Clinical Trials on Lung Disease, Obstructive in United Kingdom

Total 147716 results

GlaxoSmithKline

Completed

Method Validation Study to Explore the Sensitivity of SenseWear Armband Gecko for Measuring Physical Activity in Subjects With Chronic Obstructive Pulmonary Disease (COPD) & Asthma

Pulmonary Disease, Chronic Obstructive

United Kingdom
Imperial College London

Withdrawn

Genomic/ Proteomic/ Metabonomic Profiling in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Absorption & Elimination of Radiolabelled GSK2269557

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

GSK573719 IV Enabling Study

Pulmonary Disease, Chronic Obstructive

United Kingdom
Imperial College London

Completed

Macrophage Phagocytosis in COPD

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
Theravance Biopharma
GlaxoSmithKline

Completed

Study of GSK961081 in Healthy Volunteer Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Safety, Tolerability and Pharmacokinetics (PK) Study of GSK2269557 in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

A Study to Assess the Safety and Pharmacokinetics of Inhaled Doses of GSK233705 and GW642444 in Healthy Subjects.

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Safety, Blood Levels and Effects of GW642444

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

A Study To Investigate Safety, Blood Levels And Effects Of Giving GW642444, By Mouth, By Inhalation & By Injection

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

QTc Study GSK573719+GW642444

Pulmonary Disease, Chronic Obstructive

United Kingdom
Breathe Technologies, Inc.

Completed

Non-invasive Ventilation System in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) (PRIDE)

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Lung Disease | Chronic Obstructive Airway Disease | Airflow Obstruction, Chronic

United States
Mologic Ltd
University Hospitals, Leicester

Terminated

COPD Exacerbation Alert System With urinE anaLysis Using the HEADSTART Device (COPE-WEL)

COPD Exacerbation

United Kingdom
MedImmune LLC

Completed

A Study to Evaluate the Safety of MEDI2338 in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom, South Africa
GlaxoSmithKline

Completed

To Assess the Excretion Balance and Pharmacokinetics of a Single Oral Dose of [14C]SB-681323 in Healthy Adult Males

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Clinical Study to Assess the Effects of SRT2104 and Prednisolone on Biomarkers in Blood in Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
Research in Real-Life Ltd
Sanofi

Completed

Handling Inhalers - Technique Error Comparison (HI-TEC) (HI-TEC)

Pulmonary Disease, Chronic Obstructive | Asthma

United Kingdom
Theravance Biopharma
GlaxoSmithKline; Hammersmith Medicines Research

Completed

A Phase 1 (Ph1), Single Dose (SD), GSK961081 Absorption, Distribution, Metabolism, and Excretion (ADME) Study in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

RELOVAIR® Lung Deflation Study

Pulmonary Disease, Chronic Obstructive

United Kingdom
Northumbria University
Newcastle-upon-Tyne Hospitals NHS Trust

Completed

Physical Activity Promotion Added to Standard Care Pulmonary Rehabilitation and Cognitive Behavioural Therapy

Chronic Obstructive Pulmonary Disease

United Kingdom
Imperial College London
Medical Research Council

Completed

Angiotensin-converting Enzyme (ACE)-Inhibition and Mechanisms of Skeletal Muscle Weakness in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Tetherex Pharmaceuticals Corporation

Completed

Study to Assess the Safety and Efficacy of SelK2 on Airway Responses Following Allergen Challenge in Subjects With Asthma (Part 1) and in Subjects With Chronic Obstructive Pulmonary Disease (Part 2)

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
AstraZeneca

Completed

Two-part Pharmacokinetic and Pharmacodynamic Study of LAS190792 in Patients With Asthma and COPD

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Breathe Technologies, Inc.

Completed

In-home Evaluation of a Noninvasive Open Ventilation System in Patients With Severe Respiratory Insufficiency

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Lung Disease | Chronic Obstructive Airway Disease | Airflow Obstruction, Chronic

United States
Chelsea and Westminster NHS Foundation Trust

Recruiting

Physiological and Environmental Data in a Remote Setting to Predict Exacerbation Events in Patients With Chronic Obstructive Pulmonary Disease (SENSOR)

COPD Exacerbation

United Kingdom
University of Leicester
Genentech, Inc.; Biomedical Research Centre- Respiratory (Glenfield Hospital...

Completed

Anti-ST2 (MSTT1041A) in COPD (COPD-ST2OP) (COPD-ST2OP)

COPD Exacerbation

United Kingdom
AstraZeneca
Parexel

Completed

A Single Inhalation Dose Study to Assess Efficacy, Pharmacokinetics (PK), Safety and Tolerability of AZD8871 in Patients With Long-term Lung Diseases.

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
Manchester University NHS Foundation Trust

Completed

Cough Responses to Tussive Agents in Health and Disease

Asthma | Chronic Cough | Chronic Obstructive Airway Disease

United Kingdom
Teesside University
South Tees Hospitals NHS Foundation Trust; North Tees and Hartlepool NHS Foundation...

Completed

The Relationship Between Pain, Balance and Gait in People With Chronic Obstructive Pulmonary Disease

Pain | Chronic Obstructive Pulmonary Disease | Balance Impairment | Gait Impairment

United Kingdom
Imperial College London
Duska Scientific Co.

Completed

ATP/AMP Challenge in Healthy Non-smokers, Smokers, Patients With Asthma, and Patients With Chronic Obstructive Pulmonary Disease (COPD)

Smoking | Asthma | COPD

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is Gait Speed and Sarcopenia Prognostic in Chronic Respiratory Disease?

Chronic Obstructive Pulmonary Disease and Allied Conditions

United Kingdom
University of Dundee
NHS Tayside; NHS Fife; Chief Scientist Office of the Scottish Government

Completed

Do Phosphodiesterase 5A Inhibitors Improve Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Pulmonary Hypertension?

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

United Kingdom
GlaxoSmithKline

Completed

Effect of GSK704838 In Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Effect of GSK1160724 In Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

A Study to Assess the Safety and Pharmacokinetics of Inhaled Doses of GSK233705 and GW642444 in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
Novartis Pharmaceuticals

Completed

QVA Mechanistic Efficacy Study (Receptor Effects, Etc)

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca

Completed

A Real-World Assessment of a COPD Disease Management Support Service (Me & My COPD) (Me&MyCOPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Dundee
Boehringer Ingelheim; NHS Tayside

Completed

INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation With Tiotropium and Olodaterol (INCOGNITO)

Chronic Obstructive Pulmonary Disease

United Kingdom
London School of Hygiene and Tropical Medicine
University College, London; British Medical Research Council

Completed

Survival After First Myocardial Infarction in Patients With and Without Chronic Obstructive Pulmonary Disease

Myocardial Infarction | Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca
University of Oxford

Completed

Study of Relationship Between Changes in Inflammation, Lung Function, Symptoms and Medication Use in COPD Patients (CORAL)

Pulmonary Disease, Chronic Obstructive

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

The Effect of Two Weeks of Voluntary Reduced Physical Activity in Chronic Obstructive Pulmonary Disease (COPD)

Muscle Atrophy | Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
GlaxoSmithKline

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of GSK2256294 in Healthy Volunteers, and Single and Repeat Doses of GSK2256294 in Adult Male Moderately Obese Smokers

Pulmonary Disease, Chronic Obstructive

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD (COPD-ENVIRON)

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
University of Cambridge; Pneumacare Ltd

Completed

Structured Light Plethysmography in Obstructive Airways Disease

Pediatric Respiratory Diseases

United Kingdom
GlaxoSmithKline

Completed

A Study to Look at Day to Day Changes in Lung Function in COPD Subjects Taking Albuterol/Salbutamol and Ipratropium

Pulmonary Disease, Chronic Obstructive

United States, United Kingdom
University of Dundee
AstraZeneca; NHS Tayside

Completed

Microbiome Use to Stratify Use of Inhaled Corticosteroids: MUSIC Trial (MUSIC)

Chronic Obstructive Pulmonary Disease

United Kingdom
GlaxoSmithKline

Completed

Study of Safety and Drug Levels of CCI15106 Inhalation Powder in Healthy Adults and Adults With Moderate Chronic Obstructive Pulmonary Disease. Study of CCI15106 Levels in People Standing Near the Person Inhaling the Drug

Pulmonary Disease, Chronic Obstructive

United Kingdom
Barcelona Institute for Global Health
KU Leuven; University Medical Center Groningen; University of Athens; University... and other collaborators

Completed

Non-interventional Cross-over Study to Reduce Items of PROactive Tools Measuring Physical Activity in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

Netherlands, Greece, Belgium, United Kingdom
AstraZeneca
RTI Health Solutions

Completed

A Drug Utilisation Post-authorisation Study of New Users of Aclidinium Bromide (Monotherapy or in Combination) (DUS1/DUS2)

Pulmonary Disease, Chronic Obstructive

Denmark, Germany, United Kingdom
Imperial College London

Recruiting

Activity, Balance and COPD (ABCOPD) (ABCOPD)

COPD

United Kingdom

Clinical Trials on Lung Disease, Obstructive in United Kingdom

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