Clinical Trials on Malignant Germ Cell Tumor

Total 10224 results

Ira Winer

Recruiting

ASk Questions in GYnecologic Oncology (ASQ-GYO) (ASQ-GYO)

Cervical Cancer | Ovarian Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Gestational Trophoblastic Disease

United States
Pfizer

Withdrawn

Study of PF-07224826, as a Single Agent or in Combination With Endocrine Therapy in Participants With Breast Cancer and Other Advanced Solid Tumors.

Breast Cancer | Ovarian Cancer | Non-small Cell Lung Cancer (NSCLC) | Solid Tumors | Liposarcoma | Endometrial
University Health Network, Toronto
Novartis; Mount Sinai Hospital, Canada; Princess Margaret Hospital, Canada

Terminated

Chromosome Abnormalities in Chronic Myeloid Leukemia (CML) on Imatinib. GIST Patients on Imatinib (GIST)

Chronic Myeloid Leukemia | Chromosome Abnormality | Gastrointestinal Stromal Cell Tumors

Canada
National Cancer Institute (NCI)

Recruiting

Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)

Pathologic Processes | Infections | Neoplasms | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases | Neoplasms by Histologic Type | Neoplasms, Glandular and Epithelial | Recurrence | Disease Attributes | Papilloma | DNA Virus Infections | Papillomavirus Infections | Tumor Virus Infections | Neoplasms...

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia

Untreated Childhood Acute Lymphoblastic Leukemia | Childhood T Acute Lymphoblastic Leukemia | Neurotoxicity Syndrome | Childhood B Acute Lymphoblastic Leukemia | Cognitive Side Effects of Cancer Therapy | Psychological Impact of Cancer | Long-Term Effects Secondary to Cancer Therapy in Children

United States, Canada, Australia, New Zealand
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Primary Peritoneal Carcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Malignant Ovarian Endometrioid Tumor | Ovarian High Grade Serous Adenocarcinoma | Platinum-Sensitive Ovarian Carcinoma | Fallopian Tube High Grade Serous Adenocarcinoma and other conditions

United States
GI Cell, Inc.

Recruiting

A Study of GIC-102 (Allogeneic Natural Killer Cells) in Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, and Multiple Myeloma

Advanced Solid Tumors | Relapsed/Refractory Multiple Myeloma | Relapsed/Refractory Non-Hodgkin Lymphoma

Korea, Republic of
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Official Record of Patients Diagnosed With Lymphangioleiomyomatosis (LAM)

Leiomyomatosis

United States
Huazhong University of Science and Technology
Guangxi Medical University; Peking University People's Hospital; First Affiliated... and other collaborators

Unknown

Clinical Database and Biobank of Patients With Gynecologic Neoplasms

Cervical Cancer | Endometriosis | Ovarian Cancer | Endometrial Cancer | Choriocarcinoma | Uterine Myoma

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes

Stage IV Prostate Cancer AJCC v8 | Hepatobiliary Neoplasm | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Malignant Neoplasm and other conditions

United States
National Cancer Institute (NCI)

Withdrawn

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Cervical Carcinoma | Recurrent Melanoma | Vaginal Carcinoma | Esophageal Carcinoma | Mucosal Melanoma | Mucosal Melanoma of the Head and Neck | Oral Cavity Mucosal Melanoma | Stage II Vulvar Cancer AJCC v7 | Stage III Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 and other conditions

United States
Ikena Oncology
Gilead Sciences

Terminated

A Study of PY314 in Subjects With Advanced Solid Tumors

Renal Cell Carcinoma | Breast Cancer | Gynecologic Cancer | Colorectal Cancer | Ovarian Cancer | Lung Adenocarcinoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Hormone Receptor/Growth Factor Receptor-Negative Breast Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant

Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Malignant Neoplasm | Bacterial Infection | Myeloid Neoplasm | Benign Neoplasm | Methicillin-Resistant Staphylococcus Aureus Infection

United States, Canada, Puerto Rico
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases

Asthma | Pulmonary Fibrosis | Lymphangioleiomyomatosis | Pulmonary Disease | Sarcoidosis | Oropharyngeal Disease

United States
University Hospital Ostrava

Completed

Recurrent Respiratory Papillomatosis and Extraesophageal Reflux

Recurrent Respiratory Papillomatosis | Extra Oesophageal Reflux | Laryngeal Cyst

Czechia
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Preventing Cervical Cancer in Patients With Cervical Intraepithelial Neoplasia

Cervical Cancer | Human Papilloma Virus Infection | Cervical Intraepithelial Neoplasia Grade 3

United States
University of Michigan Rogel Cancer Center

Completed

Study of High-Dose Chemotherapy With Bone Marrow or Stem Cell Transplant for Rare Poor-Prognosis Cancers

Nasopharyngeal Cancer | Fibrosarcoma | Wilms Tumor | Brain Tumor, Recurrent | Carcinoma, Round Cell

United States
MedSIR
Daiichi Sankyo

Recruiting

HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease (TUXEDO-3)

Metastatic Breast Cancer | Solid Tumor, Adult | Advanced Non-Small Cell Squamous Lung Cancer

Spain, Austria
Famewave Ltd.
Bristol-Myers Squibb

Active, not recruiting

A Study of CM24 in Combination With Nivolumab in Adults With Advanced Solid Tumors

Melanoma | Pancreatic Cancer | Ovarian Cancer | Solid Tumor | Non Small Cell Lung Cancer | Colorectal Adenocarcinoma | Papillary Thyroid Cancer

Spain, United States, Israel
Hospital Universitari de Bellvitge
Institut d'Investigació Biomèdica de Bellvitge

Unknown

E6/E7 mRNA Performance to Detect HSIL and Cost-effectiveness Analysis of This Screening Strategy in HIV + MSM (ELAVI-67)

Hiv | Anal Cancer | HPV - Anogenital Human Papilloma Virus Infection | HSIL, High Grade Squamous Intraepithelial Lesions

Spain
National Cancer Institute (NCI)

Completed

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Secondary Acute Myeloid Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Acute Undifferentiated Leukemia

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Young Melanoma Family Facebook Intervention or Healthy Lifestyle Facebook Intervention in Improving Skin Examination in Participants With Melanoma and Their Families

Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Clinical Stage 0 Cutaneous Melanoma AJCC v8 | Clinical Stage I Cutaneous Melanoma AJCC v8 | Clinical Stage IA Cutaneous Melanoma AJCC v8 | Clinical... and other conditions

United States
ProfoundBio US Co.

Recruiting

PRO1184 for Advanced Solid Tumors (PRO1184-001)

Ovarian Cancer | Fallopian Tube Cancer | Mesothelioma | Triple Negative Breast Cancer | Endometrial Cancer | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Breast Adenocarcinoma | High Grade Epithelial Ovarian Cancer | Hormone Receptor-positive/Her2 Negative Breast Cancer

United States, China
Riphah International University

Completed

Incentive Spirometry and Upper Abdominal Laparoscopic Surgery

Hiatal Hernia | Cholecystitis | Choledocholithiasis | Splenomegaly | Diaphragmatic Hernia | Perforated Duodenal Ulcer | Malignant Pancreatic Neoplasm | Benign Pancreas Tumor | Splenic Infarction

Pakistan
PureTech

Recruiting

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Solid Tumor | Metastatic Cancer | Urothelial Carcinoma

United States
Centre Hospitalier Universitaire Dijon

Completed

Quantitative and Functional Study of TH17 Lymphocytes in Horton's Disease (HD)

Infectious Disease | Solid Tumor | Hemopathy | Horton's Disease | Neoplasia

France
National Cancer Institute (NCI)

Completed

Green Tea Extract in Preventing Cervical Cancer in Patients With Human Papillomavirus and Low-Grade Cervical Intraepithelial Neoplasia

Cervical Cancer | Human Papilloma Virus Infection | Cervical Intraepithelial Neoplasia Grade 1

United States
Novartis Pharmaceuticals

Completed

Study to Allow Access to Nilotinib for Patients Who Are on Nilotinib Treatment in a Novartis-sponsored Study

Acute Lymphoblastic Leukemia (ALL) | Chronic Myelogenous Leukemia (CML) | Metastatic Gastrointestinal Stromal Tumors (GIST) | Receptor Tyrosine Kinase (KIT) Mutated Melanoma

Italy, United Kingdom, Canada, Singapore, Netherlands, France, Korea, Republic of, United States, Slovakia, Hungary, Russian Federation, Hong Kong, Spain, Israel, Sweden, Austria
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Warm Ischemia or Cold Ischemia During Surgery in Treating Patients With Stage I Kidney Cancer

Kidney Cancer | Perioperative/Postoperative Complications | Urinary Complications | Long-term Effects Secondary to Cancer Therapy in Adults

United States
Celldex Therapeutics

Completed

A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies

Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Cholangiocarcinoma | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Hepatic Cancer | Bladder Urothelial Carcinoma | Other Solid Tumors | MSI-H Colorectal Cancer

United States
Theratechnologies
PPD; Syneos Health; Windtree Therapeutics; Innovaderm Research Inc.; Altasciences...

Recruiting

TH1902 in Patients With Advanced Solid Tumors

Solid Tumor | Prostate Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | Small-cell Lung Cancer | Thyroid Cancer | Cutaneous Melanoma | TNBC - Triple-Negative Breast Cancer | Hormone Receptor-positive Breast Cancer | SORT1+ Cancers

United States, Canada
Mayo Clinic
National Cancer Institute (NCI)

Completed

Pharmacogenomics Testing in Directing the Optimal Use of Supportive Care Medications in Patients With Stage III-IV Cancer

Malignant Solid Neoplasm | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma | Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation | Endometrioid Stromal Sarcoma

United States
Masonic Cancer Center, University of Minnesota

Terminated

Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases

Chronic Myelogenous Leukemia | Acute Leukemias | Burkitt's Lymphoma

United States
Masonic Cancer Center, University of Minnesota

Recruiting

Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

Sickle Cell Disease | Severe Congenital Neutropenia | Paroxysmal Nocturnal Hemoglobinuria | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Diamond Blackfan Anemia | Transfusion Dependent Alpha- or Beta- Thalassemia | Non-Malignant Hematologic Disorders

United States
Genmab

Completed

Enapotamab Vedotin (HuMax-AXL-ADC) Safety Study in Patients With Solid Tumors

Melanoma | Sarcoma | Cervical Cancer | Ovarian Cancer | Endometrial Cancer | Solid Tumors | Thyroid Cancer | Non Small Cell Lung Cancer (NSCLC)

United States, United Kingdom, Belgium, Denmark, Netherlands, Spain
Antiva Biosciences

Terminated

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | HSIL, High-Grade Squamous Intraepithelial Lesions | Anus Neoplasm

United States, Australia
Southwest Oncology Group
National Cancer Institute (NCI); Novartis

Completed

S0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone Metastases

Breast Cancer | Multiple Myeloma | Lung Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Plasma Cell Neoplasm

United States, Mexico, Saudi Arabia
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

HIV Infection | Anal Cancer | Anus Neoplasms | Human Papilloma Virus Infection | HSIL, High-Grade Squamous Intraepithelial Lesions

United States, Australia
Vivent Health
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

The Prevalence of Oral HPV Infection and Oral Lesions in People Living With HIV (SWISH)

Human Immunodeficiency Virus | Human Papilloma Virus

United States
Dr Jean Yannis PERENTES

Recruiting

Treatment Pleural Carcinosis of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin Administration (PITHAC)

Carcinoma, Non-Small-Cell Lung | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Mesothelioma, Malignant | Carcinoma Breast Stage IV

Switzerland
National Cancer Institute (NCI)

Terminated

Tocilizumab for Patients With Cancer and COVID-19 Disease

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Pneumonia | Symptomatic COVID-19 Infection Laboratory-Confirmed | Severe Acute Respiratory Distress Syndrome | Pneumonitis

United States
National Cancer Institute (NCI)

Terminated

Amatuximab for High Mesothelin Cancers

Carcinoma, Non-Small-Cell Lung | Ovarian Neoplasms | Mesothelioma | Carcinoma, Pancreatic Ductal

United States
Frantz Viral Therapeutics, LLC
University of California, San Francisco; Laser Surgery Care; Amarex CRO; Anal Dysplasia...

Active, not recruiting

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL (anal HSIL HIV-)

HPV Infection | Anal Dysplasia | Anal High Grade Squamous Intraepithelial Lesion | Anal Precancerous Condition | AIN 2/3 | HPV Disease

United States
University of Washington

Completed

Project to Improve Communication About Serious Illness - Pilot Study (PICSI-P)

Diabetes Complications | Renal Insufficiency, Chronic | Dementia | Leukemia, Lymphocytic, Chronic, B-Cell | Peripheral Vascular Disease | Frail Elderly | Congestive Heart Failure | Malignant Neoplasm | Lung Disease Chronic | Liver Failures, Chronic

United States
Incyte Biosciences International Sàrl

Recruiting

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

Lymphoma | Acute Myeloid Leukemia | Leukemia | Acute Lymphoblastic Leukemia | Acute Lymphocytic Leukemia | Solid Tumors | Chronic Phase Chronic Myeloid Leukemia | Accelerated Phase Chronic Myeloid Leukemia | Blast Phase Chronic Myeloid Leukemia

Spain, Italy, France, Germany, United Kingdom, Belgium, Sweden, Denmark, Netherlands
Blueprint Medicines Corporation

Active, not recruiting

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditions

United States, Canada, Korea, Republic of, Japan, Taiwan
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia

Leukemia | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
GV20 Therapeutics

Recruiting

A Study of GV20-0251 in Patients With Solid Tumor Malignancies

Cholangiocarcinoma | Non-small Cell Lung Cancer | Endometrial Carcinoma | Head and Neck Carcinoma | Cutaneous Melanoma | Solid Tumor, Adult | Refractory Cancer | Adenocarcinoma of the Rectum | Bladder Urothelial Carcinoma | Adenocarcinoma of the Colon

United States
Mainline Biosciences, Inc.

Withdrawn

A Phase 1 Study to Evaluate Paclitaxel Conjugated CXC Receptor 4 Antagonist (MB1707) in Patients With Advanced Cancer

Breast Cancer | Pancreatic Neoplasms | Non Small Cell Lung Cancer | Advanced Solid Tumor | Ovary Cancer

Clinical Trials on Malignant Germ Cell Tumor

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