Clinical Trials on Mild Cognitive Impairment in Canada

Total 446 results

University of Calgary
Sport Science Association of Alberta (SSAA)

Unknown

Treatment for Achilles Tendinopathy

Achilles Tendinopathy | Achilles Tendon Enthesopathy | Mid-Portion Achilles Tendinopathy | Insertional Achilles Tendinopathy | Non-Insertional Achilles Tendinopathy

Canada
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS-MAPTRx in Patients With Mild Alzheimer's Disease

Mild Alzheimer's Disease

United Kingdom, Netherlands, Germany, Sweden, Canada, Finland
University of Alberta

Active, not recruiting

Edmonton Dyspnea Inventory- Validation Study

ILD

Denmark, Canada, United Kingdom
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR)

Unknown

Renal Hypothermia During Partial Nephrectomy

Kidney Cancer | Kidney Diseases | Urologic Diseases | Cancer | Renal Impairment | Hypothermia

Canada
Allergan

Active, not recruiting

A Study to Assess Adverse Events and Change in Disease Activity of HArmonyCa Lidocaine Injectable Gel for Mid Face Soft Tissue Augmentation in Adult Participants

Mid Face Volume Deficit

Canada, Spain, United Kingdom
West Park Healthcare Centre
St. Joseph's Healthcare Hamilton

Recruiting

A Non-pharmacological Cough Control Therapy

Cough | Pulmonary Fibrosis | Pulmonary Disease | ILD

Canada
University of British Columbia
Harvard Medical School (HMS and HSDM)

Active, not recruiting

Rehabilitation for Functional Memory Symptoms After Concussion

Mild Traumatic Brain Injury | Functional Neurological Disorder

Canada
Marie-Josée Brouillette
Fonds de la Recherche en Santé du Québec; CIHR Canadian HIV Trials Network

Terminated

COMO: Cognition Study With HIV+ Patients (CTNPT 015) (COMO)

HIV - Human Immunodeficiency Virus | Cognitive Symptoms

Canada
University of Alberta

Recruiting

Nutritional Management of Post COVID-19 Cognitive Symptoms

Long COVID

Canada
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Active, not recruiting

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Tricuspid Regurgitation | Mild Tricuspid Regurgitation | Moderate Tricuspid Regurgitation

United States, Canada, Germany
University of Calgary

Recruiting

Treatment of Post-concussion Syndrome With TMS: Using FNIRS as a Biomarker of Response

Transcranial Magnetic Stimulation | Post-Concussion Syndrome | Post-traumatic Stress Disorder | Mild Traumatic Brain Injury | Concussion | Functional Near-Infrared Spectroscopy

Canada
Assembly Biosciences

Terminated

ABI-M201 in Adult Subjects With Mildly-to-Moderately Active Ulcerative Colitis

Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic Mild

United States, Canada
University of North Carolina, Chapel Hill
ADD Centre© and Biofeedback Institute of Toronto©

Completed

The Listening Project at the ADD Centre and Biofeedback Institute of Toronto

Stress Disorder | Auditory Perceptual Disorders

Canada
Novartis

Completed

A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study (RESTORE)

Diabetic Macular Edema

Greece, Belgium, Spain, France, Netherlands, Australia, Canada, Germany, Hungary, Italy, Switzerland, Turkey, United Kingdom
GAAD Medical Research Institute Inc.

Unknown

Far Infrared Irradiation for Managing, Control and Treatment of Huntington's Disease (HD)

Huntington Disease

Canada
York University
North York General Hospital

Completed

Working Memory Training in Huntington's Disease

Huntington's Disease

Canada
University Health Network, Toronto
Canadian Cancer Trials Group; Young Investigator Award - American Society of... and other collaborators

Completed

Cognitive Function and Fatigue in Colorectal Cancer (CRC) Patients After Chemotherapy

Fatigue | Colorectal Neoplasm | Cognition

Canada, Australia
Prollenium Medical Technologies Inc.

Completed

A Study to Evaluate the Safety and Efficacy of Revanesse Shape + With Lidocaine Versus Juvederm Voluma With Lidocaine for the Correction of Age-Related Midface Volume Deficit / Lipoatrophy at 6 and 12 Months Post-treatment

Volume Deficit in the Mid-face

Canada
University of British Columbia
Huntington Study Group; Huntington Society of Canada

Completed

A Trial of Memantine as Symptomatic Treatment for Early Huntington Disease (MITIGATE-HD)

Huntington Disease

Canada
Bayer

Completed

Safety of Gadovist in Renally Impaired Patients (GRIP)

Fibrosis | Renal Impairment

Italy, Spain, Korea, Republic of, Germany, Canada, France, Austria, Thailand, Australia, Switzerland
Biosearch S.A.

Recruiting

Effect of Probiotics Consumed During Pregnancy on the Incidence of Mastitis

Women's Health | Lactation | Mastitis | Breast Milk | Infant Health

Spain
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, Canada, Denmark, France, Italy, Saudi Arabia, Switzerland, Australia, Finland, Netherlands, Sweden, Norway, United Arab Emirates, Japan, United Kingdom
Lundbeck Canada Inc.

Completed

Assessment in Work Productivity and the Relationship With Cognitive Symptoms in Patients With MDD Taking Vortioxetine (AtWoRC)

Major Depressive Disorder

Canada
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab (Intravitreal Injections) Versus Laser Treatment in Patients With Visual Impairment Due to Diabetic Macular Edema (RED-ES)

Diabetic Macular Edema | Visual Impairment

Spain
Neurocrine Biosciences

Enrolling by invitation

Long-term Study to Evaluate Safety and Tolerability of Valbenazine in Participants With Chorea Associated With Huntington Disease in Canada

Chorea, Huntington

Canada
Guerbet
Bayer AG (Sponsor); Bracco (Sponsor); GEHC (Sponsor)

Recruiting

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years (ODYSSEY)

Cognitive Function | Motor Function | Contrast Media

United States, Korea, Republic of, Italy, Brazil, Canada, Russian Federation
InSightec

Active, not recruiting

ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders

Parkinson's Disease | Movement Disorders | Tardive Dyskinesia | Dystonia | Essential Tremor | Huntington's Disease | Wilson's Disease | Holmes Tremor | Orofacial Dyskinesias

Canada
Celgene

Completed

Study of Pomalidomide to Evaluate the Pharmacokinetics and Safety for Patients With Multiple Myeloma and Impaired Renal Function (POM Renal) (POM Renal)

Multiple Myeloma | Renal Impairment

United States, Canada
Wake Forest University
National Institute on Aging (NIA)

Completed

Cognition in the Study of Tamoxifen and Raloxifene (Co-STAR)

Aging | Cognition

United States, Canada
CHDI Foundation, Inc.
The University of Texas Health Science Center, Houston; Dr. Glenn T. Stebbins... and other collaborators

Completed

FuRST 2.0 Cognitive Pre-Testing

Huntington's Disease

United States, Canada
CHDI Foundation, Inc.
Dr. Glenn T. Stebbins (Rush University Medical Center ); Dr. Nancy LaPelle

Completed

FuRST 2.0 Cognitive Pre-testing - Round 2

Huntington Disease

United States, Canada
Adamas Pharmaceuticals, Inc.

Completed

Safety and Efficacy of ADS-5102 in Multiple Sclerosis Patients With Walking Impairment

Multiple Sclerosis | Walking Impairment

United States, Canada
Adamas Pharmaceuticals, Inc.

Completed

A Safety and Efficacy Study of ADS-5102 in Patients With Multiple Sclerosis and Walking Impairment

Multiple Sclerosis | Walking Impairment

United States, Canada
Hoffmann-La Roche

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7234292 (ISIS 443139) in Huntington's Disease Patients Who Participated in Prior Investigational Studies of RO7234292 (ISIS 443139)

Huntington's Disease

Germany, Canada, United Kingdom
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 443139 in Participants With Early Manifest Huntington's Disease

Huntington's Disease

Canada, United Kingdom, Germany
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Emicizumab in Participants With Mild or Moderate Hemophilia A Without FVIII Inhibitors (HAVEN 6)

Hemophilia A | Mild Hereditary Factor VIII Deficiency Disease Without Inhibitor | Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor

United States, Netherlands, Belgium, France, Germany, South Africa, Spain, Canada, United Kingdom, Poland
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Cognitive/Functional Effects

United States, Canada
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia

Pathological Myopia

Germany, India, Japan, Turkey, Austria, Switzerland, Italy, Lithuania, Hungary, France, Slovakia, United Kingdom, Korea, Republic of, Portugal, Hong Kong, Canada, Singapore, Spain, Latvia, Poland
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Metastatic Cancer | Radiation Toxicity | Cognitive/Functional Effects

United States, Canada
IGC Pharma LLC

Recruiting

IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's (IGC-AD1-P2)

Aggression | Depression | Anxiety | Alzheimer Disease | Memory Impairment | Agitated; State, Acute Reaction to Stress | Agitation,Psychomotor | Care Giving Burden | NPS | Aggressive Outburst

United States, Canada, Puerto Rico
Novartis Pharmaceuticals

Completed

A Dose Range Finding Study With Open-Label Extension to Evaluate the Safety of Oral LMI070/Branaplam in Early Manifest Huntington's Disease (VIBRANT-HD)

Early Manifest Huntington Disease

Canada, Germany, France, Spain, Hungary
CHDI Foundation, Inc.
Medpace, Inc.

Active, not recruiting

Natural History Study in Huntington Disease Gene Expansion Carriers (HDGECs) - SHIELD HD (SHIELD HD)

Huntington Disease

United States, Canada, France, Germany, United Kingdom
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
Eli Lilly and Company
Alzheimer's Therapeutic Research Institute

Completed

Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss (A4)

Cognition Disorders

United States, Canada, Australia, Japan
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Neurotoxicity | Cognitive/Functional Effects

United States, Canada
Merit Cudkowicz
FDA Office of Orphan Products Development

Completed

Pilot Study of Minocycline in Huntington's Disease

Huntington Disease

United States, Canada
Axsome Therapeutics, Inc.

Completed

Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study (SHARP)

Obstructive Sleep Apnea | Excessive Daytime Sleepiness | Impaired Cognitive Function

Spain, United States, Canada, Netherlands, Italy, United Kingdom
Gilead Sciences

Completed

Fanconi Syndrome Due to ARVs in HIV-Infected Persons

HIV Infections | Renal Impairment | Fanconi Syndrome | Kidney Disease

Canada, United States
Hoffmann-La Roche

Terminated

A Study of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Participants With Previously Untreated Advanced BRAFv600 Wild-Type Melanoma

Advanced BRAFV600 Wild-type Melanoma

United States, Korea, Republic of, Australia, Belgium, France, Russian Federation, Italy, Netherlands, Spain, United Kingdom, Brazil, Poland, Germany, Greece, Hungary
Novartis Pharmaceuticals

Completed

Ranibizumab Intravitreal Injections in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRYSTAL)

Central Retinal Vein Occlusion | Macular Edema

Greece, Hungary, Turkey, Australia, Austria, Netherlands, United Kingdom, Italy, Spain, Ireland, Portugal, Slovakia, Canada, Switzerland, Czech Republic, Poland, Denmark, Sweden

Clinical Trials on Mild Cognitive Impairment in Canada

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