Clinical Trials on Mitochondrial DNA Depletion in Netherlands

Total 415 results

Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
Khondrion BV
Radboud University Medical Center

Completed

The KHENERGY Study (KHENERGY)

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS | Mitochondrial Encephalomyopathies | MIDD

Netherlands
Maastricht University

Recruiting

Effect and Safety MABs Administration m.3243A>G Mutation Carriers

Mitochondrial Myopathies

Netherlands
Maastricht University

Recruiting

mtDNA Mutation Load Analysis in Mesoangioblasts (MABS05)

Mitochondrial Myopathies

Netherlands
Maastricht University

Completed

MABs Therapy m.3243A>G Mutation Carriers (MABS01)

Mitochondrial Myopathies

Netherlands
Maastricht University

Terminated

NAD Supplementation Study (NADS)

Aging | Mitochondrial Function

Netherlands
Khondrion BV
Julius Clinical; ProPharma Group; Europees Fonds voor Regionale Ontwikkeling... and other collaborators

Recruiting

The KHENERGYC Study

Mitochondrial Diseases | MELAS | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Subacute Necrotizing Encephalomyelopathy

Netherlands
Maastricht University
Wageningen University and Research; Top Institute Food and Nutrition; Netherlands...

Terminated

The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans

Cognitive Function | Ageing | Physical Function | Mitochondrial Function

Netherlands
Khondrion BV
Julius Clinical

Completed

The KHENERGYZE Study

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS Syndrome | Mitochondrial Encephalomyopathies | MIDD

Netherlands, Denmark, Germany, United Kingdom
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
Maastricht University Medical Center
Unilever R&D

Completed

Hepatic Glycogen and Fat Oxidation

Fasting | Fatty Liver, Nonalcoholic | Glycogen Depletion | Meal Time

Netherlands
Reneo Pharma Ltd

Terminated

An Open Label, Long Term Safety Study of REN001 in Primary Mitochondrial Myopathy Patients (Stride Ahead)

Primary Mitochondrial Myopathy

Spain, Australia, Belgium, Denmark, Canada, United Kingdom, France, Germany, Hungary, Italy, Netherlands, New Zealand
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...
Leiden University Medical Center

Completed

Insufficient Oxygenation in Septic Patients (INOX-SEPSIS)

Sepsis | Fluid Therapy | Critical Care | Oxygen | Mitochondria

Netherlands
Maastricht University Medical Center
Ministry of Education, Culture and Science

Unknown

Human Brown Adipose Tissue and Mitochondrial Respiration

Obesity | Aging | Mitochondrial Metabolism Disorders | Adipose Tissue, Brown

Netherlands
Reneo Pharma Ltd

Completed

An Efficacy and Safety Study of 24 Week Treatment With Mavodelpar (REN001) in Primary Mitochondrial Myopathy Patients (STRIDE)

Primary Mitochondrial Myopathy

United States, Spain, Australia, France, United Kingdom, New Zealand, Denmark, Norway, Czechia, Belgium, Canada, Germany, Hungary, Italy, Netherlands
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...
Leiden University Medical Center

Completed

Mitochondrial Oxygen Measurement Variability in Critically Ill Patients (INOX Variability Study)

Healthy | Mitochondrial Oxygenation Measurement | Measurement Error

Netherlands
UMC Utrecht
Children's Hospital of Philadelphia; Netherlands Brain Foundation

Unknown

Genetics and Psychopathology in the 22q11 Deletion Syndrome

Chromosome 22q11.2 Deletion Syndrome

United States, Netherlands
Radboud University Medical Center
Stichting Stofwisselkracht

Recruiting

MItochondrial Diabetes LOw Carb- Diet Study (MIDLOC)

Mitochondrial Diseases | Diabetes-Deafness Syndrome Maternally Transmitted

Netherlands
Rick Hulskes
Photonics Healthcare B.V., Utrecht, The Netherlands

Completed

Anaesthetic Management Guided by COMET Measurements (AIMED COMET)

Surgical Site Infection | Mitochondrial Oxygenation Measurement

Netherlands
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...
Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Terminated

Insufficient Cellular Oxygen in ICU Patients With Anaemia (INOX ICU-2)

Anemia | Critical Care | Erythrocyte Transfusion | Oxygen | Mitochondria

Netherlands
UMC Utrecht
Eindhoven University of Technology

Recruiting

Early Scoliotic Changes in Children at Increased Risk for Scoliosis Development (EARLYBIRD)

22q11.2 Deletion Syndrome | Adolescent Idiopathic Scoliosis

Netherlands
Erasmus Medical Center
University Medical Center Groningen; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Potassium Supplementation in CKD (K+ in CKD)

Hypertension | Renal Insufficiency, Chronic | Hyperkalemia | Potassium Depletion

Netherlands
University Medical Center Groningen
UMC Utrecht; University of Oxford; Academisch Medisch Centrum - Universiteit... and other collaborators

Completed

Acute Nutritional Ketosis in VLCAD Deficiency

VLCAD Deficiency | Fatty Acid Oxidation Defects

Netherlands
Maastricht University Medical Center
CyTuVax

Completed

Safety and Immunogenicity of HBAI20 Hepatitis B Vaccine in Naive Adults and Non-responders

Hepatitis B

Netherlands
Foundation for Liver Research

Completed

48 Weeks Combination Therapy for Patients With HBeAg-negative Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B

Netherlands
Erasmus Medical Center
Stichting Nuts Ohra

Completed

Hepatitis B Vaccination in HIV-infected Persons

HIV Infections | Hepatitis B

Netherlands
Enyo Pharma
PRA Health Sciences

Completed

EYP001a Food Effect Study in Subjects With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Netherlands
Foundation for Liver Research

Completed

KRN7000 in Chronic Hepatitis B

Hepatitis B, Chronic

Netherlands
Public Health Service of Amsterdam
UMC Utrecht

Unknown

Cohort of Hepatitis B Research of Amsterdam (COBRA)

Hepatitis B

Netherlands
Maastricht University Medical Center
CyTuVax

Completed

Hepatitis B Vaccine for Non-responders

Hepatitis B

Belgium, Netherlands
Foundation for Liver Research

Completed

PEG-IFN in HBV Patients With Incomplete Response to NA (PADD)

Chronic Hepatitis B

Netherlands
Foundation for Liver Research

Completed

Entecavir for Chronic Hepatitis B

Entecavir for Chronic Hepatitis B Patients

Netherlands
Erasmus Medical Center
ISA Pharmaceuticals B.V.

Recruiting

Evaluation of the Novel Therapeutic Hepatitis B Virus Synthetic Long Peptide Vaccination ISA104 (HEB-PEP)

Chronic Hepatitis b

Netherlands
University Medical Center Groningen

Unknown

(Val)Ganciclovir TDM in Transplant Recipients

Cytomegalovirus Infections

Netherlands
Foundation for Liver Research

Completed

Genetic Study of Peginterferon Treatment in Hepatitis B Patients: The GIANT-B Study (GIANT-B)

Chronic Hepatitis B

Netherlands
International Antiviral Therapy Evaluation Center
Gilead Sciences

Completed

Virological and Clinical Anti-Hepatitis B Virus (HBV) Efficacy of Tenofovir and Emtricitabine in Patients With HIV/HBV co-Infection

HIV Infections | Hepatitis B

Netherlands
Radboud University Medical Center
GlaxoSmithKline

Completed

Age Differences in Influenza and Herpes Zoster Vaccine Responses (INFLUENZA-SHINGRIX)

Influenza | Herpes Zoster

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Hepatitis B Surface Antigen(HBsAg) Loss in Chronic Hepatitis B Patients With Low Viral Load (LVL)

Chronic Hepatitis B

Netherlands
Foundation for Liver Research

Completed

Lowering Viral Load With Nucleos(T)Ide Analogues Prior to Peginterferon Treatment to Ncrease Sustained Response in CHB (PEGON)

Chronic Hepatitis B

Netherlands, China
Santhera Pharmaceuticals

Completed

Patient Reported Outcomes in Friedreich's Ataxia Patients After Withdrawal From Treatment With Idebenone (PROTI) (PROTI)

Friedreich's Ataxia

Netherlands, Austria, Germany, United Kingdom
Erasmus Medical Center

Recruiting

Relationship Between MAFLD and Liver Fibrosis Progression in Patients With Chronic Hepatitis B: a Multicenter Retrospective Cohort Study (MAFLD-HBV 1)

Hepatitis B, Chronic

Netherlands
Public Health Service of Amsterdam

Recruiting

Clinical, Virological, Immunological, Psychosocial and Epidemiological Consequences of Human Monkeypox Virus (ProMPX) (ProMPX)

Monkeypox | Monkey Pox

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

From Fungus to Virus, Investigating the Safety and Efficacy of Terbinafine in Chronic Hepatitis B Patients (HepBTer)

Chronic Hepatitis b

Netherlands
University Medical Center Nijmegen
Dutch Kidney Foundation

Completed

Genital HPV Infections Before and After Renal Transplantation

Human Papillomavirus Infections

Netherlands
Prothya Biosolutions

Completed

Intravenous Immunoglobulin (IVIg) for Parvovirus B19(PVB19) Mediated Cardiomyopathy

Myocardial Diseases | Parvovirus B19, Human

Netherlands
Maruho Co., Ltd.

Completed

A Phase 2 Efficacy Study of CLS003 ICVT in Subjects With Cutaneous Warts.

Cutaneous Warts

Netherlands
Santhera Pharmaceuticals

Completed

Long-Term Safety and Tolerability of Idebenone in Friedreich's Ataxia Patients (MICONOS Extension)

Freidreich's Ataxia

Germany, Netherlands, France, Austria, Belgium
Maruho Co., Ltd.

Completed

First-in-Human Study of CLS003 ICVT in Subjects With Cutaneous Warts

Cutaneous Warts

Netherlands
Santhera Pharmaceuticals

Completed

A Study of Efficacy, Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia (FRDA) Patients (MICONOS)

Friedreich's Ataxia

Netherlands, Austria, United Kingdom, Belgium, France, Germany
dr. Laura C. G. de Graaff-Herder

Recruiting

GROWing Up With Rare GENEtic Syndromes (GROW UR GENES)

Disorders of Sex Development | Congenital Adrenal Hyperplasia | Tuberous Sclerosis | Kallmann Syndrome | Prader-Willi Syndrome | Neurofibromatosis | Rett Syndrome | 22q11 Deletion Syndrome | Turner Syndrome | Noonan Syndrome | Allan-Herndon-Dudley Syndrome | Saethre-Chotzen Syndrome | Congenital Hypopituitarism | Cornelia... and other conditions

Netherlands

Clinical Trials on Mitochondrial DNA Depletion in Netherlands

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uganda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations