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Clinical Trials on MSI-H/dMMR Tumors
Total 83 results
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Sidney Kimmel Comprehensive Cancer Center at Johns...Merck Sharp & Dohme LLCActive, not recruitingHigh Tumor Mutation Burden | High TMB (Tumor Mutation Burden) | MSS (Microsatellite Stable)United States
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Emory UniversityNational Cancer Institute (NCI); GlaxoSmithKline; National Institutes of Health...Active, not recruitingMicrosatellite Stable | Stage IV Colorectal Cancer AJCC v8 | RAS Wild Type | MSI-H Colorectal Cancer | Metastatic Microsatellite Stable Colorectal Carcinoma | Advanced Microsatellite Stable Colorectal CarcinomaUnited States
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Incyte CorporationActive, not recruitingCervical Cancer | Nasopharyngeal Carcinoma | Advanced Solid Tumors | Mesothelioma | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Sarcomatoid Renal Cell Carcinoma | Anal Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-H/dMMR Tumors | PD-L1 Amplified Tumor (9p24.1) | Urothelial... and other conditionsFinland, United States, United Kingdom, Belgium, Sweden, Denmark, Norway
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Cancer Institute and Hospital, Chinese Academy...RecruitingBevacizumab | Capecitabine | Metastatic Colorectal Cancer (mCRC) | Oxaliplatin | Tislelizumab | First-Line | MSS/pMMR | RAS-mutatedChina
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Institut Mutualiste MontsourisInstitut National de la Santé Et de la Recherche Médicale, FranceRecruitingRenal Cell Carcinoma | Cancer | Bladder Cancer | MSI-H CancerFrance
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23andMe, Inc.Active, not recruitingClear Cell Renal Cell Carcinoma | Fallopian Tube Cancer | Solid Tumor | Neuroendocrine Tumors | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma | Extensive-stage Small-cell Lung Cancer | MSI-H Cancer | Cancer With A High Tumor Mutational BurdenUnited States, Canada
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Shanghai Junshi Bioscience Co., Ltd.Sponsor GmbHRecruitingLiver Cancer, Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma, Cervical Cancer, MSI-H Colorectal CancerChina
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Yunnan Cancer HospitalBeijing Bethune Charitable FoundationRecruitingEnvafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal CancerChina
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Jules Bordet InstituteRecruitingMelanoma | Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Non Small Cell Lung Cancer | Mesothelioma, Malignant | Bladder Cancer | Gastrointestinal Cancer | Merkel Cell Carcinoma | Non-melanoma Skin Cancer | MSI-H Colorectal CancerBelgium
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Novartis PharmaceuticalsRecruitingMSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal CancersJapan, Spain, Singapore, Belgium, Germany, Korea, Republic of, Taiwan, France, Israel, Norway, United States
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Atreca, Inc.TerminatedMelanoma | Breast Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Acral Lentiginous Melanoma | Platinum-Resistant Fallopian... and other conditionsUnited States
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Centre Hospitalier St AnneRecruitingMental Disorders | MRI | Stroke | Brain Tumor | NeurosciencesFrance
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Institut BergoniéBayer; Merck KGaA, Darmstadt, GermanyRecruitingHepatocellular Carcinoma | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Soft-tissue Sarcoma | Urothelial Carcinoma | Thyroid Cancer | Gastro-enteropancreatic Neuroendocrine Tumor | Biliary Tract Cancer | HPV-Related Carcinoma | Solid Tumor, Adult | Mesotheliomas Pleural | GIST | Renal Carcinoma | Colorectal... and other conditionsFrance
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Sidney Kimmel Comprehensive Cancer Center at Johns...Bristol-Myers Squibb; BayerActive, not recruitingColon Cancer | Unresectable or Metastatic Microsatellite Stable (MSS) Solid Tumor Along With Microsatellite Stable (MSS) Colon CancerUnited States
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Saint Vincent's Hospital, KoreaCompletedGastric Cancer | EBV Infection | MSIKorea, Republic of
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Celldex TherapeuticsCompletedRenal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Cholangiocarcinoma | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Hepatic Cancer | Bladder Urothelial Carcinoma | Other Solid Tumors | MSI-H Colorectal CancerUnited States
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AZ Sint-Jan AVActive, not recruitingHead and Neck Cancer | Multiparametric MRI | Cervical Lymph Node | Treatment Response | Bone Invasion | Tumour RelapseBelgium
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Evelo Biosciences, Inc.Merck Sharp & Dohme LLC; SCRI Development Innovations, LLCCompletedRenal Cell Carcinoma | Non Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | Colorectal Cancer Metastatic | GastroEsophageal Cancer | MSI-HUnited States, Canada
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Zhujiang HospitalRecruitingHigh Grade Glioma | Radiation Toxicity | Overall Survival | Progression-free Survival | MRI Simulated PositioningChina
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George Emil Palade University of Medicine, Pharmacy...RecruitingMRI | Diffusion Tensor Imaging | TractographyRomania
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Chinese PLA General HospitalRecruiting
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InvestigatorUrologyIBSALInstituto de Investigación Biomédica de SalamancaUnknownEstablish the Efficacy Between the Four Schemes in Terms of the Aggressiveness of the Tumors According to the Gleason Classification | Establish the Efficacy Between the Four Schemes in Terms of Morbidity Associated With the Technique | Establish the Efficacy Between the Four Schemes... and other conditionsSpain
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Incyte CorporationCompletedMelanoma | Breast Cancer | Head and Neck Cancer | Pancreatic Cancer | Lung Cancer | Endometrial Cancer | Solid Tumors | Renal Cell Carcinoma (RCC) | Colorectal Cancer (CRC) | UC (Urothelial Cancer) | MMR-deficient TumorsUnited States
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NuCana plcRecruitingMelanoma | Renal Cell Carcinoma | Gastric Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Neoplasm Malignant | Pleural... and other conditionsUnited Kingdom
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7 Hills Pharma, LLCNot yet recruitingMelanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditionsUnited States
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Incyte Biosciences International SàrlCompletedCervical Cancer | Hepatocellular Carcinoma | Esophageal Cancer | Ovarian Cancer | Mesothelioma | Non-small Cell Lung Cancer (NSCLC) | Urothelial Carcinoma | Merkel Cell Carcinoma | Diffuse Large B-cell Lymphoma | Triple-negative Breast Cancer | Renal Cell Carcinoma (RCC) | Small Cell Lung Cancer (SCLC) | Squamous... and other conditionsUnited States
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Incyte CorporationCompletedMelanoma | Renal Cell Carcinoma | Cervical Cancer | Stomach Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | NSCLC | Mesothelioma | Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer | Gastroesophageal Junction Cancer | Urothelial... and other conditionsUnited States
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SOLTI Breast Cancer Research GroupNovartisRecruitingMelanoma | Sarcoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Pancreatic Adenocarcinoma | Uterine Carcinosarcoma | Mesothelioma | Cholangiocarcinoma | Lung Adenocarcinoma | Triple Negative Breast Cancer | Epithelial Ovarian Cancer | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal... and other conditionsSpain
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Infinity Pharmaceuticals, Inc.Active, not recruitingAdvanced Solid Tumors (Part A/B/C/D) | Non-small Cell Lung Cancer (Part E) | Melanoma (Part E) | Squamous Cell Cancer of the Head and Neck (Part E) | Triple Negative Breast Cancer (Part F) | Adrenocortical Carcinoma (Part G) | Mesothelioma (Part G) | High-circulating Myeloid-derived Suppressor Cells...United States
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Simcha IL-18, Inc.Merck Sharp & Dohme LLCRecruitingMelanoma | Carcinoma | Renal Cell Carcinoma | Cancer | Solid Tumor | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Triple-negative Breast Cancer | MSI-HighUnited States
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Incyte CorporationMerck Sharp & Dohme LLCCompletedMelanoma | Lymphoma | Head and Neck Cancer | Gastric Cancer | Ovarian Cancer | Hepatocellular Carcinoma (HCC) | Lung Cancer | Bladder Cancer | Endometrial Cancer | Solid Tumors | Renal Cell Carcinoma (RCC) | Triple Negative Breast Cancer (TNBC) | UC (Urothelial Cancer) | Microsatellite-instability (MSI) High Colorectal...United States
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Dana-Farber Cancer InstituteRecruitingMRI | Glioblastoma | Esophageal Cancer | Prostate Cancer | Vulvar Cancer | Magnetic Resonance Imaging | Radiotherapy | Pediatric Glioblastoma MultiformeUnited States
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Shattuck Labs, Inc.Active, not recruitingMelanoma | Renal Cell Carcinoma | Hodgkin Lymphoma | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Diffuse Large B Cell Lymphoma | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Squamous Cell Carcinoma of the Skin | Squamous Cell Carcinoma... and other conditionsUnited States, Canada, Belgium, Spain