Clinical Trials on Malignant Germ Cell Neoplasm

Total 32227 results

NewLink Genetics Corporation

Completed

Vaccine Treatment for Advanced Malignant Melanoma

Malignant Melanoma

United States
Merck Sharp & Dohme LLC

Completed

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Participants With Advanced Melanoma (MK-3475-002/P08719/KEYNOTE-002)

Malignant Melanoma
Acrotech Biopharma Inc.

Completed

Pharmacokinetic Study of Liposomal Vincristine in Patients With Malignant Melanoma & Hepatic Dysfunction

Malignant Melanoma

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Definition of an Immune Signature Predictive of Anti-PD1 (Programmed Death-1) Antibody in the Treatment of Advanced Melanoma (PREDIMEL)

Malignant Melanoma
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial

Meningioma | Low Grade Glioma | Malignant Brain Neoplasm | Malignant Brain Glioma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Targeted Imaging of Glutamate Carboxypeptidase II With DCFPyL-PET

Malignant Tumors | Schwannomas

United States
Molecular Insight Pharmaceuticals, Inc.

Withdrawn

Study to Evaluate the Efficacy and Safety of 90Y-SMT487 in Subjects With Symptomatic Malignant Carcinoid Tumors

Malignant Carcinoid Tumor
St. Louis University

Completed

Neoadjuvant Pembrolizumab for Unresectable Stage III and Unresectable Stage IV Melanoma (NeoPembroMel)

Melanoma | Metastatic Melanoma | Stage IV Melanoma | Unresectable Malignant Neoplasm | Stage III Melanoma

United States
British Columbia Cancer Agency
Canadian Urologic Oncology Group; German Testicular Cancer Study Group; NCIC...

Completed

Phase-II Study of SU011248 (Sunitinib)in Male Patients With Relapsed or Cisplatin-Refractory Germ Cell Cancer

Relapsed or Cisplatin-Refractory Germ Cell Cancer

Canada
Singapore General Hospital
National Cancer Centre, Singapore; National Neuroscience Institute Singapore; Duke-NUS Centre of Quantitative Medicine and other collaborators

Not yet recruiting

FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma (FET PET in HGG)

Glioma, Malignant
Darell Bigner
Rockefeller University

Recruiting

Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

Glioma, Malignant

United States
National Cancer Institute (NCI)

Active, not recruiting

Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma

United States, Canada, Puerto Rico, Australia, New Zealand
University of Michigan Rogel Cancer Center
Phase One Foundation

Completed

Combined Cytotoxic and Immune-Stimulatory Therapy for Glioma

Glioblastoma Multiforme | Malignant Glioma

United States
AbbVie

Completed

Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma

Japan
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Adherence Monitoring System in Managing Myelosuppression in Patients With Newly Diagnosed Malignant Gliomas Receiving Temozolomide and Radiation Therapy

Malignant Glioma | Myelosuppression

United States
Frank Lieberman
Oncovir, Inc.

Completed

Vaccination-Dendritic Cells With Peptides for Recurrent Malignant Gliomas

Malignant Glioma

United States
Dana-Farber Cancer Institute
Memorial Sloan Kettering Cancer Center; Massachusetts General Hospital; University... and other collaborators

Withdrawn

MK-2206 for Recurrent Malignant Glioma

Malignant Glioma

United States
Duke University
Genentech, Inc.

Completed

Radiosurgery and Avastin for Recurrent Malignant Gliomas

Malignant Glioma

United States
H. Lee Moffitt Cancer Center and Research Institute
Cephalon

Terminated

Nuvigil or Placebo in Newly Diagnosed Malignant Glioma

Malignant Glioma

United States
Candel Therapeutics, Inc.

Completed

Phase 1b Study of AdV-tk + Valacyclovir Combined With Radiation Therapy for Malignant Gliomas (BrTK01)

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma

United States
Jonsson Comprehensive Cancer Center
United States Department of Defense

Recruiting

Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma

Glioma | Malignant Glioma | Recurrent Malignant Glioma | Recurrent Glioma

United States
Chang Gung Memorial Hospital

Completed

Early-Phase Safety of Proton Therapy Equipment

Hepatocellular Carcinoma | Prostate Cancer | Malignant Glioma | Head and Neck Malignant Tumor

Taiwan
National Cancer Institute (NCI)

Completed

Arsenic Trioxide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Southwest... and other collaborators

Completed

Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors

Testicular Germ Cell Tumor | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States, Puerto Rico, Australia, Peru
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Skin Squamous Cell Carcinoma | Unresectable Solid Neoplasm | Metastatic Kidney Medullary Carcinoma | Metastatic Penile Carcinoma | Small Cell Carcinoma | Metastatic Adrenal Gland Pheochromocytoma | Stage IV Penile Cancer... and other conditions

United States
Ahmad Tarhini
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Intraocular Melanoma | Malignant Conjunctival Neoplasm | Melanoma (Skin)

United States
UNICANCER

Terminated

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell Tumors

Testicular Germ Cell Tumor | Ovarian Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Cutaneous Melanoma | Recurrent Malignant Female Reproductive System Neoplasm | Refractory Malignant Female Reproductive System Neoplasm | Recurrent Lip and Oral Cavity Carcinoma | Recurrent Malignant Endocrine... and other conditions

United States
European Organisation for Research and Treatment...

Completed

MEN-10755 in Treating Patients With Solid Tumors

Testicular Germ Cell Tumor | Unspecified Adult Solid Tumor, Protocol Specific

France, Netherlands, Norway, Belgium, Switzerland, Austria, United Kingdom, Germany, Denmark
European Institute of Oncology
Merck Sharp & Dohme LLC

Recruiting

ECT-Pembrolizumab in Patients With Unresectable Melanoma With Superficial or Superficial and Visceral Metastases

Malignant Melanoma

Italy
University Hospital Muenster

Unknown

Anesthesia and Cancer Recurrence im Malignant Melanoma

Malignant Melanoma

Germany
University Hospital Freiburg
Universitätsklinikum Köln; Essex Pharma GmbH

Unknown

Quality of Life and Psychological Well-being in Patients With Malignant Melanoma

Malignant Melanoma

Germany
National Cancer Institute (NCI)

Active, not recruiting

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

Malignant Glioma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent... and other conditions

United States, Puerto Rico
TransMolecular

Terminated

A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma

Melanoma | Metastatic Melanoma | Malignant Melanoma

United States
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Not yet recruiting

Photodynamic Diagnosis for Malignant Brain Glioma With 5-Aminolevulinic Acid（5-ALA）

Malignant Glioma of Brain | 5-aminolevulinic Acid

China
Duke University
Pfizer

Completed

Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide

Glioblastoma

United States
Oxford University Hospitals NHS Trust
Baxter Healthcare Corporation

Completed

Post-Operative Drainage Following Lymph Node Dissection

Carcinoma, Squamous Cell | Malignant Melanoma
Abramson Cancer Center of the University of Pennsylvania
United States Department of Defense

Completed

Skull Base and Low Grade Glioma Neurocognitive Magnetic Resonance Imaging (MRI) Study

Glioma | Radiotherapy | Malignancy

United States
National Cancer Institute (NCI)

Terminated

Lapatinib in Stage IV Melanoma With ERBB4 Mutations

Malignant Melanoma

United States
Dana-Farber Cancer Institute
Massachusetts General Hospital; Pfizer; Beth Israel Deaconess Medical Center

Completed

SU011248 in Patients With Metastatic Mucosal or Acral/Lentiginous Melanoma

Mucosal Lentiginous Melanoma | Acral Lentiginous Malignant Melanoma

United States
Morphotek

Terminated

A Safety and MORAb-028 Dose Determination Study in Subjects With Metastatic Melanoma

Melanoma | Metastatic Melanoma | Advanced Melanoma | Malignant Metastatic Melanoma

United States
Centre Hospitalier Universitaire de Besancon

Unknown

Study Evaluating the Impact of Short Message Service on Compliance With Surveillance of Patients With Germ-cell Tumors (TEXTIS)

Compliance, Patient | Germ Cell Tumor | Follow-up | Text Messaging

France
Indiana University School of Medicine
AstraZeneca

Terminated

A Phase II Study of Iressa in Patients With Chemo Refractory Germ Cell Tumors Expressing EGFR (IUCRO-0021)

Refractory Germ Cell Tumors Expressing EGRF

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
UNICANCER

Completed

Combination Chemotherapy With Bone Marrow Transplantation in Treating Men With Germ Cell Tumors

Testicular Germ Cell Tumor | Extragonadal Germ Cell Tumor

France
University Hospital, Bonn
Mundipharma Research GmbH & Co KG

Terminated

A Clinical Trial to Assess the Safety & Efficacy of the Treatment of Patients With Metastasis From Malignant Melanoma - Treatment Consists of the Substances Lomustine (Capsules) & Cytarabine (Injected Into an Area Near the Spinal Cord), Accompanied by Radiotherapy of the Brain

Leptomeningeal Metastasis From Malignant Melanoma

Germany
Heinrich-Heine University, Duesseldorf

Unknown

Trial to Evaluate Progression Free Survival With Primary Retroperitoneal Lymph-node Dissection (pRPLND) Only in Patients With Seminomatous Testicular Germ Cell Tumors With Clinical Stage IIA/B (PRIMETEST)

Stage II A/B Seminomatous Germ Cell Tumors

Germany
Tactical Therapeutics, Inc.

Active, not recruiting

Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas

Solid Tumors, Glioblastoma, Recurrent Malignant Gliomas

United States
Amgen

Completed

AMG 595 First-in-Human in Recurrent Gliomas

Glioblastoma Multiforme | Advanced Malignant Glioma | Anaplastic Astrocytomas

United States, Australia
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC; Celgene

Active, not recruiting

Study of Oral Azacitidine (CC-486) in Combination With Pembrolizumab (MK-3475) in Patients With Metastatic Melanoma

Metastatic Melanoma | Melanoma and Other Malignant Neoplasms of Skin

United States

Clinical Trials on Malignant Germ Cell Neoplasm

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