Clinical Trials on Metastatic Unresectable Sarcoma

Total 12200 results

University Hospital, Strasbourg, France

Recruiting

Bipolar RFA of Painful Extra-spinal Bone Metastases (PERFACOOL)

Multi-metastatic Cancer

France
Capital Medical University
Duke University

Withdrawn

Personalized Vaccine Generated by Autologous Dendritic Cells Pulsed With Autologous Whole Tumor Cell Lysate Treat Advanced Solid Tumor Patients With High Tumor Mutation Burden

Metastatic Cancer | Advanced Cancer

China
Array Biopharma, now a wholly owned subsidiary...

Completed

A Study of ARRY-382 in Patients With Selected Advanced or Metastatic Cancers

Metastatic Cancer

United States
Mayo Clinic

Completed

Radiofrequency Ablation in Relieving Pain in Patients With Bones Metastases

Pain | Metastatic Cancer

United States
Immodulon Therapeutics Ltd

Terminated

Study of IMM 101 in Combination With Standard of Care in Patients With Metastatic or Unresectable Cancer (MODULATE)

Metastatic Cancer

France, United Kingdom
Alethia Biotherapeutics

Completed

Phase I Dose Escalation Study of AB-16B5 in Subjects With an Advanced Solid Malignancy

Solid Tumor | Metastatic Cancer

Canada
UNICANCER

Completed

Study With Pazopanib in Combination With Cisplatin (CDDP) in Patients With Advanced Solid Tumors (PACIFIK)

Metastatic Cancer | Solid Tumors

France
Shanghai Runshi Pharmaceutical Technology Co., Ltd
Jilin Provincial Tumor Hospital

Recruiting

A Study to Investigate the Safety of SYHA1815 in Subjects With Unresectable Locally Advanced or Metastatic Solid Tumors

Locally Advanced Unresectable Carcinoma

China
National Cancer Institute (NCI)

Withdrawn

Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy

Melanoma | Sarcoma | Neoplasms, Germ Cell and Embryonal | Neoplasm Metastasis
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Terminated

Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With Uterine Cancer

Uterine Carcinosarcoma | Stage IIA Uterine Sarcoma | Stage IIB Uterine Sarcoma | Stage IIIA Uterine Sarcoma | Stage IIIB Uterine Sarcoma | Stage IIIC Uterine Sarcoma | Stage IVA Uterine Sarcoma | Stage IVB Uterine Sarcoma | Stage IA Uterine Sarcoma | Stage IB Uterine Sarcoma | Stage IC Uterine Sarcoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
Mayo Clinic

Recruiting

Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma

Soft Tissue Sarcoma | Bone Sarcoma

United States
Jazz Pharmaceuticals

Recruiting

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma (EMERGE 101)

Ewing Sarcoma | Refractory Ewing Sarcoma | Relapsed Ewing Sarcoma

United States, Canada
Foghorn Therapeutics Inc.

Terminated

FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors

Advanced Synovial Sarcoma

United States, Spain, France, Italy
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

A Trial of Cediranib in the Treatment of Patients With Alveolar Soft Part Sarcoma (CASPS) (CASPS)

Alveolar Soft-part Sarcoma

Australia, United Kingdom, Spain
Ohio State University Comprehensive Cancer Center

Recruiting

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Spine

United States
Wake Forest University Health Sciences
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Efficacy of Doxorubicin and Pembrolizumab for Sarcoma

Soft Tissue Sarcoma, Adult | Soft Tissue Sarcoma, Child

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Withdrawn

Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Primary or Recurrent Sarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IVA Adult Soft Tissue Sarcoma | Stage IIB Adult Soft Tissue Sarcoma | Stage IIC Adult Soft Tissue Sarcoma

United States, Canada
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Terminated

Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy and Chemotherapy For Patients With High-Grade or Intermediate-Grade Primary Soft Tissue Sarcoma of the Arm, Leg, or Body Wall

Recurrent Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma AJCC v7 | Stage II Adult Soft Tissue Sarcoma AJCC v7 | Stage III Adult Soft Tissue Sarcoma AJCC v7

United States
Institut Bergonié

Recruiting

Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients (PIPER)

Soft Tissue Sarcoma Adult | Solitary Fibrous Tumors | Hemangioendothelioma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Epithelioid Sarcoma | Desmoplastic Round Cell Tumor

France
Dana-Farber Cancer Institute
Merck Sharp & Dohme LLC

Suspended

Pembrolizumab in Neoplasms or Lymphomas

Lymphoma | Histiocytic Sarcoma | Follicular Dendritic Cell Sarcoma | Interdigitating Dendritic Cell Sarcoma

United States
Daiichi Sankyo
AstraZeneca

Recruiting

A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)

Metastatic Cancer | Advanced Cancer

Spain, Korea, Republic of, Belgium, Italy, France, United States, Australia, Japan, Taiwan, United Kingdom
Memorial Sloan Kettering Cancer Center
Repare Therapeutics

Recruiting

A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer

Solid Tumor | Metastatic Cancer

United States
Qurient Co., Ltd.
Merck Sharp & Dohme LLC

Recruiting

Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

Metastatic Cancer | Advanced Cancer

United States, Korea, Republic of
Imperial College London
Curesponse Ltd.

Not yet recruiting

Prediction of Drug Response Using an Ex Vivo Organ Culture (EVOC) on Fresh Human Tumour Samples From Metastatic Patients (CURESPONSE)

Metastatic Cancer | Advanced Cancer
Poitiers University Hospital

Recruiting

Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients

Metastatic Colon Cancer

France
Meryx, Inc.

Active, not recruiting

Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors

Pathologic Processes | Neoplasms | Neoplasm Metastasis | Neoplastic Processes | Metastatic Cancer | Advanced Cancer

United States
Samsung Medical Center

Completed

Clinical Sequencing Project for Metastatic Cancer Patients for Personalized Cancer Clinic.

Colorectal Cancer

Korea, Republic of
P.O. Witteveen
Erasmus Medical Center; The Netherlands Cancer Institute

Terminated

CPCT-05 Biopsy Protocol Patient Selection

Solid Tumors | Metastatic Disease

Netherlands
Virginia Commonwealth University

Terminated

Randomized RT +/- Lapatinib for Advanced Solid Tumor Cancer Patients Receiving Radiation Therapy for Metastatic Disease

Epithelial Cancer

United States
University of Chicago
Genentech, Inc.

Completed

Rapamycin Plus Bevacizumab in Advanced Cancers

Metastatic Cancer | Advanced Cancer

United States
Centre Leon Berard
Novartis; Roche Pharma AG; Fondation Apicil; Malakoff-Humanis; Fédération Leucémie... and other collaborators

Recruiting

A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors. (PASCA)

Acute Myeloid Leukemia | Hodgkin Disease | Osteosarcoma | Non Hodgkin Lymphoma | Late Effects | Ewing's Sarcoma | Testicular Germ Cell Tumor Mixed | Non-Metastatic Breast Carcinoma | Soft Tissue Sarcoma, Adult, Stage IIC

France
University of Washington
National Cancer Institute (NCI)

Completed

Pazopanib Hydrochloride Followed by Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma

Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage IIA Adult Soft Tissue Sarcoma

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

Osteosarcoma | Chondrosarcoma | Bone Neoplasm | Bone Sarcoma | Ewing's Sarcoma | Osseous Sarcoma

United States
Centre Leon Berard

Recruiting

MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma (COTESARC)

Sarcoma,Soft Tissue

France
Xiangya Hospital of Central South University

Active, not recruiting

Efficacy and Safety Study of Cardunilizumab in Soft Tissue Sarcoma

Sarcoma, Soft Tissue

China
Istituto Ortopedico Rizzoli

Completed

Analysis of the Molecular Profile of the Mixofibrosarcoma of the Extremities (MFS)

Sarcoma,Soft Tissue

Italy
Fox Chase Cancer Center

Terminated

Study of TAK-228 (MLN0128) in Soft Tissue Sarcomas

Soft-tissue Sarcoma

United States
Eisai Co., Ltd.

Completed

A Study on Safety and Efficacy in Patients With Soft Tissue Sarcomas (HAL03T)

Sarcoma, Soft Tissue

Japan
Eli Lilly and Company

Completed

A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma

Sarcoma, Soft Tissue

United States
Italian Sarcoma Group

Completed

Retrospective Study of Trabectedin in Soft Tissue Sarcomas (TrObs)

Sarcoma, Soft Tissue

Italy
Institut de Cancérologie de Lorraine

Completed

A Study to Compare Adjuvant Concurrent Chemoradiation (CCRT) to Adjuvant Radiation Therapy (RT) in Grade 2 and 3 Extremity Soft Tissue Sarcomas

Sarcoma,Soft Tissue
University of Michigan Rogel Cancer Center

Completed

Evaluation of Side Effects and Relative Activity of Two Chemotherapy Regimens in the Treatment Soft Tissue Sarcoma

Sarcoma, Soft Tissue

United States
GlaxoSmithKline

Completed

Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy (PALETTE)

Sarcoma, Soft Tissue

United States, Australia, Germany, Spain, Belgium, Sweden, France, Korea, Republic of, Italy, Netherlands, Japan, United Kingdom, Denmark
Istituto Clinico Humanitas

Completed

BAY-43-9006 in Advanced, Metastatic Soft Tissue Sarcomas

Sarcoma, Soft Tissue

Italy
Assistance Publique - Hôpitaux de Paris

Unknown

Phase II Multicentric Study of Digoxin Per os in Classic or Endemic Kaposi' s Sarcoma (KADIG 01)

Kaposi' s Sarcoma | Classic Kaposi' s Sarcoma | Endemic Kaposi' s Sarcoma | Lymph Angio Proliferations

France
Iovance Biotherapeutics, Inc.

Recruiting

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

Melanoma | Metastatic Melanoma | Unresectable Melanoma

United States, Spain, Australia, France, Netherlands, Italy, Canada, Sweden
BioNTech US Inc.

Recruiting

NEO-PTC-01 in Patients With Advanced or Metastatic Melanoma

Metastatic Melanoma | Unresectable Melanoma

Belgium, Netherlands, Spain
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

NY-ESO-1 Specific T Cells After Cyclophosphamide in Treating Patients With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Myxoid/Round Cell Liposarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Adult Synovial Sarcoma

United States
Hitendra Patel
Cancer Research UK; Stand Up To Cancer; Lustgarten Foundation; HonorHealth Research... and other collaborators

Withdrawn

High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | Pancreas Cancer | Metastatic Pancreatic Cancer | Pancreatic Adenocarcinoma Resectable | Pancreatic Metastasis

United States

Clinical Trials on Metastatic Unresectable Sarcoma

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