Collection and Storage of Tissue and Blood Samples From Patients With Cancer

March 8, 2024 updated by: National Cancer Institute (NCI)

Patient-Derived Models Tissue Procurement Protocol for the National Cancer Institute (NCI)

This research trial collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer drugs.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

PRIMARY OBJECTIVE:

I. To procure biologic tissues and materials to generate preclinical models of cancer.

OUTLINE:

Tumor tissue and blood samples are procured during procedures that are required for the patients' clinical management and will be stored via xenograft (transplant to another species) models or in vitro cell culture for future analysis.

Study Type

Observational

Enrollment (Estimated)

5000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Alabama
      • Birmingham, Alabama, United States, 35233
        • Suspended
        • University of Alabama at Birmingham Cancer Center
    • Arkansas
      • Fort Smith, Arkansas, United States, 72903
        • Recruiting
        • Mercy Hospital Fort Smith
        • Contact:
          • Site Public Contact
          • Phone Number: 800-378-9373
        • Principal Investigator:
          • Jay W. Carlson
    • California
      • Arroyo Grande, California, United States, 93420
        • Active, not recruiting
        • PCR Oncology
      • Duarte, California, United States, 91010
        • Active, not recruiting
        • City of Hope Comprehensive Cancer Center
      • Los Angeles, California, United States, 90033
        • Active, not recruiting
        • USC / Norris Comprehensive Cancer Center
    • Colorado
      • Aurora, Colorado, United States, 80045
        • Active, not recruiting
        • UCHealth University of Colorado Hospital
    • Connecticut
      • New Haven, Connecticut, United States, 06510
        • Active, not recruiting
        • Smilow Cancer Center/Yale-New Haven Hospital
      • New Haven, Connecticut, United States, 06520
        • Active, not recruiting
        • Yale University
    • Delaware
      • Newark, Delaware, United States, 19713
        • Active, not recruiting
        • Helen F Graham Cancer Center
      • Newark, Delaware, United States, 19713
        • Active, not recruiting
        • Medical Oncology Hematology Consultants PA
      • Newark, Delaware, United States, 19713
        • Active, not recruiting
        • Delaware Clinical and Laboratory Physicians PA
      • Newark, Delaware, United States, 19718
        • Active, not recruiting
        • Christiana Care Health System-Christiana Hospital
      • Wilmington, Delaware, United States, 19801
        • Active, not recruiting
        • Christiana Care Health System-Wilmington Hospital
    • Georgia
      • Augusta, Georgia, United States, 30912
        • Recruiting
        • Augusta University Medical Center
        • Principal Investigator:
          • Sharad A. Ghamande
        • Contact:
    • Illinois
      • Bloomington, Illinois, United States, 61701
        • Active, not recruiting
        • Saint Joseph Medical Center
      • Bloomington, Illinois, United States, 61704
        • Suspended
        • Illinois CancerCare-Bloomington
      • Canton, Illinois, United States, 61520
        • Suspended
        • Illinois CancerCare-Canton
      • Carbondale, Illinois, United States, 62902
        • Suspended
        • Memorial Hospital of Carbondale
      • Carthage, Illinois, United States, 62321
        • Suspended
        • Illinois CancerCare-Carthage
      • Centralia, Illinois, United States, 62801
        • Suspended
        • Centralia Oncology Clinic
      • Chicago, Illinois, United States, 60612
        • Recruiting
        • John H Stroger Jr Hospital of Cook County
        • Contact:
          • Site Public Contact
          • Phone Number: 312-864-5204
        • Principal Investigator:
          • Thomas E. Lad
      • Decatur, Illinois, United States, 62526
        • Recruiting
        • Cancer Care Specialists of Illinois - Decatur
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • Decatur, Illinois, United States, 62526
        • Recruiting
        • Decatur Memorial Hospital
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • Effingham, Illinois, United States, 62401
        • Suspended
        • Crossroads Cancer Center
      • Eureka, Illinois, United States, 61530
        • Suspended
        • Illinois CancerCare-Eureka
      • Galesburg, Illinois, United States, 61401
        • Suspended
        • Western Illinois Cancer Treatment Center
      • Galesburg, Illinois, United States, 61401
        • Suspended
        • Illinois CancerCare-Galesburg
      • Kewanee, Illinois, United States, 61443
        • Suspended
        • Illinois CancerCare-Kewanee Clinic
      • Macomb, Illinois, United States, 61455
        • Suspended
        • Illinois CancerCare-Macomb
      • Mount Vernon, Illinois, United States, 62864
        • Recruiting
        • Good Samaritan Regional Health Center
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 618-242-4600
      • O'Fallon, Illinois, United States, 62269
        • Suspended
        • Cancer Care Center of O'Fallon
      • Ottawa, Illinois, United States, 61350
        • Suspended
        • Radiation Oncology of Northern Illinois
      • Ottawa, Illinois, United States, 61350
        • Suspended
        • Illinois CancerCare-Ottawa Clinic
      • Pekin, Illinois, United States, 61554
        • Suspended
        • OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
      • Pekin, Illinois, United States, 61554
        • Suspended
        • Illinois CancerCare-Pekin
      • Peoria, Illinois, United States, 61636
        • Suspended
        • Methodist Medical Center of Illinois
      • Peoria, Illinois, United States, 61615
        • Suspended
        • OSF Saint Francis Radiation Oncology at Peoria Cancer Center
      • Peoria, Illinois, United States, 61637
        • Suspended
        • OSF Saint Francis Medical Center
      • Peoria, Illinois, United States, 61615
        • Suspended
        • Illinois CancerCare-Peoria
      • Peru, Illinois, United States, 61354
        • Suspended
        • Valley Radiation Oncology
      • Peru, Illinois, United States, 61354
        • Suspended
        • Illinois CancerCare-Peru
      • Princeton, Illinois, United States, 61356
        • Suspended
        • Illinois CancerCare-Princeton
      • Springfield, Illinois, United States, 62781
        • Suspended
        • Memorial Medical Center
      • Springfield, Illinois, United States, 62702
        • Active, not recruiting
        • Central Illinois Hematology Oncology Center
      • Springfield, Illinois, United States, 62702
        • Suspended
        • Springfield Clinic
      • Springfield, Illinois, United States, 62702
        • Suspended
        • Southern Illinois University School of Medicine
    • Kansas
      • Chanute, Kansas, United States, 66720
        • Suspended
        • Cancer Center of Kansas - Chanute
      • Dodge City, Kansas, United States, 67801
        • Suspended
        • Cancer Center of Kansas - Dodge City
      • El Dorado, Kansas, United States, 67042
        • Suspended
        • Cancer Center of Kansas - El Dorado
      • Fort Scott, Kansas, United States, 66701
        • Suspended
        • Cancer Center of Kansas - Fort Scott
      • Independence, Kansas, United States, 67301
        • Suspended
        • Cancer Center of Kansas-Independence
      • Kingman, Kansas, United States, 67068
        • Suspended
        • Cancer Center of Kansas-Kingman
      • Lawrence, Kansas, United States, 66044
        • Suspended
        • Lawrence Memorial Hospital
      • Liberal, Kansas, United States, 67905
        • Suspended
        • Cancer Center of Kansas-Liberal
      • Manhattan, Kansas, United States, 66502
        • Suspended
        • Cancer Center of Kansas-Manhattan
      • Newton, Kansas, United States, 67114
        • Suspended
        • Cancer Center of Kansas - Newton
      • Parsons, Kansas, United States, 67357
        • Suspended
        • Cancer Center of Kansas - Parsons
      • Pratt, Kansas, United States, 67124
        • Suspended
        • Cancer Center of Kansas - Pratt
      • Salina, Kansas, United States, 67401
        • Suspended
        • Cancer Center of Kansas - Salina
      • Wellington, Kansas, United States, 67152
        • Suspended
        • Cancer Center of Kansas - Wellington
      • Wichita, Kansas, United States, 67208
        • Suspended
        • Associates In Womens Health
      • Wichita, Kansas, United States, 67214
        • Recruiting
        • Cancer Center of Kansas - Wichita
        • Contact:
        • Principal Investigator:
          • Dennis F. Moore
      • Wichita, Kansas, United States, 67208
        • Suspended
        • Cancer Center of Kansas-Wichita Medical Arts Tower
      • Wichita, Kansas, United States, 67214
        • Suspended
        • Ascension Via Christi Hospitals Wichita
      • Wichita, Kansas, United States, 67214
        • Suspended
        • Wesley Medical Center
      • Winfield, Kansas, United States, 67156
        • Suspended
        • Cancer Center of Kansas - Winfield
    • Maryland
      • Baltimore, Maryland, United States, 21287
        • Active, not recruiting
        • Johns Hopkins University/Sidney Kimmel Cancer Center
    • Massachusetts
      • Boston, Massachusetts, United States, 02215
        • Active, not recruiting
        • Dana-Farber Cancer Institute
    • Michigan
      • Ann Arbor, Michigan, United States, 48106
        • Active, not recruiting
        • Saint Joseph Mercy Hospital
      • Battle Creek, Michigan, United States, 49017
        • Suspended
        • Bronson Battle Creek
      • Grand Rapids, Michigan, United States, 49503
        • Recruiting
        • Spectrum Health at Butterworth Campus
        • Contact:
        • Principal Investigator:
          • Kathleen J. Yost
      • Grand Rapids, Michigan, United States, 49503
        • Suspended
        • Trinity Health Grand Rapids Hospital
      • Kalamazoo, Michigan, United States, 49048
        • Suspended
        • Borgess Medical Center
      • Kalamazoo, Michigan, United States, 49007
        • Suspended
        • West Michigan Cancer Center
      • Livonia, Michigan, United States, 48154
        • Active, not recruiting
        • Trinity Health Saint Mary Mercy Livonia Hospital
      • Muskegon, Michigan, United States, 49444
        • Suspended
        • Trinity Health Muskegon Hospital
      • Niles, Michigan, United States, 49120
        • Suspended
        • Corewell Health Lakeland Hospitals - Niles Hospital
      • Reed City, Michigan, United States, 49677
        • Suspended
        • Corewell Health Reed City Hospital
      • Saint Joseph, Michigan, United States, 49085
        • Suspended
        • Lakeland Medical Center Saint Joseph
      • Saint Joseph, Michigan, United States, 49085
        • Suspended
        • Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
      • Traverse City, Michigan, United States, 49684
        • Suspended
        • Munson Medical Center
    • Minnesota
      • Rochester, Minnesota, United States, 55905
        • Active, not recruiting
        • Mayo Clinic in Rochester
    • Mississippi
      • Oxford, Mississippi, United States, 38655
        • Recruiting
        • Baptist Memorial Hospital and Cancer Center-Oxford
        • Contact:
        • Principal Investigator:
          • Raymond U. Osarogiagbon
    • Missouri
      • Bolivar, Missouri, United States, 65613
        • Suspended
        • Central Care Cancer Center - Bolivar
      • Bonne Terre, Missouri, United States, 63628
        • Suspended
        • Parkland Health Center-Bonne Terre
      • Branson, Missouri, United States, 65616
        • Suspended
        • Cox Cancer Center Branson
      • Cape Girardeau, Missouri, United States, 63703
        • Suspended
        • Southeast Cancer Center
      • Cape Girardeau, Missouri, United States, 63703
        • Suspended
        • Saint Francis Medical Center
      • Jefferson City, Missouri, United States, 65109
        • Suspended
        • Capital Region Southwest Campus
      • Joplin, Missouri, United States, 64804
        • Recruiting
        • Freeman Health System
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
      • Joplin, Missouri, United States, 64804
        • Recruiting
        • Mercy Hospital Joplin
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
      • Rolla, Missouri, United States, 65401
        • Suspended
        • Mercy Clinic-Rolla-Cancer and Hematology
      • Rolla, Missouri, United States, 65401
        • Recruiting
        • Delbert Day Cancer Institute at PCRMC
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
      • Saint Joseph, Missouri, United States, 64506
        • Recruiting
        • Heartland Regional Medical Center
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
      • Saint Louis, Missouri, United States, 63141
        • Recruiting
        • Mercy Hospital Saint Louis
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 314-251-7066
      • Saint Louis, Missouri, United States, 63131
        • Recruiting
        • Missouri Baptist Medical Center
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
          • Site Public Contact
          • Phone Number: 314-996-5569
      • Saint Louis, Missouri, United States, 63109
        • Suspended
        • Saint Louis Cancer and Breast Institute-South City
      • Saint Louis, Missouri, United States, 63128
        • Recruiting
        • Mercy Hospital South
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
      • Saint Louis, Missouri, United States, 63110
        • Suspended
        • Washington University School of Medicine
      • Sainte Genevieve, Missouri, United States, 63670
        • Suspended
        • Sainte Genevieve County Memorial Hospital
      • Springfield, Missouri, United States, 65804
        • Recruiting
        • Mercy Hospital Springfield
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 417-269-4520
      • Springfield, Missouri, United States, 65807
        • Recruiting
        • CoxHealth South Hospital
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 417-269-4520
      • Sullivan, Missouri, United States, 63080
        • Suspended
        • Missouri Baptist Sullivan Hospital
      • Sunset Hills, Missouri, United States, 63127
        • Suspended
        • BJC Outpatient Center at Sunset Hills
    • Nevada
      • Henderson, Nevada, United States, 89052
        • Active, not recruiting
        • Cancer and Blood Specialists-Henderson
      • Las Vegas, Nevada, United States, 89148
        • Active, not recruiting
        • OptumCare Cancer Care at Fort Apache
      • Las Vegas, Nevada, United States, 89106
        • Active, not recruiting
        • Cancer and Blood Specialists-Shadow
      • Las Vegas, Nevada, United States, 89109
        • Active, not recruiting
        • HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
      • Las Vegas, Nevada, United States, 89113
        • Active, not recruiting
        • HealthCare Partners Medical Group Oncology/Hematology-San Martin
      • Las Vegas, Nevada, United States, 89121
        • Active, not recruiting
        • Cancer Therapy and Integrative Medicine
      • Las Vegas, Nevada, United States, 89128
        • Active, not recruiting
        • Cancer and Blood Specialists-Tenaya
      • Las Vegas, Nevada, United States, 89128
        • Active, not recruiting
        • HealthCare Partners Medical Group Oncology/Hematology-Tenaya
      • Las Vegas, Nevada, United States, 89148
        • Active, not recruiting
        • Comprehensive Cancer Centers of Nevada
      • Las Vegas, Nevada, United States, 89149
        • Active, not recruiting
        • HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
      • Las Vegas, Nevada, United States, 89169
        • Active, not recruiting
        • Comprehensive Cancer Centers of Nevada - Central Valley
    • New York
      • Bronx, New York, United States, 10461
        • Active, not recruiting
        • Montefiore Medical Center-Einstein Campus
      • Bronx, New York, United States, 10461
        • Active, not recruiting
        • Montefiore Medical Center-Weiler Hospital
      • Bronx, New York, United States, 10467
        • Active, not recruiting
        • Montefiore Medical Center - Moses Campus
      • New York, New York, United States, 10032
        • Recruiting
        • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
        • Principal Investigator:
          • Bret Taback
        • Contact:
    • North Carolina
      • Chapel Hill, North Carolina, United States, 27599
        • Suspended
        • UNC Lineberger Comprehensive Cancer Center
      • Durham, North Carolina, United States, 27710
        • Active, not recruiting
        • Duke University Medical Center
    • Oklahoma
      • Oklahoma City, Oklahoma, United States, 73120
        • Recruiting
        • Mercy Hospital Oklahoma City
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 405-752-3402
    • Tennessee
      • Memphis, Tennessee, United States, 38120
        • Recruiting
        • Baptist Memorial Hospital and Cancer Center-Memphis
        • Contact:
        • Principal Investigator:
          • Raymond U. Osarogiagbon
    • Texas
      • Houston, Texas, United States, 77030
        • Active, not recruiting
        • M D Anderson Cancer Center
    • Washington
      • Auburn, Washington, United States, 98001
        • Active, not recruiting
        • MultiCare Auburn Medical Center
      • Bainbridge Island, Washington, United States, 98110
        • Active, not recruiting
        • Virginia Mason Bainbridge Island Medical Center
      • Federal Way, Washington, United States, 98002
        • Active, not recruiting
        • Virginia Mason Federal Way Medical Center
      • Gig Harbor, Washington, United States, 98335
        • Active, not recruiting
        • MultiCare Gig Harbor Medical Park
      • Lynnwood, Washington, United States, 98036
        • Active, not recruiting
        • Virginia Mason Lynnwood Medical Center
      • Puyallup, Washington, United States, 98372
        • Active, not recruiting
        • MultiCare Good Samaritan Hospital
      • Seattle, Washington, United States, 98101
        • Active, not recruiting
        • Virginia Mason Medical Center
    • Wisconsin
      • Chippewa Falls, Wisconsin, United States, 54729
        • Active, not recruiting
        • Marshfield Clinic-Chippewa Center
      • Eau Claire, Wisconsin, United States, 54701
        • Active, not recruiting
        • Marshfield Clinic Cancer Center at Sacred Heart
      • La Crosse, Wisconsin, United States, 54601
        • Suspended
        • Gundersen Lutheran Medical Center
      • Marshfield, Wisconsin, United States, 54449
        • Active, not recruiting
        • Marshfield Medical Center-Marshfield
      • Minocqua, Wisconsin, United States, 54548
        • Active, not recruiting
        • Marshfield Clinic-Minocqua Center
      • Rice Lake, Wisconsin, United States, 54868
        • Active, not recruiting
        • Marshfield Medical Center-Rice Lake
      • Stevens Point, Wisconsin, United States, 54481
        • Active, not recruiting
        • Ascension Saint Michael's Hospital
      • Wausau, Wisconsin, United States, 54401
        • Active, not recruiting
        • Marshfield Clinic-Wausau Center
      • Weston, Wisconsin, United States, 54476
        • Active, not recruiting
        • Marshfield Medical Center - Weston

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Patients undergoing evaluation and/or treatment for cancer

Description

Inclusion Criteria:

  • Patients 18 year of age or older who are being evaluated, treated, or enrolled in a clinical trial for cancer at participating sites
  • Patients with a histologically or cytologically confirmed diagnosis of cancer

  • Patients without histologically or cytologically confirmed diagnosis of cancer, but for whom approval has been requested and received from the coordinating site study coordinator

    • Requests for coordinating site approval should only be made if the patient's existing work-up at the time of the request demonstrates a combination of two or more of the following indicating the greater likelihood of a cancerous process in the assessment of the treating physician:

      • Radiographic imaging (computed tomography [CT], magnetic resonance imaging [MRI], etc.)
      • Elevated tumor markers
      • Clinical symptoms
      • Documented risk factors, known genetic changes (mutation, deletion, fusion, etc.), and/or known familial cancer history or syndrome
      • Complete blood count (CBC) w/differential indicative of a probable hematologic malignancy
    • If the patient will be undergoing surgical resection at a later time and will be accessible to approach for study participation at that time, resected material following cancer diagnosis confirmation is preferred
    • Important: Additional medical, genetic and/or demographic work-up should not be obtained solely for determination of eligibility for protocol 9846 by these criteria. Once available, final histology must be confirmed to the coordinating site detailing the cancer diagnosis for patients enrolled based on the above criteria
  • Patients with a newly diagnosed primary and/or metastatic solid tumor or hematologic malignancy for which they have not yet received treatment

  • Patients with a solid tumor or hematologic malignancy that is recurrent, newly metastasized, or progressing while on treatment indicated by:

    • Radiographic evidence of tumor growth, re-growth, and/or new metastases, OR
    • Documentation by the treating physician of clinical disease progression, OR
    • CBC w/differential and/or flow cytometry for hematologic malignancies

  • Patients currently undergoing treatment (adjuvant, neoadjuvant, etc.)

    • Specimen collection should occur as distant in time from the most recent drug administration as possible (e.g., after completion of a treatment cycle and immediately prior to initiation of the next cycle)
    • Specimens should not be collected from patients between doses within a single treatment cycle
    • Confirmation of viable residual malignancy and/or < 90% tumor necrosis, fibrosis, or hemorrhage must be confirmed to the National Cancer Institute (NCI) coordinating site, as indicated in the final post-operative/post-procedure pathology and/or flow cytometry report

  • Patients with ongoing partial response (PR) or stable disease (SD) are eligible

    • Confirmation of viable malignancy and/or < 90% tumor necrosis, fibrosis, or hemorrhage must be confirmed to the NCI coordinating site, as indicated in the final post-operative/post-procedure pathology and/or flow cytometry report
  • Ability to understand and willingness to sign a written informed consent document indicating their willingness to have their tissue or biologic fluid specimens used for research as outlined in this protocol

Exclusion Criteria:

  • Patients with cancer-like syndromes and/or blood disorders such as systemic mastocytosis, Langerhans cell histiocytosis, chronic eosinophilic leukemia/hypereosinophilic syndrome, lymphomatoid granulomatosis, or monoclonal gammopathy of undetermined significance (MGUS)
  • Patients with invasive fungal infections

  • Patients with active and/or uncontrolled bacterial, fungal, or viral infections or who are still recovering from an infection

    • Actively febrile patients with uncertain etiology of febrile episode
    • All antibiotics prescribed for the treatment of a bacterial infection should be completed at least 1 week (7 days) prior to collection
    • No recurrence of fever or other symptoms related to infection for at least 1 week (7 days) following completion of antibiotics
    • Patients receiving antibiotics, antifungals, and/or antivirals for prophylaxis are permissible
    • Antibiotics being administered topically at a location distant from the planned tissue collection site or eye drops for a localized infection are permissible
  • Patients with human immunodeficiency virus (HIV), active or chronic hepatitis (i.e., quantifiable hepatitis B virus [HBV]-deoxyribonucleic acid [DNA] and/or positive hepatitis B surface antigen [HbsAg], quantifiable hepatitis C virus [HCV]-ribonucleic acid [RNA]) or known history of HCV, HBV, or HIV; testing for HBV, HCV, HIV or other infections for eligibility will be performed only if clinically indicated

  • Patients with hepatitis A as indicated by anti-hepatitis A virus (HAV) IgM reactivity

    • Patients that are anti-HAV IgG reactive only are eligible
  • Specimen collections from patients with benign tumors including but not limited to desmoid tumors, carcinoma in situ, or ongoing evidence of complete disease response (CR)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Only
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Ancillary-correlative (tissue and blood procurement)
Tumor tissue and blood samples are procured during procedures that are required for the patients' clinical management and stored via xenograft (transplant to another species) models or in vitro cell culture for future analysis.
Other: Cytology Specimen Collection Procedure
Procurement of tissue and blood samples
Other Names:
  • Cytologic Sampling

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Procurement of tissue and blood specimens for research purposes
Time Frame: Up to 5 years
Tissues and venous blood will be stored, implanted immediately to generate patient-derived xenografts (which require fresh, viable cells), or placed immediately into in vitro cell culture to generate patient-derived cell lines (which require fresh, viable cells).
Up to 5 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Cancer Institute (NCI)

Investigators

  • Principal Investigator: James H Doroshow, National Cancer Institute (NCI)

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 19, 2015

Primary Completion (Estimated)

May 4, 2024

Study Completion (Estimated)

May 4, 2024

Study Registration Dates

First Submitted

June 15, 2015

First Submitted That Met QC Criteria

June 15, 2015

First Posted (Estimated)

June 17, 2015

Study Record Updates

Last Update Posted (Actual)

March 12, 2024

Last Update Submitted That Met QC Criteria

March 8, 2024

Last Verified

December 1, 2023

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • NCI-2015-00863 (Registry Identifier: CTRP (Clinical Trial Reporting Program))
  • UM1CA186689 (U.S. NIH Grant/Contract)
  • UM1CA186691 (U.S. NIH Grant/Contract)
  • UM1CA186704 (U.S. NIH Grant/Contract)
  • ZIABC011078 (U.S. NIH Grant/Contract)
  • UM1CA186717 (U.S. NIH Grant/Contract)
  • UM1CA186709 (U.S. NIH Grant/Contract)
  • P9846
  • P9846_R02PAPPHOLD01
  • 9846 (Other Identifier: CTEP)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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