Clinical Trials on Mental Disorder in Adolescence

Total 86150 results

Amsterdam UMC, location VUmc

Completed

Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study. (ROCKIES)

Type 2 Diabetes Mellitus | Diabetic Nephropathy | Diabetic Kidney Disease | Renal Hypoxia | Renoprotection | SGLT2 Inhibitor | Ertugliflozin

Netherlands
University of Florida
Mallinckrodt

Withdrawn

Early iNO for Oxidative Stress, Vascular Tone and Inflammation in Babies With Hypoxic Respiratory Failure

Persistent Fetal Circulation Syndrome | Persistent Pulmonary Hypertension of Newborn | Hypertension, Pulmonary, of Newborn, Persistent

United States
Epizyme, Inc.

No longer available

Tazemetostat Expanded Access Program for Adults With Solid Tumors

Renal Cell Carcinoma | Malignant Mesothelioma | Chondrosarcoma | Synovial Sarcoma | Renal Medullary Carcinoma | Malignant Rhabdoid Tumor | Poorly Differentiated Chordoma | Malignant Rhabdoid Tumor of Ovary | Epithelioid Malignant Peripheral Nerve Sheath Tumor | Sinonasal Carcinoma | Spindle Cell Sarcoma | Epithelioid... and other conditions
University of Sao Paulo General Hospital

Recruiting

SGLT-2 Inhibitors in Prevention of Post-procedural Renal and Cardiovascular Complications aFter PCI Among Patients With Diabetes Mellitus and Coronary Artery Disease: a Prospective, Randomized, Pilot Study (SAFE-PCI) (SAFE-PCI)

Coronary Artery Disease | Diabetes Mellitus, Type 2 | Acute Kidney Injury

Brazil
Faculty Hospital Kralovske Vinohrady

Completed

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Infections | Multiple Sclerosis | Autoimmune Diseases | Diabetes Mellitus, Type 1 | Rheumatoid Arthritis | Vaccine Reaction | Inflammatory Bowel Diseases | Psoriasis | Crohn Disease | Ulcerative Colitis | Down Syndrome | Atopic Dermatitis | Vitiligo | Alopecia Areata | COVID-19 Pandemic | Ankylosing Spondylitis | Lupus Erythematosus and other conditions

Czechia
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Effectiveness of Ketogenic Diet in MELAS Syndrome

MELAS Syndrome | Ketogenic Dieting

China
First Affiliated Hospital Xi'an Jiaotong University
Simcere Company

Recruiting

G6PD Deficiency in Infarction Patients in Shaanxi Province (GPS-IP)

Cerebral Infarction | G6PD Deficiency

China
Chinese University of Hong Kong

Recruiting

High Concentration Oxygen for Pneumocephalus After Evacuation of Chronic Subdural Haematoma (HOPE)

Recurrence | Chronic Subdural Hematoma | Oxycephaly

Hong Kong
Chen Chunlin
Chinese Academy of Sciences

Recruiting

The Application of Real-Time Near-infrared Imaging in Gynecological Surgery

Cervical Cancer | Endometriosis | Uterine Sarcoma | Adenomyosis | Endometrial Carcinoma | Ovarian Tumor | Ovarian Cyst Benign | Uterine Myomatosis | Ovarian Cyst Malignant

China
IntraBio Inc

Recruiting

N-Acetyl-L-Leucine for Ataxia-Telangiectasia (A-T)

Ataxia Telangiectasia | Louis Bar Syndrome

Spain, United States, Germany, United Kingdom
Scholar Rock, Inc.

Active, not recruiting

Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab-ONYX (ONYX)

Neuromuscular Diseases | Neuromuscular Manifestations | Atrophy | Muscular Atrophy | Spinal Muscular Atrophy | Muscular Atrophy, Spinal | Spinal Muscular Atrophy Type 3 | SMA | Anti-myostatin | Spinal Muscular Atrophy Type II

United States, Spain, Belgium, Germany, Netherlands, Poland, Italy, France, United Kingdom
Passage Bio, Inc.

Active, not recruiting

Study of Safety, Tolerability and Efficacy of PBGM01 in Pediatric Participants With GM1 Gangliosidosis (Imagine-1)

GM1 Gangliosidosis | GM1 Gangliosidosis, Type I | GM1 Gangliosidosis, Type 2 | Beta-Galactosidase-1 (GLB1) Deficiency

United States, Canada, United Kingdom, Turkey, Brazil
Hospital Universitario 12 de Octubre

Active, not recruiting

Clinical Long Term Evaluation of Glutamine Supplement in MELAS Syndrome

MELAS Syndrome

Spain
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Nurses' Health Study (Cardiovascular Component)

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus | Angina Pectoris | Menopause | Cerebrovascular Accident | Pulmonary Embolism | Postmenopause
Hospital for Special Surgery, New York

Completed

Effect of Topical Corticosteroids on Dysphagia in Anterior Cervical Discectomy and Fusion

Dysphagia | Cervical Disc Herniation | Cervical Degenerative Disc Disease | Cervical Spondylotic Myelopathy | Osteoarthritis of Cervical Spine
Dayton Children's Hospital

Active, not recruiting

Defining the Operating Characteristics of NIRS in the Diagnosis of Pediatric Traumatic Intracranial Hemorrhage

Traumatic Brain Injury | Intracranial Hemorrhages | Head Trauma | Hematoma of Head | Head Injuries | Craniocerebral Injuries | Head Injury, Minor | Traumatic Brain Hemorrhage

United States
Khondrion BV
Julius Clinical

Completed

The KHENERGYZE Study

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS Syndrome | Mitochondrial Encephalomyopathies | MIDD

Netherlands, Denmark, Germany, United Kingdom
University Hospital, Bordeaux

Completed

Impact of Changes in the Use of Care and Reorganization of the Healthcare System Linked to the Covid-19 Outbreak on the Quality of Care Pathways of Patients Suffering From Acute Myocardial Infarction and Stroke in Aquitaine (AVICOVID) (AVICOVID)

Stroke | Coronavirus Disease 2019 | Acute Myocardial Infarction

France
Dana-Farber Cancer Institute
Novartis; AstraZeneca

Completed

Phase I Study of the Oral PI3kinase Inhibitor BKM120 or BYL719 and the Oral PARP Inhibitor Olaparib in Patients With Recurrent Triple Negative Breast Cancer or High Grade Serous Ovarian Cancer

Breast Cancer | Ovarian Cancer

United States
Xiangya Hospital of Central South University

Unknown

Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases

Sepsis | Ischemic Stroke | TBI (Traumatic Brain Injury) | Subarachnoid Hemorrhage, Aneurysmal | ICH - Intracerebral Hemorrhage | HIE - Hypoxic - Ischemic Encephalopathy

China
Jean M. Tersak, M.D.
Genentech, Inc.

Terminated

Use of Rituximab in Opsoclonus-Myoclonus in Children With Neuroblastoma

Neuroblastoma | Opsoclonus-myoclonus
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pulmonary Hypertension, Hypoxia and Sickle Cell Disease

Sickle Cell Anemia | Pulmonary Hypertension | Cerebrovascular Disease | Chuvash Polycythemia

United States, Russian Federation
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

p53MVA Vaccine and Gemcitabine Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Ovarian Epithelial Cancer

United States
NHS Tayside
University of Dundee

Completed

Response of Individuals With Ataxia-Telangiectasia to Metformin and Pioglitazone (RAMP)

Ataxia-Telangiectasia

United Kingdom
Stanford University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Responses to Influenza Vaccine in Patients With Mitochondrial Disorders (MELAS)

MELAS Syndrome

United States
Cancer Research UK

Completed

Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer

Breast Cancer | Ovarian Cancer | brca1 Mutation Carrier | brca2 Mutation Carrier

United Kingdom
St. Jude Children's Research Hospital
National Cancer Institute (NCI); Children's Hospital of Philadelphia

Completed

Study for Treatment of Cancer in Children With Ataxia-telangiectasia

Ataxia-Telangiectasia

United States
Rigshospitalet, Denmark

Completed

MicroRNA Diagnostics in Subarachnoid Hemorrhage 2

Systemic Inflammatory Response Syndrome | Subarachnoid Hemorrhage | Acute Lung Injury | Delayed Cerebral Ischemia | Cardiac Dysfunction

Denmark
AGO Study Group
Philipps University Marburg Medical Center; HSK Reasearch GmbH Wiesbaden

Completed

Randomized Multicenter Trial With SU11248 Evaluating Dosage,Tolerability,Toxicity and Effectiveness of a Multitargeted Receptor Tyrosine Kinase Inhibitor

Platinum Refractory Epithelial Ovarian Cancer | Primary Cancer of the Peritoneum | Cancer of the Fallopian Tube

Germany
Genzyme, a Sanofi Company

Completed

rhGAA in Patients With Infantile-onset Glycogen Storage Disease-II (Pompe Disease)

Glycogen Storage Disease Type II | Acid Maltase Deficiency Disease | Glycogenosis 2 | Pompe Disease

United States, Israel, France, United Kingdom
Warwick Medical School

Unknown

Two Different Schedules of Carboplatin, Paclitaxel, Gemcitabine, and Surgery in Treating Patients With Newly Diagnosed Stage IIIC or Stage IV Primary Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

United Kingdom
National Cancer Institute (NCI)

Completed

Imatinib Mesylate in Treating Patients With Stage III or Stage IV Ovarian Epithelial or Primary Peritoneal Cancer

Stage IV Ovarian Epithelial Cancer | Primary Peritoneal Cavity Cancer | Recurrent Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer

United States
The University of Texas Health Science Center,...

Completed

Ketones & Mitochondrial Heteroplasmy

Mitochondrial Diseases | MELAS Syndrome

United States
Johns Hopkins University
Vascular Birthmarks Foundation

Completed

Use of the Atkins Diet for Children With Sturge Weber Syndrome

Epilepsy | Sturge Weber Syndrome

United States
China Medical University Hospital

Unknown

Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants

Retinopathy of Prematurity | Intraventricular Hemorrhage | Infant, Premature | Leukomalacia, Periventricular

Taiwan
Institute of Child Health
Great Ormond Street Hospital for Children NHS Foundation Trust

Completed

Conjugate Pneumococcal Vaccine in Ataxia Telangiectasia (AT)

Ataxia Telangiectasia (AT)

United Kingdom
GlaxoSmithKline

Completed

Study to Evaluate Antibody Persistence in Children Previously Vaccinated With Infanrix Hexa™ or Infanrix-IPV/Hib™

Hepatitis B | Tetanus | Diphtheria | Acellular Pertussis | Poliomyelitis | Haemophilus Influenzae Type b | Diphtheria-Tetanus-aPertussis-Poliomyelitis-Haemophilus Influenzae Type b Vaccines

Sweden, Norway
Masonic Cancer Center, University of Minnesota
National Institutes of Health (NIH)

Recruiting

Role of Acetaldehyde in the Development of Oral Cancer

Fanconi Anemia | Oral Cavity Carcinoma | Alcohol-Related Carcinoma

United States
Theravance Biopharma

Recruiting

Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy (CYPRESS)

MSA - Multiple System Atrophy | Symptomatic Neurogenic Orthostatic Hypotension

United States, Spain, United Kingdom, Hungary, Italy, Argentina, Austria, Poland, Germany, Portugal, Belgium, Brazil, Denmark, Canada, France, Chile, Estonia
University of Edinburgh
NHS Lothian; Prism Training and Consultancy; Simpsons Special Care Babies

Recruiting

Investigating Cerebral Oxygenation in the Newborn (ICON)

Neonatal Encephalopathy | Premature Infant Disease | Hypoxic Ischemic Encephalopathy of Newborn

United Kingdom
Shanghai Gynecologic Oncology Group
Fudan University

Not yet recruiting

Survival Effect of Hepato-celiac Lymphadenectomy In Primary or Relapsed Ovarian Cancer

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

China
Sohag University

Recruiting

Ahmed Valve Implantation Coated With Poly Lactic -Co-glycolic Acid (PLGA) Saturated With Mitomycin-C in the Management of Adult Onset Glaucoma in Sturge Weber Syndrome

Glaucoma

Egypt
Bio-Path Holdings, Inc.

Recruiting

BP1001-A in Patients With Advanced or Recurrent Solid Tumors

Fallopian Tube Neoplasms | Carcinoma, Ovarian Epithelial | Solid Tumor | Endometrial Cancer | Peritoneal Cancer | Solid Tumor, Adult

United States
National Cancer Institute, Naples

Recruiting

Olaparib in Patients With Recurrent Ovarian Cancer Wild Type for Germline and Somatic BRCA 1 and 2 Genes: The MITO 31 Translational Study (MITO 31)

BRCA Wild Type Platinum Sensitive Recurrent Ovarian Cancer

Italy
University of Puerto Rico
National Cancer Institute (NCI)

Recruiting

Familial Colorectal Cancer Registry in Hispanics (PURIFICAR)

Colorectal Neoplasms | Gastric Cancer | Colorectal Cancer | Lynch Syndrome | Colorectal Adenoma

Puerto Rico
University of Minnesota
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Recruiting

A Natural History Study of the Gangliosidoses

GM2 Gangliosidosis | GM1 Gangliosidosis | Tay-Sachs Disease | Sandhoff Disease | Late Onset Tay-Sachs Disease

United States
McGill University Health Centre/Research Institute...
St. Joseph's Healthcare Hamilton; University of British Columbia; University... and other collaborators

Active, not recruiting

Biosimilars of Rituximab in ANCA-associated Vasculitis Compared to the Originator (BRAVO)

Microscopic Polyangiitis | Granulomatosis With Polyangiitis | ANCA-associated Vasculitis

Canada
Brock University

Completed

Anti-inflammatory Diet Consultation for Those With Neuromuscular Disability

Multiple Sclerosis | Inflammation | Muscular Dystrophies | Spinal Cord Injuries | Diet Habit

Canada
Memorial Sloan Kettering Cancer Center

Completed

A Phase I Study of WT1 or NY-ESO-1 Vaccine and Nivolumab For Recurrent Ovarian Cancer

Ovarian Cancer | Primary Peritoneal Cancer | Recurrent Ovarian Cancer | Fallopian Tube

United States
Dana-Farber Cancer Institute
National Institute of Nursing Research (NINR)

Withdrawn

SIGNAL:Identifying Behavioral Anomalies Using Smartphones to Improve Cancer Care (SIGNAL)

Cervical Cancer | Gynecologic Cancer | Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma | Uterine Cancer

United States

Clinical Trials on Mental Disorder in Adolescence

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