Clinical Trials on Lesions of Lumbosacral Intervertebral Disc

Total 1021 results

University of Ljubljana
Novartis; Izola General Hospital; University Medical Centre Ljubljana; General... and other collaborators

Completed

Artificial Intelligence in Predicting Progression in Multiple Sclerosis Study (AI ProMiS)

Multiple Sclerosis | Multiple Sclerosis Lesion | Multiple Sclerosis Brain Lesion

Slovenia
Home Skinovations Ltd.

Completed

Clinical and Usability Study to Determine Safety and Efficacy of the Clear Device for Acne Treatment

Monitor Acne Lessions Count Reduction as Result of Usinfg the Device

Canada
M.D. Anderson Cancer Center

Completed

Comparison of a Novel 22-gauge Core Biopsy Needle

Malignant Neoplasm of Pancreas | Solid Pancreatic Mass Lesions

United States
Frantz Viral Therapeutics, LLC
University of California, San Francisco; Laser Surgery Care; Amarex CRO; Anal Dysplasia...

Active, not recruiting

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL (anal HSIL HIV-)

HPV Infection | Anal Dysplasia | Anal High Grade Squamous Intraepithelial Lesion | Anal Precancerous Condition | AIN 2/3 | HPV Disease

United States
Kirnan, Jaime

Completed

Osteopathic Evaluation on Patients With Non-specific Back Pain: An Inter-examiner Reliability Study

Non-specific Back Pain | Inter-examiner Reliability | Location and Nature of Restriction or Lesion

Canada
Elixir Medical Corporation
Istituto Clinico Humanitas

Active, not recruiting

DYNAMX Bioadaptor ImplanTation for the trEatment of Complex Coronary Lesions (DYNAMITE)

Coronary Artery Disease | Chronic Total Occlusion of Coronary Artery | Multi Vessel Coronary Artery Disease | Bifurcation of Coronary Artery | Long Lesions Coronary Artery Disease

Italy
Centre Hospitalier Régional d'Orléans

Completed

Papilocare®: Effects on Regression of Histologically Confirmed Cervical Intraepithelial Lesions 1 and Tolerance (PAPILOCARE)

Human Papilloma Virus Infection | Squamous Intraepithelial Lesions of the Cervix | Cervix Lesion

France
Xijing Hospital
Xi'an No.3 Hospital; Xi'an Honghui Hospital; Yuncheng Central Hospital; Xi'an No... and other collaborators

Recruiting

The Role of Extracellular DNA (ecDNA) in the Occurrence and Development of Gastric

Gastric Cancer | Precancerous Lesion of Digestive Tract | Extrachromosomal DNA

China
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Conservative Management of HSIL in Patients With Future Pregnancy Aspiration

Cervical Intraepithelial Neoplasia | Uterine Cervical Dysplasia | Squamous Intraepithelial Lesions of the Cervix

Spain
Radboud University Medical Center

Completed

Testing New Vertical Dimension Of Occlusion Prior To Restorative Treatment Of Tooth Wear

Tooth Wear | Randomized Controlled Trial | Composite Resins | Vertical Dimension of Occlusion

Netherlands
Hasselt University
Revalidatie & MS Centrum Overpelt; National MS Center Melsbroek

Recruiting

Auditory-motor Coupling in Multiple Sclerosis With Cerebellar Lesions

Multiple Sclerosis | Cerebral Lesion

Belgium
Cairo University

Not yet recruiting

Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars

Dental Caries | Tooth Demineralization | Tooth Diseases | Deep Caries | Teeth; Lesion | Dental Diseases | Tooth Decay | Dental Restoration Failure of Marginal Integrity | Caries; Dentin
Tel-Aviv Sourasky Medical Center

Completed

CRE8 in All Comers Patients

Consecutive Subjects Who Are Suitable for a Coronary | Angioplasty of de Novo Lesion(s) in Native Coronary | Arteries Should be Screened for Eligibility. | A Total Number of 200 Patients Fulfilling the Selection | Criteria and Willing to Sign the Informed Consent Should | be Enrolled in the...

Israel
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, San Francisco; University... and other collaborators

Active, not recruiting

Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions (ANCHOR)

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | High-grade Squamous Intraepithelial Lesion

United States, Puerto Rico
Halic University

Completed

The Effect of a Mindfulness-Based Stress Reduction Program in Patients With Multiple Sclerosis

Multiple Sclerosis | Mindfulness | Upper Motor Neuron Lesion

Turkey
Centre Hospitalier Universitaire Dijon

Completed

Impact of Malnutrition on the Healing of Foot Lesions in Diabetic Patients

Patients With Type 1 or 2 Diabetes | Lesion Situated on a Toe or on the Plantar or Dorsal Side of the Foot

France
First Affiliated Hospital of Wenzhou Medical University

Recruiting

Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection

HPV Infection | HPV-Related Cervical Carcinoma | Photodynamic Therapy | Low-Grade Squamous Intraepithelial Lesions

China
Antiva Biosciences

Terminated

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | HSIL, High-Grade Squamous Intraepithelial Lesions | Anus Neoplasm

United States, Australia
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

HIV Infection | Anal Cancer | Anus Neoplasms | Human Papilloma Virus Infection | HSIL, High-Grade Squamous Intraepithelial Lesions

United States, Australia
University Hospital, Strasbourg, France

Unknown

Diagnostic and Prognostic Value of p16INK4a Expression in Low Grade Squamous Intraepithelial Lesions of the Cervix.

Cervical Intraepithelial Neoplasia Grade 1 (CIN 1)

France
Johns Hopkins University
Saluda Medical Pty Ltd

Not yet recruiting

Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity (CLONUS)

Chronic Pain | Spasticity as Sequela of Stroke | Upper Motor Neuron Lesion

United States
General University Hospital, Prague

Recruiting

Regression of Cervical Precancerous Lesions and Associated Risk Factors (RECER)

HPV | CIN2 | CIN3 | Cervix Uteri SIL

Czechia
Occyo GmbH
University Clinic for Ophthalmology and Optometry- Salzburg

Completed

CDL Validation Study

Limbal Stem-cell Deficiency | Cornea Disease | Eyes Dry Chronic | Chronic Conjunctivitis of Both Eyes | Eye Lesion | Eye Disease; Cataract | Eyes Dry Feeling of | Cornea Inflamed | Cornea; Injury, Abrasion | Cornea Infection

Austria
Centre Chirurgical Marie Lannelongue
Centre Hospitalier Universitaire de Nice; University Hospital, Limoges; Hôpital... and other collaborators

Completed

OPtimized Stenting Using Intravascular Ultrasound(IVUS) in Long lEsion: Rationale for Simplified criteriA (OPERA)

Diabetes | Coronary Heart Disease | Chronic Total Occlusion of Coronary Artery | Restenosis | Vascular Lesions

France
University of Nebraska
Bracco Diagnostics, Inc; Philips Medical Systems

Completed

Rapid 10-Minute Liver MRI Protocol in Patients With Suspected Hepatocellular Carcinoma

Hepatitis | Fibrosis of Liver | Underlying Liver Disease | Cirrhosis With Suspicion of Liver Cancer | Lesion on a Prior Ultrasound, CT or Outside MRI

United States
University Medical Centre Ljubljana

Completed

Sensitive Troponin I in Out-of-hospital Cardiac Arrest

Cardiac Arrest | Acute Coronary Lesion | Stable Obstructive Coronary Disease | Non-obstructive Coronary Disease

Slovenia
Peoples University, Bhanpur, Bhopal

Completed

Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans

White Spot Lesion of Tooth | Caries, Dental | Orthodontic Appliance Complication | Long Term Adverse Effects

India
University of Sao Paulo
Santander

Terminated

Ear Acupuncture Effectiveness In Reducing The Signs And Symptoms Of Stress And Anxiety (EAEIRTSOSAA)

Inclusion Criteria: | Voluntary Participation in the Study With Available Time for Submission to the Sessions, Which Occur Over Two Months. | Have a Score of Stress Medium, High or Very High in the LSS Questionnaire, Completion of the STAI and General Form. | Exclusion Criteria: | Pregnant...
Clinica Mediterranea

Completed

The XLIMUS-DES in Very Complex Lesions

Chronic Total Occlusion of Coronary Artery | Coronary Atherosclerosis Due to Calcified Coronary Lesion

Italy
Reveal Pharmaceuticals Inc.
National Cancer Institute (NCI)

Recruiting

Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent

Multiple Sclerosis | Brain Neoplasms | Brain Cancer | Brain Tumor | Neurofibroma | Brain Tumors | Brain Metastases | Brain Tumor, Recurrent | CNS Tumor | Acoustic Neuroma | CNS Cancer | CNS Lymphoma | Brain Neoplasms, Benign | Brain Tumor, Primary | CNS Metastases | CNS Lesion | Multiple Sclerosis Brain Lesion | Brain Neoplasm... and other conditions

United States
University of Zagreb
Croatian Science Foundation

Unknown

Salivary Ap4A, SCCA, TROP2 in Oral Cancer Patients (OCSALTM)

Precancerous Lesions | Oral Cavity Squamous Cell Carcinoma | Saliva Altered
University Hospital Ostrava

Completed

Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous Lesions

Carcinoma in Situ | Hoarseness | Recurrent Respiratory Papillomatosis | Chronic Inflammation of Hypopharynx | Macroscopic Laryngeal Lesions | Histological Confirmation of Dysplasia | Invasive Carcinoma of Larynx | Invasive Carcinoma of Hypo Pharynx

Czech Republic
PapiVax Biotech, Inc.
Parexel

Recruiting

Phase II Study of Treatment for HPV16+ ASC-US, ASC-H and LSIL (PVX-2)

ASC-US | LSIL | ASC-H Atypical Squamous Cells, Cannot Rule Out High-Grade Squamous Intra-Epithelial Lesion

United States
Academisch Ziekenhuis Maastricht
Radboud University Medical Center

Recruiting

Oral Microbioma and Oral Malignant Disease

Oral Cancer | Oral Squamous Cell Carcinoma | Premalignant Lesion

Netherlands
Centre Leon Berard

Terminated

A Clinical and Biological Umbrella Protocol for Smoker or Non-smoker Patients With OPML or HNSCC (UMBRELLA)

Head and Neck Squamous Cell Carcinoma (HNSCC) | Premalignant Lesion

France
Centre Hospitalier Universitaire de Nice

Terminated

Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their Precursors

Vulvar Intraepithelial Neoplasia | Vulvar Mucosa Lesions

France
Viome
New York Medical College

Recruiting

Detection of Oral and Throat Cancers Using OralViome Cancer Testing System

Oral Squamous Cell Carcinoma | Oropharynx Squamous Cell Carcinoma | Premalignant Lesion

United States
Peking Union Medical College Hospital
Shijiazhuang Yiling Pharmaceutical Co. Ltd

Unknown

Aspirin as an add-on Treatment of Refractory Epilepsy in Tuberous Sclerosis Complex

Epilepsy | Tuberous Sclerosis Complex | Aspirin | Cognitive Decline | Skin Lesions

China
University of Washington
National Cancer Institute (NCI)

Completed

Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening

Cervical Carcinoma | Human Papillomavirus Infection | Health Status Unknown | Cervical Intraepithelial Neoplasia Grade 2/3 | Stage 0 Cervical Cancer | Atypical Squamous Cell of Undetermined Significance | Low Grade Cervical Squamous Intraepithelial Neoplasia

United States
Zimmer Biomet

Recruiting

Clinical Outcomes Study of the Nexel Total Elbow

Post-traumatic Arthritis | Degenerative Arthritis | Elbow Joint Destruction | Post-traumatic Lesions | Ankylosed Joints | Advanced Rheumatoid Arthritis | Joint Instability or Loss of Motion | Acute Comminuted Articular Fracture of Elbow Joint Surfaces | Bone Loss Contributing to Elbow Instability | Bilateral...

United States, Australia, Finland, France, Germany, Italy, Netherlands, United Kingdom
UMC Utrecht
Turku University Hospital; University of Bologna; University of Roma La Sapienza and other collaborators

Recruiting

Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases (FURTHER)

Quality of Life | Pain | Neoplasm Metastasis | Bone Cancer | Bone Metastases | Tumor | Bone Neoplasm | Bone Lesion | Cancer Induced Bone Pain

Netherlands, Germany, Finland, Italy
University College, London
University College London Hospitals

Completed

Oral Epithelial Dysplasia Informational Needs Questionnaire (ODIN-Q)

Quality of Life | Precancerous Conditions | Patient Engagement | Patient Participation | Oral Disease | Patient Satisfaction | Health Behavior | Precancerous Lesions | Oral Leukoplakia | Dental Diseases | Oral Lichen Planus | Dysplasia | Patient Preference | Information Seeking Behavior | Oral Epithelial Dysplasia | Oral... and other conditions

United Kingdom
UMC Utrecht
Isala

Completed

Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis (PRE-FURTHER)

Quality of Life | Pain | Neoplasm Metastasis | Bone Cancer | Bone Metastases | Tumor | Radiation Toxicity | Bone Neoplasm | Bone Lesion | Cancer Induced Bone Pain

Netherlands
University of Arizona
National Cancer Institute (NCI)

Completed

Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer

Carcinoma in Situ | Head and Neck Cancer | Hyperplasia | Head and Neck Squamous Cell Carcinoma | HNSCC | Dysplasia | Tobacco-Related Carcinoma | Premalignant Lesion

United States
Targeted Therapy Technologies, LLC

Unknown

Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole

Macular Edema | Epiretinal Membrane | Branch Retinal Vein Occlusion | Radiation Retinopathy | Central Serous Retinopathy With Pit of Optic Disc | Commotio Retinae | Vitritis

United States
Targeted Therapy Technologies, LLC

Recruiting

Phase I Study of Episcleral Celecoxib for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole

Macula Edema | Epiretinal Membrane | Branch Retinal Vein Occlusion | Radiation Retinopathy | Central Serous Retinopathy With Pit of Optic Disc | Commotio Retinae | Vitritis

United States
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia | Cervical Squamous Cell Carcinoma In Situ | Cervical Squamous Intraepithelial Neoplasia 2

United States
Inovio Pharmaceuticals

Completed

VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2

Anal Neoplasm

United States, Canada
Dana-Farber Cancer Institute

Recruiting

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Lung Cancer | Cirrhosis | Barrett Esophagus | Hematologic Malignancy | Non-Alcoholic Fatty Liver Disease | Cancer Risk | Vulvar Intraepithelial Neoplasia | Childhood Cancer Survivors | Lung; Node | Non Alcoholic Steatohepatitis | Osteochondroma | Cancer Predisposition Syndrome | Hereditary Cancer Prediction | Adult... and other conditions

United States
Hospital do Divino Espírito Santo de Ponta Delgada

Recruiting

The PORTuguese Registry of Supera Supported Femoral-Fopliteal Revascularization (SupPORT Registry) (SupPORT regist)

Peripheral Arterial Disease | Popliteal Artery Stenosis | Superficial Femoral Artery Occlusion | Popliteal Artery Occlusion | Lower Limb Ischemia | Superficial Femoral Artery Stenosis | Atherosclerosis of Femoral Artery | Chronic Limb Ischemia | Chronic Limb-Threatening Ischemia | Popliteal Arterial Stenosis and other conditions

Portugal

Clinical Trials on Lesions of Lumbosacral Intervertebral Disc

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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