Clinical Trials on Lung Biopsy in Czechia

Total 768 results

Sanofi

Active, not recruiting

Tusamitamab Ravtansine (SAR408701) in Combination With Ramucirumab or Ramucirumab and Pembrolizumab in Pretreated Patients With NSQ NSCLC (CARMEN-LC04) (CARMEN-LC04)

Non-small Cell Lung Cancer Metastatic

Korea, Republic of, United States, Bulgaria, Czechia, Portugal, Spain
Ionis Pharmaceuticals, Inc.

Terminated

A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

Germany, Czechia, Hungary, United Kingdom
AstraZeneca

Active, not recruiting

Study of Durvalumab in Combination With Platinum and Etoposide for the First Line Treatment of Patients With Extensive-stage Small Cell Lung Cancer (LUMINANCE)

Extensive-stage Small Cell Lung Cancer

Canada, Germany, Italy, Czechia, Turkey, Bulgaria
GlaxoSmithKline

Completed

Safety & Immunogenicity of Pneumococcal Vaccine 2189242A in Children Aged 12-23 Months at the Time of First Vaccination

Infections, Streptococcal

Czechia
University Hospital, Motol

Unknown

Impact of Immunonutrition on the Patients With Cystic Fibrosis

Malnutrition | Cystic Fibrosis | Oxidative Stress

Czech Republic
European Organisation for Research and Treatment...

Completed

Paclitaxel in Treating Patients With Lung Cancer

Lung Cancer

Germany, Netherlands, Italy, Belgium, Czech Republic
Boehringer Ingelheim

Recruiting

INCHANGE - Nintedanib for Changes in Cough and Dyspnea in Patients Suffering From Chronic Fibrosing Interstitial Lung Disease With a Progressive Phenotype in Everyday Clinical Practice: a Real-world Evaluation

Lung Diseases, Interstitial

Czechia, Switzerland, Romania, Bulgaria, Poland
Biocad

Recruiting

Efficacy and Safety of BCD-100 (Anti-PD-1) in Combination With Platinum-Based Chemotherapy as First Line Treatment in Patients With Advanced Non-Squamous NSCLC (DOMAJOR)

Non-Squamous Non-Small Cell Neoplasm of Lung

Czechia, Romania, Georgia, Hungary, Russian Federation, Slovakia
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
GlaxoSmithKline

Completed

Prophylactic Antipyretic Treatment in Children Receiving Booster Dose of Pneumococcal Conjugate Vaccine GSK1024850A

Infections, Streptococcal

Czechia
UMC Utrecht
University Hospital, Geneva; Universiteit Antwerpen

Completed

HOspital NEtwork STudy - Preparation for a Randomized Evaluation of Anti-Pneumonia Strategies (HONEST-PREPS)

Hospital-acquired Pneumonia | Ventilator Associated Pneumonia

France, Czechia, Serbia, Croatia, Latvia, Romania, Albania
Flatley Discovery Lab LLC

Completed

A Study to Evaluate Safety, PK and PD of FDL169 in Cystic Fibrosis Subjects

Cystic Fibrosis

United Kingdom, Australia, Germany, Czechia
Boston Scientific Corporation

Completed

Bronchial Thermoplasty Global Registry (BTGR)

Asthma

Spain, Italy, Germany, Netherlands, Australia, Czechia, South Africa, United Kingdom
NovoCure Ltd.

Unknown

Effect of TTFields (150kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-5 Brain Metastases Following Optimal Standard Local Treatment (COMET)

1-5 Brain Metastases From Non-Small Cell Lung Cancer

Poland, Czech Republic, Italy, France, Spain
AstraZeneca

Completed

ZD4054 (Zibotentan) Phase II Non-Small Cell Lung Cancer Study

Lung Cancer | Non Small Cell Lung Cancer

Bulgaria, Romania, Ukraine, France, Czech Republic
AstraZeneca

Completed

Characterisation of Patients With Severe Asthma in Primary and Secondary Care Settings in Europe Reported to be Eligible for Biological Therapy (RECOGNISE)

Severe Asthma

Hungary, Germany, Bulgaria, Czechia, France, Greece, Italy, Netherlands, Poland, Romania, Slovenia, Spain
SOTIO Biotech AG
SOTIO Biotech a.s.

Active, not recruiting

Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Bladder Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Thyroid | Anal Cancer | Merkel Cell Carcinoma | Biliary... and other conditions

United States, France, Spain, Czechia
Laboratoire de la Mer

Unknown

Efficacy of Natural Seawater Based Throat Spray in Acute Sore Throat Relief (FLASH)

Sore Throat

Czechia
Chiesi Farmaceutici S.p.A.

Completed

Study to Evaluate Efficacy/Safety of 4 Doses of CHF5259 Via Dry Powder Inhaler (DPI) in Patients With COPD (GlycoNEXT)

Chronic Obstructive Pulmonary Disease (COPD)

Czechia, Germany, Hungary, Romania
Boehringer Ingelheim

Active, not recruiting

A Study to Evaluate Long-term Safety of Nintedanib in Children and Adolescents With Interstitial Lung Disease (InPedILD®-ON)

Lung Diseases, Interstitial

United States, Spain, United Kingdom, Canada, Finland, Norway, Italy, Argentina, Belgium, Brazil, Czechia, France, Greece, Mexico, Poland, Germany, Portugal
AstraZeneca

Completed

Efficacy and Safety of Two Fixed Dose Combinations of Aclidinium Bromide With Formoterol Fumarate (ALIGHT-COPD)

Chronic Obstructive Pulmonary Disease

Romania, Czech Republic
Bayer

Completed

EXPERT, EXPosurE Registry RiociguaT in Patients With Pulmonary Hypertension (EXPERT)

Hypertension, Pulmonary

Turkey, Austria, Czechia, Russian Federation, Slovakia, Switzerland, Italy, Germany, United Kingdom, France, Belgium, Canada, Colombia, Greece, Luxembourg, Netherlands, Spain, Taiwan, Denmark, Sweden, Argentina, Portugal, Saudi Arabia, Austral... and more
AOP Orphan Pharmaceuticals AG

Enrolling by invitation

A Prospective Non-interventional Observational Study to Observe Long-term Treatment and Outcomes in Pulmonary Arterial Hypertension (PAH) Patients (TripleTRE-NIS)

Pulmonary Arterial Hypertension

France, Spain, Germany, Italy, Hungary, Austria, Czechia, Poland, Romania
Lung Biotechnology PBC

Completed

Dose-response Study of the Safety and Efficacy of Beraprost Sodium Modified Release (BPS-MR) in Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
Stichting European Myeloma Network
Fondazione EMN Italy Onlus

Completed

COVID-19 Infection and Multiple Myeloma (EMN-COVID)

Covid19 | Multiple Myeloma | Corona Virus Infection

Czechia, Netherlands, United Kingdom, Belgium, Germany, Austria, Greece, Italy
GlaxoSmithKline

Completed

Post-marketing Study to Evaluate the Efficacy of Influenza Vaccine

Influenza

Czech Republic
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Safety of Elexacaftor/Tezacaftor/Ivacaftor in Participants With Cystic Fibrosis (CF)

Cystic Fibrosis

Spain, Belgium, Australia, Canada, Czechia
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-770 in Subjects With Moderate Hepatic Impairment and in Matched Healthy Subjects

In Development for Cystic Fibrosis

Czech Republic, Slovakia
Lung Biotechnology PBC

Completed

Extension of BPS-MR-PAH-203 in Pulmonary Arterial Hypertension (PAH) Patients

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
Novartis Pharmaceuticals

Completed

Efficacy of QAX576 in Asthma

Asthma

Germany, United States, Poland, Belgium, Argentina, Russian Federation, Czechia
AOP Orphan Pharmaceuticals AG
GCP-Service International Ltd. & Co. KG; ANOVA CRO s.r.o.; PharmaLex Belgium; Aixial...

Recruiting

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients (TripleTRE)

Pulmonary Arterial Hypertension

Austria, Spain, France, Germany, Italy, Czechia, Hungary, Poland, Portugal, Romania
Novartis Vaccines

Completed

Safety and Immunogenicity of Two Doses of Monovalent Inactivated Influenza Vaccine That is Adjuvanted With MF59C.1 (MF59) and Uses a Surface Antigen From a Potential Pandemic Virus Strain Candidate (H5N1) in Adult and Elderly Subjects Using Four Different Vaccination Schedules

Pre-pandemic Influenza Vaccine

Czech Republic
Novartis Pharmaceuticals

Terminated

PDR001 in Combination With Platinum-doublet Chemotherapy and Other Immunology Agents in PD-L1 Unselected, Metastatic NSCLC Patients

Non-small Cell Lung Cancer

France, Spain, United States, Belgium, Netherlands, Canada, Italy, Singapore, Korea, Republic of, Czechia, Germany, Hong Kong
GlaxoSmithKline

Completed

A Study to Evaluate the Effect of Umeclidinium (UMEC) as Combination Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Netherlands, Greece, Czechia
Galapagos NV

Completed

A Study to Evaluate GLPG2222 in Ivacaftor-treated Subjects With Cystic Fibrosis

Cystic Fibrosis

Ireland, United Kingdom, Belgium, Australia, Czechia, Germany
Sanofi

Active, not recruiting

Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Platinum-based Chemotherapy With or Without Pemetrexed in Patients With NSQ NSCLC (CARMEN-LC05)

Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)

Spain, United States, Brazil, Chile, Czechia, France, Hungary, Israel
Pfizer

Terminated

Safety And Efficacy Study Of Avelumab Plus Chemotherapy With Or Without Other Anti-Cancer Immunotherapy Agents In Patients With Advanced Malignancies

Non-small Cell Lung Cancer | Urothelial Cancer

Spain, Czechia, United States, Australia, United Kingdom, Italy, Canada, Hungary
Charles University, Czech Republic

Completed

Combined RF Surgery of the Tongue Base and Uvulopalatopharyngoplasty (UPPP) for Obstructive Sleep Apnea

Sleep Apnea Syndrome

Czech Republic
RAPT Therapeutics, Inc.

Suspended

Phase 2 Study to Evaluate RPT193 in Adults With Moderate to Severe T2-high Asthma

Asthma

United States, Bulgaria, Czechia, Poland
Novartis Pharmaceuticals

Completed

Study of Efficacy, Safety and Tolerability of CMK389 in Patients With Chronic Pulmonary Sarcoidosis

Pulmonary Sarcoidosis

United States, Germany, Poland, Czechia, Denmark, United Kingdom
Redx Pharma Plc
Simbec Research

Recruiting

Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of RXC007 in Idiopathic Pulmonary Fibrosis

Fibrosis | IPF

Italy, Spain, United States, Belgium, United Kingdom, Austria, Czechia, Poland, Switzerland
Nippon Kayaku Co., Ltd.

Completed

Phase II Study on Gusperimus in Patients With Refractory Wegener's Granulomatosis

Wegener's Granulomatosis

United Kingdom, Germany, Sweden, Czech Republic, Denmark, Netherlands
Novartis Pharmaceuticals

Completed

Study of Efficacy of Fevipiprant in Patients With Nasal Polyposis and Asthma (THUNDER)

Nasal Polyps

Germany, Belgium, Italy, Argentina, Canada, Netherlands, Czechia, Poland, United States
University Hospital Ostrava

Completed

Suitable Method for Routine Diagnostics of EER in Children With Otitis Media With Effusion

Otitis Media With Effusion

Czech Republic
Novartis Pharmaceuticals

Active, not recruiting

To Assess the Efficacy of the Investigational Products Compared to Placebo in Participants With IPF

Idiopathic Pulmonary Fibrosis

Poland, United States, Germany, Australia, Czechia, Argentina, Netherlands
Menarini International Operations Luxembourg SA

Completed

Efficacy of Co-administration of Bilastine and Montelukast in Patients With SARC and Asthma (SKY)

Asthma | Seasonal Allergic Rhinoconjunctivitis

Poland, Romania, Germany, Italy, Czechia, Latvia, Croatia, Slovakia
Masaryk University

Recruiting

COVID-19 Vaccines Safety Tracking (CoVaST)

Adverse Reaction to Vaccine | COVID19 Vaccine

Poland, Canada, United States, Croatia, Czechia, Estonia, Ethiopia, Germany, Ghana, Mexico, Portugal, Russian Federation, Serbia, Slovenia
Boehringer Ingelheim
Pfizer

Completed

A Randomised, Double- Blind, Placebo Controlled, Cross-over Efficacy and Safety Comparison of Tiotropium 5 µg Once Daily and Tiotropium 2.5 µg Twice Daily for Four Weeks in Patients With Moderate Persistent Asthma

Asthma

Austria, Czech Republic, Estonia, Germany, Latvia
AstraZeneca

Completed

Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis (STRATUS)

Bronchiectasis | Lung Disease | Respiratory Diseases

Czech Republic, United Kingdom, Poland
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of Capmatinib (INC280) Plus Pembrolizumab vs Pembrolizumab Alone in NSCLC With PD-L1≥ 50%

Non-small Cell Lung Cancer (NSCLC)

Japan, Germany, Spain, Italy, France, Thailand, Belgium, Netherlands, India, Malaysia, Taiwan, Australia, Canada, Czechia, Greece, Hong Kong

Clinical Trials on Lung Biopsy in Czechia

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