Clinical Trials on Metastatic Colorectal Cancers

Total 55667 results

Jules Bordet Institute

Completed

Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers (MOMENTUM1)

Metastatic Colorectal Cancers | Metastatic Gastric Cancers | Metastatic Oesophageal Cancers | Metastatic Pancreatic Cancers | Metastatic Biliary Cancers | Metastatic Breast Cancers

Belgium
Institut de Cancérologie de la Loire
Saint-Louis Hospital, Paris, France; Gustave Roussy, Cancer Campus, Grand Paris

Withdrawn

Phase II Trial Assessing the Efficacy of Immuno-Radiation Abscopal Effect in Patients With Metastatic Cancers (IRAM)

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Head and Neck Cancer

France
Grupo Espanol Multidisciplinario del Cancer Digestivo

Recruiting

Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease (LIVERPEARL)

Colorectal Cancer Metastatic | Liver Metastasis Colon Cancer

Spain
Fundación de Investigación Biomédica - Hospital...
Marcello Di Martino

Completed

Chemotherapy for Resectable Colorectal Liver Metastases

Metastatic Colorectal Cancer | Metastatic Liver Cancer

Spain, United Kingdom, France
Samsung Medical Center

Completed

Clinical Sequencing Project for Metastatic Cancer Patients for Personalized Cancer Clinic.

Colorectal Cancer

Korea, Republic of
Centre Hospitalier Universitaire de Nice

Completed

Circulating Tumor Cells and Neutrophils Count for Colorectal Metastatic Cancer

Metastatic Colorectal Cancer

France
Institut Investigacio Sanitaria Pere Virgili
Institut Català d'Oncologia; Hospital Universitario Ramon y Cajal; Hospital Arnau... and other collaborators

Recruiting

The Impact of Radiotherapy on Oligometastatic Cancer

Metastatic Colorectal Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastasis | Metastatic Prostate Cancer

Spain
Chandrikha Chandrasekharan
AstraZeneca; Biocompatibles UK Ltd

Suspended

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer (iRE-C)

Metastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon Cancer

United States
Duke Cancer Institute
National Cancer Institute (NCI)

Completed

Immunotherapy in Treating Patients With Resected Liver Metastases From Colon Cancer

Colorectal Cancer | Metastatic Cancer

United States
GERCOR - Multidisciplinary Oncology Cooperative...
Bristol-Myers Squibb

Active, not recruiting

iRECIST Evaluation's Relevance for DCR in MMR/MSI Metastatic Colorectal Cancer Patients on Nivolumab and Ipilimumab (NIPICOL)

Metastatic Cancer Colorectal

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Monalizumab and MEDI5752 in Patients With MSI and/or dMMR Metastatic Cancer (MONAMI)

MSI | dMMR Colorectal Cancer

France
University Hospital, Linkoeping
Sahlgrenska University Hospital, Sweden; Medical Research Council of Southeast...

Recruiting

Evaluation of Tumour Growth and Oncological Treatment in Patients With CRLM Using Zebra Fish Embryo Model (CRLM-Z)

Colorectal Cancer Metastatic | Chemotherapy Effect | Tumour Metastasis | Tumor Growth

Sweden
Orion Biotechnology Polska Sp. z o.o.

Not yet recruiting

Study of OB-002 in Patients With Refractory Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Cancer | Metastatic Breast Cancer | Metastatic Urothelial Carcinoma | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer
UNICANCER

Completed

EXPRESS: EXcePtional RESponSe - Exceptional and Unexpected Response to Targeted Therapies (EXPRESS)

Metastatic Cancers

France
Mayo Clinic

Completed

A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic... and other conditions

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Patients With Colon Cancer That Has Spread to the Liver

Colorectal Cancer | Metastatic Cancer

United States
University Hospital, Ghent

Completed

The Inflammatory Response to Stress and Angiogenesis in Liver Resection

Colorectal Cancer | Metastatic Cancer | Liver Metastases | Liver Cancer
Grupo Espanol Multidisciplinario del Cancer Digestivo
Amgen; Pivotal S.L.

Completed

FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status (OPALO)

Neoplasm Metastasis | Colorectal Neoplasms | Colorectal Cancer Metastatic | Colorectal Carcinoma

Spain
University of Manchester
The Christie NHS Foundation Trust; University Hospital Birmingham; Hampshire... and other collaborators

Completed

Development of an IDEAL Framework to Standardise Cytoreductive Surgery for Colorectal Peritoneal Metastases (IDEAL-PM)

Colorectal Cancer Metastatic | Peritoneal Metastases
Abramson Cancer Center of the University of Pennsylvania

Completed

RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers

Metastatic Cancers

United States
British Columbia Cancer Agency
BC Cancer Foundation

Recruiting

Personalized Oncogenomics (POG) Program of British Columbia

Advanced Cancers | Metastatic Cancers | Cancers That Cannot be Treated With Curative Intent

Canada
Region Skane

Recruiting

On-treatment Biomarkers in Metastatic Colorectal Cancer for Life (On-CALL)

Metastatic Colorectal Cancer | Lung Metastases | Chemotherapy Effect | Peritoneal Metastases | Liver Metastasis Colon Cancer

Sweden
Amal Therapeutics
Boehringer Ingelheim

Active, not recruiting

Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01)

Metastatic Colorectal Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | MSS

United States, Belgium, Switzerland, Germany
M.D. Anderson Cancer Center

Recruiting

Combination Therapy for Cancer Related Fatigue in Patients With Metastatic Cancers

Fatigue | Metastatic Cancers

United States
Zhejiang Cancer Hospital

Not yet recruiting

Clinical Study of Short-course Radiotherapy Followed by Fruquintinib Plus Sintilimab vs Bevacizumab Plus Capecitabine as First Line Treatment in Advanced mCRC

Metastatic Colorectal Cancer | Metastatic Colorectal Adenocarcinoma | CRC

China
Emory University
Bristol-Myers Squibb; National Cancer Institute (NCI); National Institutes of...

Active, not recruiting

Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

Colorectal Cancer Metastatic | Colorectal Adenocarcinoma | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Refractory Colorectal Carcinoma | Metastatic Microsatellite Stable Colorectal Carcinoma | Stage IVC Colorectal Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

Metastatic Malignant Neoplasm in the Liver | Advanced Malignant Neoplasm | Refractory Malignant Neoplasm | Colorectal Carcinoma Metastatic in the Liver

United States
Ottawa Hospital Research Institute
Sanofi; Hoffmann-La Roche

Withdrawn

IXO+A in mCRC With Liver-only Metastases

Metastatic Colorectal Cancer

Canada
Hutchison Medipharma Limited

Active, not recruiting

A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer (FRESCO-2)

Metastatic Colorectal Cancer | Metastatic Colon Cancer

United States, Spain, Japan, Australia, Austria, Belgium, Czechia, Estonia, France, Germany, Hungary, Italy, Poland, United Kingdom
University of Manchester
Manchester University NHS Foundation Trust; The Christie NHS Foundation Trust; Perspect... and other collaborators

Unknown

Colorectal Liver Metastases: Novel Assessment Tools for Technical Resectability (CoNoR)

Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Cancer Metastatic

United Kingdom
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer

Metastatic Pancreatic Adenocarcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Gastroesophageal Junction Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Malignant... and other conditions

United States
University Medical Center Groningen

Recruiting

Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer (GIMICC)

Colorectal Cancer Metastatic

Netherlands
Sun Yat-sen University

Unknown

The Gene Profiles of Primary and Heterogeneous Metastases of Colorectal Cancer

Metastatic Colorectal Cancer

China
Alethia Biotherapeutics

Recruiting

Sotevtamab (AB-16B5) Combined With FOLFOX as Neoadjuvant Treatment Prior to Resection of Colorectal Cancer Liver Metastasis (EGIA-003)

Metastatic Colorectal Cancer

Canada
Shengjing Hospital

Recruiting

MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases

Metastatic Colorectal Cancer

China
Vastra Gotaland Region
Isofol Medical AB

Unknown

Modelle 001, TS-inhibition in Colorectal Liver Metastases Comparing Arfolitixorin and Calciumfolinate

Metastatic Colorectal Cancer

Sweden
University Hospital, Tours

Completed

Evaluation of Contrast-enhanced Ultrasound Imaging for the Early Estimate of Bevacizumab Effect on Colorectal Cancer Liver Metastases

Metastatic Colorectal Cancer

France
Array Biopharma, now a wholly owned subsidiary...

Completed

A Study of ARRY-438162 (MEK162) in Patients With Advanced Cancer

Metastatic Colorectal Cancer | Advanced Solid Tumors | Advanced or Metastatic Biliary Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Liver Surgery and Chemotherapy in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery and Lung Metastases That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Metastatic Malignant Neoplasm in the Lung | Resectable Colorectal Carcinoma

United States
European Organisation for Research and Treatment...
Sanofi

Withdrawn

Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases (BOS3)

Colorectal Cancer Metastatic | Liver Metastases | KRAS Mutated Colorectal Cancer
European Organisation for Research and Treatment...
Roche Pharma AG; Amgen

Terminated

Efficacy of FOLFOX Alone, FOLFOX Plus Bevacizumab and FOLFOX Plus Panitumumab in Patients With Resectable Liver Metastases (BOS2)

Colorectal Cancer Metastatic | Liver Metastases | KRAS Wild Type Colorectal Cancer

France, Belgium, Austria, Netherlands, Spain, Switzerland
Dana-Farber Cancer Institute
American Cancer Society, Inc.

Not yet recruiting

Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

Metastatic Colorectal Cancer | Colorectal Cancer | Metastatic Colon Cancer

United States
University Health Network, Toronto
British Columbia Cancer Agency; Terry Fox Research Institute

Active, not recruiting

Comprehensive Genomic Profiling of Colorectal Cancer Patients With Isolated Liver Metastases to Understand Response & Resistance to Cancer Therapy (COMPARISON)

Colorectal Cancer | Colorectal Cancer Metastatic | Hepatic Metastases

Canada
Symphogen A/S

Withdrawn

Sym004 Versus TAS-102 in Patients With mCRC

Carcinoma | Metastatic Colorectal Cancer | Colorectal Cancer Metastatic
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study of the Intra-patient Variability of the Quantitative Parameters of Tumor Perfusion Evaluated With Ultrasound Contrast (VARIA-DCE-US)

GIST Metastatic Cancer | Breast Metastatic Cancer | Kidney Metastatic Cancer | Colon Metastatic Cancer | Rectal Metastatic Cancer

France
Amgen

Completed

SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial

Cancer | Metastatic Colorectal Cancer | Colorectal Cancer | Rectal Cancer | Metastatic Cancer | Colon Cancer
Symphogen A/S

Terminated

Sym004 Versus Futuximab or Modotuximab in Patients With mCRC

Carcinoma | Metastatic Colorectal Cancer | Colorectal Cancer Metastatic

United States, Spain, Germany, Italy
Central European Society for Anticancer Drug Research

Completed

FOLFIRI and Sunitinib in Metastatic Colorectal Cancer

Metastatic Colorectal Cancer | Liver Metastases

Germany
Amsterdam UMC, location VUmc

Recruiting

COLLISION XL: Unresectable Colorectal Liver Metastases (3-5cm): Stereotactic Body Radiotherapy vs. Microwave Ablation (COLLISION-XL)

Colorectal Cancer Metastatic | Liver Metastasis Colon Cancer

Netherlands
University Health Network, Toronto

Recruiting

In Vivo Lung Perfusion (IVLP) for Colorectal Cancer Metastatic to Lung

Colorectal Cancer | Lung Metastases | Colorectal Cancer Metastatic

Canada

Clinical Trials on Metastatic Colorectal Cancers

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