Clinical Trials on Metabolism and Elimination

Total 410713 results

Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Gemcitabine Plus Pemetrexed Disodium in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Baltimore VA Medical Center
University of Maryland

Unknown

Exercise for Stable Myasthenia Gravis

Myasthenia Gravis

United States
Saint Michael's Medical Center

Completed

Sofosbuvir, Ribavirin, for the Treatment of Chronic Hepatitis C Virus Genotype 1 in HIV-Coinfected Patients Receiving Fixed Dose Co-formulation Emtricitabine/ Tenofovir/Cobicistat/Elvitegravir: A Pilot Study

HIV Infection | Hepatitis C Infection

United States
SCRI Development Innovations, LLC
Infinity Pharmaceuticals, Inc.

Completed

Study of IPI-145 in Combination With Rituximab or Bendamustine/Rituximab in Hematologic Malignancies

Lymphoma | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | T-cell Lymphoma

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Celgene Corporation

Terminated

Lenalidomide as Chemoprevention in Treating Patients With High-Risk, Early-Stage B-Cell Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | B-cell Chronic Lymphocytic Leukemia | Stage 0 Chronic Lymphocytic Leukemia | Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia

United States
The Cleveland Clinic
University Hospitals Cleveland Medical Center

Completed

Autologous Mesenchymal Stem Cell (MSC) Transplantation in MS

Relapsing-Remitting Multiple Sclerosis | Secondary Progressive Multiple Sclerosis | Progressive Relapsing Multiple Sclerosis

United States
Tel-Aviv Sourasky Medical Center

Unknown

Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study (ITMTXPMS)

To Evaluate the Effect of Therapy With IT MTX on the Disease Course of Patients With Progressive MS
Acibadem University
Acibadem Atakent University Hospital

Unknown

The Role of Indocyanine Green (ICG) Fluorescence Imaging on Anastomotic Leak in Robotic Colorectal Surgery

Rectal Neoplasms | Inflammatory Bowel Disease | Colon Neoplasms | Diverticular Disease

Turkey
Beijing 302 Hospital

Unknown

A Clinical Evaluation on Traditional Chinese Medicine Diagnosis and Treatment Program Blocking and Reversing Hepatitis B-related Liver Fibrosis - a Randomized, Controlled, Double-blind, Multi-center Clinical Trial

Chronic Hepatitis B | Liver Fibrosis

China
Anna Cruceta

Completed

HIV Patients With Chronic Hepatitis C Genotype 1 Infection Who Failed Previously to Peginterferon /Ribavirin (BOC-HIV)

HIV Infections | Hepatitis C | COINFECTION

Spain
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy, Combination Chemotherapy, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Pfizer

Completed

Immunogenicity and Safety Study of a Third Vaccination With FSME-IMMUN 0.5 mL in Subjects Previously Vaccinated According to a Rapid Immunization Schedule (Follow-up to Study 225)

Encephalitis, Tick-borne

Belgium
Pfizer

Completed

Study to Investigate the Seropersistence of TBE Virus Antibodies Approx. 3 Years After a Booster Vaccination With FSME-IMMUN 0.25 mL JUNIOR in Children

Encephalitis, Tick-borne

Austria
Pfizer

Completed

Immunogenicity and Safety Study of a Rapid Immunization Schedule With FSME-IMMUN 0.5 mL in Healthy Adults Aged 16 - 65 Years

Encephalitis, Tick-borne

Belgium
Pfizer

Completed

Investigation of the Seropersistence of TBE Antibodies and the Booster Response to FSME-IMMUN 0.5 ml in Adults Aged 18 - 67 Years

Tick-borne Encephalitis

Poland
International Extranodal Lymphoma Study Group (IELSG)

Withdrawn

A Phase I Study of Intrathecal Rituximab in Patients With Lymphomatous Meningitis

Lymphoma, B Cell
FDA Office of Orphan Products Development
Duke University

Completed

Mycophenolate Mofetil in Myasthenia Gravis

Myasthenia Gravis
Astellas Pharma Inc

Completed

FK506 Phase 3 Study: a Study for Steroid Non-resistant Myasthenia Gravis (MG) Patients

Myasthenia Gravis

Japan
Nanfang Hospital of Southern Medical University
Major Science and Technology Special Project of China Eleventh Five-year

Unknown

Efficacy Optimizing Extension Study of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy (Dragon-Ex)

Chronic Hepatitis B | Inadequate Response | Nucleos(t)Ide Analogues Treatment

China
University Hospital, Strasbourg, France

Unknown

Clinical Investigation of Erlotinib as an HCV Entry Inhibitor

Chronic Hepatitis C Infection | HCV Genotype 1b

France
Prof. Dr. Alice Schmidt

Unknown

Hepatitis C in Renal Transplant Recipients

Renal Transplantation | Chronic Hepatitis C-virus Infection

Austria
Yonsei University
Bristol-Myers Squibb; Seoul St. Mary's Hospital; The Catholic University of Korea

Unknown

Entecavir Plus Tenofovir Combination in Subjects With Multi-drug Resistant Chronic Hepatitis B Virus Infection

Chronic Hepatitis B
Gilead Sciences

Completed

A Study Evaluating GS-9620 in Virologically Suppressed Subjects With Chronic Hepatitis B Virus Infection

Hepatitis B

Korea, Republic of, United States, Canada, Australia, New Zealand
Sun Yat-sen University
Eli Lilly and Company; Hoffmann-La Roche

Unknown

Avastin+ GemAOD As First-Line Treatment in NK/T Cell Lymphoma

Extranodal NK/T-cell Lymphoma, Nasal Type

China
Fudan University

Terminated

Radiotherapy Alone Versus Concurrent Chemoradiation in Low Risk NK/T-cell Lymphoma

Extranodal NK/T-cell Lymphoma, Nasal Type

China
National Cancer Institute (NCI)

Completed

Imatinib Mesylate in Treating Patients With Stage IV Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Peter Bushunow MD
Novartis Pharmaceuticals

Terminated

Zometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung Cancer (ZAP)

Non Small Cell Lung Cancer | Malignant Pleural Effusion

United States
Shenzhen Beike Bio-Technology Co., Ltd.
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical... and other collaborators

Unknown

Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica

Progressive Multiple Sclerosis | Neuromyelitis Optica.

China
University Hospital, Strasbourg, France

Unknown

"Real-life" Cohort of Patients With Chronic Hepatitis B Virus Infection

Hepatitis B

France
Muscular Dystrophy Association

Unknown

A Pilot Study of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Generalized Myasthenia Gravis

Myasthenia Gravis

United States
King's College Hospital NHS Trust

Completed

Pilot Study of Combination Therapy With CHOP-Zenapax (CHOP-daclizumab)

HTLV-I Associated Adult T-cell Leukaemia/Lymphoma (ATLL)

United Kingdom
National Pediatric Neuroinflammation Organization...
Genentech, Inc.

Completed

Effectiveness of Rituximab in Pediatric OMS Patients.

Ataxia | Myoclonus | Opsoclonus-myoclonus Syndrome | Opsoclonus

United States
Catalysis SL

Completed

Efficacy and Safety of Viusid in Patients With Hepatic Cirrhosis Secondary to Hepatitis C Virus Infection.

Cirrhosis | Chronic Hepatitis C

Cuba
University Health Network, Toronto
Grifols Therapeutics LLC

Completed

Intravenous Immunoglobulin and Plasma Exchange in Myasthenia Gravis

Myasthenia Gravid

Canada
Bristol-Myers Squibb

Completed

Comparative Trial of Entecavir Versus Adefovir in the Treatment of Chronic Hepatitis B Infection

Hepatitis B | Chronic Disease

United States, Canada, Indonesia, Singapore, Philippines, Taiwan, Hong Kong, Thailand
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Rebeccamycin Analogue in Treating Patients With Advanced Liver and/or Biliary Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Sun Yat-sen University

Completed

Observe Change of Endotoxaemia and Related Mediators in Patients With Chronic Hepatitis B Virus (HBV) Infection (OCEHBV)

Hepatitis B, Chronic

China
Bristol-Myers Squibb

Withdrawn

MDX-060 in Patients With Relapsed or Refractory Classic Systemic or Primary Cutaneous Anaplastic Large Cell Lymphoma

Lymphoma, Large-Cell

United States, France
National Taiwan University Hospital

Completed

Prediction of Hepatic Fibrosis in Patients With Chronic Hepatitis C by Biochemical and Duplex Doppler Indices

Cirrhosis | Chronic Hepatitis C | Hepatic Fibrosis

Taiwan
National Institute of Neurological Disorders and...

Completed

Direct Injection of Alcohol for the Treatment of Spinal Tumors

Neoplasm Metastasis | Hemangioma | Spinal Neoplasm

United States
Spectrum Pharmaceuticals, Inc

Completed

Elsamitrucin (SPI 28090) for Relapsed or Refractory Non-Hodgkin's Lymphoma

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

United States
Georgetown University

Completed

Urban Environmental Exposures and Childhood Cancer

Acute Lymphoblastic Leukemia | Brain Cancer

United States
Calliditas Therapeutics AB

Completed

Efficacy and Safety of Xepol (Human Immunoglobulin) in Subjects With Post-Polio Syndrome (PPS)

Post Polio Syndrome, PPS

Sweden
University Health Network, Toronto

Completed

Intravenous Immune Globulin Treatment Compared to Placebo in Patients With Myasthenia Gravis

Myasthenia Gravis

Canada
SmithKline Beecham

Completed

Safety and Effectiveness of Topotecan HCl to Treat HIV-Infected Patients With AIDS-Related Progressive Multifocal Leukoencephalopathy (PML)

HIV Infections | Leukoencephalopathy, Progressive Multifocal

United States
ZS Associates
University of California, San Francisco

Recruiting

Feasibility of Engaging and Capturing Undiagnosed Myasthenia Gravis Participants Through a Social Media Campaign Paired With a Self-moderated Assessment

Neuromuscular Diseases | Neuromuscular Manifestations | Myasthenia Gravis

United States
Liaoning Chengda Biotechnology CO., LTD

Recruiting

Safety Observation of the Japanese Encephalitis Vaccine Given With a Primary Immunization

Japanese Encephalitis

China
Sanofi

Recruiting

A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

Relapsing Multiple Sclerosis | Secondary Progressive Multiple Sclerosis | Progressive Relapsing Multiple Sclerosis

Belgium
H. Lee Moffitt Cancer Center and Research Institute
BeiGene, Ltd.

Recruiting

Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas

Follicular Lymphoma | Marginal Zone Lymphoma | B-Cell Lymphoma

United States
King Chulalongkorn Memorial Hospital
Chulalongkorn University

Not yet recruiting

The Efficacy of Aerobic Exercise Training on Autonomic Nervous System and Endothelial Function in Patients With Compensated Cirrhosis

Physical Activity | Cirrhosis | Sarcopenia | Heart Rate Variability | Physical Functional Performance | Lifestyle Modification | Autonomic Dysfunction | Endothelial Function | Autonomic Nervous System | Aerobic Exercises | Flow Mediated Dilation

Thailand

Clinical Trials on Metabolism and Elimination

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Taiwan

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Rare Diseases

Drug Interventions

Dietary Supplements

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