Clinical Trials on Malignant Oral Cavity Neoplasm

Total 5069 results

University of Washington
Blaze Bioscience Inc.

Recruiting

A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery

Stage III Lip and Oral Cavity Cancer AJCC v8 | Oral Cavity Squamous Cell Carcinoma | Stage I Lip and Oral Cavity Cancer AJCC v8 | Stage II Lip and Oral Cavity Cancer AJCC v8 | Stage IVA Lip and Oral Cavity Cancer AJCC v8

United States
Ohio State University Comprehensive Cancer Center

Completed

Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental Care

Tongue Cancer | Lip and Oral Cavity Squamous Cell Carcinoma | Oral Cavity Verrucous Carcinoma | Stage 0 Lip and Oral Cavity Cancer

United States
Dow University of Health Sciences

Completed

Behavior Changing Intervention for Smokeless Tobacco and Betel Quid Use in Adolescents

Oral Cavity Carcinoma

Pakistan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

Osteoradionecrosis | Malignant Skull Base Neoplasm | Malignant Oral Cavity Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab in Treating Patients With High Risk Oral Intraepithelial Neoplasia

Oral Cavity Carcinoma | Oral Intraepithelial Neoplasia

United States
Medical University of South Carolina
Bristol-Myers Squibb

Completed

Trial of Nivolumab as a Novel Neoadjuvant Pre-Surgical Therapy for Locally Advanced Oral Cavity Cancer

Oral Cavity SCC

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Photodynamic Therapy With HPPH in Treating Patients With Squamous Cell Carcinoma of the Oral Cavity

Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Verrucous Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Oropharynx | Stage I Verrucous... and other conditions

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Withdrawn

Hypofractionated Radiation Therapy Followed by Surgery in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity

Tongue Cancer | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Verrucous Carcinoma of the Oral Cavity | Stage IVA Verrucous Carcinoma of the Oral Cavity | Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVB Verrucous Carcinoma of the Oral Cavity | Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity

United States
University Hospital, Basel, Switzerland

Recruiting

Reinnervated PAP Flap for Oral Cavity and Oropharyngeal Defect Reconstruction

Oral Cavity Defect | Oropharynx Defect

Switzerland
Ohio State University Comprehensive Cancer Center

Recruiting

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

Tongue Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Verrucous Carcinoma of the Larynx | Recurrent Verrucous Carcinoma of the Oral Cavity | Recurrent Adenoid... and other conditions

United States
National Cancer Institute (NCI)

Completed

Gene Therapy in Preventing Cancer in Patients With Premalignant Carcinoma of the Oral Cavity or Pharynx

Lip and Oral Cavity Cancer | Oropharyngeal Cancer | Tongue Cancer | Stage 0 Lip and Oral Cavity Cancer | Stage 0 Oropharyngeal Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Cutaneous Melanoma | Recurrent Malignant Female Reproductive System Neoplasm | Refractory Malignant Female Reproductive System Neoplasm | Recurrent Lip and Oral Cavity Carcinoma | Recurrent Malignant Endocrine... and other conditions

United States
National Cancer Institute (NCI)

Completed

Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Patients With Oral Leukoplakia

Lip and Oral Cavity Cancer | Oropharyngeal Cancer | Tongue Cancer | Oral Leukoplakia

United States
Centre Hospitalier Universitaire Dijon

Completed

Spectrometry of Cancerous Lesions of the Oral Cavity (SpectrORL1)

Cancerous Lesions of the Oral Cavity

France
Ohio State University Comprehensive Cancer Center

Completed

Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral Cancer Survivors

Tongue Cancer | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Oropharynx | Stage I Verrucous Carcinoma of the Oral Cavity | Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage II Squamous Cell Carcinoma of the Oropharynx | Stage... and other conditions

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck Lesions

Precancerous Condition | Lip and Oral Cavity Squamous Cell Carcinoma | Oral Cavity Verrucous Carcinoma

United States
Shanghai Jiao Tong University School of Medicine

Completed

TPF Induction Chemotherapy for Locally Advanced and Resectable Oral Squamous Cell Carcinoma

Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage III Oral Cavity Squamous Cell Carcinoma

China
Wake Forest University Health Sciences

Terminated

Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer Who Are Undergoing Radiation Therapy and/or Chemotherapy

Stage I Adenoid Cystic Carcinoma of the Oral Cavity | Stage I Mucoepidermoid Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Hypopharynx | Stage I Squamous Cell Carcinoma of the Larynx | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Verrucous Carcinoma... and other conditions

United States
Alpha Tau Medical LTD.

Recruiting

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal and Superficial Soft Tissue Neoplasia (DaRT)

Skin Cancer | Mucosal Neoplasm of Oral Cavity | Soft Tissue Neoplasm

Italy
Alpha Tau Medical LTD.

Active, not recruiting

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT)

Skin Cancer | Mucosal Neoplasm of Oral Cavity | Soft Tissue Neoplasm

Israel
National Cancer Institute (NCI)

Terminated

ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment

Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage III Oral Cavity Squamous Cell Carcinoma... and other conditions

United States
Alpha Tau Medical LTD.

Recruiting

Retreatment With Intratumoral Diffusing Alpha Radiation Emitters

Skin Cancer | Mucosal Neoplasm of Oral Cavity | Soft Tissue Neoplasm

Israel
Alpha Tau Medical LTD.

Recruiting

Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia

Skin Cancer | Mucosal Neoplasm of Oral Cavity | Soft Tissue Neoplasm

Israel
Alpha Tau Medical LTD.

Recruiting

Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.

Skin Cancer | Mucosal Neoplasm of Oral Cavity | Soft Tissue Neoplasm

Israel
Emory University
Bristol-Myers Squibb; Brooklyn ImmunoTherapeutics, LLC

Withdrawn

Nivolumab & IRX-2 With Surgery for Resectable Stage III-IVA Oral Cavity Cancer or HPV-Positive Oropharyngeal Cancer

Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma | Stage II Oral Cavity Squamous Cell...

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer

Stage I Oral Cavity Squamous Cell Carcinoma | Stage II Oral Cavity Squamous Cell Carcinoma

United States
Mitchell Machtay

Not yet recruiting

A Window of Opportunity Study of Black Raspberry for Patients With HNSCC

Squamous Cell Carcinoma of the Oral Cavity or Oropharynx
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Preoperative TPF Chemotherapy in Molecularly Selected Locally Advanced Resectable Oral Cavity Squamous Cell Cancer

Locally Advanced Resectable Oral Cavity Squamous Cell Cancer

Italy
Sichuan University

Recruiting

Dual-targeting VEGFR1 and PD-L1 CAR-T for Cancers Patients With Pleural or Peritoneal Metastases

Malignant Ascites | Malignant Peritoneal Effusion | Serous Cavity Metastatises

China
National Cancer Institute (NCI)

Completed

Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Laryngeal Verrucous Carcinoma | Recurrent Oral Cavity Verrucous Carcinoma | Tongue... and other conditions

United States
National Cancer Institute (NCI)
Dana-Farber Cancer Institute

Withdrawn

ONYX-015 With Cisplatin and Fluorouracil in Treating Patients With Advanced Head and Neck Cancer

Head and Neck Cancer | Lip and Oral Cavity Cancer | Oropharyngeal Cancer

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Phase I/II Study of Postoperative Adjuvant Chemoradiation for Advanced-Stage Cutaneous Squamous Cell Carcinoma of the Head and Neck (cSCCHN)

Squamous Cell Carcinoma of the Skin | Recurrent Skin Cancer | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVA Squamous Cell Carcinoma of the...

United States
National Health Research Institutes, Taiwan
National Taiwan University Hospital; Mackay Memorial Hospital; China Medical... and other collaborators

Completed

Post-Operative Adjuvant Concurrent Chemoradiotherapy For High Risk Oral Cavity Squamous Cell Carcinoma Patients

Squamous Cell Carcinoma | Oral Cavity

Taiwan
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer

Human Papillomavirus Infection | Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage IVA Oropharyngeal Squamous Cell Carcinoma | Stage IVB Oropharyngeal Squamous Cell Carcinoma | Stage IVC Oropharyngeal Squamous Cell Carcinoma | Stage I Oropharyngeal Squamous Cell Carcinoma | Stage II Oropharyngeal... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Multimodal Imaging for Surveillance in Patients With Oral Potentially Malignant Disorders

Dysplasia | Premalignant Lesion | Lip and Oral Cavity Carcinoma | Oral Disorder

United States
M.D. Anderson Cancer Center

Active, not recruiting

Dyadic Yoga Intervention for Patient With Head and Neck Cancer Undergoing Radiotherapy and Their Family Caregivers

Head and Neck Cancer | Malignant Neoplasms of Lip Oral Cavity and Pharynx

United States
University of British Columbia

Recruiting

Mandibular Reconstruction Preplanning (ViPMR) (ViPMR)

Oral Cancer | Oral Cavity Cancer

Canada
M.D. Anderson Cancer Center

Recruiting

Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

Head and Neck Carcinoma | Nasal Cavity Carcinoma | Oral Cavity Carcinoma | Tongue Carcinoma | Maxillary Sinus Carcinoma | Malignant Parotid Gland Neoplasm | Tonsillar Carcinoma

United States
National Health Research Institutes, Taiwan
National Taiwan University Hospital; Mackay Memorial Hospital; China Medical... and other collaborators

Completed

Chemoprevention Study of Oral Cavity Squamous Cell Carcinoma

Squamous Cell Carcinoma | Oral Cavity

Taiwan
Shenzhen SiBiono GeneTech Co.,Ltd

Unknown

rAd-p53 Gene Therapy for Advanced Oral and Maxillofacial Malignant Tumors (rAd-p53)

Advanced Oral and Maxillofacial Malignant Tumors

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Wide-Field and High Resolution In Vivo Imaging in Visualizing Lesions in Patients With Oral Neoplasia Undergoing Surgery

Oral Cavity Neoplasm

United States
Memorial Sloan Kettering Cancer Center
Monash University

Completed

Quality of Life and Development of Measures in Patients With Cancer of the Oral Cavity

Cancer of the Oral Cavity

United States
University of Chicago
Stand Up To Cancer

Recruiting

Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials

Cancer | Malignant Neoplasm | Malignancy

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

Oral Cavity Squamous Cell Carcinoma | Stage I Lip and Oral Cavity Cancer AJCC v8 | Stage II Lip and Oral Cavity Cancer AJCC v8 | Buccal Mucosa Squamous Cell Carcinoma | Floor of Mouth Squamous Cell Carcinoma | Gingival Squamous Cell Carcinoma | Hard Palate Squamous Cell Carcinoma | Lip Squamous Cell... and other conditions

United States, Canada
National Cancer Institute (NCI)

Terminated

Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Laryngeal Verrucous Carcinoma | Recurrent Metastatic Squamous Cell Carcinoma in... and other conditions

Canada
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma and other conditions

United States
University Health Network, Toronto

Completed

A Comparative Study of Ultrasound Versus CT Measurement of Tongue and Oral Cavity Size

Ultrasound Airway Imaging in Determining the Oral Cavity and Tongue Size

Canada
Medical College of Wisconsin

Not yet recruiting

Antitumor-B KAC PK Study

Squamous Cell Carcinoma of the Oral Cavity

United States
Abdulsalam Alqutub

Completed

Oral Cavity Squamous Cell Carcinoma and Readmission: Rates, Causes, and Risk Factors.

Oral Cavity Squamous Cell Carcinoma; Readmission

Saudi Arabia
Universitaire Ziekenhuizen KU Leuven
AstraZeneca; European Organisation for Research and Treatment of Cancer - EORTC and other collaborators

Active, not recruiting

Durvalumab With or Without Tremelimumab in Resectable Locally Advanced Squamous Cell Carcinoma of the Oral Cavity (DUTRELASCO)

Oral Cavity Squamous Cell Carcinoma

Belgium

Clinical Trials on Malignant Oral Cavity Neoplasm

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