Clinical Trials on Mediastinal Diseases

Total 382037 results

David Bond, MD

Recruiting

Tafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell Lymphoma

Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent... and other conditions

United States
University of Washington
Genentech, Inc.

Suspended

Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Untreated Aggressive Large B-cell Lymphoma

Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Aggressive Non-Hodgkin Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma, Not Otherwise Specified | T-Cell/Histiocyte-Rich... and other conditions

United States
Patrick C. Johnson, MD
AstraZeneca

Recruiting

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Refractory B-Cell Non-Hodgkin Lymphoma | Diffuse Large B-cell Lymphoma (DLBCL) | Grade 3b Follicular Lymphoma | Refractory Aggressive B-cell Lymphomas | Aggressive B-cell NHL | De Novo or Transformed Indolent B-cell Lymphoma | DLBCL, Nos Genetic Subtypes | T Cell/Histiocyte-rich Large B-cell Lymphoma and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and External Beam Radiation Therapy in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Refractory T-Cell Non-Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent T-Cell Non-Hodgkin Lymphoma | Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma | Refractory Transformed... and other conditions

United States
University Hospital Southampton NHS Foundation...

Completed

Immune Responses to COVID-19 Vaccination in Lymphoma Patients (PROSECO)

Follicular Lymphoma | Burkitt Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Peripheral T-cell Lymphoma | Diffuse Large B Cell Lymphoma | Classical Hodgkin Lymphoma | Small Lymphocytic Lymphoma | High-grade B-cell Lymphoma | Nodular Lymphocyte... and other conditions

United Kingdom
Calibr, a division of Scripps Research

Enrolling by invitation

Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T

Transformed Follicular Lymphoma | Burkitt Lymphoma | Waldenstrom Macroglobulinemia | Lymphoplasmacytic Lymphoma | Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Primary Mediastinal Large B Cell Lymphoma | Diffuse Large B-Cell Lymphoma (DLBCL) | Mantle Cell Lymphoma (MCL) | Follicular... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

Plasmablastic Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

Diffuse Large B-Cell Lymphoma | Chronic Lymphocytic Leukemia | Anaplastic Large Cell Lymphoma | Small Lymphocytic Lymphoma | Angioimmunoblastic T-Cell Lymphoma | Hepatosplenic T-Cell Lymphoma | Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Aggressive Non-Hodgkin Lymphoma | Enteropathy-Associated... and other conditions

United States
Kami Maddocks
National Cancer Institute (NCI)

Completed

Pembrolizumab and Ibrutinib in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Mantle Cell Lymphoma | Recurrent Burkitt Lymphoma | Recurrent... and other conditions

United States
University of Florida
Monteris Medical

Terminated

LITT and Pembrolizumab in Recurrent Brain Metastasis (TORCH)

Melanoma | Primary Mediastinal Large B-Cell Lymphoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Esophageal Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Cancer | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Merkel Cell Carcinoma | Brain Metastases, Adult | Renal Cell... and other conditions

United States
Schrödinger, Inc.

Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

Follicular Lymphoma | Splenic Marginal Zone Lymphoma | Burkitt Lymphoma | Plasmablastic Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Non Hodgkin Lymphoma | Primary Effusion Lymphoma | DLBCL | High-grade B-cell Lymphoma | Primary Mediastinal... and other conditions

United States, Moldova, Republic of
M.D. Anderson Cancer Center

Recruiting

ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma

Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Richter Syndrome | Refractory Mantle Cell Lymphoma | Refractory Aggressive B-Cell Non-Hodgkin Lymphoma | Refractory High Grade B-Cell Lymphoma | Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma | Refractory... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Salvia Hispanica Seed in Reducing Risk of Disease Recurrence in Patients With Non-Hodgkin Lymphoma

Diffuse Large B-Cell Lymphoma | Splenic Marginal Zone Lymphoma | Mantle Cell Lymphoma | Mycosis Fungoides | Sezary Syndrome | Lymphoplasmacytic Lymphoma | Anaplastic Large Cell Lymphoma | Blastic Plasmacytoid Dendritic Cell Neoplasm | Primary Effusion Lymphoma | Adult T-Cell Leukemia/Lymphoma | Post-Transplant... and other conditions

United States
University of Michigan
National Institutes of Health (NIH); National Institute of Dental and Craniofacial...

Completed

The Importance of Periostin in Periodontal Health and Disease

Periodontal Disease | Non-diseased Patients

United States
Yonsei University

Active, not recruiting

Low-Density Lipoprotein Cholesterol-targeting Statin Therapy Versus the Intensity-based Statin Therapy in Patients With Coronary Artery Disease (LODESTAR)

Coronary Artery Diseasse

Korea, Republic of
Gangnam Severance Hospital

Recruiting

Prevalence of Marginal Ulcer After PPPD and Preventive Effect of Proton Pump Inhibitor in Korea: A Prospective Multicenter Study

Pancretic Dissease (Benign/Malignancy) | BIle Duct Diseae(Benign/Malignancy) | Ampulla of Vater Disease (Benign/Malignancy)

Korea, Republic of
Eisai Co., Ltd.

Completed

Post-marketing Surveillance of Donepezil Hydrochloride Investigation of the Safety and Effectiveness of Combination Therapy of Donepezil Hydrochloride and Memantine Hydrochloride in Patients With Alzheimer's Disease

Alzheimer's Desease

Japan
Central Hospital, Nancy, France
Institut Régional de Médecine Physique et de Réadaptation

Unknown

Interest of Hydrophysiotherapy Care in Parkinson Disease's Motor and Non-motor Symptoms (THERMAPARK)

Interest of Hydrophysiotherapy Care in Parkinson Disease's Non-motor Symptoms
First Affiliated Hospital of Wenzhou Medical University

Completed

Tongue Image Database and Diagnostic Model for Digestive Tract Disease Diagnosis

Liver Diseases | Small Bowel Disease | Colorectal Disease | Gastric Diseases | Digestive Tract Diseases

China
Facet Biotech

Completed

A Humanized Anti-Interferon-γ Monoclonal Antibody (HuZAF) for Moderate to Severe Crohn's Disease

Crohn's Disease | Colitis | Digestive System Disease | Gastrointestinal Disease | Intestinal Disease

United States, Canada
First Affiliated Hospital of Harbin Medical University

Unknown

Water Injection Colonoscopy vs Air Insufflation Colonoscopy in Experienced Endoscopists

Colon Disease; | Rectal Disease;

China
Boston Children's Hospital

Recruiting

Allogeneic Valve Transplantation

Valve Disease, Heart | Valve Heart Disease | Valve Disease, Aortic

United States
McMaster Children's Hospital
St. Justine's Hospital

Completed

PediCRaFT: Pediatric Crohn's Disease Fecal Transplant Trial (PediCRaFT)

Inflammatory Bowel Diseases | Crohn Disease | Colitis | Pediatric Crohns Disease

Canada
Klinikum Westbrandenburg GmbH

Unknown

TOPIT; Trough Level Optimized Pediatric Inflammatory Bowel Disease Therapy: A Multicenter Study Comparing Effectiveness of Trough Level Optimized Infliximab Maintenance Therapy With Standard Dosing Regimen of Pediatric Patients With Crohn's Disease (TOPIT)

Pediatric Crohns Disease
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Raynaud's Treatment Study (RTS)

Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Raynaud's Disease
Hospices Civils de Lyon

Not yet recruiting

Autophagy in Paediatric Crohn's Disease (P-IBDphagy)

Crohn Disease | Pediatric Crohns Disease

France
Academisch Medisch Centrum - Universiteit van Amsterdam...
Celltrion

Recruiting

inDuctIon tREatment With subCuTaneous Infliximab for Crohn's Disease (DIRECTCD)

Bowel Disease | Inflammatory Disease | Disease Crohn

Netherlands
Fondazione IRCCS Policlinico San Matteo di Pavia
University of Pavia

Recruiting

Calcific Aortic Valve Disease:the Role of Bacteria as Trigger of a Chronic Inflammation

Calcific Aortic Valve Diasease

Italy
First Affiliated Hospital of Harbin Medical University

Unknown

"Air Assisted"Water Injection Colonoscopy in Experienced Endoscopists

Colon Disease; | Rectal Disease

China
Medtronic - MITG

Completed

Retrospective Collection of PillCam SB Movies (OCEAN)

Inflammatory Bowel Disease, Crohn Disease

Israel
University of Leicester

Recruiting

Usability and Acceptability Study of the P-STEP Mobile Application

Heart Failure | Chronic Obstructive Pulmonary Disease | Asthma | Type 2 Diabetes | Coronary Heart Disease | Interstitial Lung Disease

United Kingdom
The Second Hospital of Nanjing Medical University
Air Force Military Medical University, China

Recruiting

Standardized Fecal Microbiota Transplantation for Crohn&Apos;s Diseases

Inflammatory Bowel Disease | Crohn's Diseases

China
University of Bern
Merck Sharp & Dohme LLC; University Hospital, Basel, Switzerland; University... and other collaborators

Completed

Significance of Ficolin 2 in the Determination of Serological Activity in Chronic Inflammatory Bowel Disease

Crohn Disease

Switzerland
Morphic Therapeutic, Inc

Recruiting

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (GARNET)

Inflammatory Bowel Diseases | Crohn's Disease

United States, Georgia, Poland
Qu Biologics Inc.

Completed

Safety and Treatment Effect of QBECO in Moderate to Severe Crohn's Disease

Crohn's Disease | Inflammatory Bowel Disease

Canada
Fundación Pública Andaluza Progreso y Salud
Telefónica S.A.; Agency of Social Services and Dependency of Andalusia; Salud...

Unknown

Integral Clinical Plan Shared With or Without Telemonitoring of Constants in Patient With Chronic Diseases (ATLAN_TIC01)

Chronic Lung Disease | Chronic Heart Disease

Spain
National Institutes of Health Clinical Center (CC)

Completed

Translational Development of Photon-counting CT Imaging

Vascular Diseases | Cancer | Metabolic Bone Disease | Inflammatory Disease

United States
Children's Hospital Los Angeles

Completed

FMT in Pediatric Crohn's Disease (FMTPCD)

Crohn Disease | Pediatric Crohns Disease

United States
University of North Carolina, Chapel Hill
University of Amsterdam; Crohn's and Colitis Foundation

Recruiting

Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD) (PAZAZ)

Crohn Disease | Pediatric Crohns Disease

Netherlands, United States, Canada, Israel
Ryazan State Medical University

Completed

Chronic Obstructive Pulmonary Disease in Combination With Atherosclerosis (Clinical and Biochemical Study)

Chronic Obstructive Pulmonary Disease | Peripheral Artery Disease

Russian Federation
National Institutes of Health Clinical Center (CC)
National Institute of Allergy and Infectious Diseases (NIAID); Novartis

Terminated

NIH Substudy of AIN457 (Anti-IL-17 Monoclonal Antibody) for Treatment of Moderate to Severe Crohn's Disease

Crohn's Disease | Colitis | Inflammatory Bowel Disease

United States
Children's Hospital Medical Center, Cincinnati
Genentech, Inc.

Completed

Trial of Growth Hormone Therapy in Pediatric Crohn's Disease

Crohn's Disease

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Clinical Study of TA-650 in Pediatric Patients With Crohn's Disease

Pediatric Crohn's Disease

Japan
AbbVie

Completed

Post-Marketing Surveillance of Humira in Korean Pediatric Crohn's Disease (CD) Patients Under the "New-Drug Re-examination"

Pediatric Crohn's Disease
Prof. Arie Levine

Completed

Partial Enteral Nutrition With a Unique Diet vs. Exclusive Enteral Nutrition for the Treatment of Pediatric Crohn's Disease

Crohn's Disease

Canada, Israel
Prof. Arie Levine

Completed

Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease

Crohn's Disease

Israel
Children's Hospital of Philadelphia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Bone Health in Pediatric Crohn's Disease: A Low Magnitude Mechanical Stimulus Trial

Crohn Disease

United States
Janssen Pharmaceutical K.K.

Active, not recruiting

A Study of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

Crohns Disease

Japan
University of Michigan

Completed

Comparative Effectiveness of MR Enterography

Crohns Disease

United States
Baylor College of Medicine
UCB Pharma

Terminated

EUS Evaluation of Perianal and Peri-rectal Fistulizing Crohn's Disease With CERTOLIZUMAB Treatment (EUS)

Crohns Disease

United States

Clinical Trials on Mediastinal Diseases

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