Clinical Trials on Mediastinal Emphysema

Total 672 results

Seoul St. Mary's Hospital
Incheon St.Mary's Hospital

Completed

Effects of Drainage in Laparoscopic Cholecystectomy

Acute Cholecystitis | Empyema of Gallbladder | Abscess of Gallbladder

Korea, Republic of
University of Colorado, Denver
Omni Bio Pharmaceutical, Inc.

Completed

The Effects of Alpha-1 Antitrypsin (AAT) on the Progression of Type 1 Diabetes

Diabetes | Type 1 Diabetes

United States
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Suspended

Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) (LOGIC)

Liver Diseases | Alpha 1-Antitrypsin Deficiency | Alagille Syndrome

United States, Canada
Centre Henri Becquerel

Recruiting

Circulating Tumor DNA in Primary Mediastinal Large B-cell Lymphoma (PMBL) (CAMIL)

Primary Mediastinal Large B-cell Lymphoma

France
Merck Sharp & Dohme LLC

Terminated

Efficacy, Immunogenicity, and Safety of a Single Dose of V710 in Adult Patients Scheduled for Cardiothoracic Surgery (V710-003 AM2)

Bacteremia | Staphylococcus Aureus | Mediastinitis
Assiut University

Not yet recruiting

Is Intercostal Tube Enough in Management of Empyema

Empyema
Mayo Clinic

Completed

Feasibility of a Multi Component Intervention in Patients With Severe Dyspnea and Obesity

Lung Diseases | Emphysema | COPD

United States
Ruijin Hospital

Recruiting

Zanubrutinib Combined With Tislelizumab in the Treatment of r/r PMBCL and EBV+ DLBCL

Primary Mediastinal Large B Cell Lymphoma | EBV-Positive DLBCL, Nos

China
IRCCS San Raffaele

Recruiting

Primary Mediastinal Large B-cell Lymphoma With CNS Involvement

Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Italy
Stanford University

Withdrawn

Pilot Study of alpha1-antitrypsin to Treat Neuromyelitis Optica Relapses (A1AT for NMO)

Neuromyelitis Optica

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Terminated

Study of TQB2450 Injection in Subjects With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma

Relapsed or Refractory Primary Mediastinal B-cell Lymphoma (rrPMBCL)

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); AstraZeneca; Juno Therapeutics, Inc.; MedImmune...

Terminated

JCAR014 and Durvalumab in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

United States
Nicola Goekbuget

Completed

Newly Diagnosed Mature B-ALL, Burkitt's Lymphoma and Other High-grade Lymphoma in Adults

Lymphoblastic Lymphoma | Burkitt's Lymphoma | Mediastinal Neoplasms | Burkitt's Leukemia | Large Cell Anaplastic Lymphoma

Germany
University Medical Center Groningen

Completed

Identifying REsponders and Exploring Mechanisms of ACTION of the Endobronchial Coil Treatment for Emphysema (REACTION)

Chronic Obstructive Pulmonary Disease (COPD)

Netherlands, United Kingdom
Aga Khan University

Recruiting

Comparison Between McGrath and Macintosh Laryngoscopes for DLT Intubation in Thoracic Surgery Patients.

Thoracic Neoplasms | Thoracic Diseases | Thoracic Empyema

Pakistan
CSA Medical, Inc.
Reset Medical, Inc.

Withdrawn

CryoSpray Ablation(tm)Thoracic Patient Registry

Asthma | Emphysema | Lung Cancer | Mesothelioma | COPD | Sarcoidosis | Chronic Bronchitis
US Department of Veterans Affairs

Completed

Cost-Effectiveness of Lung Volume Reduction Surgery

Chronic Obstructive Pulmonary Disease | Emphysema

United States
Royal Brompton & Harefield NHS Foundation Trust
Heidelberg University; Chelsea and Westminster NHS Foundation Trust

Withdrawn

EBUS-TBNA Versus EBUS-TBNB

Lymphoma | Carcinoma | Sarcoidosis | Mediastinal Lymphadenopathy | Hilar Lymphadenopathy | Mycobacterial Disease

United Kingdom, Germany
Emilia Nozawa, PT PhD
University of Sao Paulo

Completed

Physiotherapy Exercises in Patients With Sternal Instability After Cardiovascular Surgery

Coronary Artery Disease | Cardiovascular Infections | Mediastinitis
Mayo Clinic

Not yet recruiting

Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicated Parapneumonic Effusion

Pleural Infection

United States
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Pilot Study of Tetomilast in Chronic Obstructive Pulmonary Disease (COPD) Associated With Emphysema (EMPHASIS)

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca

Completed

Efficacy Study of the Effect of Budesonide on Emphysema

Chronic Obstructive Pulmonary Disease

Denmark
Imperial College London
Gene Logic

Completed

Regulation of Inflammatory Mediators in Chronic Obstructive Pulmonary Disease

Emphysema | COPD

United Kingdom
Weill Medical College of Cornell University

Completed

Evaluation of the Lungs of Individuals With Lung Disease

Asthma | Emphysema | Lung Disease | Bronchitis | COPD

United States
Mayo Clinic

Completed

A Phase I Study of iPS Cell Generation From Patients With COPD

Respiratory Tract Diseases | Carcinoma, Non-Small-Cell Lung | Lung Diseases, Obstructive | Pulmonary Emphysema | Lung Cancer | Neoplasms, Lung | Thoracic Diseases | Carcinoma, Small Cell | COPD | Pulmonary Neoplasms | Neoplasms, Pulmonary | Pulmonary Cancer | Cancer of Lung | Cancer of the Lung

United States
Denver Health and Hospital Authority

Completed

Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication

Coagulopathy | Empyema, Pleural | Parapneumonic Effusion

United States
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE) (FORCE)

Portal Hypertension | Cholestasis | Liver Fibrosis | Biliary Atresia | Alagille Syndrome | Alpha1 Anti-Trypsin Deficiency

United States, Canada
Mayo Clinic
Minnesota HealthSolutions

Completed

Home-based Health Management of Chronic Obstructive Lung Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease | Emphysema | Pulmonary Rehabilitation

United States
Gilead Sciences

Withdrawn

Idelalisib With Rituximab, Ifosfamide, Carboplatin, Etoposide (RICE) in Children and Adolescents

Diffuse Large B-Cell Lymphoma | Mediastinal B-cell Lymphoma

Italy, Spain, France, Poland
China-Japan Friendship Hospital

Not yet recruiting

Safety and Efficacy of Endobronchial Valve for Bronchoscopic Lung Volume Reduction Surgery: A Prospective Pilot Study

Chronic Obstructive Pulmonary Disease | Emphysema

China
Imperial College London
Novartis; Boehringer Ingelheim; Royal Brompton & Harefield NHS Foundation Trust

Completed

Regulation of the Release of Inflammatory Mediators From Lung Macrophages.

Emphysema | COPD | Chronic Bronchitis

United Kingdom
University of Washington
National Institutes of Health (NIH)

Completed

Real-Time Support for Exercise Persistence in COPD

Pulmonary Disease, Chronic Obstructive | Emphysema | COPD | Chronic Bronchitis

United States
Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Unknown

Endothelial Dysfunction, Biomarkers, and Lung Function -Ancillary to MESA (MESA-LUNG)

Emphysema | Endothelial Dysfunction | Chronic Obstructive Pulmonary Disease (COPD)
Ruijin Hospital

Recruiting

Simultaneous Integrated Boost for Mediastinal Lymph Node Recurrence After Radical Surgery of Esophageal Cancer

Esophageal Cancer | Salvage Radiotherapy | Dose-escalation | Mediastinal Lymph Node Recurrence

China
Chang Gung Memorial Hospital

Not yet recruiting

Lymphoma Patients Undergoing Mediastinal Radiotherapy in the Era of Modern Chemoradiation

Hodgkin Lymphoma | Non Hodgkin Lymphoma | Mediastinal Lymphoma

Taiwan
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68)

Hodgkin's Lymphoma | Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Canada, United States, Brazil, Czechia, France, Italy, Poland, Russian Federation, South Africa, Turkey, Ukraine
Azienda Ospedaliero, Universitaria Ospedali Riuniti

Completed

Conventional Versus Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis of Hilar/Mediastinal Lymphadenopathies

Lymphoma | Lung Neoplasms | Sarcoidosis | Mediastinal Lymphadenopathy | Hilar Lymphadenopathy

Italy
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Polatuzumab Vedotin, Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Transformed B-Cell Non-Hodgkin Lymphoma | Refractory Transformed B-Cell Non-Hodgkin Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma | Refractory Primary Mediastinal (Thymic)... and other conditions

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

R-ICE and Lenalidomide in Treating Patients With First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma

Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent... and other conditions

United States
Hospital General Ajusco Medio
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Completed

VATS for Resection of Mediastinal Parathyroids

Hyperparathyroidism | Mediastinal Parathyroid Adenoma
Johns Hopkins University
Centers for Medicare and Medicaid Services; Hill-Rom

Completed

Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation

Emphysema | COPD | Chronic Bronchitis

United States
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Home Pulmonary Rehabilitation for COPD

Emphysema | Chronic Obstructive Pulmonary Disease (COPD)

United States
Imperial College London

Completed

Leukocyte Function in Chronic Obstructive Pulmonary Disease (COPD)

Emphysema | COPD | Chronic Bronchitis

United Kingdom
McGill University Health Centre/Research Institute...

Completed

Eccentric Exercise Training as Novel Rehabilitation for Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive | Emphysema | Bronchitis, Chronic

Canada
University Health Network, Toronto
Novartis

Completed

Study Comparing Simulect Plus Standard Immunosuppression to Standard Immunosuppression Alone for the Prevention of Acute Rejection and Bronchiolitis Obliterans in Lung Transplant

Emphysema | COPD | Alpha-1 Antitrypsan Deficiency

Canada
Merck Sharp & Dohme LLC

Completed

Study of Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma or Relapsed or Refractory Richter Syndrome (MK-3475-170/KEYNOTE-170)

Richter Syndrome | Mediastinal Large B-cell Lymphoma
Milton S. Hershey Medical Center

Terminated

Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound

Pneumonia | Mediastinal Lymphadenopathy | Bronchiectasis Adult | Chest--Diseases | Cancer, Lung | Bronchopulmonary Disease | Infiltrates

United States
Samsung Medical Center

Completed

Pilot Study of Ruxolitinib in Relapsed or Refractory Hodgkin Lymphoma and Primary Mediastinal Large B-cell Lymphoma (JAK2)

Primary Mediastinal Large B-cell Lymphoma | Relapsed or Refractory Hodgkin Lymphoma

Korea, Republic of
Medical University of Warsaw

Unknown

Bronchoscopic Sampling Techniques in Sarcoidosis

Tuberculosis | Sarcoidosis | Lymphomas | Mediastinal Lymph Node Enlargement

Poland
University College London Hospitals

Unknown

A Clinical tRial of Endobronchial Ultrasound for the Diagnosis of MEDiastinal lymphadenopathY (REMEDY) (REMEDY)

Lymphoma | Lung Cancer | Tuberculosis | Sarcoidosis | Isolated Mediastinal Lymphadenopathy

United Kingdom

Clinical Trials on Mediastinal Emphysema

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