Clinical Trials on Metastatic Disease to Bone

Total 34228 results

Memorial Sloan Kettering Cancer Center

Withdrawn

Detection of Acid Sphingomyelinase/Ceramide Pathway Activation in Radiotherapy Patients Using Intravoxel Incoherent Motion (IVIM) Diffusion-weighted Magnetic Resonance Imaging and Serum Biomarkers

Metastatic Disease to Bone | Metastatic Disease to Soft Tissue

United States
Stony Brook University
The University of Texas Health Science Center at San Antonio

Recruiting

Definitive Radiation for High-Risk Spine Metastases

Metastatic Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastasis | Spine Metastases | Metastatic Tumor | Metastatic Tumor of Bone | Metastatic Tumor to the Spine

United States
QSAM Therapeutics, Inc.

Recruiting

A Dose Finding Study to Treat Bone Tumor(s)

Bone Cancer | Solid Tumor | Bone Tumor | Metastatic Cancer to the Bone | Metastatic Tumor to the Bone

United States
Hospices Civils de Lyon

Recruiting

Tumoral Bone Strength Assessment by Numerical Simulation Using Quantitative CT : the MEKANOS Study (MEKANOS)

Metastatic Breast Cancer | Metastatic NSCLC | Metastases to Bone

France
Rigshospitalet, Denmark

Recruiting

Fully Constrained Acetabular Liner vs. Dual Mobility Hip Joint in the Surgical Treatment of Metastatic Bone Disease of the Hip

Metastatic Cancer to the Hip

Denmark
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Dual Energy Computed Tomography (CT) in Finding Bone Metastases in Patients With Cancer

Malignant Neoplasm | Metastatic Malignant Neoplasm to the Bone

United States
Ottawa Hospital Research Institute

Withdrawn

Project to Assess Feasibility of a Rapid Access Metastatic Bone Disease Program (RAMP)

Metastases to Bone
MedtronicNeuro

Completed

OsteoCool Tumor Ablation Post-Market Study (OPuS One)

Metastasis Spine | Metastasis to Bone

United States, Luxembourg, Germany, France, Canada
Case Comprehensive Cancer Center

Recruiting

Spine Radiosurgery for Symptomatic Metastatic Neoplasms

Metastatic Neoplasm | Metastatic Neoplasm to the Spine

United States
RefleXion Medical

Completed

Performance and Safety of Biology-Guided Radiotherapy Using the RefleXion Medical Radiotherapy System (BIOGUIDE-X) (BIOGUIDE-X)

Cancer | Tumor, Solid | Cancer, Lung | Metastasis to Bone | Metastasis to Lung | Cancer, Bone

United States
Institut Bergonié
French Sarcoma Group

Active, not recruiting

Patterns of Care and Outcomes in Patients With Metastatic Bone Tumors (METABONE) (METABONE)

Metastatic Bone Tumor

France
Dana Mathews

Withdrawn

68Ga PSMA-11 PET/CT in Recurrent Prostate Cancer

Prostate Cancer | Prostate Cancer Metastatic | Prostate Cancer Metastatic to Bone

United States
Leiden University Medical Center

Unknown

Post-operative RadioTherapy for Patients With Metastases of the Long Bones (PORT)

Metastasis to Bone

Netherlands
Spanish Breast Cancer Research Group
Novartis Pharmaceuticals

Completed

Study of the Utility of the BOMET-QOL Questionnaire Patients With Breast Cancer and Bone Metastasis (MAbomet)

Breast Carcinoma Metastatic to the Bone

Spain
Piotr Biega

Completed

Tranexamic Acid After Pathological Fracture Treated With Modular Arthroplasty

Metastases to Bone

Poland
University of Virginia

Completed

Rapid Radiation Therapy for Painful Osseous Metastatic Disease

Bone Metastases

United States
Cancer Research Antwerp

Completed

A Trial to Improve Quality of Life With Stereotactic Body Radiotherapy for Patients With Painful Bone Metastases (ROBOMET)

Neoplasm Metastasis | Radiotherapy | Metastasis to Bone

Belgium
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Telemonitoring After Surgery to Preserve Limb Function in Optimizing Mobility in Cancer Survivors With Skeletal Metastases

Bone Metastases | Cancer Survivor | Metastatic Malignant Neoplasm in the Bone

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Completed

Cytoreductive Prostatectomy in Treating Patients With Newly Diagnosed, Metastatic Prostate Cancer

Metastatic Prostate Carcinoma | Metastatic Prostatic Adenocarcinoma | Prostate Carcinoma Metastatic to the Bone

United States
University Health Network, Toronto

Recruiting

Femoral Bone Metastases

Cancer | Metastatic Malignant Neoplasm to Femur | Risk of Fracture

Canada
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Withdrawn

Role of Hyaluronic Acid in Causing Cancer Stem Cell Growth in the Bones of Patients With Breast Cancer

Stage IV Breast Cancer | Breast Carcinoma Metastatic to the Bone

United States
Smith & Nephew, Inc.

Completed

PMCF Study on PEEK Suture Anchors for Shoulder Indications

Soft Tissue to Bone Fixation

United States
Smith & Nephew, Inc.

Completed

PMCF Study on PEEK Suture Anchors for Hip Indications

Soft Tissue to Bone Fixation

United States
St. Justine's Hospital

Withdrawn

Denosumab for Prevention of Bone Complications After Bone Marrow Transplantation in Children

Disorder Related to Bone Marrow Transplantation

Canada
University of Cincinnati

Recruiting

Palliative UNConventional Hypofractionation Trial for Metastatic Bone Disease (1-2 PUNCH)

Metastatic Bone Tumor

United States
Maastricht University
Aalborg University Hospital; Centre Hospitalier Universitaire de Liege; University... and other collaborators

Completed

Automated Detection of Metastatic Bone Disease on Bone Scintigraphy Scans

Metastatic Bone Tumor

Netherlands
Amgen

Withdrawn

Evaluate Time Associated With the Preparation & Administration of Denosumab/Pamidronate in Patients With Solid Tumors and Metastatic Bone Disease

Solid Tumor | Metastatic Bone Disease
Ankara University

Recruiting

Metastatic Pathologic Fractures, Short Term Results

Metastatic Cancer | Bone Metastases | Pathologic Fracture

Turkey
Bayer

Completed

Radium-223 Dichloride Long-term Follow-up Program

Neoplasm Metastasis / Bone and Bones

Belgium, Spain, Taiwan, United States, Japan, Russian Federation, Canada, Finland, Korea, Republic of, Singapore, Australia, Germany, Israel, United Kingdom, Italy, France, Poland, Brazil, Czechia, Norway, Sweden, Hong Kong
Novartis Pharmaceuticals

Completed

Effect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer Patients (MACS1295)

First or Second Line HER2-negative Breast Cancer | Metastatic Disease Without Bone Metastasis

United States
Amsterdam UMC, location VUmc

Active, not recruiting

Rhenium-188-HEDP vs. Radium-223-chloride in Patients With Advanced Prostate Cancer Refractory to Hormonal Therapy (RaRe)

Prostate Cancer Metastatic to Bone

Netherlands
Herlev Hospital

Unknown

Diagnostic Imaging of Bone Metastases in Prostate Cancer Patients (DIMAB)

Prostate Cancer Metastatic to Bone

Denmark
UNC Lineberger Comprehensive Cancer Center

Completed

Safety, Efficacy, and Dosing of Stereotactic Radiosurgery for Hepato-cellular Carc/Colo-rectal Liver Metastases

Liver Neoplasms | Colonic Neoplasms | Metastatic Cancer to Liver

United States
UNICANCER
National Cancer Institute, France

Recruiting

Standard Treatment +/- SBRT in Solid Tumors Patients With Between 1 and 5 Bone-only Metastases (STEREO-OS)

Metastatic Lung Cancer | Metastatic Breast Cancer | Bone Metastases | Metastatic Prostate Cancer

France
Chuangzhen Chen

Recruiting

Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Solid Tumors (ILDRV1)

Radiotherapy | Immune Checkpoint Blockade | Metastatic Extracranial Malignant Solid Neoplasm | Resistance to Immunotherapy

China
Henry Ford Health System

Completed

Effect of Epidural Steroid Injection on Bone Mineral Density in Postmenopausal Women

To Assess the Changes in Markers of Bone Turnover Over a Six Month Period After Epidural Steroid Inject | To Assess the Changes in Bone Mineral Density

United States
Pfizer
Astellas Pharma Inc; Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Completed

A Positron Emission Tomography/Computed Tomography (PET/CT) Bone Imaging Study in Patients Receiving Enzalutamide for Castration-Resistant Prostate Cancer (CRPC)

Castration Resistant Prostate Cancer | Prostate Carcinoma Metastatic to the Bone

United States
Carolina Research Professionals, LLC
Astellas Pharma Inc

Completed

Open Label Phase Two Study of Enzalutamide With Concurrent Administration of Radium Ra 223 Dichloride in Castration-Resistant (Hormone-Refractory) Prostate Cancer Subjects With Symptomatic Bone Metastasis

Prostate Carcinoma Metastatic to the Bone

United States
University of Siena

Unknown

Randomized Controlled Trial of Full-Arch Rehabilitation

Bone-to-implant Contact | Success Rate | Survival Rate

Italy
Peking University Third Hospital

Completed

Comparison of Techniques Between Concave Distraction and Convex Resection in the Treatment of Congenital Cervical Scoliosis

Congenital Scoliosis Due to Bony Malformation | Cervical Scoliosis

China
Heidelberg University

Completed

Isometric Muscle Training in Patients With Spinal Bony Metastases Under Radiation Therapy (DISPO)

Vertebral Bony Metastases

Germany
Massachusetts General Hospital
Bayer

Completed

A Biomarker Study of Standard-of-care Radium-223 Chloride for Metastatic Castration-resistant Prostate Cancer

Prostate Cancer | Castration-resistant Prostate Cancer | Castration-resistant Prostate Cancer Metastatic to Bone

United States
Istituto Clinico Humanitas

Active, not recruiting

Study on SBRT for Inoperable Lung and Liver Oligometastases From Breast Cancer

Breast Cancer | Metastasis to Liver | Metastasis to Lung

Italy
M.D. Anderson Cancer Center

Terminated

Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System

Leukemia | Metastatic Malignant Neoplasm to the Leptomeninges | Lymphoid Malignancies

United States
National Taiwan University Hospital

Recruiting

ERAS Anesthetic Care for Metastatic Spine Cancer Resection

Metastatic Bone Tumor

Taiwan
University of Michigan
M.D. Anderson Cancer Center; Memorial Sloan Kettering Cancer Center; National... and other collaborators

Completed

Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic Cancer

Bone Diseases | Osteonecrosis | Metastases | Bisphosphonate-Associated Osteonecrosis of the Jaw

United States
Rigshospitalet, Denmark
Ethicon, Inc.

Completed

Occlusive Skin Closure May Reduce Wound Drainage After Tumor Hip Arthroplasty

Metastatic Bone Disease of the Proximal Femur

Denmark
University of Michigan Rogel Cancer Center

Completed

Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic Cancer: Concordance Study

Breast Cancer

United States
University of Utah
Bayer

Completed

Radium-223 and Radiotherapy in Hormone-Naïve Men With Oligometastatic Prostate Cancer to Bone (RROPE)

Prostate Cancer Metastatic to Bone

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Metastatic Malignant Neoplasm in the Bone | Peripheral Primitive Neuroectodermal Tumor of Soft Tissues | Metastatic Malignant Neoplasm in the Lung | Metastatic Ewing Sarcoma | Metastatic Malignant Neoplasm in the Bone Marrow | Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone

United States, Canada, Puerto Rico

Clinical Trials on Metastatic Disease to Bone

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