Clinical Trials on Machado-Joseph Disease Type 3

Total 53681 results

Memorial Sloan Kettering Cancer Center
Chugai Pharma USA

Recruiting

A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment

Primary Extra-cranial Solid Tumor | Recurrent or Refractory Glypican 3 (GPC3)

United States
Hiantis Srl
Sciensano; Genefirst LTD

Completed

Evaluation of in Vitro Devices on Self-collected Vaginal Swab and Urine Sample for Testing of Human Papilloma Virus (EU-VALHUDES)

Neoplasms | Neoplasms by Histologic Type | Carcinoma in Situ | Neoplasm Cervix | Cervical Intraepithelial Neoplasia Grade 2/3 | Carcinoma Cervix Uterine

Italy, Ireland, United Kingdom
Institut de Recherches Cliniques de Montreal
Canadian Institutes of Health Research (CIHR)

Recruiting

Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

Inflammation | Type 2 Diabetes | Insulin Sensitivity/Resistance | Fatty Acids, Omega-3

Canada
Marco Capogrosso
Roche-Genentech

Recruiting

Spinal Cord Stimulation in Spinal Muscular Atrophy (SCSinSMA)

Spinal Muscular Atrophy Type 3 | Spinal Muscular Atrophy Type 4

United States
Institut de Myologie, France
Institut Roche

Completed

Prospective Study of the Natural History of Patients With Type 2 and 3 Spinal Muscular Atrophy (NatHis-SMA)

Type 2 Spinal Muscular Atrophy | Type 3 Spinal Muscular Atrophy

Belgium, France, Germany
Biruni University

Recruiting

High-dose, Short-term Steroid and Low-dose Long-term Steroid Use in ARDS Caused by COVID-19

Short-term (3 Days) High-dose (1000 mg) Systemic Methylprednisolone

Turkey
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia

Cervical Carcinoma | Cervical Intraepithelial Neoplasia Grade 2/3 | Stage 0 Cervical Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

Astrocytoma, IDH-Mutant, Grade 2 | Astrocytoma, IDH-Mutant, Grade 3

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Frantz Viral Therapeutics

Completed

Intravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3)

Cervical Intraepithelial Neoplasia Grade 2/3 | High-risk HPV (Any Strain)

United States
National Cancer Institute (NCI)

Terminated

Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial Neoplasia

Cervical Cancer | Cervical Intraepithelial Neoplasia Grade 2 | Cervical Intraepithelial Neoplasia Grade 3

United States
Institut National de la Santé Et de la Recherche...

Recruiting

National Cohort on Congenital Defects of the Eye (RaDiCoACOEIL)

Microphthalmia | Aniridia | Anophthalmia | Anterior Segment Dysgenesis 6, Peters Anomaly Subtype | Anterior Segment Dysgenesis 3, Rieger Subtype

France
May Faraj, PDt, PhD
Canadian Institutes of Health Research (CIHR)

Completed

Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry "Bad Cholesterol" in the Blood

Type 2 Diabetes | Inflammatory Response | Insulin Sensitivity/Resistance | Fatty Acids, Omega-3
Hospices Civils de Lyon
Novartis

Completed

Microperimetry and Eye Progressing From Stage 3 to Stage 4 Age-related Macular Degeneration (AMD) (PREVISION)

Stage 3 Age Related Macular Degeneration (AREDS Classification)

France
Fujirebio Diagnostics, Inc.

Completed

Blood Collection From Heart Failure Patients to Evaluate for Galectin-3 Measurement Differences Using Various Collection Tubes

To Measure Galectin-3 in Heart Failure Patients on Commercial Platforms

United States
Astellas Pharma Global Development, Inc.

No longer available

Early Access Program (EAP) of Gilteritinib (ASP2215) in Patients With FMS-like Tyrosine Kinase 3 (FLT3) Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) or With FLT3-Mutated AML in Complete Remission (CR) With Minimal Residual Disease (MRD)

Acute Myeloid Leukemia (AML) | FMS-like Tyrosine Kinase-3 (FLT3) Mutations

Australia, Italy, United Kingdom
West Kazakhstan Medical University

Recruiting

Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan

Ornithine Transcarbamylase Deficiency | Biotinidase Deficiency | Citrullinemia | Glutaric Acidemia Type II | Argininosuccinic Aciduria | Maple Syrup Urine Disease | Primary Carnitine Deficiency | Homocystinuria | Carnitine Palmitoyltransferase II Deficiency | Arginase Deficiency | Very Long-chain Acyl-CoA... and other conditions

Kazakhstan
KemPharm Denmark A/S

Terminated

Study of Arimoclomol in Patients Diagnosed With Gaucher Disease Type 1 or 3

Gaucher Disease, Type 1 | Gaucher Disease, Type 3

India
Tel-Aviv Sourasky Medical Center

Unknown

Long Term Prophylactic Therapy of Congenital Long QT Syndrome Type III (LQT3) With Ranolazine

Long QT Syndrome Type 3

Israel
University of Malaya

Recruiting

Difference of Basal Insulin Titration Method in Reducing HbA1c Among Type 2 Diabetes Mellitus (T2DM) Patients.

to Identify Which Titration Regimen of Basal Insulin (Being Daily Titration vs 3 Daily Titration) is Better in Reducing hba1c and Have Lesser Hypoglycemia

Malaysia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Acalabrutinib, Lenalidomide, and Rituximab for the Treatment of CD20 Positive Stage III-IV, Grade 1-3a Follicular Lymphoma

Grade 3a Follicular Lymphoma | Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann Arbor Stage III Grade 3 Follicular Lymphoma | Ann Arbor Stage...

United States
University Hospital, Bordeaux

Terminated

Prognostic Value of Human Papillomavirus (HPV) Detection in Cervical Intra-epithelial Neoplasia (CIN) Recurrence After Conization (SUIVICOL)

CIN2/3 Recurrence

France
Johns Hopkins University
University of Wisconsin, Madison; Frantz Viral Therapeutics, LLC

Completed

Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3) (ART-AIN)

Precancerous Conditions | Human Papilloma Virus | Anal Dysplasia | HPV-Related Anal Intraepithelial Neoplasia | AIN2/3 | Artesunate | Alternative Treatment

United States
University Hospitals, Leicester

Completed

Effects Of Fish Oil Emulsion On Severe Acute Pancreatitis Patients

Assess Effect of Omega-3 Fish Oil in Patients With Severe Acute Pancreatitis

United Kingdom
Gilead Sciences

Terminated

Effect of Eleclazine on Shortening of the QT Interval, Safety, and Tolerability in Adults With Long QT Syndrome Type 3

Long QT Syndrome Type 3

United States, Germany, Canada, Netherlands, Italy, France, Israel, United Kingdom
National Cancer Institute (NCI)

Active, not recruiting

Ofatumumab and Bendamustine Hydrochloride With or Without Bortezomib in Treating Patients With Untreated Follicular Non-Hodgkin Lymphoma

Grade 3a Follicular Lymphoma | Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann Arbor Stage III Grade 3 Follicular Lymphoma | Ann Arbor Stage...

United States
Yonsei University

Withdrawn

Changes of Keratometric Value and Ocular Aberration After Treatment of Meibomian Gland Dysfunction

Moderate and Severe Meibomiang Gland Dysfunction (Stage 3 or Stage 4 Meibomiang Gland Dysfunction)
Women's Hospital School Of Medicine Zhejiang University
Tongji Hospital; Wuhan Central Hospital

Recruiting

Accurate Screening and Prevention of Cervical Lesions-- Development of Accurate Screening Methods for Cervical Lesions

Cervical Intraepithelial Neoplasia Grade 2/3 | Cervical Lesion

China
Azienda di Servizi alla Persona di Pavia
Abiogen Pharma

Recruiting

Omega 3, Leucine, Probiotic Lactobacillus Paracasei PS23 on Muscle Mass in Sarcopenic Subjects

Sarcopenia | Elderly | Omega 3

Italy
Assiut University

Not yet recruiting

Evaluation of Galectin-3 in Serum and Saliva of Pemphigus Patients

Galectin-3 and Pemphigus
Chang Gung Memorial Hospital

Not yet recruiting

NMDA Enhancement Combined With Omega-3 for Early Dementia

Dementia | Omega 3 Fatty Acids

Taiwan
IRCCS San Camillo, Venezia, Italy
Universita di Verona; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico and other collaborators

Enrolling by invitation

Clinical and Biochemical Features for the Identification of Dominant Calpainopathies (DOM-CAL)

Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A

Italy
Virginia Commonwealth University
University of Colorado, Denver; Washington University School of Medicine; University... and other collaborators

Recruiting

Trial Readiness and Endpoint Assessment in LGMD R1 (GRASP-01-003)

Limb Girdle Muscular Dystrophy | Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A | Limb Girdle Muscular Dystrophy Type R1 | LGMD2A

United States, United Kingdom
Dicerna Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients (PHYOX4)

Primary Hyperoxaluria Type 3

United States, Germany, Netherlands, United Kingdom
Fayoum University

Completed

IL-39 & IL-35 Gingival Crevicular Fluid Levels in Diabetic Patients With Generalized Periodontitis

Generalized Periodontal Disease, AVDC Stage 3

Egypt
Biohaven Pharmaceuticals, Inc.

Active, not recruiting

Trial in Adult Subjects With Spinocerebellar Ataxia

Spinocerebellar Ataxias | Spinocerebellar Ataxia Genotype Type 1 | Spinocerebellar Ataxia Genotype Type 2 | Spinocerebellar Ataxia Genotype Type 3 | Spinocerebellar Ataxia Genotype Type 6 | Spinocerebellar Ataxia Genotype Type 7 | Spinocerebellar Ataxia Genotype Type 8 | Spinocerebellar Ataxia Genotype...

United States
Pharmanutra S.p.a.
NEA Clinical S.r.l.

Completed

LIKEST Study: Lipocet® in Adults With Primary Knee Osteoarthritis Grade 3-4

Primary Knee Osteoarthritis Grade 3 - 4

Georgia
AIO-Studien-gGmbH
Novartis Pharmaceuticals; Assign Data Management and Biostatistics GmbH

Completed

Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study (EVINEC)

Neuroendocrine Carcinoma, Grade 3 | Poorly Differentiated Malignant Neuroendocrine Carcinoma | Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3 | Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma]... and other conditions

Germany
National Cancer Institute (NCI)

Recruiting

Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma

Grade 2 Meningioma | Grade 3 Meningioma | Recurrent Meningioma

United States
Catalyst Pharmaceuticals, Inc.

Terminated

Long Term Safety of Amifampridine Phosphate in Spinal Muscular Atrophy 3 (SMA3)

Spinal Muscular Atrophy Type 3

Italy
The Hong Kong Polytechnic University
The University of Hong Kong; Manchester Metropolitan University

Terminated

Whole Body Vibration Therapy in Children With Spinal Muscular Atrophy

Spinal Muscular Atrophy Type 3

Hong Kong
Northwestern University
Edward Hines Jr. VA Hospital

Terminated

Empowering Veterans to Communicate With Healthcare Providers

Chronic Kidney Disease Stage 3

United States
Rigshospitalet, Denmark

Completed

PACU Discharge Without Motorfunction Assessment After Spinal Anaesthesia

Osteoarthritis Susceptibility 3

Denmark
CANbridge (Suzhou) Bio-pharma Co., Ltd.

Recruiting

Phase 1/2 Study of CAN103 in Subjects With Gaucher Disease

Gaucher Disease, Type 1 | Gaucher Disease, Type 3

China
Concert Pharmaceuticals

Completed

Safety & Tolerability Study of CTP-499 in Patients With Moderate Chronic Kidney Disease

Stage 3 Chronic Kidney Disease

United States
Seoul National University Hospital

Completed

Effect of Phosphate Binders on FGF-23 With Concurrent Calcitriol

Chronic Kidney Disease Stage 3

Korea, Republic of
University of California, Irvine

Terminated

Differences in Immunologic Response to Cryoablation Versus Radiofrequency Ablation in the Treatment of Renal Cell Carcinoma

Immune Response to 3 Approaches
Haukeland University Hospital

Unknown

Switching From Insulin to Sulfonylurea in Diabetes Associated With Variants in MODY Genes (SUtoChildT1D)

Insulin-dependent Diabetes Mellitus | Maturity-Onset Diabetes of the Young, Type 3 | Maturity Onset Diabetes of the Young, Type 1 | Childhood Diabetes Mellitus

Norway
Astellas Pharma Global Development, Inc.

Recruiting

A Study of Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (AML) | Acute Myeloid Leukemia With FMS-like Tyrosine Kinase 3 (FLT3) Mutation / Internal Tandem Duplication (ITD)

United States, Canada, Germany, Italy, Spain, United Kingdom, France
Catharina Ziekenhuis Eindhoven
ZonMw: The Netherlands Organisation for Health Research and Development; Stichting... and other collaborators

Recruiting

Predicting Response In Cervical Intraepithelial Neoplasia to Topical Imiquimod Treatment (PRedICT-TOPIC)

Cervical Intraepithelial Neoplasia | CIN 2/3 | Cervical Intraepithelial Neoplasia Grade 2/3 | Cervical High Grade Squamous Intraepithelial Lesion

Netherlands
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Recruiting

Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function (PHYOX8)

Primary Hyperoxaluria Type 3 | Primary Hyperoxaluria Type 2 | Primary Hyperoxaluria Type 1 | Primary Hyperoxaluria

United States, Canada, Lebanon, Turkey, United Kingdom, Germany, Italy, Japan, Poland, Spain, United Arab Emirates

Clinical Trials on Machado-Joseph Disease Type 3

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