventricular Assist Device) Thrombosis

Czechia
Charles University, Czech Republic
Brno University Hospital; General Teaching Hospital, Prague

Recruiting

The Usefulness of Biatrial 3D Printing to Plan Transseptal Puncture for the Left Atrial Appendage Closure

Atrial Fibrillation | Left Atrial Appendage Closure

Czechia
Charles University, Czech Republic
AstraZeneca

Unknown

CHANCE - Candesartan in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

Czech Republic
Brno University Hospital
Masaryk University; Brno University of Technology

Recruiting

Use of Computer Aided Design and 3D Printing for Anesthesiology Management in a Pediatric Patient With Cleft Facial Defect (3D obturator)

Cleft Lip and Palate

Czechia
Abbott Medical Devices
Thoratec Europe Ltd

Completed

Study of Reduced Anti-coagulation/Anti-platelet Therapy in Patients With the HeartMate II Left Ventricular Assist System (LVAS) (TRACE) (TRACE)

Anticoagulation | Left Ventricular Assist Device

United States, Austria, France, Germany, Czechia
Charles University, Czech Republic
Eli Lilly and Company

Completed

Glucagon-like Peptide 1 Agonist Exenatide for Improved Glucose Control and Cardiac Function in Patients With Aortocoronary Bypass (Executive)

Coronary Artery Disease | Decreased Left Ventricular Function

Czech Republic
Brno University Hospital
Masaryk University; Brno University of Technology

Recruiting

Use of Computer Aided Design and 3D Printing for Anesthesiology Management in a Pediatric Patient With Cleft Facial Defect (3D Obturator) - Pilot Trial (Pilobtur)

Cleft Lip and Palate

Czechia
Oslo University Hospital
South-Eastern Norway Regional Health Authority

Unknown

Global Strain and Mechanical Dispersion May Predict Death and Ventricular Arrhythmias Better Than Ejection Fraction

Left Ventricular Function Systolic Dysfunction

Norway, Czechia
Abbott Medical Devices

Completed

HeartMate 3 CE Mark Study Long Term Follow-up (HM3 CE LTFU)

Advanced Refractory Left Ventricular Heart Failure

Germany, Canada, Austria, Czechia, Kazakhstan, Australia
Abbott Medical Devices
Thoratec Corporation; KCRI; Center for Life Sciences; Emergo

Completed

HeartMate 3™ CE Mark Clinical Investigation Plan (HM3 CE Mark)

Advanced Refractory Left Ventricular Heart Failure

Germany, Australia, Austria, Canada, Czechia, Kazakhstan
Bristol-Myers Squibb

Active, not recruiting

A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM

Hypertrophic Cardiomyopathy | Non-obstructive Hypertrophic Cardiomyopathy | Obstructive Hypertrophic Cardiomyopathy

Denmark, United States, Belgium, Czechia, France, Germany, Israel, Italy, Netherlands, Poland, Portugal, Spain, United Kingdom
Brno University Hospital
Masaryk University

Active, not recruiting

Perioperative Analgesia in Neonates Who Underwent Primary Cleft Lip Repair Surgery

Perioperative Analgesia in Neonates

Czechia
Cytokinetics

Enrolling by invitation

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM (FOREST-HCM)

Symptomatic Hypertrophic Cardiomyopathy (HCM)

United States, France, Israel, Spain, United Kingdom, Italy, Portugal, Poland, Hungary, Denmark, Netherlands, Germany, Czechia
Abbott Medical Devices

Completed

AMPLATZER Cardiac Plug (ACP) Registry-Long Term Follow-up Protocol (ACPR)

Stroke | Atrial Fibrillation | Left Atrial Appendage

Ireland, Spain, United Kingdom, Germany, Czechia
Abbott Medical Devices

Completed

Substrate Modification in Stable Ventricular Tachycardia in Addition to Implantable Cardioverter Defibrillator (ICD) Therapy (VTACH)

Coronary Artery Disease | Ventricular Tachycardia | Left Ventricular Dysfunction

Germany, Switzerland, Czechia, Denmark
MyoKardia, Inc.

Completed

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy (EXPLORER-HCM)

Obstructive Hypertrophic Cardiomyopathy

United States, France, Germany, Czechia, Spain, Belgium, Denmark, Portugal, Netherlands, Israel, Poland, United Kingdom, Italy
Actelion

Completed

Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction (MELODY-1)

Pulmonary Hypertension

United States, Austria, Belgium, Canada, Czechia, France, Germany, Israel, Italy, Spain, Switzerland
Cytokinetics
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Completed

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM (SEQUOIA-HCM) (SEQUOIA-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, France, Spain, Portugal, Germany, China, United Kingdom, Israel, Netherlands, Denmark, Czechia, Hungary, Italy, Poland
BioVentrix

Active, not recruiting

BioVentrix Revivent TC™ System Clinical Study

Ventricular Dysfunction, Left

United States, United Kingdom, Czechia, Greece
Medtronic Cardiac Rhythm and Heart Failure

Completed

REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)

Heart Failure

United States, France, Spain, Germany, Denmark, Canada, Czech Republic, Belgium, Hungary, Italy, Ireland, Sweden, United Kingdom, Austria, Norway
Cytokinetics

Completed

COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF)

Chronic Heart Failure | Pharmacokinetics | Left Ventricular Systolic Dysfunction | Left Ventricular Ejection Fraction | Modified Release Oral Formulation | History of Chronic Heart Failure | Echocardiogram

United States, Canada, Italy, Netherlands, United Kingdom, Belgium, Czechia, Australia, Hungary, Poland, Bulgaria, Lithuania, Germany
Maastricht University
Medtronic; ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

LVSP vs RVP in Patients With AV Conduction Disorders (LEAP)

Atrioventricular Block | Pacing-Induced Cardiomyopathy | Cardiac Pacing | Conduction System Pacing | Left Ventricular Septal Pacing

Spain, Netherlands, Belgium, Czechia, Italy, Switzerland, Poland
Cytokinetics

Completed

Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)

Heart Failure

United States, Canada, Germany, Italy, Netherlands, Belgium, France, Czechia, Australia, Russian Federation, Hungary, Poland, Bulgaria, Slovakia, United Kingdom, Finland, Greece, Lithuania, Norway
Bayer

Terminated

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Diastolic Dysfunction (DILATE)

Hypertension, Pulmonary | Ventricular Dysfunction, Left

Austria, Germany, Czech Republic
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy (MEMENTO)

Cardiomyopathy, Hypertrophic

United States, Argentina, Australia, Belgium, Canada, Czechia, Hungary, Poland, Switzerland, France, Austria, Finland, Germany, Greece, Italy, Spain, United Kingdom
Bristol-Myers Squibb

Active, not recruiting

A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy (ODYSSEY-HCM)

Cardiomyopathy, Hypertrophic

Spain, Austria, Belgium, Brazil, Canada, Denmark, France, Germany, Hungary, Israel, Japan, Netherlands, Norway, Poland, Portugal, United Kingdom, United States, Australia, China, Czechia, India, Italy, Korea, Republic of
AbbVie (prior sponsor, Abbott)
Massachusetts General Hospital

Completed

The PRIMO Study: Paricalcitol Capsules Benefits Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease Stage 3/4 (PRIMO)

Chronic Kidney Disease | Left Ventricular Hypertrophy

United States, Australia, Czech Republic, Germany, Italy, Poland, Puerto Rico, Romania, Russian Federation, Spain, Taiwan, United Kingdom
Cardior Pharmaceuticals GmbH

Active, not recruiting

Study to Assess Efficacy and Safety of CDR132L in Patients With Reduced Left Ventricular Ejection Fraction After Myocardial Infarction (HF-REVERT)

Myocardial Infarction, Acute | Heart Failure, Left Sided

Netherlands, Spain, Hungary, Germany, United Kingdom, Czechia, Poland, Greece
Bayer

Active, not recruiting

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction (LEPHT)

Hypertension, Pulmonary | Ventricular Dysfunction, Left

Belgium, France, China, Spain, Japan, United States, Singapore, Canada, Switzerland, Austria, Denmark, Germany, Italy, Australia, Czechia, Netherlands, Poland, United Kingdom
Abbott
Massachusetts General Hospital; Harvard University

Terminated

The PRIMO II Study: Paricalcitol Injection Benefits in Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease (CKD) Stage 5 (PRIMO II)

Hypertrophy, Left Ventricular | Chronic Kidney Disease (CKD) Stage 5

Italy, United States, Taiwan, Poland, United Kingdom, Greece, Germany, Russian Federation, Spain, Australia, Czech Republic, Puerto Rico, Romania
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma, Childhood and other conditions

United States, Italy, Japan, Germany, Spain, France, Canada, Australia, Brazil, Israel, Russian Federation, Argentina, United Kingdom, Finland, Belgium, Denmark, Czechia, Sweden, Switzerland, Netherlands
Novartis Pharmaceuticals

Recruiting

Pediatric Long-Term Follow-up and Rollover Study

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Neurofibromatosis Type 1 | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma... and other conditions

United States, Belgium, Spain, Denmark, Germany, Czechia, Italy, Australia, Russian Federation, France, Brazil, Netherlands, Japan, Canada, Finland, Sweden, United Kingdom, Argentina, Israel

Clinical Trials on Left Ventricle Hypertrophied in Czechia

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