Clinical Trials on Metastatic Malignant Neoplasm

Total 107347 results

Washington University School of Medicine

Recruiting

Palliative Spatially Fractionated (GRID) Radiotherapy Using Intensity Modulated Proton Therapy

Metastatic Cancer | Unresectable Solid Tumor

United States
The Belgian Society of Medical Oncology
Roche Pharma AG; Foundation Medicine; Sciensano

Recruiting

A Study to Examine the Value of Broad Agnostic Next Generation Sequencing (NGS) Panel Testing Versus Reimbursed Organ-directed NGS: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Center

Metastatic Cancer | Local Tumor Invasion

Belgium
OncoMed Pharmaceuticals, Inc.

Terminated

A Study of OMP-313M32 in Subjects With Locally Advanced or Metastatic Solid Tumors

Metastatic Cancer | Locally Advanced Cancer

United States
Verastem, Inc.

Terminated

Phase I Dose Escalation Study of VS-4718 in Subjects With Metastatic Non-Hematologic Malignancies

Metastatic Cancer | Non Hematologic Cancers

United States
Duke Cancer Institute
National Cancer Institute (NCI)

Completed

Immunotherapy in Treating Patients With Resected Liver Metastases From Colon Cancer

Colorectal Cancer | Metastatic Cancer

United States
Grupo Espanol Multidisciplinario del Cancer Digestivo

Recruiting

Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease (LIVERPEARL)

Colorectal Cancer Metastatic | Liver Metastasis Colon Cancer

Spain
Tracon Pharmaceuticals Inc.

Active, not recruiting

Study of TJ004309 in Combination With Atezolizumab (Tecentriq®) in Patients With Advanced or Metastatic Cancer

Solid Tumor | Metastatic Cancer

United States
Eli Lilly and Company

Completed

A Study of Abemaciclib (LY2835219) in Native Chinese Participants With Advanced and/or Metastatic Cancers

Metastatic Cancer | Advanced Cancer

China
Arjun Mittra
National Cancer Institute (NCI)

Recruiting

Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Peritoneum

United States
Maastricht Radiation Oncology
Karolinska Institutet; KU Leuven; Maastricht University Medical Center; Catholic... and other collaborators

Withdrawn

Combination of SABR and L19-IL2 in Patients With Stage IV Lung Cancer (ImmunoSABR) (ImmunoSABR)

NSCLC Stage IV | Limited Metastatic Disease

Netherlands
Oslo University Hospital
Helse Sor-Ost

Active, not recruiting

Oslo Randomized Laparoscopic Versus Open Liver Resection for Colorectal Metastases Study (Oslo-CoMet)

Colorectal Neoplasms | Secondary Malignant Neoplasm of Liver

Norway
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

4D PET/CT in Diagnosing Participants With Lung and Colorectal Cancer With Liver and Lung Metastasis

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Liver | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic...

United States
Peking Union Medical College Hospital

Recruiting

Diagnosis of Metastatic Tumors on 68Ga-FAPI PET-CT and Radioligand Therapy With 177Lu-EB-FAPI

177Lu-EB-FAPI

China
Kristoffer Rohrberg

Recruiting

Thiopurine Enhanced Mutations for PD-1/Ligand-1 Efficacy (TEMPLE)

Metastatic Cancer | Solid Tumor, Adult

Denmark
Thomas Hope
Clovis Oncology, Inc.

Recruiting

Imaging of Solid Tumors Using FAP-2286

Metastatic Cancer | Solid Tumors, Adult

United States
Maastricht University Medical Center
KU Leuven; University College, London; Erasmus Medical Center; Catholic University... and other collaborators

Active, not recruiting

IMMUNOtherapy and Stereotactic ABlative Radiotherapy (IMMUNOSABR) a Phase II Study (IMMUNOSABR2)

NSCLC Stage IV | Metastatic Disease

Netherlands, Belgium, United Kingdom, Germany, France, Italy
Korea University Guro Hospital
Korean Cancer Study Group

Active, not recruiting

Neratinib and Trastuzumab Biosimilar in Patients With HER2 Mutated Advanced Solid Cancers

Metastatic Cancer | HER2 Gene Mutation

Korea, Republic of
Bristol-Myers Squibb
Exelixis

Terminated

A Study of BMS-863233 in Patients With Advanced and/or Metastatic Solid Tumors

Metastatic Cancer | Advanced Solid Cancers

United States, Canada, France
Samsung Medical Center

Active, not recruiting

Patients With Refractory, Metastatic Cancer Harboring KIT Mutation or Amplification to Investigate the Clinical Efficacy and Safety of Imatinib Therapy

Advanced, Refractory Cancer

Korea, Republic of
Haukeland University Hospital
Norwegian Cancer Society; The Norwegian Melanoma Group

Terminated

Bevacizumab vs Dacarbazine in Metastatic Melanoma

Metastatic Malignant Melanoma | Unresectable Malignant Melanoma

Norway
M.D. Anderson Cancer Center
National Cancer Institute (NCI); University of Houston

Recruiting

Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors

Brain Neoplasm | Metastatic Malignant Neoplasm in the Brain | Recurrent Brain Neoplasm

United States
Hospices Civils de Lyon

Recruiting

Tumoral Bone Strength Assessment by Numerical Simulation Using Quantitative CT : the MEKANOS Study (MEKANOS)

Metastatic Breast Cancer | Metastatic NSCLC | Metastases to Bone

France
British Columbia Cancer Agency
BC Cancer Foundation

Recruiting

Personalized Oncogenomics (POG) Program of British Columbia

Advanced Cancers | Metastatic Cancers | Cancers That Cannot be Treated With Curative Intent

Canada
University Hospital, Basel, Switzerland

Not yet recruiting

Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors (ISCA-CHECK)

Advanced Solid Tumor

Switzerland
Lipomedix Pharmaceuticals Inc.

Completed

Intravenously Administered Liposomal PROMITIL in Combination With External Beam Radiotherapy in Cancer Patients

Cancer | Solid Tumor | Metastatic Disease

Israel
Cristal Therapeutics

Completed

A Study of CriPec® Docetaxel Given to Patients With Solid Tumours (NAPOLY)

Cancer | Metastatic Cancer | Solid Tumors

Netherlands, Belgium
The Cleveland Clinic

Unknown

Radiation Therapy in Treating Patients Who Are Undergoing Surgery to Remove a Metastatic Brain Tumor

Metastatic Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies

Metastatic Melanoma | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm

United States
Tata Medical Center

Completed

Dose Escalation Versus Standard in Laryngopharyngeal Cancers (INTELHOPE)

Malignant Neoplasm of Oropharynx Stage III | Malignant Neoplasm of Larynx Stage III | Malignant Neoplasm of Hypopharynx Stage III | Malignant Neoplasm of Oropharynx Stage IVa | Malignant Neoplasm of Oropharynx Stage IVb | Malignant Neoplasm of Larynx Stage IV | Malignant Neoplasm of Hypopharynx... and other conditions

India
Haukeland University Hospital
University of Bergen

Completed

Tissue Characterisation by Endoscopic GI-elastography

Secondary Malignant Neoplasm of Lymph Node | Disorder of Upper Gastrointestinal Tract | Pancreatic Nodule | Secondary and Unspecified Malignant Neoplasm of Retroperitoneal Lymph Nodes

Norway
University of Washington
National Cancer Institute (NCI)

Recruiting

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Soft Tissues | Recurrent Bladder Carcinoma | Recurrent Prostate Carcinoma | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Metastatic Renal Pelvis and Ureter Urothelial Carcinoma | Localized... and other conditions

United States
Parker Institute for Cancer Immunotherapy
Bristol-Myers Squibb; Cancer Research Institute, New York City

Completed

Nivolumab With or Without Ipilimumab in Advanced Metastatic Cancer

Advanced Metastatic Cancer | Advanced Prostate Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Cutaneous Melanoma | Recurrent Malignant Female Reproductive System Neoplasm | Refractory Malignant Female Reproductive System Neoplasm | Recurrent Lip and Oral Cavity Carcinoma | Recurrent Malignant Endocrine... and other conditions

United States
Proviva Therapeutics, Inc.

Not yet recruiting

A First-in-human (FIH), Multicenter, Open-Label, Phase I Study of PTX-912 in Patients With Locally Advanced/Metastatic Solid Tumors

Solid Tumor | Metastatic Cancer | Advanced Cancer
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Monalizumab and MEDI5752 in Patients With MSI and/or dMMR Metastatic Cancer (MONAMI)

MSI | dMMR Colorectal Cancer

France
Qurient Co., Ltd.

Recruiting

Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor in Patients With Advanced Solid Tumor

Solid Tumor | Metastatic Cancer | Advanced Cancer

United States
Roshni Dasgupta

Recruiting

The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

Solid Malignancies | Metastatic Disease | Primary Tumor

United States
Hospital Universitario Araba
Hospital Donostia; Hospital de Basurto; Complejo Hospitalario de Navarra; Hospital...

Recruiting

Autoantibodies in Treatment With Immune Checkpoint Inhibitors (AUTENTIC) (AUTENTIC)

Cancer | Metastatic Cancer | Solid Organ Cancer

Spain
National Cancer Institute (NCI)

Active, not recruiting

Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)

Metastatic Cancer | Solid Tumors

United States
I-Mab Biopharma Co. Ltd.

Completed

Study of TJ210001 Administered in Subjects With Relapsed or Refractory Advanced Solid Tumors

Solid Tumor | Metastatic Cancer | Advanced Cancer

United States
University of Washington
National Cancer Institute (NCI)

Completed

18F-FLT PET/CT in Measuring Cell Proliferation in Patients With Brain Tumors

Metastatic Malignant Neoplasm in the Brain | Recurrent Brain Neoplasm | Primary Brain Neoplasm

United States
Case Comprehensive Cancer Center

Not yet recruiting

Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE) (TRANSCAPE)

Pseudomyxoma Peritonei | Secondary Malignant Neoplasm of Peritoneum | Secondary Malignant Neoplasm of Retroperitoneum

United States
Stanford University

Completed

CT Perfusion Imaging in Predicting Treatment Response in Patients With Non-small Cell Lung Cancer or Lung Metastases Treated With Stereotactic Ablative Radiation Therapy

Stage IV Lung Cancer | Metastatic Malignant Neoplasm in the Lung | Non-Small Cell Lung Carcinoma | Malignant Lung Neoplasm

United States
OHSU Knight Cancer Institute
Novartis Pharmaceuticals; Oregon Health and Science University

Completed

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Locally Advanced Leiomyosarcoma | Unresectable Leiomyosarcoma | Myxofibrosarcoma | Metastatic Malignant Peripheral Nerve Sheath Tumor | Metastatic Synovial Sarcoma | Metastatic Undifferentiated Pleomorphic Sarcoma | Unresectable... and other conditions

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

NaF PET/MRI Evaluation for Bone Metastases in Breast Cancer

Malignant Neoplasm of Breast TNM Staging Distant Metastasis (M) | Untreated Bone Metastases

United States
Assistance Publique Hopitaux De Marseille

Unknown

Precarious Elderly Patient Supported For Cancer Impact on Quality Of Life of a Domotic And Remote Assistance Approach for Elderly Patients Supported For Locally Advanced or Metastatic Cancer, Socially Isolated (PREDOMOS)

Elderly | Locally Advanced or Metastatic Cancer

France
European Organisation for Research and Treatment...

Withdrawn

Nintedanib Plus mFOLFOX6 for Previously Untreated Metastatic Esophagogastric Adenocarcinoma (MEGAN) (MEGAN)

Metastatic Disease | Esophagogastric Adenocarcinoma | No Previous Chemotherapy for Metastatic Esophagogastric Cancer
Orion Biotechnology Polska Sp. z o.o.

Not yet recruiting

Study of OB-002 in Patients With Refractory Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Cancer | Metastatic Breast Cancer | Metastatic Urothelial Carcinoma | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer
Dr. Ronnie Shapira

Not yet recruiting

Overcoming Primary Resistance to Immunotherapy in Metastatic Melanoma (MK3475-C01)

Metastatic Melanoma | Malignant Melanoma | Immunotherapy | Malignant Melanoma Stage IV | BRAF V600E
European Institute of Oncology

Recruiting

Evaluation of a Music and Interaction Intervention on Patient Distress During Whole Body Magnetic Resonance

Neoplasm Malignant

Italy

Clinical Trials on Metastatic Malignant Neoplasm

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