Clinical Trials on Mediation

Total 2375 results

Sound Pharmaceuticals, Incorporated
VA Puget Sound Health Care System

Unknown

SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

Head and Neck Cancer | Lung Cancer | Hearing Loss | Ototoxicity | Tinnitus | Neuropathy

United States
Wuerzburg University Hospital
Charite University, Berlin, Germany; University Hospital Muenster; Health Care...

Recruiting

MigALastat Therapy Adherence Among FABRY Patients: A Prospective Multicentral Observational Study (MALTA-FABRY)

Quality of Life | Adherence, Medication | Fabry Disease | Rare Diseases

Germany
McGill University Health Centre/Research Institute...

Completed

Electronic Decision Support for Deprescribing in Patients on Hemodialysis (MedSafer-HD)

Hypertension | Anemia | End Stage Renal Disease | Renal Failure Chronic | Diabete Type 2 | Medication Interaction

Canada
Tulane University
National Kidney Foundation

Completed

Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes

Depression | Quality of Life | Pain | Generalized Anxiety Disorder | End Stage Renal Disease | Anxiety | Blood Pressure | Major Depressive Disorder | Compliance, Patient | Compliance, Medication | Mood | Heart Rate Fast | Energy Supply; Deficiency

United States
Nanfang Hospital, Southern Medical University

Recruiting

A Mucosal Contouring Method Based on Swallowing-induced Breakthrough Pain for Radiation-induced Oropharyngeal Mucositis

Radiation-induced Oropharyngeal Mucositis | Swallowing-induced Breakthrough Pain

China
Qilu Hospital of Shandong University

Recruiting

Cardiac Toxicity and Prognostic Value of New Echocardiographic Indicators in the Treatment of Primary Multiple Myeloma

Multiple Myeloma

China
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer

Cardiotoxicity | Recurrent Breast Carcinoma | HER2/Neu Positive | Metastatic Malignant Neoplasm in the Brain | Stage IV Breast Cancer AJCC v6 and v7

United States, Korea, Republic of, Puerto Rico, Saudi Arabia
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Unknown

Treatment of Bevacizumab Followed by Steroid in RN

Brain Injuries | Nasopharyngeal Carcinoma | Adverse Effect of Radiation Therapy

China
Arbeitsgemeinschaft medikamentoese Tumortherapie

Completed

Multicentre Study to Determine the Cardiotoxicity of R-CHOP Compared to R-COMP in Patients With Diffuse Large B-Cell Lymphoma (NHL-14)

Diffuse Large B-Cell Lymphoma

Austria
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy, Surgery, and Radiation Therapy With or Without Dexrazoxane and Trastuzumab in Treating Women With Stage III or Stage IV Breast Cancer

Inflammatory Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Cardiac Toxicity

United States
University Hospital, Bonn

Unknown

Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms (IESA)

Comorbidities | Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h) | Intracranial Aneurysm Size | Blood Pressure Medication | Complications (Subarachnoid Hemorrhage)

Germany
Medical College of Wisconsin
The Cleveland Clinic

Not yet recruiting

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

Ischemia | Coronary Artery Disease | Heart Failure | Hypertension | Diabetes Mellitus | Cardiomyopathies | Peripheral Artery Disease | Cardiotoxicity

United States
Montreal Heart Institute
AstraZeneca

Recruiting

Identification and Evaluation of Patients at Risk of Developing Cardiotoxicity After Receiving Chemotherapy for Breast Cancer, Lymphoma or Leukemia (CarChem)

Lymphoma | Leukemia | Breast Cancer

Canada
University of Nebraska
National Cancer Institute (NCI)

Completed

Cardiac Magnetic Resonance Imaging in Patients With Non-Hodgkin Lymphoma or Hodgkin Lymphoma Receiving Doxorubicin

Lymphoma | Cardiac Toxicity | Chemotherapeutic Agent Toxicity

United States
Second Affiliated Hospital, School of Medicine,...

Unknown

Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR

Myocardial Injury | Osteosarcoma | Cardiotoxicity | Doxorubicin Induced Cardiomyopathy | Chemotherapy Induced Systolic Dysfunction

China
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma

Recurrent Melanoma | Stage IV Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Nodular Malignant Melanoma | Solar Radiation-related Skin Melanoma | Superficial Spreading Malignant Melanoma

United States
Nanfang Hospital, Southern Medical University

Recruiting

A Real-world Observational Study of a Mucosal Contouring Method for Radiation-induced Oropharyngeal Mucositis

Radiation-induced Oropharyngeal Mucositis | Swallowing-induced Breakthrough Pain

China
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Photoacoustic Imaging for Measuring Tumors and Normal Tissue in Patients With Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma | Radiation Therapy Recipient | Head and Neck Lymph Node | Laryngeal Neoplasm

United States
Jiarong Chen, MD

Unknown

Comparison of Transdermal Fentanyl and Morphine for Oral Mucositis Pain in Nasopharyngeal Cancer Patients

Pain | Head and Neck Cancer | Nasopharyngeal Carcinoma | Radiation Induced Oral Mucositis
Guy's and St Thomas' NHS Foundation Trust
Sedana Medical

Recruiting

Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome (ISO-DRIVE)

Acute Respiratory Distress Syndrome | Mechanical Ventilation Complication | Sedation Complication

United Kingdom
University of Oxford
Mount Sinai Hospital, Canada

Completed

Sedation, ANalgesia and Delirium MANagement in Intensive Care Unit (SAnDMAN)

Critical Illness | Covid19 | Analgesia | Sedation Complication | Intensive Care Unit Delirium

United Kingdom
University Hospital Inselspital, Berne
University of Bern; Spital STS AG; Bürgerspital Solothurn; Lindenhofspital

Terminated

Cancer Adverse Effects PReventIon With Care & Exercise: the CAPRICE Study

Lymphoma | Physical Activity | Breast Neoplasm Female | Cardiotoxicity | Anthracyclines

Switzerland
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Colorectal Cancer | Anal Cancer | Drug/Agent Toxicity by Tissue/Organ | Radiation Enteritis

United States
University College, London

Recruiting

Cancer Treatment Related Cardiovascular Toxicity: Comprehensive Myocardial and Vascular Phenotyping (PC-TOX)

Cardiovascular Diseases | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Cardiotoxicity | Malignancy | Oesophagus Cancer | Fluorouracil Adverse Reaction

United Kingdom
Memorial Sloan Kettering Cancer Center

Recruiting

Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity

Breast Cancer | HER2-positive Breast Cancer | Cardiotoxicity | Breast Cancer Stage IV | Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Stage III | HER2-positive Metastatic Breast Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma (T-Cell #4)

Lymphoma | Leukemia | Cardiac Toxicity
The Cleveland Clinic

Recruiting

Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain

Erectile Dysfunction | Chronic Prostatitis | Chronic Pelvic Pain Syndrome | Erectile Dysfunction Following Radical Prostatectomy | Erectile Dysfunction Following Radiation Therapy | Erectile Dysfunction Due to Arterial Insufficiency | Erectile Dysfunction Due to Arterial Disease

United States
Affiliated Hospital of Qinghai University

Not yet recruiting

Cardiotoxicity of Targeted Therapy for HER-2 Positive Breast Cancer Patients at High Altitude

HER2-positive Breast Cancer | Targeted Therapy | Cardiac Toxicity | High Altitude

China
University of Santiago de Compostela

Completed

Photobiomodulation in Oral Lesions Resulting From Anti-neoplastic Prevention

Head and Neck Cancer | Oral Cancer | Oral Mucositis | Osteoradionecrosis | Hyposalivation | Osteonecrosis Due to Drugs, Jaw | Osteonecroses, Bisphosphonate

Spain
KU Leuven
Jessa Hospital; University Hospital, Ghent; Universitair Ziekenhuis Brussel; Imelda... and other collaborators

Completed

CAre of Patients With PArenteral Nutrition At Home (CAPANAH)

Crohn's Disease | Chronic Diarrhea | Radiation Enteritis | Peritoneal Carcinomatosis With Intestinal Occlusion | Intestinal Lymphomas

Belgium
AHS Cancer Control Alberta
Cross Cancer Institute

Completed

A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma Patients (SUnitinib Prospective CardiovasculaR Effect) (SUPER)

Heart Failure | Renal Cell Carcinoma | Hypertension | Cardiotoxicity

Canada
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Pentoxifylline Treatment in Acute Pancreatitis (AP) (AP)

Acute Pancreatitis (AP) | Gallstone Pancreatitis | Alcoholic Pancreatitis | Trauma Acute Pancreatitis | Hypertriglyceridemia Acute Pancreatitis | Idiopathic (Unknown) Acute Pancreatitis | Medication Induced Acute Pancreatitis | Cancer Acute Pancreatitis | Miscellaneous (i.e. Acute on Chronic Pancreatitis)

United States
Sun Yat-sen University

Recruiting

Evaluation of Impedance Cardiography for Assessing Hemodynamic Shifts in Patients With LA-NSCLC During Treatment.

Non-small Cell Lung Cancer | Cardiac Toxicity

China
Dana-Farber Cancer Institute
AstraZeneca

Not yet recruiting

Cardiotoxicities in Patients Receiving BTKi

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors (SENTINEL)

Hypertension | Atrial Fibrillation | Chronic Lymphocytic Leukemia | Cardiotoxicity

United States
Abramson Cancer Center at Penn Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Pilot Study of an NTproBNP Guided Strategy of Cardioprotection (NTproBNP-Guide)

Heart Failure | Lymphoma | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
Tanta University

Enrolling by invitation

Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients

Breast Cancer | Cognitive Impairment | Peripheral Neuropathy | Cardiac Toxicities | Hepatic Toxicity

Egypt
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Suspended

Atorvastatin in Preventing Nasopharyngeal Carcinoma Patients Receiving Radiotherapy From Carotid Stenosis

Nasopharyngeal Carcinoma | Radiation Therapy Complication

China
Silesian Centre for Heart Diseases
Medical Research Agency, Poland

Not yet recruiting

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Heart Failure | Breast Cancer | Breast Diseases | Cardiotoxicity | Molecular Mechanisms of Pharmacological Action | Angiotensin Receptor Antagonists | Neoplasm, Breast | Cardiac Toxicity | Angiotensin II Type 1 Receptor Blockers | Cancer, Therapy-Related | Antihypertensive Agents | Sacubitril/Valsartan | Cancer...

Poland
MuReva Phototherapy Inc.

Active, not recruiting

Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients

Head and Neck Cancer | Oral Mucositis (Ulcerative) | Oral Mucositis (Ulcerative) Due to Radiation | Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy

United States
Goethe University

Completed

Prospective Electroencephalography Evaluation of Sedation in COVID-19

Pathologic Processes | Acute Respiratory Distress Syndrome | Corona Virus Infection | Electroencephalogram | Conscious Sedation

Germany
Giulio Stefanini
Agenzia Italiana del Farmaco

Active, not recruiting

Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines (CONTROL)

Lymphoma, Large B-Cell, Diffuse | Breast Cancer | Chemotherapy Effect | Cardiotoxicity | Left Ventricular Dysfunction

Italy
Dr Caeymaex Laurence
Ministry of Health, France; Paris 12 Val de Marne University

Completed

SEPREVEN: a Stepped-wedge Randomised Controlled Trial (SEPREVEN)

Nosocomial Pneumonia | Extravasation Injury | Skin Lesion | Intubation Complication | Intensive Care Units, Neonatal | Misadventures to Patients During Surgical and Medical Care | Catheter-related Bloodstream Infection (CRBSI) Nos | Quality of Healthcare | Ventilator Adverse Event | Immature Newborn | Nasal... and other conditions

France
Gynecologic Oncology Group
National Cancer Institute (NCI); Canadian Cancer Trials Group

Completed

Radiation Therapy and Cisplatin With or Without Epoetin Alfa in Treating Patients With Cervical Cancer and Anemia

Anemia | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Radiation Toxicity | Cervical Squamous Cell Carcinoma | Drug Toxicity | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage IVA Cervical Cancer

United States
Ain Shams University
Misr International University

Recruiting

Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity to Cisplatin Among Egyptian Non-small Cell Lung Cancer Patients

Non Small Cell Lung Cancer | Cardiotoxicity | Nephropathy

Egypt
University Hospital, Geneva

Recruiting

Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma

Ototoxicity | Vestibular Schwannoma

Switzerland
Thompson Cancer Survival Center

Recruiting

Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis

Laryngeal Cancer | Esophageal Cancer | Oropharynx Cancer | Oral Cavity Cancer | Mediastinal Cancer | Head and Neck Cancers - Tonsils | Chest Wall Tumor | Radiation Mucositis

United States
University of Chicago

Recruiting

Dyspnea and Cardiotoxicity in Multiple Myeloma Patients Who Receive Carfilzomib

Multiple Myeloma | Cardiotoxicity | Dyspnea | Shortness of Breath

United States
University of Baghdad

Completed

Using of Testes' Shocker in Improving Sexual Activity

Sexual Dysfunction | Erectile Dysfunction | Erectile Dysfunction Following Radical Prostatectomy | Erectile Dysfunction Following Radiation Therapy | Sexual Abstinence | Erectile Dysfunction With Diabetes Mellitus | Sexual Desire Disorder | Erectile Dysfunction Following Cryotherapy | Erectile Dysfunction... and other conditions

Iraq
Central Hospital Saint Quentin

Recruiting

4D CT Scan Versus 3D CT Scan Concerning Cardiac Dosimetry Assesment for Left Sided Breast Cancers Radiotherapy (RD3D4)

Breast Cancer | Left Anterior Descending Coronary Artery Stenosis | Radiotherapy Side Effect | Cardiac Ischemia | Left Sided Breast Cancer | Radiation-Induced Vascular Disease | LAD (Left Anterior Descending) Coronary Artery Stenosis

France

Clinical Trials on Mediation

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Medical Conditions

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Rare Diseases

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