- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03287284
Phototherapy in Association to Resistance Training in the Elderly: the Effect on Muscle Strength, Muscle Mass and Functional Capacity
July 31, 2018 updated by: Bruno Manfredini Baroni, Federal University of Health Science of Porto Alegre
Phototherapy has been largely used in rehabilitation programs due to its analgesic, antiinflammatory and healing effects.
Lately, its effects of optimizing the results of resistance training on young individuals have been studied.
However, there is a lack of studies on its effect on the elderly population.
The objective of the present study is to verify the effect of Low-Level Laser Therapy (LLLT) on the results of resistance training in the elderly.
The study will be a randomized doubled-blinded controlled trial.
30 elderly men with age ranging from 60 to 80 years will be included and randomized between Placebo Group (placebo LLLT + Resistance Training) and LLLT Group (active LLLT + Resistance Training).
All volunteers will be submitted to a control period of four weeks before the beginning of the resistance training, which will have 12 weeks of duration.
The assessments will be done at baseline, after the control period and after the training period.
The training sessions will be performed twice a week and the training protocol will be performed with repetition maximum periodization.
The LLLT will be applied before the training sessions on eight points of the quadriceps muscles, leading to a total of 240 Joules on each leg.
The placebo LLLT will be applied on the same way, but with the equipment turned off.
The assessments will include muscle architecture by ultrasonography, muscle strength by isokinetic dynamometer and 1 Repetition Maximum test of leg-extension and leg-press exercises, and functional capacity by the 6-Minute Walking Test, 30s Sit to Stand Test, Timed Up-and-Go Test and Stair Ascent Test.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
30
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Pôrto Alegre, Brazil
- Universidade Federal do Rio Grande do Sul
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
60 years to 80 years (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
Male
Description
Inclusion Criteria:
- Elderly men with age ranging from 60 to 80 years in condition to participate in the strength training program.
Exclusion Criteria:
- Individuals who already participate in strength training programs;
- Individuals who participated in strength training programs less than three months before the beginning of the study;
- Individuals with any kind musculoskeletal injuries in the lower limbs that impair the performance of the exercises;
- Individuals with contraindications to the performance of high intensity exercises, such as cardiovascular or neurological diseases;
- Individuals with difficulties in understanding and/or performing the exercises;
- Individuals who did not attend to at least 85% of the sessions or had 02 consecutive absences and did not recover them.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Triple
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: LLLT Group
Active Low Level Laser Therapy application with a dose of 240 Joules before resistance training
|
Active application of Low Level Laser Therapy with a dose of 240 Joules
Resistance Training
|
Placebo Comparator: Placebo Group
Placebo Low Level Laser Therapy application before resistance training
|
Resistance Training
Placebo application of Low Level Laser Therapy
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Isokinetic peak torque of quadriceps muscle
Time Frame: Change from baseline in isokinetic peak torque at 12 weeks
|
Change from baseline in isokinetic peak torque at 12 weeks
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Leg-extension 1RM test
Time Frame: Change from baseline in leg-extension 1RM test at 12 weeks
|
Change from baseline in leg-extension 1RM test at 12 weeks
|
Leg-press 1RM test
Time Frame: Change from baseline in leg-press 1RM test at 12 weeks
|
Change from baseline in leg-press 1RM test at 12 weeks
|
Muscle architecture
Time Frame: Change from baseline in muscle architecture at 12 weeks
|
Change from baseline in muscle architecture at 12 weeks
|
Physical Function
Time Frame: Change from baseline in physical function at 12 weeks
|
Change from baseline in physical function at 12 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
March 6, 2017
Primary Completion (Actual)
December 22, 2017
Study Completion (Actual)
December 22, 2017
Study Registration Dates
First Submitted
September 15, 2017
First Submitted That Met QC Criteria
September 15, 2017
First Posted (Actual)
September 19, 2017
Study Record Updates
Last Update Posted (Actual)
August 1, 2018
Last Update Submitted That Met QC Criteria
July 31, 2018
Last Verified
July 1, 2018
More Information
Terms related to this study
Other Study ID Numbers
- 59328316.9.0000.5345
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
product manufactured in and exported from the U.S.
Yes
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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