Clinical Trials on Mitral Valve Stenosis

Total 22905 results

Nantes University Hospital

Completed

Burden Comorbidities and Transcatheter Aortic Valve Implantation (TAVIQUAL)

Symptomatic Severe Aortic Valve Stenosis in Older Patients

France
Shanghai MicroPort Medical (Group) Co., Ltd.

Unknown

Safety and Efficacy Study of MicroPort's Transcatheter Aortic Valve and Delivery System for TAVI

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Calcification

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

IcoSApent ethyL to Slow Down Aortic VAlve Stenosis proGrEssion (SALVAGE)

Aortic Valve Stenosis

Netherlands
Assistance Publique - Hôpitaux de Paris
Action Research Group

Not yet recruiting

Antagonization of Heparin With Protamine Sulfate After TAVI (ATLANTIS-Prota)

Aortic Valve Stenosis | Heart Valve Diseases
Shanghai MicroPort CardioFlow Medtech Co., Ltd.

Recruiting

VitaFlow™ Transcatheter Aortic Valve System Post-market Study-The LAUNCH Study

Aortic Valve Stenosis

China
Edwards Lifesciences

Active, not recruiting

The SAPIEN 3 Ultra System in Intermediate Risk Patients With Symptomatic, Severe Aortic Stenosis

Aortic Valve Stenosis

Canada, United Kingdom
Rennes University Hospital

Terminated

Randomized Study for the Optimal Treatment of Symptomatic Patients With Low Gradient Severe Aortic Valve Stenosis and Preserved Left Ventricular Ejection Fraction (ROTAS)

Aortic Valve Stenosis

France, Belgium
LianBio LLC

Completed

Study Evaluating the Pharmacokinetics of Mavacamten in Healthy Adult Chinese Subjects

Hypertrophic Cardiomyopathy

China
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Registry to Evaluate the Impact of a Valve Coordinator on Aortic Stenosis / TAVI Outcome - (German Pilot) (Coordinate)

Aortic Valve Stenosis

Germany
Nicolaus Copernicus University

Completed

Aortic Valve replAcement in eLective Patients From aOrtic Valve multiceNter Registry (AVALON)

Aortic Valve Stenosis
University of Oxford
British Heart Foundation

Active, not recruiting

Oxford - Fibrates in Aortic Stenosis (OxFAST)

Aortic Valve Stenosis

United Kingdom
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM (VANISH)

Hypertrophic Cardiomyopathy

United States, Canada
Edwards Lifesciences

Completed

PREVAIL-20J - Transfemoral Placement of 20mm Aortic Balloon Expandable Transcatheter Valve Trial (PREVAIL-20J)

Aortic Valve Stenosis

Japan
Edwards Lifesciences

Completed

PREVAIL-J - Transfemoral & Transapical Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Japan)

Aortic Valve Stenosis

Japan
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Study to Improve Outcomes in Aortic Stenosis

Aortic Valve Stenosis

France, Germany
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Small Aortic Annuli and Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
National Heart, Lung, and Blood Institute (NHLBI)
Medstar Washington Hospital Center

Withdrawn

Use of Cardiac-MRI to Predict Results for People With Severe Aortic Stenosis

Aortic Valve Stenosis
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
Assiut University

Unknown

Outcomes of Transcatheter Aortic Valve Implantation in Management of Severe Symptomatic Aortic Stenosis (TAVI)

Aortic Valve Stenosis
Maastricht University Medical Center

Completed

Biological Variation of Cardiac Biomarkers in Aortic Valve Stenosis

Aortic Valve Stenosis

Netherlands
Baylor Research Institute

Completed

Improving Echo Measurements in the Diagnosis of Aortic Stenosis

Aortic Valve Stenosis

United States
Aarhus University Hospital Skejby
Odense University Hospital; Danish Heart Foundation

Terminated

Transapical Transcatheter Treatment Versus Conventional Surgery in Patients With Native Aortic Valve Stenosis

Aortic Valve Stenosis

Denmark
Seoul National University Hospital

Unknown

PCSK9 Inhibitors in the Progression of Aortic Stenosis

Aortic Valve Stenosis

Korea, Republic of
Direct Flow Medical, Inc.

Unknown

Percutaneous Aortic Valve 18F System for the Treatment of Patients With Severe Aortic Stenosis

Aortic Valve Stenosis

Germany, United Kingdom, France, Italy, Luxembourg
Sunnybrook Health Sciences Centre

Completed

Pilot Study of Cognitive and Functional Outcomes Following TAVI

Aortic Stenosis

Canada
Spectranetics Corporation

Completed

Valvuloplasty Scoring Balloon Catheter First-in-Man Study

Aortic Valve Stenosis

Canada
InCor Heart Institute

Completed

Microparticles in Severe Aortic Stenosis

Aortic Valve Stenosis

Brazil
CHU de Reims

Recruiting

Cardiac Amyloidosis Prevalence and Outcome in Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Implantation (CAMPOS-TAVI)

Aortic Stenosis

France
University of Leicester

Completed

Role of Elastin Metabolites in Aortic Remodelling in AS (ELASTIC-AS)

Aortic Stenosis

United Kingdom
University Hospital, Montpellier

Completed

Post TAVI Coronary REVASCularisation Guided by Myocardial Perfusion Imaging: a Prospective Open Label Pilot Study: The REVASC-TAVI Study (REVASC-TAVI)

Stable Coronary Disease | Severe and Symptomatic Aortic Stenosis

France
Heinrich-Heine University, Duesseldorf
German Research Foundation; University Bonn; University Cologne; Collaborative...

Not yet recruiting

Biomarkers and Mechanisms of Disease Progression and Outcome of Aortic Stenosis in Humans

Disease Progression | Aortic Stenosis | Genetics | Pathogenesis | Aortic Valve Calcification | Imaging

Germany
Synecor, LLC

Unknown

The Conveyor Study

Heart Failure | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Disease
UMC Utrecht
Leiden University Medical Center; The Interuniversity Cardiology Institute... and other collaborators

Terminated

The Dutch Asymptomatic Mitral Regurgitation Trial (Dutch AMR)

Mitral Valve Insufficiency | Diseases of Mitral Valve | Heart; Disease, Mitral(Valve)

Netherlands
GCS Ramsay Santé pour l'Enseignement et la Recherche

Recruiting

Predictive Value of Pre-TAVI Infrahissian Conduction Time in the Occurrence of Complete Atrioventricular Block (TAVHIS)

Aortic Stenosis, Severe

France
University of Aarhus
Aarhus University Hospital

Recruiting

Effect of Dapagliflozin on Myocardial and Renal Function Following Aortic Valve Stenosis Intervention (DAPAS)

Aortic Stenosis | Left Ventricle Hypertrophied

Denmark
Friedrich-Alexander-Universität Erlangen-Nürnberg
University of Erlangen-Nürnberg Medical School

Recruiting

Detection of Aortic Stenosis With Smartphone Auscultation Using Machine Learning (HEARTBEAT-Pilot)

Aortic Valve Stenosis

Germany
Tempus AI
Medtronic

Not yet recruiting

Addressing Undertreatment and Health Equity in Aortic Stenosis Using an Integrated EHR Platform (ALERT)

Aortic Valve Stenosis
Venus MedTech (HangZhou) Inc.

Not yet recruiting

Venus-Vitae Pivotal Study Smart-Align Study

Aortic Valve Stenosis
McGill University Health Centre/Research Institute...

Recruiting

Translational-Omics in Aortic Stenosis (TOmAS) Biobank

Cardiovascular Diseases | Aortic Valve Stenosis

Canada
Valve Medical

Recruiting

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

Israel
Shanghai NewMed Medical Co., Ltd.
West China Hospital; The General Hospital of Northern Theater Command

Recruiting

Prizvalve Pro™ Transcatheter Aortic Valve Replacement Study

Aortic Valve Stenosis

China
Duk-Woo Park, MD
CardioVascular Research Foundation, Korea; Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (ENAVO-TAVR)

Aortic Valve Stenosis

Korea, Republic of
Jessa Hospital

Recruiting

Outcome, Recuperation and Hemodynamics in Aortic Stenosis (PROCARE-AS)

Aortic Valve Stenosis

Belgium
Chengdu Silara Meditech Inc.

Recruiting

To Evaluate Safety and Effectiveness of Transcatheter Aortic Valve System in Patients With Severe Aortic Stenosis

Aortic Valve Stenosis

China
Meril Life Sciences Pvt. Ltd.

Recruiting

LANDMARK Trial: a Randomised Controlled Trial of Myval THV (LANDMARK)

Aortic Valve Stenosis

Sweden, Hungary, France, Belarus, Croatia, Germany, Netherlands, New Zealand, Poland, Portugal, Slovakia, Slovenia, Spain, Italy, Brazil, Estonia, Greece
Laval University
University Hospital, Brest

Recruiting

Multicenter Prospective Study of Low-Flow Low-Gradient Aortic Stenosis (TOPAS Study)

Aortic Valve Stenosis

United States, France, Austria, Belgium, Canada, Germany
IHF GmbH - Institut für Herzinfarktforschung
Yale University; Boston Scientific Group

Active, not recruiting

accuRate Evaluation of Benefit With Optimal Medical Treatment With or Without Transcatheter Valve Repair of PARADOXical Low Flow Low Gradient Aortic Stenosis (REBOOT-PARADOX)

Aortic Valve Stenosis

Germany
Shanghai NewMed Medical Co., Ltd.

Active, not recruiting

PrizValve® Transcatheter Aortic Valve Replacement Study

Aortic Valve Stenosis

China
Optimapharm
Edwards Lifesciences

Active, not recruiting

RHEIA (Randomized researcH in womEn All Comers With Aortic Stenosis) (RHEIA)

Aortic Valve Stenosis | Heart Valve Diseases

United Kingdom, Italy, Germany, France, Austria, Switzerland, Finland, Czechia, Belgium, Netherlands, Cyprus, Ireland
Massachusetts General Hospital
University of Colorado, Denver

Completed

Impact of a Patient Decision Aid for Treatment of Aortic Stenosis

Aortic Valve Stenosis

United States

Clinical Trials on Mitral Valve Stenosis

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CROs in Norway

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