Clinical Trials on Liver Glutathione in Healthy Human in United Kingdom

Total 1673 results

Astellas Pharma Inc

Completed

Comparing Efficacy and Safety of Tacrolimus With Steroids or Monoclonal Anti-IL2R Antibody in Hepatitis C Virus (HCV) Positive Liver Transplant Patients (CHASE)

Liver Transplantation | Hepatitis C

Italy, France, Germany, Sweden, United Kingdom, Poland, Spain, Czech Republic
University College London Hospitals

Completed

Analysis of the Duration of Combination Therapy That is Necessary for HCV Genotype 1 Eradication

Chronic Hepatitis C, HCV Genotype 1

United Kingdom
University of South Carolina
U.S. Army Medical Research and Development Command

Completed

Dietary Seaweed and Early Breast Cancer: A Randomized Trial

Seaweed Associated Changes in Healthy Subjects

United States
Johns Hopkins Bloomberg School of Public Health
National Heart, Lung, and Blood Institute (NHLBI); Oakland University

Recruiting

Developing a Support Application for Food Pantries (SAFPAS) to Improve Client Access to Healthy Foods & Enhance Emergency Preparedness (SAFPAS)

Improving Healthy Food Access in Food Insecurity Populations in Normal and Emergency Situations

United States
University of California, Santa Barbara
National Eye Institute (NEI)

Recruiting

Probing the Role of Feature Dimension Maps in Visual Cognition: Impact of Salience Level (Expt 1.1)

Attention | Basic Science: Visual Attention in Healthy Participants | Basic Science: Neural Representations of Location

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of ASP2215

Healthy | Hepatic Impairment

United States
GlaxoSmithKline

Recruiting

A Study on the Safety and Immune Response of AS37 Together With Hepatitis B Antigen in Adults Aged 18-45 Years

Hepatitis B

Germany, United Kingdom, Belgium
FUJIFILM Toyama Chemical Co., Ltd.
Celerion

Completed

PK Study of T-817 in Subjects With Hepatic Impairment

Healthy | Hepatic Impairment

United States
MDVI, LLC

Completed

Pharmacokinetics of Favipiravir in Volunteers With Hepatic Impairment

Healthy | Hepatic Impairment

United States
Children's Hospital of Philadelphia
Noble Medical, LLC

Completed

Video to Promote HPV Vaccination

Health Behavior | Human Papillomavirus | Acceptance Processes | Social Acceptance | Vaccine Acceptance

United States
Active Genomes Expressed Diagnostics, Corp
Walter Reed National Military Medical Center; Arizona Clinical Trials

Not yet recruiting

AGED Diagnostics Liver Disease Assessment (AGEDDX)

Healthy | NAFLD | NASH With Fibrosis

United States
Hunter Holmes Mcguire Veteran Affairs Medical Center

Completed

Proton Pump Inhibitors and Dysbiosis in Cirrhosis

Healthy | Cirrhosis

United States
Vanderbilt University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Selenium Supplementation of Patients With Cirrhosis

Liver Cirrhosis | Healthy

United States
Exelixis

Completed

Study to Assess the Pharmacokinetics of Cabozantinib (XL184) in Hepatic Impaired Adult Subjects

Healthy | Hepatic Impairment

United States
University of the West of Scotland
Swansea University

Completed

The Influence of a High Intensity Physical Activity Intervention on a Selection of Health Related Outcomes: An Ecological Approach

To Assess the Impact of the HIT Intervention on Physiological Responses | To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours | To Determine the Associations Between CVD Risk Factors at Baseline in 15 - 18 Year Old Youth

United Kingdom
Pharmasset
Hoffmann-La Roche

Completed

Adaptive Phase I HCV Study With Nucleoside Analogue, in Combination With Interferon and Ribavirin (R7128)

Healthy Volunteers | Hepatitis C Virus

United States, Puerto Rico, New Zealand
Shire

Completed

Study of SSP-004184 (SPD602) in Healthy Adults and Subjects With Impaired Liver Function

Healthy | Hepatic Impairment

United States
Nonin Medical, Inc

Completed

Hypoxia at Multiple Wavelengths of Light

Hypoxia in Healthy Individuals

United States
Reata, a wholly owned subsidiary of Biogen

Completed

Single-Dose, Open-Label Pharmacokinetic Study of Bardoxolone Methyl in Subjects With Mild, Moderate, and Severe Hepatic Impairment and Normal Hepatic Function

Healthy | Hepatic Impairment

United States
Northwestern University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Active, not recruiting

Navigating New Motherhood 2 (NNM2)

Contraception | Breastfeeding | Preventive Care / Anticipatory Guidance | Retention in Care | Postpartum Health

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Contrast-enhanced MRI in Detecting Benign and Malignant Liver Lesions

Hepatocellular Carcinoma | Liver and Intrahepatic Bile Duct Disorder | Metastatic Malignant Neoplasm in the Liver | Primary Malignant Liver Neoplasm

United States
Pfizer

Completed

STUDY OF PF-06882961 IN PARTICIPANTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIREMENT

Healthy Volunteers | Hepatic Impairment

United States
ObsEva SA

Completed

Safety and Pharmacokinetics Study of Linzagolix in Female Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment | Healthy Participants

United States
NewAmsterdam Pharma
Veranex

Recruiting

PK and Safety in Participants Taking Obicetrapib With Moderate Hepatic Impairment Relative to Normal Hepatic Function

Healthy | Hepatic Impairment

United States
Mercy Medical Center

Recruiting

Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis

Hepatitis B | Cirrhosis, Liver | Chronic Liver Disease

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Liver | Metastatic Malignant Neoplasm in the Lung

United States
Lexicon Pharmaceuticals

Completed

PK Study of Sotagliflozin in Subjects With Hepatic Impairment

Healthy | Hepatic Impairment

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate Pharmacokinetics (PK) and Safety of Oral Mobocertinib in Participants With Moderate or Severe Hepatic Impairment (HI) and Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed in People With Liver Dysfunction

Healthy Volunteers | Hepatic Impairment

United States
Pfizer

Completed

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of PF-06651600 in Subjects With Hepatic Impairment and Healthy Volunteers

Hepatic Impairment | Healthy Participants

United States
Presidio Pharmaceuticals, Inc.

Completed

A Phase 1b Study of PPI-461 in Patients With HCV Genotype 1

Chronic Genotype 1 Hepatitis C Virus Infection

United Kingdom, Denmark, United States
Massachusetts General Hospital

Terminated

DAA Treatment in Donor HCV-positive to Recipient HCV-negative Liver Transplant

End Stage Liver Disease | Hepatitis C

United States
Rebiscan, Inc.
BlueGrass Orthopaedics Surgery & Hand Care

Completed

Neuro-ocular Baselines in a Sports Setting (KY)

Wave Form Signals Coming From the Eye in a Healthy Cohort

United States
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

A Pharmacokinetics and Tolerability Study of Fedratinib in Subjects With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
AMAG Pharmaceuticals, Inc.

Completed

Comparing Bioavailability When Preservative-free Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) is Administered as an Intramuscular Manual Injection or as a Subcutaneous Injection Using an Auto-injector in Healthy Post-menopausal Women

Comparing Bioavailability When Makena® is Administered in Healthy Post-menopausal Women

United States
Takeda

Recruiting

A Study of TAK-279 in Adults With or Without Liver Damage

Healthy Volunteers | Hepatic Impairment

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate ASP0367 in Participants With Mild/Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Celgene

Completed

Evaluate the Pharmacokinetics of CC-220 in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared With Healthy Subjects

Healthy Volunteers | Hepatic Impairment

United States
M.D. Anderson Cancer Center

Active, not recruiting

BMS-986156, Ipilimumab, and Nivolumab With or Without Stereotactic Body Radiation Therapy in Treating Patients With Advanced or Metastatic Lung/Chest or Liver Cancers

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Carcinoma in the Liver | Metastatic Carcinoma in the Lung | Metastatic Malignant Neoplasm in the Thoracic Cavity

United States
Bristol-Myers Squibb

Not yet recruiting

A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Mild and Moderate Hepatic Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
University of Virginia
Duke University; Hong Kong Polytechnic University

Recruiting

4D-MRI for Precision Medicine

Lung Cancer | Healthy Volunteers | Liver Cancer

United States
Takeda

Completed

A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

United States, Hungary
Ono Pharma USA Inc
Ono Pharmaceutical Co. Ltd

Completed

An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment

Healthy | Hepatic Impairment

United States
Icahn School of Medicine at Mount Sinai
KineMed

Terminated

Biomarkers of Liver Fibrosis

Hepatitis C

United States
Vaccitech (UK) Limited

Active, not recruiting

First-In-Human Study of ChAdOx1-HBV & MVA-HBV Vaccines (VTP-300) for Chronic HBV

Hepatitis B

Korea, Republic of, Taiwan, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Study of VX-950, Pegasys® With and Without Copegus® in Hepatitis C

Chronic Hepatitis C

Austria, France, Germany, United Kingdom
HepQuant, LLC

Completed

Intra-Individual Reproducibility of the Non-Invasive Assessment of the Portal Circulation (Repro)

Hepatitis C, Chronic | Non-Alcoholic Fatty Liver Disease

United States
Gilead Sciences

Completed

Open Label Study of Pharmacokinetics and Safety of Dose of Adefovir Dipivoxil in Children and Adolescents With HBV

Hepatitis B

Belgium, Germany, Poland, United Kingdom
Altimmune, Inc.

Completed

Phase I Safety and Immunogenicity of FP-02.2 in Chronic Hepatitis B

Hepatitis B

Korea, Republic of, United Kingdom

Clinical Trials on Liver Glutathione in Healthy Human in United Kingdom

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