Clinical Trials on Malignant Haematological Disease

Total 380604 results

Chinese PLA General Hospital

Recruiting

Ruxolitinib and Decitabine for High Risk Hematological Malignancies

Peripheral Blood Stem Cell Transplantation

China
Centre Hospitalier Universitaire de Saint Etienne
Institut de Cancérologie de la Loire

Recruiting

Administration of Fibrinogen Concentrate for Refractory Bleeding (FORMAT)

Bleeding | Platelet Refractoriness | Hematological Patients

France
Clover Biopharmaceuticals AUS Pty Ltd

Completed

Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Pleural Effusions

Malignant Pleural Effusions

Australia
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Nab-Paclitaxel/STI-3031 Complex (AP160-Complex) for the Treatment of Advanced or Metastatic Solid Tumors

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Melanoma

United States
NRG Oncology
National Cancer Institute (NCI)

Terminated

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Pleural Biphasic Mesothelioma | Pleural Epithelioid Mesothelioma | Stage I Pleural Malignant Mesothelioma AJCC v8 | Stage IA Pleural Malignant Mesothelioma AJCC v8 | Stage IB Pleural Malignant Mesothelioma AJCC v8 | Stage II Pleural Malignant Mesothelioma AJCC v8 | Stage IIIA Pleural Malignant...

United States, Canada
Institut Paoli-Calmettes
INSERM-U1068

Recruiting

Immunological Follow-up After Allogeneic Hematopoietic Stem Cell Transplantation (SIA-CSH)

Malignant Hemopathy

France
Lagos State University

Unknown

The Safety and Efficacy of Jobelyn in the Treatment of Breast Cancer Patients

Haematological Abnormality

Nigeria
M.D. Anderson Cancer Center
Roche Pharma AG

Completed

Prevention of Osteoporosis in Bone Marrow Transplantation (BMT) Patients

Hematological Malignancies

United States
M.D. Anderson Cancer Center

Suspended

Assessment of Verbal Comprehension and Cognitive Processes in Patients Admitted to the Palliative and Supportive Care Unit

Hematopoietic and Lymphoid Cell Neoplasm | Locally Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Centre Hospitalier Universitaire de Saint Etienne
Institut de Cancérologie de la Loire; Université Jean Monnet de Saint-Etienne

Recruiting

Biomarkers Impact Evaluation on the Post-transplant Immune Response After Allografting of Hematopoietic Stem Cells (MENTALO)

Malignant Hemopathy

France
Jinling Hospital, China
National Natural Science Foundation of China

Unknown

Gastrointestinal Postoperative Early Enteral Nutrition: Immuno-enhanced Versus Standard Early Enteral Nutrition (ISEEN)

Gastrointestinal Malignant

China
Sheng Hu
Wuhan Binhui Biotechnology Co., Ltd.

Recruiting

Safety and Efficacy Study of Virus Activated Killer Immune Cells (VAK) for Malignant Pleural and Peritoneal Effusion

Malignant Pleural Effusion | Malignant Peritoneal Effusion

China
AstraZeneca

Active, not recruiting

Durvalumab and Tremelimumab for Pediatric Malignancies

Pediatric Cancer | Hematological Malignancies | Solid Tumor Pediatric

Spain, Italy, United States, United Kingdom, France, Netherlands, Germany
M.D. Anderson Cancer Center
Tempus AI

Active, not recruiting

Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT II)

Metastatic Malignant Neoplasm | Recurrent Malignant Neoplasm

United States
The University of Hong Kong

Completed

Study on Systemic and Airway Biomarkers in Haemopoietic Stem Cell Transplantation

Hematological Diseases

Hong Kong
National Cancer Institute (NCI)

Recruiting

Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Triple-Negative Breast Carcinoma

United States
Effector Therapeutics

Terminated

A Phase 1-2 Dose-Escalation and Cohort-Expansion Study of Oral Tomivosertib (eFT-508) in Subjects With Hematological Malignancies

Lymphoma

United States
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.
Children's Hospital of Fudan University

Unknown

Evaluate the Efficacy and Safety of the Prophylactic Use of PEG-rhG-CSF in Children With Hematological Malignancies

Lymphoma | Leukemia

China
Sidney Kimmel Cancer Center at Thomas Jefferson...

Active, not recruiting

2-Step Approach to Stem Cell Transplant in Treating Participants With Hematological Malignancies

Hematopoietic and Lymphoid Cell Neoplasm

United States
National Cancer Institute (NCI)

Completed

Cediranib Maleate in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By Surgery

Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Epithelial Mesothelioma | Sarcomatous Mesothelioma | Localized Malignant Mesothelioma

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma

Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Epithelial Mesothelioma | Sarcomatous Mesothelioma | Localized Malignant Mesothelioma

United States
City of Hope Medical Center
National Cancer Institute (NCI); California Institute for Regenerative Medicine...

Recruiting

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

Breast Cancer | HER2-positive Breast Cancer | Malignant Neoplasm | Metastatic Malignant Neoplasm in the Brain | Metastatic Malignant Neoplasm in the Leptomeninges

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Completed

Use of Virtual Reality Goggles During Chemotherapy Infusion to Reduce Anxiety-Related Symptoms

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm | Malignant Thoracic Neoplasm | Malignant Head and Neck Neoplasm | Malignant Breast Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes

BRCA1 Gene Mutation | BRCA2 Gene Mutation | Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | PALB2 Gene Mutation | ATM Gene Mutation

United States
National Cancer Institute (NCI)

Completed

NHS-IL12 for Solid Tumors

Epithelial Tumors, Malignant | Epithelial Neoplasms, Malignant | Malignant Mesenchymal Tumor

United States
Centre Francois Baclesse

Terminated

Impact of the Paramedic Announced Consultation on the Use of Patient Care With Cancer and Treated With Chemotherapy (ANNONCEP)

Solid or Lymphoid Malignant Disease

France
Hutchmed

Recruiting

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

Isocitrate Dehydrogenase Gene Mutation

Spain, United States
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

Mesenchymal Stem Cells Combined With Cord Blood for Treatment of Graft Failure

Mesenchymal Stem Cells | Hematopoietic Stem Cell Transplantation | Hematological Diseases | Graft Failure | Umbilical Cord Blood

China
University of Chicago
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab in Treating Patients With Malignant Mesothelioma

Biphasic Mesothelioma | Epithelioid Mesothelioma | Peritoneal Malignant Mesothelioma | Pleural Biphasic Mesothelioma | Pleural Epithelioid Mesothelioma | Pleural Malignant Mesothelioma | Pleural Sarcomatoid Mesothelioma | Recurrent Peritoneal Malignant Mesothelioma | Recurrent Pleural Malignant Mesothelioma and other conditions

United States
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of QLF31907 Combination Therapy in Patients With Advanced Malignant Tumors

Advanced Malignant Neoplasm
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Trial of TQB3006 Tablets in Patients With Advanced Malignant Cancer

Advanced Malignant Neoplasm

China
Ain Shams University

Recruiting

Effectiveness of Topical Magnetite Zinc Oxide Composite Nanoparticles in the Management of Oral Potentially Malignant Lesions

Oral Potentially Malignant Lesions

Egypt
NextPoint Therapeutics, Inc.

Recruiting

A Study of NPX887 for Participants With Solid Tumors Known to Express HHLA2/B7-H7

Metastatic Malignant Neoplasm

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Study to Evaluate Drug-Drug Interaction of TQB3909 Tablets

Advanced Malignant Neoplasm

China
Hangzhou Sumgen Biotech Co., Ltd.

Recruiting

SG2918 For Advanced Malignant Tumors

Advanced Malignant Tumors

China
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

Phase I Study of SHR-2022 Injection in the Treatment of Patients With Advanced Malignant Tumors

Advanced Malignant Cancer
Genmab
BioNTech SE

Recruiting

A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors

Malignant Solid Tumor

Japan
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Clinical Study of TQB3912 Tablets in Patients With Advanced Malignant Tumor

Advanced Malignant Neoplasm

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Phase I Study of HRS-7053 Injection in the Treatment of Patients With Advanced Malignancies

Advanced Malignant Cancer
NovaRock Biotherapeutics, Ltd

Recruiting

A Study of NBL-020 Injection in Subjects With Advanced Malignant Tumors.

Advanced Malignant Tumors

China
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Recruiting

Clinical Trial Evaluating the Safety of the TQB2103 for Injection

Advanced Malignant Neoplasm

China
Akeso

Recruiting

A Phase Ia/Ib Open Label，Clinical Study Evaluating the Safety, Tolerability and Preliminary Efficacy of AK127 in Combination With AK104 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors

China
Shandong Suncadia Medicine Co., Ltd.

Recruiting

Phase I Clinical Study of HRS-2189 in the Treatment of Patients With Advanced Malignant Tumors

Advanced Malignant Tumor

China
UNC Lineberger Comprehensive Cancer Center

Recruiting

Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers

Cancer | Malignant Neoplasm

United States
Nanjing Leads Biolabs Co.,Ltd

Recruiting

A Phase I/II Clinical Trial of LBL-033 in the Treatment of Advanced Malignant Tumors

Advanced Malignant Tumors

China
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Dose Escalation and Expansion Study of SYH2043 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors

China
Peking University Cancer Hospital & Institute

Recruiting

Evaluate the Safety and Tolerability of JCXH-212 Monotherapy and Combined With Toripalimab in the Treatment of Malignant Solid Tumors

Malignant Solid Tumors

China
GeneScience Pharmaceuticals Co., Ltd.

Recruiting

Genakumab Alone and in Combination With Tislelizumab in Patients With Advanced Malignant Solid Tumors

Malignant Solid Tumors

China
SUNHO（China）BioPharmaceutical CO., Ltd.

Recruiting

A Clinical Trial to Evaluate Effect of IAP0971 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors

China
National Cancer Institute (NCI)

Recruiting

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

Malignant Solid Neoplasm

United States

Clinical Trials on Malignant Haematological Disease

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