Clinical Trials on Localized Pancreatic Adenocarcinoma

Total 14887 results

National Health Research Institutes, Taiwan

Recruiting

Peri-operative SLOG for Localized Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma | Pancreas Cancer

Taiwan
Changhai Hospital

Recruiting

Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Advanced Cancer | Pancreatic Ductal Adenocarcinoma

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Binimetinib and Hydroxychloroquine in Treating Patients With KRAS Mutant Metastatic Pancreatic Cancer

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma

United States
Emory University
National Cancer Institute (NCI); Novartis; National Institutes of Health (NIH); EUSA Pharma, Inc...

Completed

Siltuximab and Spartalizumab in Patients With Metastatic Pancreatic Cancer

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma

United States
National Cancer Institute (NCI)

Completed

3-AP and Radiation Therapy in Treating Patients With Stage III Pancreatic Cancer That Cannot Be Removed By Surgery

Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer AJCC v6 and v7

United States
University of Cologne

Recruiting

Clinical Trial to Evaluate Efficacy and Safety of Dupilumab in Localized Scleroderma (DupiMorph)

Localized Scleroderma

Germany
Cairo University

Unknown

Fractional Carbon Dioxide Laser Versus UVA 1 in Treatment of Localized Scleroderma

Localized Scleroderma

Egypt
National Cancer Institute (NCI)

Recruiting

Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial

Malignant Solid Neoplasm | Stage IV Pancreatic Cancer AJCC v8 | Pancreatic Carcinoma | Stage IV Ovarian Cancer AJCC v8 | Ovarian Low Grade Serous Adenocarcinoma

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Neoadjuvant Chemotherapy Followed by Radiation Therapy and Gemcitabine/Sorafenib/Vorinostat in Pancreatic Cancer

Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
AdventHealth

Completed

Trial Comparing EUS-guided Radiofrequency Ablation vs. EUS-guided Celiac Plexus Neurolysis

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreatic Carcinoma Metastatic | Pancreatic Cancer, Adult

United States
University of Nebraska
National Cancer Institute (NCI); Adherex Technologies, Inc.

Completed

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

Pancreatic Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IVA Pancreatic Cancer | Stage IVB Pancreatic Cancer | Stage IIIA Gallbladder Cancer | Stage IIIB Gallbladder Cancer | Stage IVA Gallbladder Cancer | Stage IVB Gallbladder Cancer | Gallbladder Adenocarcinoma and other conditions

United States
Ludwig-Maximilians - University of Munich
Roche Pharma AG

Unknown

Gemcitabine Plus Erlotinib in RASH-positive Patients With Metastatic Pancreatic Cancer (ML22774)

Metastatic Pancreatic Adenocarcinoma

Germany
Foundation for Liver Research

Withdrawn

Pancreatic Enzyme Suppletion in Pancreatic Cancer (EPC)

Adenocarcinoma of the Pancreas | Normal Pancreatic Exocrine Function

Netherlands
National Cancer Institute (NCI)

Completed

Radiotherapy Combined With Oxaliplatin and Fluorouracil Followed By Gemcitabine in Treating Patients With Locally Advanced, Unresectable Pancreatic Cancer

Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer | Stage II Pancreatic Cancer

United States
Blood Transfusion Centre of Slovenia
University Medical Centre Ljubljana

Unknown

Influence of Gemcitabine Treatment on Immunological and Serological Profile in Patients With Pancreatic Cancer (GEMSTHER)

Pancreatic Tubular Adenocarcinoma

Slovenia
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Predicting Effective Therapy in Pancreatic Cancer

Pancreatic Cancer | Pancreatic Adenocarcinoma

United States
Tigenix S.A.U.

Completed

Intralymphatic eASC Administration in Healthy Volunteers

Localized Adverse Reaction to Administration of Drug

Spain
Wake Forest University Health Sciences

Withdrawn

HIPEC as Neoadjuvant Treatment for Resectable Pancreatic Adenocarcinoma

Pancreatic Neoplasms | Pancreatic Adenocarcinoma

United States
Varian Medical Systems

Completed

STOPPER CHINA:With Tandem Microspheres in the Treatment of Localized Hepatocellular Carcinoma

Localized Hepatocellular Carcinoma

China
Sidney Kimmel Comprehensive Cancer Center at Johns...

Recruiting

Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma

Pancreatic Ductal Adenocarcinoma | Oligometastatic Disease

United States
Changhai Hospital
Stemirna Therapeutics

Unknown

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Digestive System Neoplasms

Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Colorectal Adenocarcinoma | Advanced Esophageal Squamous Carcinoma

China
National Cancer Institute (NCI)

Terminated

RO4929097 Before Surgery in Treating Patients With Pancreatic Cancer

Adenocarcinoma of the Pancreas | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Capecitabine, Bevacizumab, and Radiation Therapy Followed By Gemcitabine and Bevacizumab in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery

Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer | Stage II Pancreatic Cancer

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Combination Chemotherapy Plus Radiation Therapy With or Without Tipifarnib in Treating Patients With Locally Advanced Pancreatic Cancer

Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer | Stage II Pancreatic Cancer

United States
Emory University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; National Institutes... and other collaborators

Completed

Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancer

Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Recurrent Colorectal Carcinoma | Colorectal Adenocarcinoma | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVA Pancreatic... and other conditions

United States
Yonsei University

Terminated

Oncologic Impact of Splenectomy-omitting Radical Pancreatectomy in Well-selected Left-sided Pancreatic Cancer

Ductal Adenocarcinoma | Left-sided Pancreatic Cancer

Korea, Republic of
Royal Cornwall Hospitals Trust
Biocartis

Completed

KEBI-Cyto Study - Use of the Biocartis Idylla

Pancreatic Adenocarcinoma | Lung Cancer

United Kingdom
Castle Creek Biosciences, LLC.

Terminated

A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)

Scleroderma, Localized | Morphea | Scleroderma

United States
Chinese PLA General Hospital

Recruiting

Surufatinib Plus Camrelizumab and AS in First Line Treatment of Advanced Metastatic Pancreatic Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Pancreas Cancer | PDAC - Pancreatic Ductal Adenocarcinoma

China
University Hospital, Ghent

Completed

Feasibility of Radiotherapy and Concomitant Gemcitabine and Oxaliplatin in Locally Advanced Pancreatic Cancer and Distal Cholangiocarcinoma

Locally Advanced and Unresectable, But Non-metastatic Pancreatic Adenocarcinoma or Cholangiocarcinoma

Belgium
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University; American...

Terminated

Monitoring Heart Rate Variability for the Early Detection of Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma | Stage I Pancreatic Cancer AJCC v8 | Stage IA Pancreatic Cancer AJCC v8 | Stage IB Pancreatic Cancer AJCC v8

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Recruiting

NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer

Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Stage 0 Pancreatic Cancer AJCC v8 | Stage I Pancreatic Cancer AJCC v8

United States
Thomas Jefferson University

Suspended

A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma

Malignant Solid Neoplasm | Gastric Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Colorectal Adenocarcinoma | Small Intestinal Adenocarcinoma | Clinical Stage III Gastric Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC... and other conditions

United States
University of Rochester

Completed

Pilot Study of Short-Course Preoperative Stereotactic Body Radiation Therapy for Resectable Pancreatic Cancer

Adenocarcinoma | Pancreatic Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

Pancreatic Adenocarcinoma | Unresectable Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7

United States
Roswell Park Cancer Institute
Novartis

Completed

Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer

Advanced Malignant Solid Neoplasm | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | ALK Positive

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

A Phase I/II/Pharmacodynamic Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane to Inhibit Autophagy in Pancreatic Cancer

Metastatic Adenocarcinoma | Advanced Adenocarcinoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Disulfiram and Chemotherapy in Treating Patients With Refractory Solid Tumors or Metastatic Pancreatic Cancer

Refractory Malignant Solid Neoplasm | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma

United States
AIO-Studien-gGmbH
Celgene Corporation; ClinAssess GmbH

Completed

First-line Treatment of Metastatic Pancreatic Cancer With Nab-paclitaxel and Gemcitabine (ALPACA)

Adenocarcinoma of the Pancreas | Metastatic Pancreatic Cancer

Germany
The Affiliated Hospital of Qingdao University

Recruiting

Prognostic Value of Myosteatosis and Creatinine-to-cystatin C Ratio in Patients With Pancreatic Ductal Adenocarcinoma

Pancreatic Ductal Adenocarcinoma | Myosteatosis | Skeletal Muscle Radiodensity | Scr/CysC Ratio

China
University of Nebraska
National Cancer Institute (NCI)

Recruiting

Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer

Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7 | Stage I Pancreatic Cancer AJCC v6 and v7 | Stage IA Pancreatic Cancer AJCC v6 and v7 | Stage IB Pancreatic Cancer AJCC v6 and v7 | Stage II Pancreatic... and other conditions

United States
University Health Network, Toronto
GlaxoSmithKline

Completed

A Study of GSK2256098 and Trametinib in Advanced Pancreatic Cancer

Adenocarcinoma | Pancreatic Cancer

Canada
HistoSonics, Inc.

Not yet recruiting

The HistoSonics Edison™ System for Treatment of Pancreatic Adenocarcinoma Using Histotripsy (GANNON)

Pancreatic Cancer | Pancreas Cancer | Adenocarcinoma of the Pancreas | Tumor of Pancreas

Spain
National Cancer Institute (NCI)

Active, not recruiting

FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer

Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride in Treating Patients With Locally Advanced Pancreatic Cancer

Duct Cell Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
National Cancer Institute (NCI)

Completed

Gemcitabine With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage II Pancreatic Cancer

United States
National Cancer Institute (NCI)

Completed

Flavopiridol Plus Radiation Therapy Followed By Gemcitabine Hydrochloride in Treating Patients With Locally Advanced, Unresectable Pancreatic Cancer

Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage II Pancreatic Cancer

United States
National Cancer Institute (NCI)

Completed

UCN-01 and Gemcitabine in Treating Patients With Unresectable or Metastatic Pancreatic Cancer

Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage II Pancreatic Cancer

United States
Universita di Verona

Recruiting

Dissecting the Pattern of Nodal Spread in Post-neoadjuvant Pancreatoduodenectomy

Pancreatic Adenocarcinoma | Pancreas Cancer

Italy

Clinical Trials on Localized Pancreatic Adenocarcinoma

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