Clinical Trials on Lesch Nyhan Syndrome

Total 34127 results

Jordan Collaborating Cardiology Group

Recruiting

Clinical Association Between Obstructive Sleep Apnea, Facial Pigmentation, and Vasovagal Symptoms. (VasOSA)

Smoking | Obstructive Sleep Apnea | Acanthosis Nigricans | Vasovagal Syncope

Jordan
Yale University
National Institute of Mental Health (NIMH); National Institutes of Health (NIH)

Recruiting

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy (ART)

Healthy | HIV Dementia | HIV Associated Neurocognitive Disorder | HIV Encephalitis

United States
University of Arizona
Boehringer Ingelheim

Recruiting

Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF

Obstructive Sleep Apnea | Gastro Esophageal Reflux | Idiopathic Pulmonary Fibrosis

United States
Acceleron Pharma Inc. (a wholly owned subsidiary...

Terminated

Extension Study to Evaluate the Long-Term Effects of ACE-083 in Patients With Facioscapulohumeral Muscular Dystrophy (FSHD) and Charcot-Marie Tooth (CMT) Disease Types 1 and X (CMT1 and CMTX)

Charcot-Marie-Tooth Disease | Facioscapulohumeral Muscular Dystrophy

United States, Spain, Canada
University of Illinois at Chicago
Merck Sharp & Dohme LLC

Active, not recruiting

Zepatier in Patients With Substance Use

Hepatitis C | Hiv | Substance Use Disorders | Coinfection, HIV

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Pilot Study Evaluating Penicillin G and Ceftriaxone as Therapies for Presumed Neurosyphilis in HIV Seropositive Individuals

HIV Infections | Neurosyphilis

United States
University of South Florida
National Cancer Institute (NCI); Children's Oncology Group

Completed

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

Sarcoma | Lymphoma | Kidney Cancer | Leukemia | Neurotoxicity | Peripheral Neuropathy

United States
Universidad Peruana Cayetano Heredia
Merck Sharp & Dohme LLC

Completed

Effect of Raltegravir in Patients With Acute Tropical Spastic Paraparesis - Human T-Lymphotropic Virus 1 Infection

HTLV-I Infections | Tropical Spastic Paraparesis

Peru
Instituto Nacional de Enfermedades Respiratorias
National Council of Science and Technology, Mexico; Fundación Clínica Médica...

Completed

Effect of CPAP on Myocardial Dysfunction in Type 2 Diabetes Mellitus and Obstructive Sleep Apnea Patients

Sleep Apnea, Obstructive | Obesity | Diabetes Mellitus, Type 2 | Continuous Positive Airway Pressure | Echocardiography | Myocardial Dysfunction

Mexico
Pharnext SA

Completed

Phase II, Randomized, Placebo-controlled Trial in Patients With Charcot-marie-tooth Disease Type 1A

Charcot-Marie-Tooth Disease | Hereditary Neuropathy With Liability to Pressure Palsies | Genetic Disorders

France
ANRS, Emerging Infectious Diseases

Unknown

Interaction Between High Dose Rifampicine and Efavirenz in Pulmonary Tuberculosis and HIV Co-infection (RIFAVIRENZ)

HIV | Tuberculosis

Uganda
Washington University School of Medicine

Completed

The Effect of HPV Vaccination on Recurrence Rates in HIV Patients With Condylomata

HIV Infections | HIV Positive | Anal Condylomata | Anal Warts

United States
Papworth Hospital NHS Foundation Trust

Unknown

PFO Closure for Obstructive Sleep Apnoea (PCOSA-1)

Obstructive Sleep Apnea | Patent Foramen Ovale

United Kingdom
University of Arizona

Completed

Peripheral Blood Stem Cell Transplantation (PBSCT)From Haploidentical Related Donors

Hematologic Neoplasms | Multiple Myeloma | Anemia, Aplastic | Hemoglobinuria, Paroxysmal

United States
Masonic Cancer Center, University of Minnesota

Recruiting

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Acute Leukemia | Neurofibromatosis 1 | Hematologic Malignancy | Myelodysplasia | Minimal Residual Disease | Chromosome Abnormality | Monosomy 7 | Remission | Somatic Mutation | Cytogenetic Abnormality | TP53 | Fetal Hemoglobin | Intrachromosomal Amplification of Chromosome... and other conditions

United States
University of Miami

Not yet recruiting

Close Obstructive Sleep Apnea (OSA) Trial

Obstructive Sleep Apnea | Patent Foramen Ovale

United States
Centre Hospitalier de Saint-Denis

Recruiting

The Value of HPV Testing for Cervical Cancer Screening in Women Living With HIV (PAPILLO-VIH) (PAPILLO-VIH)

HIV Seropositivity

France
Olof Skoldenberg
The Swedish Association for Survivors of Accident and Injury

Recruiting

Volar Locking Plate Versus External Fixation for Distal Radius Fracture - a Longterm Follow up (EXTEND)

Osteoarthritis | Tendon Injuries | Surgery | Surgery--Complications | Surgical Site Infection | Radius Fracture Distal | Dislocation | CRPS Type I | Tendon Rupture | Treatment Complication | CRPS Type II

Sweden
Ann & Robert H Lurie Children's Hospital of Chicago
National Heart, Lung, and Blood Institute (NHLBI); University of Miami; Northwestern... and other collaborators

Recruiting

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

Premature Birth | Neurodevelopmental Disorders | Asthma in Children | Sleep-Disordered Breathing

United States
Second Affiliated Hospital, School of Medicine,...
Zhejiang University; The First People's Hospital of Huzhou; First Affiliated... and other collaborators

Recruiting

China Headache Registry Study (CHRS)

Migraine | Fibromyalgia | Headache Disorders, Primary | Headache Disorders, Secondary | Tension-Type Headache | Cluster Headache | Vestibular Migraine | Vertigo, Constant

China
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
Peking University First Hospital

Recruiting

Obstructive Sleep Apnea Influences Efficacy of PD-1-Based Immunotherapy Against Non-Small Cell Lung Cancer

Obstructive Sleep Apnea | Non-small Cell Lung Cancer

China
The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy (SLEEP)

Obstructive Sleep Apnea of Adult | Preeclampsia | Obstetrical Complications

United States
St. Joseph's Hospital and Medical Center, Phoenix

Terminated

Effect of Oral Propranolol on mRNA Expresssion in Symptomatic Cavernous Malformation

Cerebral Cavernous Malformations

United States
The Miriam Hospital
Brown University; Brigham and Women's Hospital; Rhode Island Hospital; Women and...

Active, not recruiting

Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP) (PAP-SAP)

Obesity | Sleep | Obstructive Sleep Apnea | Pregnancy | Preeclampsia

United States
Hospital Universitario de Fuenlabrada
Spanish Association of Surgeons (AEC)

Active, not recruiting

Gastric Bypass With Different Lengths of the Bilipancreatic Limb (BPG-1)

Hypertension | Obesity | Diabetes Mellitus, Type 2 | Dyslipidemias | Sleep Apnea | Laparoscopic-Roux-en-Y Gastric Bypass

Spain
National University Health System, Singapore

Completed

Routine Transcervical Thymectomy in MEN-1 Patients

Thymic Carcinoid | Multiple Endocrine Neoplasia Type 1 (MEN-1)

Singapore
Chinese Pulmonary Vascular Disease Research Group

Completed

The Effects of Obstructive Sleep Apnea and Its Intervention on Coronary Heart Disease

Hypertension | Metabolic Disorder
T. van der Poll
ZonMw: The Netherlands Organisation for Health Research and Development; Prothya...

Terminated

C1-inhibitor in Allergic ASThma Patients (CAST)

Asthma

Netherlands
John Hunter Hospital
Newcastle University; Hunter Medical Research Institute

Completed

The Effect of Haemodialysis in Sleep Apnoea

Sleep | Renal Failure | Sleep Disturbance | End Stage Kidney Disease | Sleep Disorders | Sleep Apnoea

Australia
Mid-Atlantic Epilepsy and Sleep Center, LLC

Unknown

Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea (KGDobesity)

Obesity | Diabetes | Obstructive Sleep Apnea

United States
Assistance Publique - Hôpitaux de Paris

Completed

High Blood Pressure and Sleep Apnea in Diabetic Macular Edema (OMHADIA)

Diabetic Retinopathy

France
Novartis Pharmaceuticals

Completed

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Myelofibrosis | Sickle Cell Disease | Thalassemia | Diamond Blackfan Anemia

United States, Netherlands, Taiwan, Thailand, Italy, Germany, Spain, Canada, Belgium, Greece, Turkey, United Kingdom
OMNI Medical Services, LLC
OMNI Medical Services Inc

Recruiting

Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

Depression | COVID-19 | Epilepsy | Multiple Sclerosis | Glaucoma | Cancer | Covid19 | Chronic Pain | Parkinson Disease | Inflammatory Bowel Diseases | Hepatitis C | Insomnia | HIV/AIDS | Amyotrophic Lateral Sclerosis | Fibromyalgia | Anxiety | Bipolar Disorder | Seizures | Crohn Disease | Traumatic Brain Injury | Ulcerative Colitis | Sickle... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
University of Roma La Sapienza
University of Milan; Azienda Policlinico Umberto I; Pavia IRCCS Mondino di Pavia

Recruiting

Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and Vulvodynia (PSYCHOFIBRO)

Fibromyalgia | Vulvodynia | Chronic Migraine, Headache

Italy
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Psychosocial Situation of Children With Rare Solid Abdominal Tumors and Their Families (PsyRareCare)

Neuroblastoma | Hepatoblastoma | Nephroblastoma

Germany
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Brain Tissue Integrity and Autonomic Function Alterations in Childhood OSA and ADHD, and After Adenotonsillectomy.

Attention-deficit/Hyperactivity Disorder | Autonomic Nervous System Imbalance | Obstructive Sleep Apnea of Child

Taiwan
The University of Queensland

Recruiting

The TELO-SCOPE Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis

Pulmonary Fibrosis | Dyskeratosis Congenita | Telomere Shortening | Telomere Disease

Australia
Christian von Buchwald
Bispebjerg Hospital

Recruiting

NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNP

Asthma | Obstructive Sleep Apnea | Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps | Inflammatory Disease | Airway Disease | Concomitant Disease

Denmark
University of Calgary

Not yet recruiting

Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

Stroke | Sleep Disorder | Sleep Apnea | Blood Pressure | Endothelial Dysfunction | Oxidative Stress | Obstructive Sleep Apnea of Adult | Hypoxia, Brain
Scripps Translational Science Institute
Cue Health

Active, not recruiting

ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals

HIV Infections | Lymphoma | Leukemia | Cancer | Multiple Myeloma | Immunosuppression | Immunodeficiency | Transplant | Graft Versus Host Disease | Age-Related Immunodeficiency

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor

Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor

United States, Canada, Australia, New Zealand, Puerto Rico, Israel, Switzerland
Regeneron Pharmaceuticals

Available

Compassionate Use of Pozelimab

Paroxysmal Nocturnal Hemoglobinuria (PNH) | CD55-deficient Protein-losing Enteropathy (PLE) | CD59 Deficiency
Wuhan Union Hospital, China

Completed

Ventilation Modalities and Acute Ischemic Stroke

Sleep Apnea, Obstructive | Acute Ischemic Stroke

China
Centre Hospitalier Universitaire Saint Pierre

Completed

Pertussis Immunization During Pregnancy & HIV Infection

Pertussis | Pregnancy | HIV-1-infection | Immunization; Infection

Belgium
Murdoch Childrens Research Institute
Royal Children's Hospital

Completed

What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?

Primary Immunodeficiency | Invasive Pneumococcal Disease, Protection Against | Invasive Pneumococcal Disease, Recurrent Isolated, 1 | Invasive Pneumococcal Disease, Recurrent Isolated, 2

Australia, New Zealand
Johns Hopkins University
Fusion Health

Completed

Recruitment Strategies Comparing Different Strategies in Sleep Apnea and Prediabetes

Sleep Disorder | Obstructive Sleep Apnea | Pre Diabetes

United States
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Heart Function in Patients Assessed for Sleep Apnoea

Heart Failure | Obstructive Sleep Apnea | Sleep Disordered Breathing | Heart Failure With Preserved Ejection Fraction | Heart Failure With Normal Ejection Fraction | Central Sleep Apnea

United Kingdom
Diskapi Yildirim Beyazit Education and Research...

Unknown

The Effects of Covid-19 Pandemic on The Patients With Fibromyalgia

Fibromyalgia | Anxiety Depression | Sleep Quality | Covid-19 Fear | Covid-19 Anxiety | Daily Life

Turkey

Clinical Trials on Lesch Nyhan Syndrome

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CROs in Qatar

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