Clinical Trials on MGMT-Unmethylated Glioblastoma
Total 1674 results
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National Cancer Institute (NCI)CompletedGlioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-MutantUnited States, Canada
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Nuvation Bio Inc.TerminatedGlioma | Breast Cancer | Glioblastoma | Advanced Breast Cancer | Prostate Cancer | Metastatic Breast Cancer | Recurrent Glioblastoma | Breast Carcinoma | Castration-resistant Prostate Cancer | Prostate Neoplasm | Cancer of the Prostate | Prostatic Cancer | Glioma, Malignant | Cancer of Breast | Malignant Tumor of Breast and other conditionsUnited States
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Incyte CorporationBristol-Myers SquibbCompletedMelanoma | Lymphoma | Head and Neck Cancer | Glioblastoma | Ovarian Cancer | Lung Cancer | Colorectal Cancer (CRC) | B-cell MalignanciesUnited States, United Kingdom
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Ali AltunkayaNational Cancer Institute (NCI)TerminatedBrain and Central Nervous System Tumors | Cerebral EdemaUnited States
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Beth Israel Deaconess Medical CenterNational Cancer Institute (NCI)CompletedBrain and Central Nervous System Tumors | Metastatic Cancer | Melanoma (Skin)United States
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Northwell HealthRecruitingGlioma | Glioblastoma | Brain Cancer | Brain Tumor | Brain Neoplasm | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Brain Tumor, Recurrent | Brain Neoplasm, MalignantUnited States
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Andrew B Lassman, MDPfizer; AEterna ZentarisCompletedGlioblastoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Brain Tumor, Recurrent | Mixed GliomaUnited States
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AbbVieTerminatedGlioblastoma | Medullary Thyroid Cancer | Malignant Melanoma | Other Solid Tumors | Large-Cell Neuroendocrine Carcinoma | Neuroendocrine Prostate Cancer | High Grade Gastroenteropancreatic Neuroendocrine Carcinoma | Other Neuroendocrine CarcinomaUnited States
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Oliver Jonas, PhDRecruitingGlioblastoma | Astrocytoma | Anaplastic Oligodendroglioma | Anaplastic Astrocytoma of Brain | Grade III Glioma | Grade IV Glioma | Grade II Glioma | Oligodendroglioma of BrainUnited States
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Virginia Commonwealth UniversityNational Cancer Institute (NCI)Active, not recruitingGlioblastoma | Malignant Glioma | WHO Grade III Glioma | Recurrent Adult Brain NeoplasmUnited States
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Children's Hospital Medical Center, CincinnatiNovartisCompletedGlioblastoma | Malignant Glioma of Brain | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brainstem Glioma | Bithalamic High Grade GliomaUnited States
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Kartos Therapeutics, Inc.CompletedCancer | Glioblastoma | Multiple Myeloma | Advanced Solid Tumors | Oncology | Tumors | Advanced Malignancy | Oncology PatientsUnited States, France, Netherlands
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National Institute of Neurological Disorders and...CompletedGlioma | Glioblastoma | Brain Neoplasm | Pituitary NeoplasmUnited States
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University of BirminghamUniversity of Leeds; Jazz Pharmaceuticals; The Brain Tumour CharityRecruitingGlioblastoma | Brain Tumor | Cannabis | Brain Tumor, RecurrentUnited Kingdom
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Sheffield Teaching Hospitals NHS Foundation TrustUniversity of SheffieldRecruitingMelanoma | Sarcoma | Kidney Cancer | Head and Neck Cancer | Glioblastoma | Bladder CancerUnited Kingdom
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Washington University School of MedicineRecruitingGlioma | Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Pilocytic Astrocytoma | Mixed Oligoastrocytoma | Mixed Glioma | Optic GliomaUnited States
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National Cancer Institute (NCI)CompletedAdult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland... and other conditionsUnited States
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St. Jude Children's Research HospitalRecruitingGlioblastoma | Central Nervous System Neoplasms | High Grade Glioma | Ependymoma | Medulloblastoma | Diffuse Midline Glioma, H3 K27M-Mutant | Atypical Teratoid/Rhabdoid TumorUnited States
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Memorial Sloan Kettering Cancer CenterNational Cancer Institute (NCI)CompletedProstate Cancer | Brain and Central Nervous System TumorsUnited States, Spain
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Sidney Kimmel Comprehensive Cancer Center at Johns...CompletedGlioblastoma | Malignant Glioma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Astrocytoma, Grade III | Brain Stem Neoplasms, Malignant | OligodendroblastomaUnited States
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Guangdong Zhongsheng Pharmaceutical Co., Ltd.UnknownSmall Cell Lung Cancer | Glioblastoma | Medulloblastoma | Neuroendocrine Neoplasm | Basal Cell Carcinoma | Adenocarcinoma of Esophagogastric JunctionChina
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Novartis PharmaceuticalsTerminatedGlioblastoma | Anaplastic Large Cell Lymphoma | Inflammatory Myofibroblastic Tumor | Tumors With Aberrations in ALKFrance, Czechia, Italy, Spain, Korea, Republic of, Thailand, Israel, Denmark
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DNAtrix, Inc.Merck Sharp & Dohme LLCCompletedNervous System Diseases | Glioma | Glioblastoma | Neuroectodermal Tumors | Brain Cancer | Gliosarcoma | Brain Neoplasm | Malignant Brain Tumor | Neoplasm, Neuroepithelial | Neoplasm by Histologic Type | Neoplasm, Nerve TissueUnited States, Canada
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Sabine Mueller, MD, PhDNational Cancer Institute (NCI); Dana-Farber Cancer Institute; Mithil Prasad... and other collaboratorsRecruitingGlioblastoma | Recurrent Ependymoma | CNS Tumor | Diffuse Midline Glioma (DMG) | Recurrent Malignant Central Nervous System Neoplasm | Spinal Cord Glioma | Central Nervous System Tumor | World Health Organization (WHO) Grade III GliomaUnited States, Switzerland
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Memorial Sloan Kettering Cancer CenterColumbia University; Genentech, Inc.; University of California, San FranciscoCompletedGlioblastoma | Brain Cancer | Anaplastic Astrocytoma (AA) | Anaplastic Oligodendroglioma (AO) | MALIGNANT GLIOMA | Anaplastic Oligo-astrocytoma (AOA) | Anaplastic Mixed Gliomas | Malignant Glioma NOSUnited States
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Gregory K. Friedman, MDMemorial Sloan Kettering Cancer Center; United States Department of Defense; Food... and other collaboratorsCompletedGlioblastoma | Malignant Glioma | PNET | Anaplastic Astrocytoma | Embryonal Tumor | Supratentorial Neoplasms, Malignant | Cerebral Primitive Neuroectodermal TumorUnited States
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St. Jude Children's Research HospitalNovartis PharmaceuticalsActive, not recruitingGlioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditionsUnited States
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Merck Sharp & Dohme LLCEisai Inc.Active, not recruitingGlioblastoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Advanced Solid Tumors | Triple Negative Breast Cancer | Biliary Tract CancersUnited States, Argentina, Australia, Canada, Chile, Colombia, France, Germany, Israel, Italy, Korea, Republic of, Russian Federation, Spain, Switzerland, Taiwan, Thailand, United Kingdom
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Telix International Pty LtdRecruitingSoft Tissue Sarcoma | Cervical Cancer | Nasopharyngeal Carcinoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Glioblastoma Multiforme | Non Small Cell Lung Cancer | Cholangiocarcinoma | Epithelial Ovarian Cancer | Head and Neck Squamous Cell Carcinoma and other conditionsUnited States
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Gilead SciencesCompletedCervical Cancer | Urinary Bladder Neoplasms | Small Cell Lung Cancer | Hepatocellular Carcinoma | Pancreatic Cancer | Esophageal Cancer | Ovarian Epithelial Cancer | Glioblastoma Multiforme | Gastric Adenocarcinoma | Triple Negative Breast Cancer | Endometrial Cancer | Non-small Cell Lung Cancer | Renal Cell Cancer and other conditionsUnited States
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Dartmouth-Hitchcock Medical CenterCarl Zeiss Meditec, Inc.RecruitingGlioblastoma | Meningioma | Brain Metastases | Schwannoma | Pituitary Tumor | Glial TumorUnited States
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Hospices Civils de LyonRecruitingKidney Cancer | Head and Neck Cancer | Glioblastoma | Prostate Cancer | Cervix CancerFrance
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CelgeneCompletedLymphoma | Lymphoma, Large B-Cell, Diffuse | Glioblastoma | Multiple Myeloma | Primary Central Nervous System Lymphoma | Pleiotropic Pathway ModifierUnited States, Spain, Belgium, France, Italy
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Istari Oncology, Inc.Duke University; Solving Kids' Cancer; The Andrew McDonough B+ FoundationCompletedGlioblastoma | Malignant Glioma | Gliosarcoma | Ependymoma | Medulloblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Atypical Teratoid/Rhabdoid Tumor of Brain | Pleomorphic Xanthoastrocytoma of Brain | Embryonal Tumor of BrainUnited States
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xCuresCancer CommonsAvailableExpanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered MalignanciesMelanoma | Head and Neck Cancer | Glioblastoma | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Bladder Cancer | Thyroid Cancer | ERK Mutation | MAPK Gene Mutation | KRAS Activating... and other conditionsUnited States
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Ohio State University Comprehensive Cancer CenterAmerican Cancer Society, Inc.; Lance Armstrong FoundationCompletedDepression | Pain | Leukemia | Fatigue | Multiple Myeloma | Insomnia | Pancreatic Cancer | Esophageal Cancer | Lung Cancer | Glioblastoma Multiforme | Sleep Disorders | Uncertainty | Ovarian Neoplasm | Anxiety Disorder | Psychological Intervention | Relapsed Lymphoma | Worry | Cognitive-behavioral Therapy | Stage III or IV Cervical... and other conditionsUnited States
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Icahn School of Medicine at Mount SinaiPatient-Centered Outcomes Research InstituteCompletedMelanoma | Glioblastoma | Colorectal Cancer | Cancer of Pancreas | Cancer of Stomach | Head or Neck Cancer | Stage III | Esophageal | Stage IV | Lung Cancers | Pancreatic Cancers | Primary Stage IV HepatobiliaryUnited States
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Constantinos HadjipanayisNational Cancer Institute (NCI); NX PharmaGenWithdrawnGlioblastoma | Brain Cancer | Brain Tumors | Brain Tumor, Recurrent | Benign Neoplasms, Brain | Brain Neoplasms, Benign | Brain Neoplasms, Malignant | Brain Tumor, Primary | Intracranial Neoplasms | Neoplasms, Brain | Neoplasms, Intracranial | Primary Brain Neoplasms | Primary Malignant Brain Neoplasms | Primary Malignant... and other conditionsUnited States
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Rigel PharmaceuticalsNationwide Children's HospitalNot yet recruitingAstrocytoma | High Grade Glioma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | Spinal Tumor | Astrocytoma, Grade III | Astrocytoma, Grade IV | IDH1 Mutation | WHO Grade IV Glioma | Thalamus Tumor | IDH1 R132 | IDH1 R132C | IDH1 R132H and other conditionsUnited States, Australia, United Kingdom, Canada, Germany, Netherlands
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NGM Biopharmaceuticals, IncMerck Sharp & Dohme LLCRecruitingMelanoma | Renal Cell Carcinoma | Cervical Cancer | Breast Cancer | Glioblastoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Pancreatic Ductal Adenocarcinoma | Endocervical CancerUnited States, Korea, Republic of, Taiwan
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Black Diamond Therapeutics, Inc.RecruitingNon-Small Cell Lung Cancer | NSCLC | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | EGF-R Positive Non-Small Cell Lung Cancer | Advanced Lung Carcinoma | EGFR-TKI Resistant Mutation | Advanced Non-Small Cell Squamous Lung Cancer | Epidermal Growth Factor Receptor C797S | Epidermal...Korea, Republic of, United States
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Novartis PharmaceuticalsCompletedGlioblastoma | Astrocytoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma, Childhood and other conditionsUnited States, Italy, Japan, Germany, Spain, France, Canada, Australia, Brazil, Israel, Russian Federation, Argentina, United Kingdom, Finland, Belgium, Denmark, Czechia, Sweden, Switzerland, Netherlands
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AVM Biotechnology IncAvailableCancer | Breast Cancer | Glioblastoma | Gastric Cancer | Pancreatic Cancer | Hodgkin Lymphoma | Ovarian Cancer | Prostate Cancer | Acute Leukemia | Non-hodgkin Lymphoma | Squamous Cell Carcinoma | Tumor, Solid | Tumor, Brain | Spindle Cell Sarcoma
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Neonc Technologies, Inc.RecruitingMelanoma | Renal Cell Carcinoma | Cervical Cancer | Small Cell Lung Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Merkel Cell Carcinoma | Gastroesophageal Junction... and other conditionsUnited States
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CelgeneCompletedMelanoma | Sarcoma | Neoplasms | Lymphoma | Renal Cell Carcinoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Breast Cancer | Small Cell Lung Cancer | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Non-Small Cell Lung Cancer | Osteosarcoma | Glioblastoma Multiforme | Metastatic Breast... and other conditionsUnited States
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National Cancer Institute (NCI)CompletedRecurrent Childhood Medulloblastoma | Childhood High-grade Cerebral Astrocytoma | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Cerebellar Astrocytoma | Recurrent Childhood Cerebral Astrocytoma | Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor | Recurrent Childhood... and other conditionsUnited States
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University Hospital, AntwerpCompletedRenal Cell Carcinoma | Glioblastoma | Malignant Mesothelioma | Colorectal Tumors | Breast Cancers | SarcomasBelgium
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Cambridge University Hospitals NHS Foundation TrustUniversity of CambridgeTerminatedMelanoma | Soft Tissue Sarcoma | Renal Cell Carcinoma | Cervical Cancer | Breast Cancer | Small Cell Lung Cancer | Glioblastoma | Pancreatic Cancer | Ovarian Cancer | Non-small Cell Lung Cancer | Gastrointestinal CancerUnited Kingdom
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Genentech, Inc.23andMe, Inc.CompletedBreast Cancer | Glioblastoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Renal Cell CancerUnited States
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National Cancer Institute (NCI)Active, not recruitingRecurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Recurrent... and other conditionsUnited States