Clinical Trials on Lung Disease,Obstructive in South Africa

Total 18736 results

Nuvaira, Inc.

Completed

Innovative Pulmonary Solutions (IPS) System for Targeted Lung Denervation (IPS-I)

Chronic Obstructive Pulmonary Disease (COPD)

Netherlands, South Africa
MedImmune LLC

Completed

A Study to Evaluate the Safety of MEDI2338 in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom, South Africa
University of Limpopo

Unknown

Effect of Vitamin D Supplementation on the Control of Asthma in Children at a South African Academic Hospital

Persistent Asthma

South Africa
GlaxoSmithKline

Completed

A 2 Part Study Examining Doses Of GSK961081 In Healthy Volunteers And Then In COPD Patients

Pulmonary Disease, Chronic Obstructive

South Africa, Germany
Chris Hani Baragwanath Academic Hospital

Terminated

High Flow Oxygen Therapy vs Standard Care in Infants With Viral Bronchiolitis

Bronchiolitis, Viral

South Africa
University of Limpopo

Unknown

Effect of Vitamin D Supplementation in Young South African Children Hospitalized With Acute Lower Respiratory Infection

Pneumonia | Bronchiolitis | Acute Lower Respiratory Tract Infection

South Africa
GlaxoSmithKline

Completed

Prednisolone Novel Endpoint Study in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Argentina, Chile, South Africa, New Zealand
Boehringer Ingelheim

Completed

Pilot Study Comparing Tiotropium (Spiriva) to Salmeterol (Serevent) Plus Fluticasone (Flixotide) in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

South Africa
AstraZeneca

Completed

Efficacy and Safety of Roflumilast Taken in the Morning or Evening in Patients With Stable Asthma (12 to 70 y) (BY217/M2-015)

Asthma

France, South Africa, Spain, Australia, Belgium
Novartis

Completed

Safety and Tolerability of Omalizumab in Patients With Mild to Moderate Asthma

Asthma

Germany, South Africa
ElectroCore INC

Terminated

Noninvasive Neurostimulation of the Vagus Nerve for the Relief of Acute Bronchoconstriction Due to Asthma (BC-SA-01)

Asthma

South Africa
GlaxoSmithKline

Completed

Clinical Endpoint Trial Investigating Once Daily and Bronchodilator Dosing

Asthma

New Zealand, South Africa
Novartis Pharmaceuticals

Completed

Study to Compare the Pharmacokinetics of Mometasone Furoate Alone and in Combination With Indacaterol in Patients ≥ 6 to < 12 Years Old With Asthma

Asthma

South Africa, Hungary
Novartis
Genentech, Inc.; Tanox

Completed

A Study of Efficacy of New Doses of Xolair to Protect From Allergen Challenge in Groups of Asthma Patients Defined by IgE Levels

Asthma

Germany, Netherlands, South Africa
AstraZeneca

Completed

The HERO-study: Effects of Roflumilast in Patients With COPD (Chronic Obstructive Pulmonary Disease) (BY217/M2-121)

Chronic Obstructive Pulmonary Disease, COPD

France, Poland, South Africa, Spain, United States, Canada, United Kingdom
AstraZeneca
Amgen

Completed

Study to Evaluate the Pharmacokinetics of Tezepelumab in Children With Asthma (TRAILHEAD)

Asthma

United Kingdom, South Africa, Hungary
Novartis

Completed

A Crossover Study to Determine the Effect on Lung Function of Indacaterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD), Using Tiotropium as an Active Control

Chronic Obstructive Pulmonary Disease (COPD)

Spain, Germany, South Africa, Australia, Poland, New Zealand, Netherlands
AstraZeneca

Completed

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease. Ratio-Study. (BY217/M2-112)

Chronic Obstructive Pulmonary Disease | COPD

Austria, France, Hungary, Italy, Poland, Portugal, Russian Federation, South Africa, Spain, Canada, United Kingdom, Australia, Netherlands, Switzerland
AstraZeneca

Completed

Efficacy of Ciclesonide Inhaled Once Daily Versus Other Corticosteroids Used for Treatment of Mild Asthma in Children (4 to 11 Years) (BY9010/CA-101) (POPCICLE)

Asthma

Canada, Hungary, South Africa
Mundipharma Research Limited

Completed

A Study to Show That Flutiform is Well Tolerated and Effective in the Treatment of COPD

Chronic Obstructive Pulmonary Disease

Ukraine, United Kingdom, Spain, Bulgaria, South Africa, Russian Federation, Germany, Hungary, Lithuania, Slovakia, Macedonia, The Former Yugoslav Republic of, Latvia, Romania, Korea, Republic of, Poland
Queen Mary University of London
National Institute for Health Research, United Kingdom

Completed

Achieving Control of Asthma in Children In Africa (ACACIA)

Asthma

Ghana, Malawi, Nigeria, South Africa, Uganda, Zimbabwe
GlaxoSmithKline

Completed

Dose-Finding Study of Batefenterol (GSK961081) Via Dry Powder Inhaler in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, United States, South Africa
University of Witwatersrand, South Africa

Active, not recruiting

A Cross-sectional, Observational Study to Characterise Long COVID-19 in an Urban Sample of South African Adults (ChaLOC)

Long COVID

South Africa
AstraZeneca

Completed

Efficacy and Safety of Ciclesonide (CIC) Administered Twice Daily in Pediatric Patients With Asthma.

Asthma

Russian Federation, Hungary, South Africa, Mexico, United States, Poland
Heidelberg University

Terminated

Correlation of FeNO, Blood Eosinophils, Bronchoalveolar Lavage Findings and Bronchial Epithelium Histopathology in Patients With Chronic Obstructive Pulmonary Disease and Asthma

Obstructive Lung Diseases

Australia, Germany
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-1029 in Participants With Mild to Moderate Asthma

Asthma

United States, Australia, New Zealand, South Africa
University of KwaZulu
AstraZeneca; Medical Research Council, South Africa

Unknown

Paediatric and Adult African Spirometry II (PAASII)

Lung Diseases

South Africa
Mylan Inc.
Theravance Biopharma

Completed

A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Mylan Inc.
Theravance Biopharma

Completed

Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD) (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
The George Institute
National Health and Medical Research Council, Australia

Completed

Theophylline and Steroids in Chronic Obstructive Pulmonary Disease (COPD) Study (TASCS)

Chronic Obstructive Pulmonary Disease

Australia
Mylan Inc.
Theravance Biopharma

Completed

A 28-Day Parallel Group Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States
Sheffield Teaching Hospitals NHS Foundation Trust
Novartis

Completed

SILO2 (Signal Intensity Lung washOut) (SILO2)

Chronic Obstructive Pulmonary Disease

United Kingdom
Macquarie University, Australia

Completed

The Use of Aeriseal ® in the Management of Collateral Ventilation Positive COPD Patients Undergoing ELVR Utilizing Endobronchial Valves.

Chronic Obstructive Pulmonary Disease (COPD)

Australia
Pearl Therapeutics, Inc.

Completed

Study to Evaluate the Safety and Efficacy of Inhaled PT005 in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Australia, New Zealand
AstraZeneca

Completed

Pharmacokinetic, Safety and Tolerability Study of Aclidinium/Formoterol Fixed Dose Combination and Formoterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Alexza Pharmaceuticals, Inc.

Completed

Staccato Loxapine Pulmonary Safety in Patients With COPD

Chronic Obstructive Pulmonary Disease

United States
Endo Pharmaceuticals
Alkermes, Inc.

Completed

Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
Pearl Therapeutics, Inc.

Completed

PT005 MDI Dose Ranging Versus Foradil Aerolizer Study

Chronic Obstructive Pulmonary Disease

United States
Nephron Pharmaceuticals Corporation
Rho, Inc.

Completed

Tiotropium Bromide Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Completed

COVID-19 Treatment in South Africa

COVID-19

South Africa
Pearl Therapeutics, Inc.

Completed

Efficacy and Safety Study of Two Dose Levels of AZD2115 in Subjects With Moderate to Severe COPD

Chronic Obstructive Pulmonary Disease (COPD)

United States
Pfizer

Completed

A Phase II, Study To Evaluate The Efficacy And Safety Of PH-797804 In Adults With Moderate To Severe Chronic Obstructive Pulmonary Disease (COPD).

Chronic Obstructive Pulmonary Disease

Australia, Netherlands, Canada, Korea, Republic of, Argentina, Hungary, South Africa, France, Russian Federation, Chile, Czechia, Greece, United Kingdom
ImmunityBio, Inc.

Active, not recruiting

COVID-19 Vaccination Using a 2nd Generation (E1/E2B/E3-Deleted) Adenoviral Platform in Healthy South African Adults

Covid19

South Africa
ImmunityBio, Inc.

Terminated

THEMBA II T-Cell Vaccine: Vaccination With saRNA COVID-19 Vaccines

COVID-19

South Africa
AstraZeneca

Completed

Roflumilast Plus Montelukast in Adults With Severe Asthma

Asthma

Germany, South Africa, Hungary
Johns Hopkins University

Completed

Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB

Tuberculosis, Pulmonary

South Africa
AstraZeneca

Completed

A Phase IIa Study to Investigate the Efficacy and Safety of AZD7624 in Chronic Obstructive Pulmonary Disease (COPD) Patients While on Maintenance Therapy

Chronic Obstructive Pulmonary Disease COPD

United States, Netherlands, Argentina, South Africa, Chile, Peru
University of California, Los Angeles
Fenzian Ltd.

Completed

Fenzian Asthma Multicenter Outcomes Study (FAMOUS)

Asthma

United States, South Africa, United Kingdom
Monash University
University of Melbourne; La Trobe University; Institute for Breathing and Sleep... and other collaborators

Recruiting

An Implementation Trial to Improve Access to Pulmonary Rehabilitation in People With COPD (HomeBase2)

Chronic Obstructive Pulmonary Disease

Australia
GlaxoSmithKline

Completed

Drug Interaction Study to Investigate Co-administration of GW642444M With Ketoconazole

Pulmonary Disease, Chronic Obstructive

Australia

Clinical Trials on Lung Disease,Obstructive in South Africa

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