Clinical Trials on Metastatic Malignant Neoplasm in the Liver

Total 1995 results

European Organisation for Research and Treatment...
European Society of Surgical Oncology

Completed

A Prospective Colorectal Liver Metastasis Database With an Integrated Quality Assurance Program (CLIMB)

Colorectal Carcinoma | Liver Metastasis

France, Sweden, Italy, Denmark, Germany, Spain, Netherlands, Serbia, Austria, Switzerland, Belgium, United Kingdom
National Cancer Institute (NCI)

Recruiting

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Seoul National University Hospital
RF medical

Active, not recruiting

Radiofrequency Ablation for Recurrent Hepatocellular Carcinoma With Twin Cooled-wet Electrodes

Hepatocellular Carcinoma | Local Recurrence of Malignant Tumor of Liver

Korea, Republic of
M.D. Anderson Cancer Center

Recruiting

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Metastatic Renal Cell Carcinoma | Metastatic Melanoma | Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Bone | Metastatic Urothelial... and other conditions

United States
University of Edinburgh
Perspectum; Hampshire Hospitals NHS Foundation Trust

Completed

HepaT1ca: Quantifying Liver Health in Surgical Candidates for Liver Malignancies (Hepatica)

Surgery | Colorectal Cancer Metastatic | Liver Cancer | Liver Regeneration

United Kingdom
Northeastern Ohio Radiology Research and Education...

Withdrawn

Evaluation of Suspected Liver Pathology in Patients With Contraindications for Contrast Enhanced CT and/or MRI

Liver Metastasis | Liver Mass
Mark A Hull, PhD FRCP
Yorkshire Cancer Research; Amarin Pharma Inc.

Active, not recruiting

EPA for Metastasis Trial 2 (EMT2)

Colon Cancer | Liver Metastasis

United Kingdom
University of Florida
Merck Sharp & Dohme LLC

Recruiting

A Study of Oral IRAK-4 Inhibitor CA-4948 in Combination With Pembrolizumab Following Stereotactic Radiosurgery in Patients With Melanoma Brain Metastases

Melanoma Metastatic in the Brain

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Carcinoma in the Liver

United States
International Group of Endovascular Oncology

Completed

Observational Study on Second Line Treatment of Liver Metastases With DEBIRI and Cetuximab (TACETUX)

Colon Cancer Liver Metastasis

Italy
Hoffmann-La Roche

Completed

A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum

Colorectal Cancer

Taiwan
Hoffmann-La Roche

Completed

OBELIX Study: A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Cancer of the Colon or Rectum.

Colorectal Cancer

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Ipilimumab and Imatinib Mesylate in Advanced Cancer

Metastatic Melanoma | Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Melanoma | C-KIT Tyrosine Kinase Protein Overexpression | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Gastrointestinal Stromal Tumor | Pathologic Stage IV Cutaneous Melanoma... and other conditions

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Metastatic Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States, Canada
National Taiwan University Hospital

Unknown

Single Versus Multiple Fractionated SSRS for Spinal Metastases

Secondary Malignant Neoplasm of Spine

Taiwan
Hoffmann-La Roche

Completed

A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum.

Colorectal Cancer

Brazil
Hoffmann-La Roche

Completed

An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Cancer of the Colon or Rectum

Colorectal Cancer

Montenegro
Guangdong Provincial People's Hospital

Unknown

Compare FOFLOX4 in Preoperative and Postoperative and Postoperative in Resectable Liver Metastasis Colorectal Cancer (MCC)

Colorectal Cancer | Liver Metastasis

China
National Cancer Institute (NCI)

Active, not recruiting

Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Lung Neuroendocrine Neoplasm | Metastatic Malignant Neoplasm in the Brain | Metastatic Lung Small Cell Carcinoma

United States
Fudan University

Unknown

Study Comparing Radio Frequency Ablation Plus Chemotherapy and Chemotherapy Alone in Patients With Unresectable CRLM

Colorectal Cancer Liver Metastasis

China
Samsung Medical Center

Completed

Neoadjuvant FOLFOX6 + Cetuximab in Patients With Colorectal Cancer and Unresectable Liver Metastasis

Colorectal Cancer | Unresectable Liver Metastasis

Korea, Republic of
Mayo Clinic

Terminated

Measuring Cell Free DNA During the Course of Treatment for Esophageal Cancer as a Marker of Response and Recurrence

Esophageal Cancer | Cancer of the Esophagus | Esophageal Neoplasm | Esophagus Cancer | Cancer of Esophagus | Neoplasm, Esophageal | Esophageal Neoplasms Malignancy Unspecified | Esophageal Neoplasms Malignant

United States
Nuvation Bio Inc.

Withdrawn

Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC

Breast Cancer | Advanced Breast Cancer | Metastatic Breast Cancer | Breast Carcinoma | Cancer of Breast | Malignant Tumor of Breast | Breast Tumor | Cancer of the Breast

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Leptomeningeal Neoplasm | Recurrent Lung Non-Small Cell Carcinoma

United States
Dana-Farber Cancer Institute
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Brigham...

Active, not recruiting

Wide Excision Alone as Treatment for Ductal Carcinoma in Situ of The Breast

Ductal Carcinoma in Situ of the Breast

United States
Society of Interventional Oncology

Recruiting

Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM) (ACCLAIM)

Colorectal Liver Metastases

United States, Netherlands, Greece
Memorial Sloan Kettering Cancer Center

Completed

Assess the Feasibility of Cone Beam CT to Localize Liver Metastases Immediately Prior to Radiotherapy

Localize Liver Metastases

United States
Heidelberg University

Unknown

Effect of Neoadjuvant Radiation on Tumor Infiltrating T-cells by Low Dose Radiation in Colorectal Liver Metastases

Colorectal Liver Metastases

Germany
First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

TACE Plus HAIC Combined With Regorafenib for Liver Metastasis of Colorectal Cancer Refractory to Standard Treatment Regimens

Liver Metastasis Colon Cancer

China
University of Leeds
National Cancer Institute (NCI); Massachusetts General Hospital; Massachusetts... and other collaborators

Recruiting

Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases

Colon Cancer Liver Metastasis

United Kingdom
Sanofi

Withdrawn

Oxaliplatin and Capecitabine on Top of Sorafenib Versus Sorafenib Alone in Advanced Hepatocellular Carcinoma Patients (SECOX)

Hepatic Neoplasm Malignant
China Meitan General Hospital
Marino Biotechnology Co., Ltd.

Unknown

Chimeric Switch Receptor Modified T Cells for Patients With PD-L1+ Recurrent or Metastatic Malignant Tumors

Recurrent PD-L1+ Malignant Tumors | Metastatic PD-L1+ Malignant Tumors

China
Verastem, Inc.
Mirati Therapeutics Inc.

Recruiting

Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC Patients (RAMP204)

Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | Malignant Neoplasm of Lung | Malignant Neoplastic Disease | KRAS Activating Mutation

United States
Peking Union Medical College Hospital

Completed

The Efficacy and Safety of Anlotinib in Patients With Metastatic Pheochromocytoma or Paraganglioma

Paraganglioma, Extra-Adrenal | Malignant Adrenal Gland Pheochromocytoma | Malignant Paraganglioma | Pheochromocytoma, Metastatic | Paraganglioma, Malignant

China
Hospital Vall d'Hebron

Completed

Endoscopic Variceal Ligation in Children

Child | Endoscopy | Upper Gastrointestinal Bleeding | Esophageal Varices in Cirrhosis of the Liver
Royal Marsden NHS Foundation Trust

Unknown

Partial Liver Radiotherapy for Unresectable Liver Metastases

Metastatic Colorectal Liver Cancer

United Kingdom
University of Zurich

Completed

Impact of Pre-operative Bevacizumab on Complications After Resection of Colorectal Liver Metastases

Colorectal Liver Metastases

Switzerland, France, Spain
Zhongda Hospital

Not yet recruiting

Safety and Efficacy of Polyvinyl Alcohol Sodium Acrylate Embolization Microspheres for CRLM

Colorectal Cancer Liver Metastasis
Peking University People's Hospital
Peking University; Sanofi

Unknown

Phase 3 Study of Surgery Combined With Neoadjuvant Chemotherapy(XELOX) in Colorectal Cancer With Resectable Liver Metastasis

Colorectal Cancer | Resectable Liver Metastasis

China
American Regent, Inc.

Terminated

Taxoprexin® Treatment for Advanced Primary Cancers of the Liver

Cancer of the Liver

United States
Rigshospitalet, Denmark

Recruiting

Stereotactic Body Radiation Therapy vs. Microwave Ablation for Colorectal Cancer Patients With Metastatic Disease in the Liver

Liver Metastases | Colorectal Carcinoma

Denmark
Region Skane

Recruiting

On-treatment Biomarkers in Metastatic Colorectal Cancer for Life (On-CALL)

Metastatic Colorectal Cancer | Lung Metastases | Chemotherapy Effect | Peritoneal Metastases | Liver Metastasis Colon Cancer

Sweden
Fudan University

Recruiting

FOLFOXIRI Plus Cetuximab Versus FOLFOXIRI Plus Bevacizumab in Conversion Therapy of Right-sided Colon Cancer Liver Metastases

Liver Metastasis Colon Cancer

China
Aarhus University Hospital

Recruiting

Selective Internal Radiation Therapy With 90Y Resin Micropheres for Refractory Colorectal Cancer Liver Metastases (SIRT)

Liver Metastasis Colon Cancer

Denmark
Changhai Hospital

Recruiting

Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases

Colorectal Cancer | Metastatic Liver Cancer

China
EpicentRx, Inc.

Terminated

RRx-001 in Combination With Irinotecan in Metastatic or Advanced Cancer (PAYLOAD) (PAYLOAD)

Metastatic Cancer | Advanced Cancer | Malignant Solid Tumor

United States
Cho Ray Hospital
University of Medicine and Pharmacy at Ho Chi Minh City

Recruiting

Surgery Outcome Treated by Neo-adjuvant Combination of Oxaliplatin, Irinotecan, Folinic Acid and Fluorouracil (FOLFOXIRI) Regimen in Synchronous Liver Limited Metastasis Colorectal Cancer

Synchronous Neoplasm | Liver Metastasis Colon Cancer

Vietnam
University Health Network, Toronto

Not yet recruiting

Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction (ULTRAS)

Liver Metastases
Alpha Tau Medical LTD.

Recruiting

Alpha Radiation Emitters Device for the Treatment of Liver Metastases (DaRT)

Liver Metastases

Canada
M.D. Anderson Cancer Center

Recruiting

ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases

Liver Metastases

United States

Clinical Trials on Metastatic Malignant Neoplasm in the Liver

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ireland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations