Clinical Trials on Metastatic Colo-rectal Cancer in United Kingdom

Total 6859 results

Chandrikha Chandrasekharan
AstraZeneca; Biocompatibles UK Ltd

Suspended

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer (iRE-C)

Metastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon Cancer

United States
University of Manchester
Manchester University NHS Foundation Trust; The Christie NHS Foundation Trust; Perspect... and other collaborators

Unknown

Colorectal Liver Metastases: Novel Assessment Tools for Technical Resectability (CoNoR)

Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Cancer Metastatic

United Kingdom
Amal Therapeutics
Boehringer Ingelheim

Active, not recruiting

Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01)

Metastatic Colorectal Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | MSS

United States, Belgium, Switzerland, Germany
University of California, San Francisco
Bristol-Myers Squibb; Pfizer

Terminated

Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer

Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal... and other conditions

United States
University of Utah

Not yet recruiting

Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Metastatic Colorectal Cancer (FACE)

Metastatic Colon Cancer | Metastatic Rectum Cancer

United States
London North West Healthcare NHS Trust

Active, not recruiting

Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES) (BiCyCLE-NMES)

Colorectal Cancer | Rectal Cancer | Sarcopenia | Advanced Cancer | Colon Cancer | Colo-rectal Cancer | Sarcopenic Obesity | Recurrent Rectal Cancer

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Advanced Colon Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer... and other conditions

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb; Syntrix Biosystems, Inc.

Recruiting

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
AEterna Zentaris

Completed

Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients

Colon Cancer

United States
WntResearch AB

Completed

Dose Escalating Study of Foxy-5 in Breast-, Colon- or Prostate Cancer Patients

Metastatic Breast Cancer | Metastatic Prostate Cancer | Metastatic Colon Cancer

Denmark, United Kingdom
QIAGEN Gaithersburg, Inc
Amgen

Recruiting

Therascreen® KRAS RGQ PCR Kit

Colo-rectal Cancer

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colon Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Metastatic Microsatellite Stable Colorectal Carcinoma

United States
Mayo Clinic

Completed

A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic... and other conditions

United States
Dana-Farber Cancer Institute
American Cancer Society, Inc.

Not yet recruiting

Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

Metastatic Colorectal Cancer | Colorectal Cancer | Metastatic Colon Cancer

United States
University of Ulster
Belfast Health and Social Care Trust

Unknown

EXercise And Colo-Rectal Cancer Trial (EXACT)

Colo-rectal Cancer

United Kingdom
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Tucatinib Combined With Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colon Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer

Recurrent Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 and other conditions

United States
University of Leeds
National Cancer Institute (NCI); Massachusetts General Hospital; Massachusetts... and other collaborators

Recruiting

Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases

Colon Cancer Liver Metastasis

United Kingdom
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Terminated

Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Colon Cancer AJCC... and other conditions

United States
London North West Healthcare NHS Trust

Completed

Detection in Tandem Endocuff Cap Trial (DETECT)

Colonic Neoplasms | Colo-rectal Cancer | Colon Adenoma | Adenomas Serrated

United Kingdom
Asana BioSciences

Completed

A Study of ASN007 in Patients With Advanced Solid Tumors

Cancer | Neoplasm Metastasis | Pancreatic Cancer | Metastatic Cancer | Metastatic Lung Cancer | Pancreas Adenocarcinoma | Metastatic Melanoma | Colon Cancer | Colonic Neoplasms | Pancreas Cancer | Non Small Cell Lung Cancer Metastatic | Neoplasm | Pancreas Neoplasm | Metastatic Pancreatic Cancer | Metastatic Colon Cancer and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer

Pancreatic Adenocarcinoma | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Pancreatic Ductal Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Rectal Adenocarcinoma | Stage IIIA Colon Cancer | Stage IIIB Colon... and other conditions

United States
Immodulon Therapeutics Ltd

Terminated

Study of IMM 101 in Combination With Standard of Care in Patients With Metastatic or Unresectable Cancer (MODULATE)

Metastatic Cancer

France, United Kingdom
Fundación de Investigación Biomédica - Hospital...
Marcello Di Martino

Completed

Chemotherapy for Resectable Colorectal Liver Metastases

Metastatic Colorectal Cancer | Metastatic Liver Cancer

Spain, United Kingdom, France
National Cancer Institute (NCI)

Terminated

Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer

Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage... and other conditions

United States
UConn Health
California Walnut Commission; American Institute for Cancer Research; The Jackson...

Completed

Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption

Colon Cancer | Colo-rectal Cancer | Diet Habit

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IV Colon Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Unresectable Colon Adenocarcinoma | Unresectable Rectal Adenocarcinoma

United States, Puerto Rico
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Colorectal Carcinoma | Stage III Colon Cancer AJCC v7 | Stage III Rectal Cancer AJCC v7 | Stage IIIA Colon Cancer AJCC v7 | Stage IIIA Rectal Cancer AJCC v7 | Stage IIIB Colon... and other conditions

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
Stanford University
Caring for Carcinoid Foundation; GI Cancer Research Gift Fund

Withdrawn

Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers

Gastrointestinal Neoplasms | Pancreatic Cancer | Anal Cancer | Colon/Rectal Cancer | Hepatobiliary Cancers | Gastric (Stomach) Cancer | Gynecologic Cancers | Gastro-Esophageal(GE) Junction Cancer | Gynecologic Cancers Cervical Cancer | Gastrointenstinal Stromal Tumor (GIST) | Colon/Rectal Cancer Colon Cancer and other conditions

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers

Metastatic Cancers

United States
Perspectum

Active, not recruiting

Precision Medicine for Liver Tumours With Quantitative Magnetic Resonance Imaging and Whole Genome Sequencing (Precision1)

Liver Cancer | Liver Metastasis Colon Cancer

United Kingdom
Glasgow Royal Infirmary

Recruiting

Advanced Pelvic Surgical Oncology Database - Prospective Observational Study

Gynecologic Cancer | Rectal Cancer | Pelvic Cancer | Colon Cancer

United Kingdom
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Programs to Support You During Chemotherapy (Pro-You) (Pro-You)

Fatigue | Depressive Symptoms | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Psychosocial Effects of Cancer and Its Treatment | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon... and other conditions

United States
The Christie NHS Foundation Trust

Not yet recruiting

Irinotecan Drug-eluting Bead Liver Embolisation Registry (DLivERDEBIRI)

Colorectal Cancer Metastatic | Liver Metastases

United Kingdom
Siemens Molecular Imaging

Completed

Efficacy Study of [F-18]RGD-K5 Positron Emission Tomography (PET) as a Tool to Monitor Response to an Anti-angiogenic Drug (K5-101)

Non-squamous Non-small Cell Lung Cancer | Metastatic Breast Cancer | Metastatic Colon/Rectum Cancer

United States
Freenome Holdings Inc.

Completed

AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test

Adenoma | Polyps | Cancer, Rectum | Polyp of Colon | Colo-rectal Cancer | Adenoma Colon | Neoplasms,Colorectal | Cancer Colon

United States, Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Liver Metastases | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Stanford University

Completed

Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm

Polyp of Colon | Colo-rectal Cancer | Adenomatous Polyp of Colon

United States
M.D. Anderson Cancer Center

Recruiting

Combination Therapy for Cancer Related Fatigue in Patients With Metastatic Cancers

Fatigue | Metastatic Cancers

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Active, not recruiting

TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Colon Cancer AJCC v8 | Stage IV Colon Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

Colorectal Cancer | Colon Cancer | Liver Metastasis Colon Cancer | Adenocarcinoma of the Rectum | Colon Cancer Liver Metastasis | Adenocarcinoma of the Colon

United States
Generic Devices Consulting, Inc.
Biocompatibles UK Ltd

Terminated

Chemoembolization, Irinotecan Bead, Second Line Chemotherapy Treatment of Unresectable Metastatic Colorectal Cancer (PARAGON)

Unresectable Metastatic Colo-rectal Cancer

United States
Advaxis, Inc.

Terminated

A Study of ADXS-NEO Expressing Personalized Tumor Antigens (NEO)

Metastatic Melanoma | Urothelial Carcinoma | Metastatic Non-Small Cell Lung Cancer | Head and Neck Cancer Metastatic | Colon Cancer Metastatic

United States
Stanford University

Terminated

Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors

Head and Neck Cancer | Colorectal Neoplasms | Lung Cancer | Colon Cancer | Colonic Neoplasms | Head and Neck Cancers | Anal, Colon, and Rectal Cancers | Colon/Rectal Cancer | Colon/Rectal Cancer Colon Cancer | Colon/Rectal Cancer Rectal Cancer | Colon/Rectal Cancer Anal Cancer | Head and Neck Cancers Lip | Head... and other conditions

United States
Royal Marsden NHS Foundation Trust

Active, not recruiting

iSCORE: Immunotherapy Sequencing in COlon and REctal Cancer

Metastatic Colorectal Cancer

United Kingdom
University of Manchester
Manchester University NHS Foundation Trust; National Institute for Health Research... and other collaborators

Unknown

The CLiFF Study: Change in Liver Function and Fat in Pre-operative Chemotherapy for Colorectal Liver Metastases (CLiFF)

Obesity | Colorectal Cancer | Chemotherapy Effect | Liver Metastasis Colon Cancer

United Kingdom
Case Comprehensive Cancer Center

Completed

PET-MRI in Diagnosing Patients With Colon or Rectal Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer and other conditions

United States
European Organisation for Research and Treatment...
Japan Clinical Oncology Group; European Society of Surgical Oncology

Completed

Diffusion-Weighted MRI for Liver Metastasis (DREAM)

Colorectal Cancer | Colon Cancer Liver Metastasis | Malignant Neoplasm of Rectum Metastatic to Liver

France, Japan, Belgium, United States, Austria
City of Hope Medical Center

Completed

Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States

Clinical Trials on Metastatic Colo-rectal Cancer in United Kingdom

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