Continous Assessment of Cerebral Autoregulation With Near-infrared Spectroscopy

November 15, 2016 updated by: Yu Liyun
Cerebral autoregulation can be explained by a tight coupling between oxygen supply and demand of the brain, and is essential to maintain a constant cerebral blood flow (CBF) in the context of changes in cerebral perfusion pressure. In this study, investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation.

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Detailed Description

Near-infrared spectroscopy (NIRS) is a noninvasive technology that real-time monitors cerebral tissue oxygenation index (TOI). Investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation of hypertensive participants and non-hypertensive participants.

Study Type

Observational

Enrollment (Anticipated)

40

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

  1. adult
  2. health people
  3. people with hypertension

Description

Inclusion Criteria:

  • health people, or people with hypertension

Exclusion Criteria:

  • diabetes, anemia, liver disease, kidney disease.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
normal
Human without hypertension, diabetes, anemia, liver disease and kidney disease. The group will measure TOI and BP.
Device: measure TOI and BP
Both groups measure TOI and BP.
hypertension

Human only have hypertension, without diabetes, anemia, liver disease and kidney disease.

Hypertension group will measure TOI and BP.
Device: measure TOI and BP
Both groups measure TOI and BP.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
range of cerebral autoregulation
Time Frame: 30min
30min

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Yu Liyun

Investigators

  • Principal Investigator: Xiaohong Wu, Beijing Electric Power Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

December 1, 2016

Primary Completion (Anticipated)

December 1, 2018

Study Completion (Anticipated)

December 1, 2019

Study Registration Dates

First Submitted

November 5, 2016

First Submitted That Met QC Criteria

November 5, 2016

First Posted (Estimate)

November 8, 2016

Study Record Updates

Last Update Posted (Estimate)

November 16, 2016

Last Update Submitted That Met QC Criteria

November 15, 2016

Last Verified

November 1, 2016

More Information

Terms related to this study

Other Study ID Numbers

  • 111

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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Locations

3
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