Clinical Trials on Metastatic Cancer

Total 54992 results

Boston Scientific Corporation

Withdrawn

Study Comparing Radio Frequency Ablation Plus Chemotherapy and Chemotherapy Alone in Patients With Secondary Liver Metastases (Prometheus)

Liver Neoplasm | Metastatic Liver Cancer | Secondary Liver Cancer

United States
Genentech, Inc.

Completed

A Study of the Safety, Tolerability, and Effects of Cobimetinib and GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors

Non-Small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma

United States
Washington University School of Medicine
Varian Medical Systems

Completed

Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device

Intracranial Metastatic Disease From Any Solid Malignancy

United States
Eli Lilly and Company

Completed

A Study of LY2334737 in Participants With Cancer That is Advanced and/or Has Spread

Solid Tumor | Malignant Solid Tumor | Metastatic Tumor

Germany, United States, France
Jiangsu Simcere Pharmaceutical Co., Ltd.

Unknown

Study of Metatinib Tromethamine Tablet

Advanced or Metastatic Gastric Cancer | Advanced or Metastatic CRC | Advanced or Metastatic Liver Cancer | Advanced or Metastatic Non Squamous NSCLC

China
National Cancer Institute (NCI)

Withdrawn

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated or Viral Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab

Metastatic HPV-16 Positive Squamous Cell Anal Cancer

United States
Ankara University

Recruiting

Metastatic Pathologic Fractures, Short Term Results

Metastatic Cancer | Bone Metastases | Pathologic Fracture

Turkey
University of Arkansas

Withdrawn

The P10s-PADRE Basket Trial: Vaccination of Metastatic Cancer Patients

Neoplasms by Site | Metastatic Cancer
Weprom
Neptune

Active, not recruiting

Prophylaxis of Magnesium-rich Mineral Water to Prevent Hypomagnesemia Induced by an Anti-EGFR (OPTIMAG) (OPTIMAG)

Metastatic Colorectal Cancer | Metastatic Head and Neck Cancer

France
Nantes University Hospital

Completed

Medico-economic Evaluation Comparing the Impact of the New Fixed-dose Nivolumab Regimen With the Old mg/kg Regimen in the Management of Patients With Metastatic Cancer (IMEPOCA)

Metastatic Cancer
Valley Health System

Recruiting

Determine Safety & Recommended Phase 2 Dosing of Zeaxanthin Alone or in Combination w/Pembrolizumab in Patients With Metastatic Cancer

Metastatic Solid Tumor | Cancer Metastatic

United States
Memorial Sloan Kettering Cancer Center

Withdrawn

Detection of Acid Sphingomyelinase/Ceramide Pathway Activation in Radiotherapy Patients Using Intravoxel Incoherent Motion (IVIM) Diffusion-weighted Magnetic Resonance Imaging and Serum Biomarkers

Metastatic Disease to Bone | Metastatic Disease to Soft Tissue

United States
University of Regensburg

Completed

CE-IOUS Impact on Surgical Strategy of Liver Tumours and Liver Metastases

Liver Neoplasms | Surgery | Colorectal Cancer Metastatic | Ultrasound | Metastases | Liver/Hepatobiliary Cancer

Germany
M.D. Anderson Cancer Center

Recruiting

A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)

OligoProgressive Metastatic Disease

United States
Tokyo Medical and Dental University

Recruiting

Metastasis-directed Therapy for Oligometastases of Breast Cancer (OLIGAMI)

Breast Cancer | Metastatic Breast Cancer | Oligometastasis

Japan
David Peereboom, MD
National Cancer Institute (NCI)

Completed

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer

Breast Cancer | Metastatic Cancer

United States
University of Alabama at Birmingham
University of South Alabama

Recruiting

Lay Coach-Led Early Palliative Care for Underserved Advanced Cancer Caregivers: The Project ENABLE Cornerstone RCT

Cancer Metastatic | Family Members

United States
Monika Joshi, MD
Pfizer; Eisai Inc.; Big Ten Cancer Research Consortium

Terminated

A Study Combining Eribulin Mesylate With Avelumab in Cisplatin Ineligible Metastatic Urothelial Cell Cancer Patients

Metastatic Urothelial Cell Cancer

United States
Gustave Roussy, Cancer Campus, Grand Paris

Active, not recruiting

A Prospective Trial to Study the Evolution of Clonal Architecture of Tumors From Patients Treated With Molecular Targeted Agents (MATCH-R)

Metastatic Oncogen-driven Cancer

France
Istituto Clinico Humanitas

Active, not recruiting

High Dose SBRT for Abdominal-Pelvic Lymph Nodal Lesions in Oligometastatic Patients

Lymph Node Cancer Metastatic

Italy
University of Alabama at Birmingham
National Institute of Nursing Research (NINR)

Completed

An Upstream Palliative Care Intervention for Rural and African-American Advanced Cancer Family Caregivers

Family Members | Cancer, Metastatic

United States
WntResearch AB

Completed

Dose Escalating Study of Foxy-5 in Breast-, Colon- or Prostate Cancer Patients

Metastatic Breast Cancer | Metastatic Prostate Cancer | Metastatic Colon Cancer

Denmark, United Kingdom
Swiss Group for Clinical Cancer Research

Active, not recruiting

Prevention of Symptomatic Skeletal Events With Denosumab Administered Every 4 Weeks Versus Every 12 Weeks

Metastatic Breast Cancer | Bone Metastases | Metastatic Prostate Cancer

Switzerland, Germany, Austria
Shanghai Miracogen Inc.

Recruiting

A Study of MRG002 Versus Investigator's Choice of Chemotherapy in the Treatment of Patients With HER2-positive Unresectable Advanced or Metastatic Urothelial Cancer

Advanced or Metastatic Urothelium Cancer

China
National Cancer Institute (NCI)

Completed

Phase II Study of Metastatic Cancer That Overexpresses P53 Using Lymphodepleting Conditioning Followed by Infusion of Anti-P53 TCR-Gene Engineered Lymphocytes

Anti-p53 TCR-Gene

United States
Region Skane

Recruiting

On-treatment Biomarkers in Metastatic Colorectal Cancer for Life (On-CALL)

Metastatic Colorectal Cancer | Lung Metastases | Chemotherapy Effect | Peritoneal Metastases | Liver Metastasis Colon Cancer

Sweden
University of Michigan Rogel Cancer Center
Memorial Sloan Kettering Cancer Center; University of California, San Francisco

Active, not recruiting

Immunotherapy in Patients With Metastatic Cancers and CDK12 Mutations (IMPACT)

Solid Tumor | Metastatic Cancer | Metastatic Castration Resistant Prostate Cancer

United States
Mirati Therapeutics Inc.
Novartis

Active, not recruiting

Adagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2)

Metastatic Cancer | Advanced Cancer | Malignant Neoplastic Disease

United States
MacroGenics

Completed

Margetuximab Plus Chemotherapy vs Trastuzumab Plus Chemotherapy in the Treatment of HER2+ Metastatic Breast Cancer (SOPHIA)

HER-2 Positive Breast Cancer | Metastatic Neoplasm

United States, Spain, Italy, Canada, Israel, Belgium, Germany, Czechia, Austria, Korea, Republic of, Denmark, United Kingdom, Portugal, France, Poland, Netherlands, Finland, Puerto Rico
Symphogen A/S

Active, not recruiting

Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies

Solid Tumor | Metastatic Cancer

United States, Canada
Hotel Dieu de France Hospital

Completed

Dexmedetomidine Addition to Morphine in Patients With Metastatic Cancer

Metastatic Cancer | Refractory Pain
Gene Solutions

Recruiting

Analysis of PD-L1, TMB, MSI and ctDNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.

Breast Cancer | Gastric Cancer | Colorectal Cancer | Non Small Cell Lung Cancer | Advanced Cancer | Liver Cancer | Immune Checkpoint Inhibitor

Vietnam
Enzon Pharmaceuticals, Inc.

Terminated

Efficacy of Pegamotecan (PEG-Camptothecin) in Localized or Metastatic Cancer of the Stomach or Gastroesophageal Junction

Cancer of Stomach | Gastroesophageal Cancer
Centre Oscar Lambret

Completed

Study of Stress and Life Quality of Patients Participating in Clinical Trials Versus Patients Non Participating (IPSY)

Metastatic Neoplasm | Recurrent Hematologic Cancer

France
Centre Francois Baclesse
Roche Pharma AG; Hospira, now a wholly owned subsidiary of Pfizer; Vifor Pharma

Terminated

Randomized Study Evaluating Agents Stimulants Erythropoiesis (ASE) Associated With Ferric Carboxymaltose (Ferinject ®) in Concomitant or Sequential Patients Treated for Cancer and With Anemia Associated With Functional Iron Deficiency

Solid Cancer Metastatic Disease | Lymphoid Disease

France
I-Mab Biopharma Co. Ltd.

Recruiting

Study of TJ033721 in Subjects With Advanced or Metastatic Solid Tumors

Gastric Cancer | Solid Tumor | Metastatic Cancer | Advanced Cancer | Esophageal Adenocarcinoma | Gastroesophageal Junction Carcinoma

United States, China
Berg, LLC

Completed

BP31510 (Ubidecarenone,USP) Nanosuspension for Intravenous Injection to Patients With Solid Tumors

Cancer | Solid Tumor | Metastatic Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Docetaxel With or Without Imatinib Mesylate in Treating Patients With Androgen-Independent Prostate Cancer and Bone Metastases

Prostate Cancer | Metastatic Cancer

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic Cancer | Pancreatic Cancer Metastatic | Pancreatic Cancer Stage IV | Metastatic Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Pancreatic Carcinoma | Metastatic Pancreatic Cancer | Pancreatic Cancer Non-resectable | Metastatic Pancreatic Ductal Adenocarcinoma | Pancreatic Carcinoma... and other conditions

United States
QSAM Therapeutics, Inc.

Recruiting

A Dose Finding Study to Treat Bone Tumor(s)

Bone Cancer | Solid Tumor | Bone Tumor | Metastatic Cancer to the Bone | Metastatic Tumor to the Bone

United States
Cue Biopharma

Recruiting

A Phase 1 in Patients With HLA-A*0201+ and WT1+ Recurrent/Metastatic Cancers

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer

United States
Tesaro, Inc.

Active, not recruiting

Study of Niraparib, TSR-022, Bevacizumab, and Platinum-Based Doublet Chemotherapy in Combination With TSR-042

Neoplasms | Solid Tumor | Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | Non Small Cell Lung Cancer Stage IIIB | Non Small Cell Lung Cancer Metastatic

United States
SCRI Development Innovations, LLC
Sanofi; GlaxoSmithKline; Novartis

Terminated

Cabazitaxel Plus Lapatinib as Therapy for HER2-Positive Metastatic Breast Cancer Patients With Intracranial Metastases

Metastatic Breast Cancer With Intracranial Metastases

United States
CanWell Pharma Inc.

Recruiting

Intratumoral CAN1012(Selective TLR7 Agonist) in Subjects With Solid Tumors

Solid Tumor | Cancer Metastatic

United States
Kiromic, Inc.

Withdrawn

Consolidation Therapy in Patients With Metastatic Solid Malignancies

Cancer | Metastatic Solid Malignancies
Gilead Sciences

Recruiting

Study of Sacituzumab Govitecan (SG) in Japanese Participants With Advanced Solid Tumors (ASCENT-J02)

Advanced Solid Tumor | Metastatic Urothelial Cancer | Metastatic Triple-Negative Breast Cancer | HR+/HER2- Metastatic Breast Cancer

Japan
Suzhou Transcenta Therapeutics Co., Ltd.

Recruiting

A First-in-Human, Phase 1 Study of TST003 in Subjects With Solid Tumors

Colorectal Adenocarcinoma | Locally Advanced Solid Tumor | Metastatic Tumor

United States
Case Comprehensive Cancer Center

Recruiting

Spine Radiosurgery for Symptomatic Metastatic Neoplasms

Metastatic Neoplasm | Metastatic Neoplasm to the Spine

United States
Nektar Therapeutics

Completed

A Study in Cancer Patients to Evaluate the Effect of a Single Dose of NKTR-102 (Etirinotecan Pegol) on the QTc Interval and to Assess Pharmacokinetics and Safety

Advanced Cancer | Metastatic Solid Tumors

United States
Centre hospitalier de l'Université de Montréal...

Recruiting

Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic Cancer (SUPPRESS)

Head and Neck Cancer | Oligoprogressive | Metastatic Cancer

Canada

Clinical Trials on Metastatic Cancer

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