Clinical Trials on Malaria, Cerebral

Total 5385 results

Institute of Tropical Medicine, Belgium
Tropical Diseases Research Centre, Zambia

Terminated

Daily Co-trimoxazole Prophylaxis to Prevent Malaria in Pregnancy

Malaria in Pregnancy

Zambia
Infectious Diseases Research Collaboration, Uganda
London School of Hygiene and Tropical Medicine; Radboud University Medical...

Not yet recruiting

The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy (SPARTAN)

Falciparum; Malaria

Uganda
University of Oxford

Completed

VAC071: A Study to Assess Efficacy of the ChAd63/MVA PvDBP Vaccines

Malaria, Vivax

United Kingdom
University of Oxford
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.; National Institute... and other collaborators

Completed

Study to Compare Feasibility of 1-step Injectable Artesunate vs. Conventional 2-step Injectable Artesunate (1STEP-AS)

Severe Malaria

Congo, The Democratic Republic of the
Centers for Disease Control and Prevention
Evandro Chagas Institute of Clinical Research

Completed

Validation of RealAmp Method for the Diagnosis of Malaria in Endemic Areas of Brazil

Malaria Diagnosis

Brazil
University of California, San Francisco
Centers for Disease Control and Prevention; Uganda Malaria Surveillance Project

Withdrawn

Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda (SP IPTp)

Intermittent Preventive Treatment | Placental Malaria

Uganda
Karolinska Institutet
University of Dschang

Recruiting

Association of Diabetes and Metabolic Syndrome With Severe Malaria in Cameroon

Obesity | Diabetes Mellitus, Type 2 | Metabolic Syndrome | Malaria,Falciparum | Severe Malaria

Cameroon
Menzies School of Health Research
Liverpool School of Tropical Medicine; University of Melbourne; Curtin University and other collaborators

Recruiting

Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy (SAPOT)

Pregnancy Related | Malaria | Malaria in Pregnancy

Papua New Guinea
Kwame Nkrumah University of Science and Technology
Malaria Capacity Development Consortium

Completed

Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana (DHAPPQ/MIP)

Pregnancy Complicated by Malaria as Antepartum Condition

Ghana
National Institute of Malariology, Parasitology...
Institute of Tropical Medicine, Belgium

Unknown

P. Falciparum Resistance to Artemisinin in Vietnam

Drug Resistant Malaria Due to Plasmodium Falciparum

Vietnam
Groupe de Recherche Action en Sante
Institut National de la Santé Et de la Recherche Médicale, France; European...

Active, not recruiting

Follow-up of Immunological Pattern and Pregnancy Outcomes in Women Previously Received Placental Malaria Vaccine (PRIMVACLongT)

Malaria in Pregnancy

Burkina Faso
Liverpool School of Tropical Medicine
Indonesia-MoH; Gadjah Mada University; Yayasan Pengembangan Kesehatan dan Masyarakat...

Completed

Intermittent Preventive Treatment With Dihydroartemisinin-piperaquine in Papua, Indonesia (STOPMiP-2)

Malaria in Pregnancy

Indonesia
National Malaria Control Programme, Madagascar
Sanofi; Population Services International; Institut Pasteur de Madagascar; Reggio... and other collaborators

Completed

ACT for the Home Management in Malagasy Children

Fever | Suspected Malaria

France
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Clinical Decision Support in Non-typhoidal Salmonella Bloodstream Infections in Children (DeNTS)

Bloodstream Infection | Malaria,Falciparum | Severe Malaria | Salmonella Bacteremia

Belgium
University of Kinshasa
Novartis; European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG) (ULTRAPYRAPREG)

Malaria in Pregnancy

Congo, The Democratic Republic of the
Yu Liyun

Unknown

Continous Assessment of Cerebral Autoregulation With Near-infrared Spectroscopy

Cerebral Blood Flow | Cerebral Perfusion Pressure
Medicines for Malaria Venture
GlaxoSmithKline; ICON plc; QIMR Berghofer Medical Research Institute; Swiss BioQuant... and other collaborators

Completed

Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum

Pathologic Processes | Infections | Systemic Inflammatory Response Syndrome | Inflammation | Vector Borne Diseases | Parasitic Diseases | Protozoan Infections | Malaria | Parasitemia | Malaria,Falciparum | Anti-Infective Agents | Antimalarials

Australia
UMC Utrecht

Completed

Parameters of Cerebral Perfusion

Cardiopulmonary Bypass | Cerebral Perfusion | Cerebral Oxygenation

Netherlands
Institut Pasteur
Institut Pasteur de Bangui

Completed

Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum (MACOMBA)

HIV Infection | Malaria in Pregnancy

Central African Republic
Duke University

Completed

Novel mHealth Platform to Ensure Quality of Community-based Malaria Diagnosis

Quality Assurance of Malaria Diagnosis

Kenya
The Mentor Initiative
Ministry of Health, Liberia

Completed

Liberia Insecticide Treated Durable Wall Linings Study: Protocol for a Cluster Randomised Trial (DL)

Anemia | Malaria, Falciparum

Liberia
Centers for Disease Control and Prevention
Ministry of Health and Population, Malawi

Completed

Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: Malawi

HIV Infections | Malaria, Falciparum

Malawi
University of Copenhagen
London School of Hygiene and Tropical Medicine; National Institute for Medical...

Completed

Interactions Between Artemether-lumefantrine and Antiretrovirals in HIV-patients With Uncomplicated Malaria in Tanzania (InterACT)

HIV Infections | Malaria, Falciparum

Tanzania
Ministry of Health and Medical Services, Solomon...
World Health Organization

Terminated

A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands (IPTpRCT)

Malaria | Malaria in Pregnancy

Solomon Islands
Swiss Tropical & Public Health Institute
London School of Hygiene and Tropical Medicine; Hospital Clinic of Barcelona; Ifakara Health Research and Development Centre and other collaborators

Unknown

The Community Effectiveness of IPTi in Southern Tanzania

Anemia | Malaria, Falciparum

Tanzania
University of Oxford
Mahidol University

Not yet recruiting

A Safety, Immunogenicity and Efficacy Study of PvRII/Matrix-M in Healthy Thai Adults Living in Thailand ( MIST3 ) (MIST3)

Plasmodium Vivax Infection | Malaria Vaccine

Thailand
ORIYOMI OMOTOYOSI AKINYOTU
University of Ibadan

Completed

A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients

Malaria in Pregnant HIV + Patients

Nigeria
Institut de Recherche pour le Developpement
Saint Antoine University Hospital; Ministry of Health, Benin; Sidaction; National... and other collaborators

Completed

Prevention of Pregnancy-associated Malaria in HIV-infected Women: Cotrimoxazole Prophylaxis Versus Mefloquine (PACOME)

HIV Infections | Malaria in Pregnancy

Benin
University Health Network, Toronto
University of Toronto; Makerere University

Completed

Inhaled Nitric Oxide for the Adjunctive Therapy of Severe Malaria: a Randomized Controlled Trial

Severe Malaria

Uganda
Institute of Tropical Medicine, Belgium
Tropical Diseases Research Centre, Zambia

Completed

Establishing Effectiveness of Daily Co-trimoxazole Prophylaxis For Prevention of Malaria in Pregnancy

HIV Infections | Malaria in Pregnancy

Zambia
London School of Hygiene and Tropical Medicine
University of Nairobi

Completed

Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education.

Malaria, Falciparum

Kenya
International Rescue Committee
Duke University

Completed

Impact of a Parenting Program in Liberia to Improve Parenting, Education, and Health Outcomes for Children in Liberia

Parenting Behavior | Pre-academic and Developmental Skills | Malaria Prevention

Liberia
Medical Research Council Unit, The Gambia

Completed

Chloroquine and Post Malaria Anaemia Study (CQ-PMA)

Malaria Anaemia
Radboud University Medical Center
Clinical Research Unit of Nanoro

Unknown

Non-specific Effects of Vaccination on Mortality and Morbidity (NOVAC)

Vaccine Reaction | Anemia | Malaria,Falciparum | Salmonella Bacteraemia

Burkina Faso
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)

Malaria Infection

Kenya, Burkina Faso, Gambia, Zambia
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics (INTREPiD)

Pregnancy | Preterm Birth | Gestational Age and Weight Conditions | Malaria in Pregnancy | Stillbirth | Low Birthweight | Malaria,Falciparum | Neonatal Health | Malaria in Childbirth

Congo, The Democratic Republic of the, Kenya
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; University of Copenhagen; University... and other collaborators

Completed

Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa (IMPROVE)

Pregnancy | Malaria | Malaria in Pregnancy

Kenya, Malawi, Tanzania
GlaxoSmithKline
PATH; Iqvia Pty Ltd; AMP (Agence de Médecine Préventive) (in French); RAFT (Réseau... and other collaborators

Completed

A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine

Malaria | Malaria Vaccines

Ghana, Burkina Faso, Kenya
University of Zimbabwe
National Institute of Health Research, Zimbabwe

Completed

Worm Infestation and Child Health in Zimbabwe (Zimworms)

Integrated Control of Malaria and Polyparasitism

Zimbabwe
University of Oxford

Completed

Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam (TACT-CV)

Malaria, Falciparum

Cambodia, Vietnam
London School of Hygiene and Tropical Medicine
DBL -Institute for Health Research and Development

Completed

Relationships Between the Use of Antimalarial Drugs in Pregnancy and Plasmodium Falciparum Resistance

Birth Weight | Malaria in Pregnancy | Anaemia

Burkina Faso
Groupe de Recherche Action en Sante
European Vaccine Initiative

Recruiting

Malaria Burden in Pregnant Women and the Incidence of Pregnancy in a Cohort of Nulligravida (EPI-PAM)

Maternal Malaria During Pregnancy - Baby Not Yet Delivered

Burkina Faso
Noguchi Memorial Institute for Medical Research
Ghana National Malaria Control Programme; Communities

Completed

Determining the Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence in Ghana (DetI-MTTT)

Malaria Asymptomatic Parasitaemia

Ghana
Noguchi Memorial Institute for Medical Research
World Health Organization

Completed

Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children

Malaria | Malaria, Asymptomatic Parasitaemia

Ghana
Foundation for Innovative New Diagnostics, Switzerland
Universidad de Antioquia

Completed

Clinical Performance of the HRP2 HS-RDT for Malaria Diagnosis in Pregnant Women (HSRDT MiP)

Diagnoses Disease | Plasmodium Falciparum | Pregnancy Malaria

Colombia
University of Bamenda
Ministry of Science and Technology of the People´s Republic of China; National...

Completed

Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa

Drug Resistant Malaria Due to Plasmodium Falciparum

Cameroon
Liverpool School of Tropical Medicine
University of Copenhagen; University of Toronto; Centers for Disease Control... and other collaborators

Completed

Improving PRegnancy Outcomes With PReVEntive Therapy in Africa-2 (IMPROVE-2) (IMPROVE-2)

Pregnancy; HIV; Malaria

Kenya
Epicentre
Medecins Sans Frontieres, Spain

Withdrawn

Efficacy of Artesunate-amodiaquine (AS-AQ) in Children With Malaria and Severe Acute Malnutrition, Madaoua, Niger 2010

Child | Malnutrition | Malaria, Falciparum

Niger
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE) (EPiTOMISE)

Malaria,Falciparum

Kenya
Centre de Recherche Médicale de Lambaréné
Institute of Tropical Medicine, University of Tuebingen

Not yet recruiting

A Crossover Bioavailability Clinical Trial of Parenteral Pyronaridine and Artesunate

Severe Malarial Treatment

Gabon

Clinical Trials on Malaria, Cerebral

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