Clinical Trials on Liver Cirrhosis, Biliary

Total 15304 results

Institute of Liver and Biliary Sciences, India

Unknown

Efficacy and Safety of Early TIPS (Transjugular Intrahepatic Portosystemic Shunts) in the Management of Cirrhosis With Recurrent Ascites.

Liver Cirrhoses

India
Sequana Medical N.V.

Recruiting

International Alfapump Cohort Study (TOPMOST)

Liver Cirrhoses | Malignant Ascites

Germany, Switzerland
GlaxoSmithKline

Recruiting

Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN)

Pruritus

United States, France, Italy, Japan, Spain, United Kingdom, Bulgaria, Germany, Greece, China, Argentina, Belgium, Brazil, Canada, Czechia, Israel, Mexico, Poland, Russian Federation, Switzerland
West China Hospital

Recruiting

Ursodeoxycholic Acid Combined With Low Dose Glucocorticoid in the Treatment of PBC With AIH Features II

Hepatitis, Autoimmune | Primary Biliary Cholangitis

China
GlaxoSmithKline

Completed

Dose Response Study of GSK2330672 for the Treatment of Pruritus in Participants With Primary Biliary Cholangitis

Cholestasis

United States, Australia, France, Spain, Germany, Canada, Japan, United Kingdom, Italy, Poland
Mayo Clinic

Withdrawn

Oral Budesonide in the Treatment of Patients With Primary Biliary Cirrhosis and Overlap Features of Autoimmune Hepatitis (PBC)

Autoimmune Hepatitis | Primary Biliary Cirrhosis
Copenhagen University Hospital, Hvidovre
Aarhus University Hospital; Rigshospitalet, Denmark; University of Copenhagen

Terminated

Statins for Prevention of Disease Progression and Hospitalization in Liver Cirrhosis (STATLiver)

Liver Cirrhoses

Denmark
GlaxoSmithKline

Available

Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)

Pruritus
Northwestern University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Cancer... and other collaborators

Recruiting

Liver Cirrhosis Network Cohort Study (LCN-C)

Cirrhosis | Cirrhosis, Liver | Cirrhosis Due to Hepatitis B | Cirrhosis Due to Hepatitis C | Cirrhosis Early | Cirrhosis Advanced | Cirrhosis Infectious | Cirrhosis Alcoholic | Cirrhosis, Biliary | Cirrhosis Cryptogenic | Cirrhosis Due to Primary Sclerosing Cholangitis

United States
National Institute of Diabetes and Digestive and...
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Cancer... and other collaborators

Recruiting

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States (LCN RESCU)

Cirrhosis | Cirrhosis, Liver | Cirrhosis Due to Hepatitis B | Cirrhosis Due to Hepatitis C | Cirrhosis Early | Cirrhosis Advanced | Cirrhosis Infectious | Cirrhosis Alcoholic | Cirrhosis, Biliary | Cirrhosis Cryptogenic | Cirrhosis Due to Primary Sclerosing Cholangitis

United States
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Cholestatic Pruritus

United States
Tongji Hospital
Shanghai Children's Hospital

Completed

Antibiotics Treatment of Cholangitis Post-Kasai Portoenterostomy

Treatment Compliance | Cholangitis, Secondary Biliary | Antibodies Drug Specific

China
Xiaoli Fan

Recruiting

A Randomised Clinical Trial Assessing the Efficacy and Safety of Mycophenolate Mofetil Versus Azathioprine for Induction of Remission in Treatment Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome

Autoimmune Hepatitis | Primary Biliary Cirrhosis

China
Institute of Liver and Biliary Sciences, India

Completed

N-Acetyl Cysteine in the Prevention of Contrast Induced Nephropathy in Cirrhosis of Liver-NEPHRO Trial

Liver Cirrhoses

India
Escient Pharmaceuticals, Inc

Active, not recruiting

Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis (PACIFIC)

Pruritus

United States, United Kingdom, Belgium, Spain, Israel, France, Canada, Netherlands
Zydus Therapeutics Inc.

Recruiting

Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease

Cirrhosis | Hepatic Impairment | Cholestatic Liver Disease

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Unknown

The Effect of Bezafibrate on Cholestatic Itch (FITCH)

Primary Sclerosing Cholangitis | Primary Biliary Cholangitis | Secondary Sclerosing Cholangitis

Netherlands, Spain
Institute of Liver and Biliary Sciences, India

Unknown

Propofol for Sedation of Postoperative Electively Ventilated Liver Transplant Recipients.

Liver Cirrhoses

India
RenJi Hospital

Completed

Early Identification of Myocardial Impairment in PBC (EARLY-MYO-PBC)

Cardiovascular Abnormalities | Primary Biliary Cholangitis

China
Massachusetts General Hospital
Shriners

Recruiting

Developing Viability Index for Machine Perfused Livers

Liver Cirrhoses

United States
Institute of Liver and Biliary Sciences, India

Unknown

To Study the Efficacy and Safety of TIPS (Trans Intrahepatic Portosystemic Shunt) Versus Self Expanding Metallic Stent (SEMS) in the Management of Refractory Variceal Bleed in Cirrhotics.

Liver Cirrhoses

India
Hvidovre University Hospital

Completed

Hemodynamic Alterations in Liver Cirrhosis Validated by Non-invasive MR Compared to Invasive Assessment

Liver Diseases | Cirrhosis | Portal Hypertension | Liver Cirrhoses

Denmark
Albireo

Completed

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases

United Kingdom
Albireo

Completed

A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases
Gilead Sciences

Terminated

Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis

Primary Sclerosing Cholangitis | Compensated Cirrhosis

United States
Daegu Catholic University Medical Center

Completed

The Effects of the Anhepatic Phase Extended by Temporary Portocaval Shunt on Anesthetic Sensitivity and Cognitive Function

Liver Cirrhoses
Xiaoli Fan

Recruiting

Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome

Cholangitis | Hepatitis, Autoimmune | Cholestasis | Liver Cirrhosis, Biliary

China
Medical College of Wisconsin

Terminated

Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit

Liver Failure | ICU Acquired Weakness | Liver Cirrhoses

United States
National Institute of Diabetes and Digestive and...

Completed

Treatment of Cholestatic Pruritus With Sertraline

Hepatitis C | Pruritus | Liver Cirrhosis, Biliary

United States
West China Hospital

Recruiting

Mycophenolate Mofetil Versus Cyclosporin A in the Treatment of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome Due to Nonresponse to Standard Therapy

Hepatitis, Autoimmune | Immunosuppression | Primary Biliary Cholangitis

China
Postgraduate Institute of Medical Education and...

Recruiting

Cirrhotic Cardiomyopathy Based on Point-of-care Echocardiography, Biomarkers and Histology

Cirrhosis, Liver | Cardiac Disease | Cirrhotic Cardiomyopathy

India
University of California, San Diego
Icahn School of Medicine at Mount Sinai; Bayer Healthcare Pharmaceuticals,...

Recruiting

Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis

Liver Cancer | Liver Carcinoma | Liver Cirrhoses

United States
Qilu Hospital of Shandong University

Enrolling by invitation

Prevalence, Clinical Features and Risk Factors of Cirrhotic Cardiomyopathy Assessed by Two-dimensional Speckle Tracking Imaging

Liver Cirrhosis | Cirrhotic Cardiomyopathy

China
Institute of Liver and Biliary Sciences, India

Unknown

The Spectrum and Profile of COVID-19 Infection and Its Impact on Liver.

Liver Cirrhoses

India
Hvidovre University Hospital

Completed

DOCICAR: Cardiac Dysfunction in Cirrhosis

Cirrhosis | Cirrhotic Cardiomyopathy

Denmark
Duke University

Terminated

BRIDGE Device for Post-operative Pain Control (BRIDGE)

Liver Diseases | Liver Failure | Pain, Postoperative | Liver Diseases, Alcoholic | Liver Cirrhosis, Biliary | Transplant; Failure, Liver

United States
Jonel Trebicka

Completed

Role of SWE-change After TIPS in the Prediction of Prognosis After TIPS (TIPS-SWE)

Portal Hypertension | Liver Cirrhoses
Air Force Military Medical University, China

Unknown

Interventional Devascularization Plus HVPG-Guided Carvedilol Therapy vs TIPS

Liver Cirrhoses | Gastric Varices Bleeding
PT. Prodia Stem Cell Indonesia

Recruiting

Umbilical Cord Mesenchymal Stem Cell for Liver Cirrhosis Patient Caused by Hepatitis B

Liver Cirrhoses

Indonesia
University Hospital, Bordeaux

Completed

Acoustic Radiation Force Impulse Imaging (ARFI) : a New Technique to Assess Liver Elasticity (NARFI)

Liver Cirrhosis | Liver Fibrosis | Cardiac Failure | Viral Hepatitis | Liver Tumour | Biliary Cholestasis.

France
Perspectum

Recruiting

Repeatability and Reproducibility of Multiparametric MRI

Liver Diseases | Cirrhosis | Primary Sclerosing Cholangitis | Autoimmune Hepatitis | Hemochromatosis | Non-Alcoholic Fatty Liver Disease | Non-Alcoholic Steatohepatitis | Primary Biliary Cirrhosis | Viral Hepatitis

Netherlands, United Kingdom
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Metoprolol Succinate in Cardiac Remodeling Related to Cirrhosis (CARE Cirrhosis)

Cirrhosis | Cardiac Remodeling | Cirrhotic Cardiomyopathy

Brazil
University Hospital, Bonn

Recruiting

Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease (PERSEVERE)

Liver Cirrhosis | Acute-On-Chronic Liver Failure | Surgery | Portal Hypertension | Non-Cirrhotic Portal Hypertension

Germany
Air Force Military Medical University, China

Not yet recruiting

HVPG-Guided Therapy vs Carvedilol Plus Endotherapy for the Prevention of Esophageal Variceal Rebleeding in Cirrhotic Patients

Liver Cirrhoses | Esophageal Varices | Variceal Hemorrhage

China
King's College Hospital NHS Trust
King's College London; Cardiff University; Guy's and St Thomas' NHS Foundation... and other collaborators

Recruiting

Beta-blockers for Oesophageal Varices (BOPPP)

Cirrhoses, Liver | Oesophageal Varices

United Kingdom
Vinmec Research Institute of Stem Cell and Gene...

Completed

Autologous BMNC Infusion for Liver Cirrhosis in Children With BA (ABMNCBA)

Biliary Atresia

Vietnam
Mayo Clinic

Active, not recruiting

Extracellular RNA Markers of Liver Disease and Cancer

Liver Diseases | Hepatocellular Carcinoma | Cirrhosis | Biliary Tract Cancer

United States
Kasr El Aini Hospital

Completed

Electrophysiological Evaluation of Motor Dysfunction in Liver Cirrhotic Patients

Peripheral Neuropathy | Liver Cirrhoses

Egypt
University of Edinburgh
NHS Lothian

Completed

Prognostic Biomarkers For Acute Kidney Injury In Liver Cirrhosis

Biomarkers | Acute Kidney Injury | Liver Cirrhoses

United Kingdom
Hvidovre University Hospital

Completed

MRI to Assess the Effect of Terlipressin in Patients With Acute Hepatorenal Syndrome (HRS-AKI)

Liver Diseases | Cirrhosis | Acute Kidney Injury | Portal Hypertension | Liver Cirrhoses | Hepato-Renal Syndrome | Cirrhosis Cardiac

Denmark

Clinical Trials on Liver Cirrhosis, Biliary

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