Clinical Trials on MDMA Mechanism of Action

Total 248 results

California Pacific Medical Center Research Institute

Completed

Role of Serotonin in Acute and Subacute MDMA Effects

MDMA Mechanism of Action

United States
Brigham and Women's Hospital
Harvard Medical School (HMS and HSDM)

Recruiting

Revisiting the Mechanism of the Anti-inflammatory Effect of Colchicine

Colchicine Mechanism of Action

United States
Balance Therapeutics

Completed

A Study to Investigate the Mass Balance of BTD-001 (HV103)

Molecular Mechanisms of Pharmacological Action

United Kingdom
University of Malaya
Ministry of Health, Malaysia

Unknown

Pharmacometabolomics of Andrographis Paniculata And Metformin In Healthy Volunteers Under Fasting Condition

Pharmacokinetics | Molecular Mechanisms of Pharmacological Action

Malaysia
King Faisal Specialist Hospital & Research Center
King AbdulAziz City for Science and Technology

Completed

Measuring Placebo Effect by Elimination and Investigating Mechanism of Action

Placebo Effect | Placebo Mechanisms of Action

Saudi Arabia
Takeda

Completed

A Phase 1 Positron Emission Tomography Study to Measure Cholesterol 24S-Hydroxylase Target Occupancy of TAK-935

Epilepsy, Molecular Mechanisms of Pharmalogical Action, Protective Agents

United States
University of Maryland, Baltimore

Completed

Low-Dose Galantamine to Potentiate the Attention-Enhancing Effects of Low-Dose Nicotine (GalaNic)

Basic Science Study of the Mechanisms of Attentional Enhancement by Compounds Acting on the Nicotinic Receptor

United States
Felix Mueller
Swiss Society for Psycholytic Therapy (SÄPT)

Enrolling by invitation

The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training (TherPsySE)

Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD

Switzerland
University of Oxford

Completed

Effects of Seven Day Prucalopride Administration in Healthy Volunteers

Mental Disorders | Depressive Disorder | Depression | Mood Disorders | Molecular Mechanisms of Pharmacological Action | Cognition | Antidepressive Agents

United Kingdom
University of Oxford
University of Bath

Unknown

Citalopram and Self Emotional Processing

Depressive Disorder | Depression | Molecular Mechanisms of Pharmacological Action | Mental Disorder | Cognition | Antidepressive Agents

United Kingdom
University of Oxford

Completed

Effects of Acute Prucalopride Administration in Healthy Volunteers

Depressive Disorder | Depression | Mood Disorders | Molecular Mechanisms of Pharmacological Action | Mental Disorder | Cognition | Antidepressive Agents

United Kingdom
Fudan University

Not yet recruiting

The Maintenance Treatment of Apatinib/Capecitabine Versus Observation in Advanced Gastric Cancer

Neoplasms | Stomach Neoplasms | Gastrointestinal Neoplasms | Digestive System Neoplasms | Stomach Diseases | Molecular Mechanisms of Pharmacological Action | Capecitabine | Apatinib
Second Affiliated Hospital of Wenzhou Medical University

Unknown

Acceptable Hemodynamic Changes in Dexmedetomidine for Single Intravenous Bolus Injection

Mental Disorders | Pathologic Processes | Postoperative Complications | Delirium | Neurocognitive Disorders | Dexmedetomidine | Molecular Mechanisms of Pharmacological Action | Physiological Effects of Drugs | Analgesics | Hypnotics and Sedatives

China
Institut National de la Santé Et de la Recherche...

Completed

Pharmacology Space Kit (PSK) - Dried Blood Spot for Caffeine Pharmacokinetics Under Microgravity Conditions (PSK)

Metabolism Medication Toxicity | Space Motion Sickness | Drug Mechanism

France
Centre for Addiction and Mental Health

Completed

Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence

Smoking Cessation | Tobacco Smoking | Tobacco Use Disorder | Substance Use Disorders | Molecular Mechanisms of Pharmacological Action | Tobacco Dependence | Physiological Effects of Drugs

Canada
Luye Pharma Group Ltd.

Completed

Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Schizophrenia Spectrum and Other Psychotic Disorders | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Neurotransmitter Agents | Central...

United States
Meir Medical Center

Unknown

The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies

High Risk Pregnancies | Telomere Length | Mechanisms of Telomter Homeostasis

Israel
Luye Pharma Group Ltd.

Completed

Relative Bioavailability of LY03010 Compared to Listed Drug

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Central Nervous System Depressants | Neurotransmitter Agents | Schizophrenia Spectrum

United States
Theodor Bilharz Research Institute

Completed

Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure

Lack of Drug Action

Egypt
Matias Vested

Completed

Mivacurium 0.2 mg/kg in Young (18 - 40 Years) and Elderly (= 80 Years) Patients

Onset Time of Mivacurium, Duration of Action of Mivacurium

Denmark
Second Affiliated Hospital, School of Medicine,...

Unknown

MRI Study of Antidepressants in the Treatment of Refractory Functional Dyspepsia

Therapeutic Mechanism of Antidepressants for Refractory FD

China
Guizhi Du

Recruiting

The Effects of General Anesthetics on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and Mechanism Involved

Colorectal Cancer Metastatic | Survival Rate | General Anesthetics Toxicity | Lymphocyte Destruction | Molecular Mechanism of Pharmacological Action

China
Sunnybrook Health Sciences Centre
University Health Network, Toronto; McMaster University; London Health Sciences...

Recruiting

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients (CODEX)

Mental Disorders | Nervous System Diseases | Neurologic Manifestations | Delirium | Confusion | Neurobehavioral Manifestations | Neurocognitive Disorders | Cognitive Dysfunction | Dexmedetomidine | Molecular Mechanisms of Pharmacological Action | Signs and Symptoms | Physiological Effects of Drugs | Analgesics,... and other conditions

Canada
Tianjin Medical University General Hospital

Not yet recruiting

Propranolol on Post Stroke Immune Status and Infection

Cardiovascular Diseases | Stroke | Cerebrovascular Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Ischemic Stroke | Molecular Mechanisms of Pharmacological Action | Physiological Effects of Drugs | Propranolol | Immunologic Factors | Beta Blocker

China
Matias Vested

Completed

An Observational Study of Cisatracurium 0.15 mg/kg in Young and Elderly (≥ 80 Years) Patients.

Intubation Conditions | Onset Time of Cisatracurium | Duration of Action of Cisatracurium

Denmark
Sichuan Cancer Hospital and Research Institute

Recruiting

TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC

Liver Diseases | Digestive System Neoplasms | Liver Neoplasms | Hepatocellular Carcinoma | Antineoplastic Agents | Molecular Mechanisms of Pharmacological Action | Protein Kinase Inhibitors | Sorafenib

China
China Medical University Hospital

Completed

Study on the Effect of Electroacupuncture at Both Zusanli and at Both Yanglingquan Acupoints on Cardiovascular Activity

Reaction of Autonomic Nervous System | Reaction of Acupuncture | Reaction of Blood Circulation

Taiwan
China Medical University Hospital

Completed

The Difference Between Acupuncture and Far-infrared Ray Illumination at CV12 Acupoint

Reaction of Autonomic Nervous System | Reaction of Acupuncture | Reaction of Far Infrared Ray

Taiwan
National Cancer Institute, Slovakia
Merck KGaA, Darmstadt, Germany

Completed

Avelumab in Refractory Testicular Germ Cell Cancer.

Neoplasms | Gonadal Disorders | Neoplasms, Germ Cell and Embryonal | Testicular Neoplasms | Testicular Diseases | Antineoplastic Agents | Molecular Mechanisms of Pharmacological Action

Slovakia
China Medical University Hospital

Completed

Far-infrared Ray Effect on CV12 Acupoint

Reaction of Far Infrared Ray | Reaction of Skin Temperature

Taiwan
Reinier Haga Orthopedisch Centrum
Delft University of Technology

Recruiting

Propagation Waves in Tactile Material Perception

Sensory Processing | Perception | Sense of Touch | Taction

Netherlands
Celularity Incorporated

Terminated

Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM (CYNK001GBM01)

Glioblastoma Multiforme | Molecular Mechanisms of Pharmacological Action | Giant Cell Glioblastoma | Astrocytoma, Grade IV | Physiological Effects of Drugs | Peripheral Nervous System Agents | Analgesics | Analgesics, Non-narcotic | Cyclophosphamide | Immunosuppressive Agents | Immunologic Factors | Antiviral... and other conditions

United States
Tianjin Medical University

Terminated

Clinical Research on Retinal Neovascularization of Diabetic Retinopathy

The Mechanism of Retinal Neovascularization of Diabetic | Retinopathy.

China
Danish Headache Center

Completed

The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.

Headache | Dilatation of Cranial Arteries; MMA, STA and MCA

Denmark
Methodist University, North Carolina

Completed

Accuracy of Visual Range of Motion Estimates

Accuracy of Estimation of Joint Range of Motion

United States
Philippe Gauthier

Completed

Pericapsular Nerve Group Block: An Imaging Study for Determination of the Spread of the Injectate Using 3-D CT Scan

Post Operative Pain | Mechanisms of Analgesia

Belgium
Saime Nilay Arman

Completed

KinectROM Application for Assessing Range of Motion in Upper and Lower Extremity: A Development and Validation Study (KinectROM)

Range of Motion

Turkey
Natural Immune Systems Inc

Completed

Evaluation of Activity Levels, Inflammatory Markers, and Overall Wellness. (114-012)

Range of Motion

United States
Istanbul University

Completed

An Objective Measurement Method With The Leap Motion Sensor For Hand And Wrist's Range Of Motion

Range of Motion
Maimonides Medical Center

Recruiting

Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome (PWS-GXR)

Aggression | Behavioral Symptoms | Pathologic Processes | Nervous System Diseases | Obesity | Neurologic Manifestations | Neurobehavioral Manifestations | Congenital Abnormalities | Overnutrition | Nutrition Disorders | Genetic Diseases, Inborn | Intellectual Disability | Self-Injurious Behavior | Abnormalities, Multiple and other conditions

United States
Mansoura University

Completed

Robson Classification of Indications of Cesarean Section at MUH

Indication of Cesarean Section

Egypt
Federal University of Rio Grande do Sul

Completed

Passive Static Stretching and Proprioceptive Neuromuscular Facilitation in Musculoskeletal Aspects

Range of Motion | Flexibility
Universidade Federal do vale do São Francisco
Universidade Federal do Rio Grande do Norte; University of Pernambuco

Completed

Capoeira Training and Flexibility

Range of Motion | Flexibility

Brazil
Logan College of Chiropractic

Unknown

Cervical Stairstep and Effects on Range of Motion (ROM) (CSEROM)

Range of Motion, Articular

United States
Assiut University

Not yet recruiting

Enhanced Recovery After Cesarean Section

Cesarean Section | Quality Of Care
Gdansk University of Physical Education and Sport

Completed

Effect of Whole-body Vibration on the Ankle Joint, Plantar Pressure, and Running Paramethers

Gait | Running | Range of Motion

Poland
Konya Meram State Hospital

Completed

Relationship Between Analgesia Techniques and Post-cesarean Recovery Quality

Cesarean Section | Quality of Recovery

Turkey
Coombe Women and Infants University Hospital

Completed

Validation of an Obstetric QoR Score and to Establish Its MCID.

Caesarean Section | Quality of Recovery

Ireland
Naval Aeromedical Research Unit, Dayton

Unknown

Study of the Safety and Efficacy of DPI-386 Nasal Gel on Ocean-Going Vessels (INSCOP)

Prevention of Nausea Associated With Motion Sickness | Treatment of Nausea Associated With Motion Sickness

United States
University of Virginia

Completed

Standard Tubal Ligation Versus Salpingectomy for Sterilization at the Time of Cesarean Delivery

Method of Tubal Ligation at the Time of Cesarean Section

United States

Clinical Trials on MDMA Mechanism of Action

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Sri Lanka

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations