Clinical Trials on MPN (Myeloproliferative Neoplasms)

Total 106909 results

Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
National Cancer Institute (NCI)

Withdrawn

Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

Malignant Pleural Mesotheliomas (Mpm) | Malignant Pleural Effusions (Mpe) | Epithelial Tumors, Malignant | Pleural Effusions, Malignant | Mesothelin (Msln)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative...

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative...

United States
Northside Hospital, Inc.
Blood and Marrow Transplant Group of Georgia

Completed

Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
European Organisation for Research and Treatment...

Terminated

Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Neutropenia | Unspecified Adult Solid Tumor, Protocol Specific | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Fever, Sweats, and Hot Flashes | Myelodysplastic/Myeloproliferative Neoplasms

France, Switzerland, Belgium, Germany, Italy, Israel, Slovakia, Turkey
University Hospital, Clermont-Ferrand
Service de Biologie de la Reproduction : AMP-CECOS; EA 975, Laboratoire de BDR and other collaborators

Completed

Effects of Atorvastatin on Human Semen and Gonadal Hormones

Healthy Volunteers | Normocholesterolaemic Men | Normozoospermic Men

France
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Imatinib Mesylate in Treating Patients With Myelofibrosis

Chronic Myeloproliferative Disorders

United States
French Innovative Leukemia Organisation
French Intergroup of Myeloproliferative syndromes

Completed

COVID-19 Epidemic and Patients With Myeloproliferative Neoplasias (COVIM)

Myeloproliferative Neoplasm | COVID-19 Infection

France
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Collecting and Storing Tissue and DNA Samples From Patients Undergoing a Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United States
Vanderbilt University
National Cancer Institute (NCI)

Terminated

Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Chronic Myeloproliferative Disorders | Cancer Survivor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant

Acute Myeloid Leukemia | Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Plasma Cell Myeloma | Myelodysplastic/Myeloproliferative Neoplasm | Graft Versus Host Disease | Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States, Italy
Biotheus Inc.

Recruiting

A Study of PM8002 Injection in Combination With Standard Chemotherapy as First Line Therapy in MPM

MPM

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease | Precancerous/Nonmalignant Condition
Ehab L Atallah

Completed

Hypomethylating Properties of Freeze-dried Black Raspberries (BRB) in Patients With Myelodysplastic Syndrome or Myelodysplastic Syndrome/Myeloproliferative Neoplasm (MDS/MPN)

Myelodysplastic Syndromes

United States
University of Sydney

Completed

Composition of Functional Tooth Units and Nutrient Intake in Older Men (CHAMP)

Oral Health of Older Men | Dietary Assessment of Older Men

Australia
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Terminated

Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic Syndrome

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants

Acute Myeloid Leukemia | Primary Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Secondary Myelofibrosis

United States
Washington University School of Medicine
CTI BioPharma

Withdrawn

Pacritinib in Combination With Low Dose Decitabine in Intermediate-High Risk Myelofibrosis or Myeloproliferative Neoplasm (MPN)/Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Myeloproliferative Neoplasm | Atypical Chronic Myeloid Leukemia
OHSU Knight Cancer Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Research Study in Healthy Volunteers of Patients With Fanconi Anemia, Myeloproliferative Disorders, or Myeloma

Chronic Myeloproliferative Disorders | Fanconi Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

CC-4047 in Treating Patients With Myelofibrosis

Chronic Myeloproliferative Disorders | Secondary Myelofibrosis

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Withdrawn

Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers

Depression | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Psychosocial Effects of Cancer and Its Treatment | Myelodysplastic...
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Completed

Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myeloproliferative Neoplasm | Myeloblasts 10 Percent or More of Bone Marrow Nucleated Cells

United States
Roswell Park Cancer Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic-Myeloproliferative Diseases

United States
Mayo Clinic

Recruiting

Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT Study

Hematopoietic and Lymphoid Cell Neoplasm | Hodgkin Lymphoma | Thrombocytopenia | Deep Vein Thrombosis | Non-Hodgkin Lymphoma | Acute Leukemia | Plasma Cell Myeloma | Myeloproliferative Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Low-Dose Decitabine in Treating Patients With Symptomatic Myelofibrosis

Chronic Myeloproliferative Disorders | Secondary Myelofibrosis

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Azacitidine in Treating Patients With Myelofibrosis

Chronic Myeloproliferative Disorders | Secondary Myelofibrosis

United States
University Hospital, Montpellier

Withdrawn

HIV Prevention During Chemsex (Chemsex)

Men Having Sex With Other Men
Fondazione Italiana Sindromi Mielodisplastiche-ETS

Recruiting

Italian Network MDS Registry (FISM_registry)

Myelodysplastic-Myeloproliferative Diseases

Italy
Medical College of Wisconsin

Unknown

Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation

Sarcoma | Pain | Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Ovarian Cancer | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Oral Complications | Myelodysplastic/Myeloproliferative Neoplasms

United States
Sanofi

Completed

Phase 2 Study of SAR302503 in Patients With Myelofibrosis

Hematopoietic Neoplasm

United States
Sanofi

Completed

Phase III Study of SAR302503 in Intermediate-2 and High Risk Patients With Myelofibrosis (JAKARTA)

Hematopoietic Neoplasm

Austria, Germany, Italy, Spain, United Kingdom, France, Belgium, Israel, Sweden, Australia, United States, Lithuania, Portugal, Korea, Republic of, Singapore, Taiwan, Mexico, Brazil, Canada, Hungary, Ireland, Poland, Romania, Russian... and more
Paolo Corradini
University of Milan

Completed

Immunologic Response After Pandemic Influenza A (H1N1) Vaccine in Onco- Hematologic Patients

Lymphoma | Multiple Myeloma | Myeloproliferative Disease

Italy
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms | Nausea and Vomiting

United States
Inge Marie Svane

Completed

Dual Vaccine Trial in Myeloproliferative Neoplasms

Polycythemia Vera | Essential Thrombocythemia

Denmark
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

Neoplasms | Myeloproliferative Disorders | Essential Thrombocythemia | Myelofibrosis

United States, Spain, France, Canada
Fondazione per la Ricerca Ospedale Maggiore

Completed

Secondary Cancers in Myeloproliferative Neoplasms (MPN-K Study) (MPN-K)

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis

Israel, United Kingdom, Czechia, Germany, Italy, Spain
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Terminated

Jaktinib and Azacitidine In Treating Patients With MDS With MF or MDS/MPN With MF.

Myelodysplastic Syndromes | Myelofibrosis | Myeloproliferative Neoplasms

China
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Hodgkin Lymphoma | Myelodysplastic-Myeloproliferative Diseases | Acute Lymphoblastic Leukemia | Non Hodgkin Lymphoma | Acute Leukemia | Myeloproliferative Disorder

United States
Paulista University

Recruiting

Effects of Warm-up Intensity and Blood Flow Restriction

Healthy Men

Brazil
Federal University of Health Science of Porto Alegre

Completed

Phototherapy in Association to Resistance Training in the Elderly: the Effect on Muscle Strength, Muscle Mass and Functional Capacity

Elderly Men

Brazil
Heinrich-Heine University, Duesseldorf
The Cranberry Institute

Completed

Effects of Cranberry Consumption in Vascular Function in Healthy Individuals (Cranberry)

Healthy Men

Germany
H. Lundbeck A/S

Completed

D2 Dopamine Receptor Occupancy After Oral Dosing of Lu AF35700 in Healthy Men Using [11C]-PHNO as Tracer Compound

Healthy Men

United Kingdom
Yonsei University

Completed

Effects of Lycopene on Oxidative Stress and Markers of Endothelial Function Healthy Men

Healthy Men

Korea, Republic of
AstraZeneca

Completed

A First Time in Man, Study to Assess the Safety of AZD8329 After Single Ascending Oral Doses

Healthy Men

Sweden
M.D. Anderson Cancer Center

Completed

Clofarabine Plus Low-Dose Cytarabine for Patients With Higher-Risk Myelodysplastic Syndrome (MDS)

Leukemia | Myeloproliferative Diseases

United States
Imago BioSciences, Inc., a subsidiary of Merck...

Active, not recruiting

Extension Study of Bomedemstat (IMG-7289/MK-3543) in Participants With Myeloproliferative Neoplasms (IMG-7289-CTP-202/MK-3543-005)

Primary Myelofibrosis | Thrombocythemia, Essential

United States, Australia, Hong Kong, Germany, Italy, New Zealand, United Kingdom
Queen's University, Belfast
Mayo Clinic; University Hospital Southampton NHS Foundation Trust; University... and other collaborators

Completed

Myeloproliferative Neoplasms: an In-depth Case-control Study (MOSAICC)

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia

United Kingdom
National Cancer Institute (NCI)

Completed

Tipifarnib in Treating Patients With Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or Undifferentiated Myeloproliferative Disorders

Chronic Myelomonocytic Leukemia | Recurrent Disease | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable | Accelerated Phase of Disease | Chronic Phase of Disease

United States
M.D. Anderson Cancer Center

Terminated

Planned Donor Lymphocyte Infusion (DLI) After Allogeneic Stem Cell Transplantation (SCT)

Lymphoma | Leukemia | Myeloma | Myeloproliferative Diseases

United States

Clinical Trials on MPN (Myeloproliferative Neoplasms)

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