Clinical Trials on Metabolic Syndrome in Postmenopausal Females in South Africa

Total 332 results

Sanofi
Procter and Gamble

Completed

Risedronate 75mg Dosed on 2 Consecutive Days Monthly in the Treatment of Osteoporosis in Postmenopausal Women

Osteoporosis Postmenopausal

France, United States, Australia, Canada, Lebanon, South Africa, Czech Republic, Turkey, Argentina, Poland, United Kingdom
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Resolution of Effect of Bisphosphonates on Bone in Postmenopausal Osteoporosis

Postmenopausal Osteoporosis

United Kingdom
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (ACT2)

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus | CIN2 | CIN3

South Africa
Alvotech Swiss AG

Completed

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase I Study Conducted in Healthy Volunteers

United Kingdom, South Africa, Poland
AIDS Malignancy Consortium
National Cancer Institute (NCI); Montefiore Medical Center; University of Arkansas and other collaborators

Completed

Cisplatin and Radiation Therapy in Treating Patients With HIV-Associated Locally Advanced Cervical Cancer

Acquired Immunodeficiency Syndrome | Cervical Cancer

South Africa, Zimbabwe
University of Cape Town

Completed

Hypertension And Surgery Study: Evaluating the Implementation of a Hypertension Guideline Protocol (HASS-2)

Hypertension | Metabolic Syndrome | Non-Compliance, Medication

South Africa
Alvotech Swiss AG

Active, not recruiting

Multicenter Study in Postmenopausal Women With Osteoporosis, ALVOBOND (ALVOBOND)

Osteoporosis, Postmenopausal

South Africa, Bulgaria, Czechia, Georgia, Poland
Antiva Biosciences

Recruiting

A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia

Australia, South Africa
Novartis Pharmaceuticals

Terminated

Myelodysplastic Syndrome (MDS) Gastrointestinal (GI) Tolerability Study (MACS1574)

Myelodysplastic Syndrome | Transfusional Iron Overload

Spain, France, Italy, South Africa
Walter Sisulu University
Medical University of Graz; Nelson Mandela Academic Hospital; Umtata General...

Not yet recruiting

Cardiometabolic Health of Children Exposed to Anti-retroviral Therapy (ART) in Utero (ARTMOMSBABES)

In Utero Drug Exposure

South Africa
Tarsa Therapeutics, Inc.

Completed

A Study Comparing Oral Calcitonin to Nasal Spray Calcitonin in Postmenopausal Osteoporotic Women (ORACAL)

Osteoporosis, Postmenopausal

United States, United Kingdom, Bulgaria, Hungary, Poland, South Africa
Hoffmann-La Roche

Completed

PRIOR Study - A Study of Ibandronate (Boniva) in Postmenopausal Women With Osteoporosis or Osteopenia

Postmenopausal Osteoporosis

United States
Wellcome Trust Liverpool Glasgow Centre for Global...
Professor David Lalloo; Professor Hamish Simpson; Professor William J Harrison; Professor Sithombo Maqungo

Unknown

HIV in Orthopaedic Skeletal Trauma Study (HOST)

Fracture Healing in HIV-positive Patients

South Africa
National and Kapodistrian University of Athens

Completed

Motor Control Exercise in Osteoporotic Women

Osteoporosis | Postmenopausal

Greece
Hoffmann-La Roche

Completed

A Study of Ibandronate (Bonviva) in Patients With Post-Menopausal Osteoporosis

Postmenopausal Osteoporosis

United States
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisition

HIV Infections | Bacterial Vaginosis

South Africa
Amgen

Completed

A Double-blind Study to Assess the Efficacy and Safety of Denosumab Produced by Two Different Processes in Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

United States, Denmark, Poland, Canada
University of Witwatersrand, South Africa

Unknown

A Comparison of Immediate Treatment of CIN1 With Cryotherapy and 12 Month Cytology Follow up in HIV Seropositive Women

Cervical Dysplasia

South Africa
Prisma Health-Upstate

Recruiting

Self-Administered 2-Hour Oral Glucose Tolerance Test

Gestational Diabetes | Gestational Diabetes Mellitus in Pregnancy | Postpartum Disorder

United States
Fresenius Kabi SwissBioSim GmbH

Completed

A Study to Evaluate the Efficacy, Pharmacodynamics, Safety, and Immunogenicity of FKS518 in Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

Hungary, Poland, Georgia, Bulgaria, Czechia, Estonia
Harriet Shezi Children's Clinic

Unknown

Dosing, Safety and Pharmacokinetic Profile of Rifabutin in Children Receiving Concomitant Treatment With Kaletra (RBT)

Children With Confirmed HIV Infection | Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose | Successfully Completed TB Treatment in the Past 2 to 6 Weeks of Enrollment

South Africa
Warner Chilcott

Completed

A Study of a 35 mg Delayed Release Formulation of Risedronate for Osteoporosis

Postmenopausal Osteoporosis

United States, Estonia, Hungary, Poland, Canada, France, Argentina, Belgium
Shire

Completed

TOP: Recombinant Human Parathyroid Hormone (ALX1-11) on Fracture Incidence in Women With Postmenopausal Osteoporosis

Osteoporosis

United States, Argentina, Canada, Brazil, Bulgaria, Israel, Mexico, Romania, Russian Federation
Sanofi Pasteur, a Sanofi Company

Completed

DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants

Hepatitis B | Pertussis | Tetanus | Diphtheria | Polio | Human Immunodeficiency Virus Infection

South Africa
University of Witwatersrand, South Africa

Completed

Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women (VICAR2)

Cervical Intraepithelial Neoplasia

South Africa
Amgen

Completed

Efficacy and Safety of Romosozumab Treatment in Postmenopausal Women With Osteoporosis (FRAME)

Postmenopausal Osteoporosis

United States, Canada, Denmark, Germany, Belgium, Colombia, Czechia, Japan, Mexico, Poland, Switzerland, Hungary, Spain, Australia, Romania, United Kingdom, India, Argentina, Brazil, Dominican Republic, Estonia, Latvia, Lithuania, New...
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir (ORCHID)

Obesity | HIV | Maternal Obesity During Childbirth | Maternal Obesity Complicating Pregnancy | Obesity, Infant

South Africa
University of California, Los Angeles

Active, not recruiting

Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)

Nutrition Disorders | HIV | Fetal Alcohol Syndrome

South Africa
Harokopio University

Completed

The Effect of Mastiha Oil in Metabolic Syndrome

Metabolic Syndrome

Greece
BioCryst Pharmaceuticals

Recruiting

Dose Escalation of BCX10013 in Subjects With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

South Africa, Malaysia
Hoffmann-La Roche

Completed

A Study of Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis Who Have Received Previous Bonviva Treatment

Post-Menopausal Osteoporosis

Spain, South Africa, Germany, Mexico, Italy, Belgium, United States, Poland, Denmark, Hungary, Czech Republic, France, Norway, United Kingdom, Australia
Wayne State University
Columbia University; University of Cape Town

Recruiting

RCT of Prenatal Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure

Fetal Alcohol Spectrum Disorders | Fetal Alcohol Syndrome

South Africa
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Enrolling by invitation

"Adding DNA-test for Screening of HLA-DQ2 and DQ8 to Improve Early Diagnosis of Celiac Disease" (GLUTEN-GEN)

Celiac Disease in Children

Netherlands
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Procter and Gamble

Completed

Bisphosphonate Action on the Appendicular Skeleton: Evidence for Differential Effects

Post-menopausal Osteoporosis

United Kingdom
Harokopio University
University of Thessaly; University of Ioannina; University of Patras; CitiesNet; ... and other collaborators

Recruiting

Lifestyle-related Early Detection and Intervention for Older Adults & Elderly at Risk for Metabolic Syndrome (GATEKEEPER)

Metabolic Syndrome

Greece
Radius Health, Inc.

Completed

Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

United States, Poland, Denmark, Hungary, Puerto Rico
Sanofi
Procter and Gamble

Completed

OPTAMISE: Clinical Effectiveness of Teriparatide After Alendronate or Risedronate Therapy in Osteoporotic Postmenopausal Women

Osteoporosis, Postmenopausal

United States, Netherlands, Australia, Belgium, Canada, France, United Kingdom
Hoffmann-La Roche

Completed

A Study of Ibandronate (Boniva) to Evaluate Satisfaction in Women With Post-Menopausal Osteoporosis or Osteopenia

Postmenopausal Osteoporosis

United States
Novartis Pharmaceuticals

Terminated

Extension to a Randomized, Double-blind, Placebo Controlled Study of LCQ908 in Subjects With Familial Chylomicronemia Syndrome.

Familial Chylomicronemia Syndrome (FCS) (HLP Type I)

South Africa, Germany, United Kingdom, France, United States, Canada, Netherlands
Western Sydney Local Health District

Completed

Metformin in Preventing Androgen Deprivation Therapy Induced Insulin Resistance and Metabolic Syndrome (MVENT)

Metabolic Syndrome | Hypercholesterolemia

Australia
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Acute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditions

South Africa
Warner Chilcott

Completed

Effect of Stopping Risedronate After Long Term Treatment on Bone Turnover

Postmenopausal Women With Osteoporosis

Spain, Australia, Belgium, Denmark, Finland, Italy, Poland, Sweden
Novartis Pharmaceuticals

Completed

A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome

Familial Chylomicronemia Syndrome (FCS)

South Africa, Spain, France, Germany, United Kingdom, United States, Canada, Netherlands
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.

Cervical Cancer | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | Cervical Dysplasia | HSIL of Cervix | High-Grade Cervical Intraepithelial Neoplasia | HIV Negative | CIN - Cervical Intraepithelial Neoplasia | Cervical Neoplasm

South Africa
Hasanuddin University

Recruiting

Nusantara Diet (Low Calorie and Low Sodium) for Metabolic Syndrome

Diabetes | Metabolic Syndrome | Hyperlipidemias

Indonesia
Eli Lilly and Company

Completed

Study Comparing Arzoxifene With Raloxifene in Women After Menopause With Osteoporosis

Osteoporosis, Postmenopausal

Spain, United States, Taiwan, Italy, Argentina, Canada, France, Australia
BioCryst Pharmaceuticals

Terminated

A Long Term Safety Study of BCX9930 in Subjects With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria | PNH

United Kingdom, Austria, South Africa
Hoffmann-La Roche

Completed

DIVA Study - A Study of Different Regimens of Intravenous Administration of Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis

Post Menopausal Osteoporosis

Spain, South Africa, Germany, Mexico, United States, Canada, France, United Kingdom, Italy, Belgium, Australia, Poland, Denmark, Hungary, Czech Republic, Norway
Birjand University of Medical Sciences

Completed

Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syndrome

Hyperglycemia | Metabolic Syndrome | Hypercholesterolemia | Hypertriglyceridemia

Iran, Islamic Republic of

Clinical Trials on Metabolic Syndrome in Postmenopausal Females in South Africa

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