Clinical Trials on Metabolic Side Effects of Drugs and Substances

Total 11318 results

Beijing Ditan Hospital

Unknown

Establishment of Drug-induced Liver Injury Databases and Application of Circulating microRNA(miRNA)

Drug-induced Liver Injury

China
Philippe Bégin
The Hospital for Sick Children; Centre de recherche du Centre hospitalier universitaire... and other collaborators

Recruiting

Omalizumab to Accelerate a Symptom-driven Multi-food OIT (BOOM)

Immunotherapy | Physiological Effects of Drugs | Food IgE-mediated Allergy | Omalizumab

Canada
Universitaire Ziekenhuizen KU Leuven

Completed

Exploratory Propofol Dose Finding Study In Neonates (NEOPROP)

Adverse Reaction to Drug | Neonatal Disorder

Belgium
Taipei Veterans General Hospital, Taiwan

Unknown

Cholestatic Drug-induced Liver Injury (DILI)

Hepatitis, Toxic

Taiwan
Li Yang

Recruiting

Glucocorticosteroid Therapy on Drug-induced Liver Injury: a Prospective Non-randomized Concurrent Control Trial

Drug-induced Liver Injury

China
Drug Induced Liver Disease Study Group

Unknown

A Prospective Cohort Study on Drug-induced Liver Injury in China（DILI-P） (DILI-P)

Drug-induced Liver Injury

China
GlaxoSmithKline

Completed

Rechallenge, Potential Drug Induced Liver Injury (Kaiser)

Drug-induced Liver Injury
Shanghai Zhongshan Hospital

Unknown

Antidepressant Monotherapy on Depressive and Anxiety Symptom in Chinese Patients

Anxiety Disorders and Symptoms | Adverse Drug Reaction

China
Jianxiang Wang
Xian-Janssen Pharmaceutical Ltd.

Unknown

Therapeutic Effect and Safety Study of Decitabine in Elderly Acute Myeloid Leukemia Patients

Untreated Adult Acute Myeloid Leukemia | Effect of Drugs | Drug Safety
Duke University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Drug-Induced Liver Injury (DILI) Network Retrospective (ILIAD)

Drug Induced Liver Injury

United States
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Runzao Zhiyang Capsule.

Drug-Induced Liver Injury

China
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Xianlin Gubao Capsule.

Drug-Induced Liver Injury

China
Drug Induced Liver Disease Study Group
Unimed Scientific Inc.

Completed

A Retrospective Study on Drug Induced Liver Injury in China (DILI-R)

Drug-Induced Liver Injury

China
University of Chicago

Completed

Behavior Brain Responses (BBR)

Alcohol Drinking | Drinking Behavior | Physiological Effects of Drugs | Central Nervous System Depression

United States
Institute of Liver and Biliary Sciences, India

Terminated

Efficacy of N-acetylcysteine With or Without Steroids in Drug Induced Liver Injury

Drug Induced Liver Injury

India
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Yangxue Shengfa Capsule.

Drug-Induced Liver Injury

China
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Xianlin Gubao Granule

Drug-Induced Liver Injury

China
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Xianlin Gubao Pill.

Drug-Induced Liver Injury

China
The Republican Research and Practical Center for...

Unknown

Improved Basophil Activation Test (BAT) in the Diagnostics of Drug Allergy

Antibiotic Allergy | Drug Allergy | NSAID-Induced Anaphylactoid Reaction

Belarus
University Hospital, Toulouse

Unknown

Voluntary Drug Poisoning by Psychoactive Molecules: Identify Cognitive Markers (IMG-COG)

Suicide | Drug Poisoning

France
University College Cork

Unknown

Discontinuation of Long-term Medications in Older People Entering Nursing Home Care (STOPPFrail)

Frail Elderly Syndrome | Drug-Related Side Effects and Adverse Reactions | Polypharmacy | Inappropriate Prescribing

Ireland
University of North Carolina, Chapel Hill

Completed

Identifying Changes in Blood (Potential Biomarkers) in Individuals With Drug-Induced Liver Injury

Drug Induced Liver Injury

United States
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Zhuanggu Guanjie Pill

Drug-Induced Liver Injury

China
University Hospital, Montpellier

Completed

Multiple Drug Hypersensitivity Syndrome (MDH)

Drug Allergy

France
Beni-Suef University

Unknown

Comparative Effect of Transforaminal Injection of Magnesium Sulphate Versus Ozone Therapy on Oxidative Stress Biomarkers in Lumbar Disc Related Radicular Pain

Effect of Drug

Egypt
Janssen Korea, Ltd., Korea

Completed

A Study to Evaluate Treatment Adherence in Schizophrenia With Long Acting Risperidone Microspheres (e-STAR)

Mental Disorders | Schizophrenia | Tranquilizing Agents | Therapeutic Uses | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

Efficacy and Safety Study of Magnesium Isoglycyrrhizinate Injection in Subjects With Acute Drug-induced Liver Injury

Drug-Induced Liver Injury

China
Bayer
RTI Health Solutions

Completed

Risk of Acute Liver Injury in Users of Antimicrobials

Drug-Induced Liver Injury

United States
Zhejiang Cancer Hospital

Completed

Clinical Application Value of Remazolam Combined With Sugammadex Sodium in Anesthesia for Endotracheal Surgery Under Bronchoscopy

Endobronchial Metastases | Bronchoesophageal Fistula | General Anesthetic Drug Adverse Reaction

China
Johns Hopkins University

Withdrawn

Prevention of Drug Rash From Certain Cancer Therapies Using Tretinoin Cream

Medication Reaction
National Heart Centre Singapore
National University Hospital, Singapore

Unknown

SAPhIRE Statin Adverse Drug Reaction (STATIN)

Myopathy

Singapore
Beijing Ditan Hospital

Unknown

Correlative Cohort Study on the Clinical Features and Prognosis of Drug-induced Liver Injury

Drug-induced Liver Injury

China
Dow University of Health Sciences

Not yet recruiting

Comparison of the Anti-Inflammatory Efficacy of Preemptive Dexamethasone and Etoricoxib

Effect of Drug
Ain Shams University

Completed

Efficacy of Trypsin-Chymotrypsin On Post-operative Pain After Single Visit Root Canal Treatment

Effect of Drug

Egypt
Aarhus University Hospital
Rigshospitalet, Denmark; Herlev Hospital

Recruiting

TDM for Optimized Outcome in Patients With mRCC.

Kidney Cancer | Renal Cell Carcinoma Metastatic | Drug Toxicity | Drug Side Effect | Drug Mechanism

Denmark
POLYSAN Scientific & Technological Pharmaceutical...

Recruiting

Remaxol® in Patients With Drug-induced Liver Injuries During Cancer Chemotherapy

Cancer | Drug Induced Liver Injury

Russian Federation
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Massachusetts General Hospital; Guangdong Provincial People's Hospital

Completed

Neoadjuvant Chemotherapy or Chemoradiotherapy in Resectable Oesophageal Carcinoma（NewEC Study）

Chemotherapy Effect | Safety Issues | Radiotherapy Side Effect | Effect of Drugs | Oesophageal Carcinoma

China, United States
Xingui Dai

Unknown

A Warmer Temperature Decrease Propofol Injection Pain

Injection Site Irritation | Temperature Change, Body | Propofol Syndrome

China
University of Nottingham
National Institute for Health Research, United Kingdom; International Stem...

Completed

Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors

Quality of Life | Cancer | Hearing Loss, Sensorineural | Tinnitus, Subjective | Late Effect

United Kingdom
Dar El Oyoun Hospital

Unknown

Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in Phacoemulsification

Cataract | Adverse Drug Event | Mydriasis

Egypt
Peking University Third Hospital

Unknown

Risk Assessment Model of Trastuzumab-related Cardiotoxicity in Breast Cancer Patients

Breast Cancer | Cardiac Toxicity | Antitumor Drugs

China
NYU Langone Health
National Cancer Institute (NCI)

Completed

Chemotherapy and Amifostine in Treating Patients With Recurrent or Refractory Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Drug/Agent Toxicity by Tissue/Organ

United States
Oncologia Medica dell'Ospedale Fatebenefratelli
Mario Negri Institute for Pharmacological Research

Completed

PAINTER: Polymorphism And INcidence of Toxicity in ERibulin Treatment

Metastatic Breast Cancer | Toxicity | Neurotoxicity | Adverse Drug Event | Drug Toxicity

Italy
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (DACAT)

Drug Hypersensitivity | Drug-Induced Anaphylaxis | Antibiotic Allergy | Drug Allergy | Beta Lactam Adverse Reaction | Cephalosporin Allergy | Cephalosporin Reaction

United States
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy and Safety of Plasma Exchange Compared to Standard Medical Therapy in Patients With Severe Drug Induced Liver Injury With or Without Underlying Chronic Liver Disease.

Chronic Liver Disease

India
University Hospital, Rouen
Ligue contre le cancer, France

Terminated

Tc-99m Renography and Cisplatin-induced Nephrotoxicity

Cancer | Kidney Failure | Drug Toxicity
Tianjin Medical University Cancer Institute and...

Recruiting

Bicyclol in the Treatment of Antineoplastic Drug-induced Liver Injury.

Drug-Induced Acute Liver Injury

China
The First Affiliated Hospital with Nanjing Medical...
University of Colorado, Denver; Nanjing Medical University; Beijing Genomics...

Recruiting

Screening of Susceptibility Genes for APAP Induced Drug Induced LIver Injury in ChiNese Population: a Case-control Study (PAIN)

Pharmacogenetics | Drug-Induced Liver Injury | Acetaminophen | China

China
Assaf-Harofeh Medical Center

Unknown

Exploratory Study on the Use of Pregabalin for the Treatment of Taxol Related Arthralgia-Myalgia

Pain | Breast Cancer | Taxane | Drug-related Side Effects and Adverse Reactions

Israel
Rambam Health Care Campus

Completed

The Heart Failure Diuresis Efficacy Comparison (DEA-HF) Study (DEA-HF)

Chronic Heart Failure | Congestive Heart Failure | Diuretics Drug Reactions

Israel

Clinical Trials on Metabolic Side Effects of Drugs and Substances

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