Clinical Trials on Mitral Valve Stenosis

Total 22905 results

Michael Ayers
Bristol-Myers Squibb

Not yet recruiting

Effect of Mavacamten Treatment on Coronary Flow Reserve in oHCM (MavaPET)

Obstructive Hypertrophic Cardiomyopathy

United States
Shandong Suncadia Medicine Co., Ltd.

Completed

Effect of Verapamil Tablets on the Pharmacokinetic of HRS-1893 Tablets in Healthy Subjects

Obstructive Hypertrophic Cardiomyopathy

China
Barts & The London NHS Trust

Active, not recruiting

Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United Kingdom
University of Michigan
Stanford University

Completed

Study of Exercise Training in Hypertrophic Cardiomyopathy (RESET-HCM)

Cardiomyopathy, Hypertrophic

United States
Assistance Publique - Hôpitaux de Paris

Completed

Valvular Aortic Stenosis: Study of Myocardiac Fibrosis by Magnetic Resonance Imagery (RACINE)

Aortic Valve Stenosis

France
Stanford University
University of Michigan

Unknown

Exercise Study Including Patients With Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Role of Heart Stiff and Weak Atrium on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States
Boston Scientific Corporation

Active, not recruiting

A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation

Cardiovascular Diseases | Mitral Regurgitation Functional | Mitral Valve Disease

United States, Australia
Ancora Heart, Inc.

Completed

A Study of Percutaneous Repair of Functional Mitral Regurgitation Using the Ancora Heart, Inc. AccuCinch® Ventricular Repair System - The CINCH-2 Study (CINCH-2)

Mitral Regurgitation | Mitral Valve Regurgitation | Functional Mitral Regurgitation

Austria, Lithuania, Germany
Edwards Lifesciences

Recruiting

Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial (CLASP IID/IIF)

Mitral Regurgitation | Mitral Insufficiency | Functional Mitral Regurgitation | Degenerative Mitral Valve Disease

United States, Canada, Switzerland, Germany
Henry Ford Health System
Medtronic

Completed

Conduction Disease After Transcatheter Aortic Valve Replacement

Aortic Stenosis | Heart Block | Aortic Insufficiency

United States
Hospital Universitari Son Dureta
Laboratorios BIOMED SA

Unknown

Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications (CALCIFICA)

Aortic Stenosis | Heart Valve Disease

Spain
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Evaluation of Mitral Valve Insufficiency Under General Anesthesia (MITIGATE)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Netherlands
Medtronic Cardiovascular

Recruiting

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. (APOLLO)

Mitral Valve Regurgitation

United States, Canada, Denmark
Michele De Bonis

Completed

Durability at 20 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation

Mitral Valve Disease

Italy
Heart Repair Technologies, Inc.
Na Homolce Hospital

Terminated

Observational Study of the Heart Repair Technologies Mitral Bridge in Treating Mitral Valve Regurgitation (HRT)

Mitral Regurgitation

Czechia
Edwards Lifesciences

Active, not recruiting

Edwards Cardioband European Post-Market Study, MiBAND (MiBAND)

Mitral Regurgitation | Mitral Insufficiency | Mitral Repair | Mitral Valve | Annuloplasty | Edwards Cardioband

Switzerland, Germany, Italy
Cardiovalve Ltd.
Meditrial Europe Ltd.; Meditrial SrL

Recruiting

AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System (AHEAD)

Mitral Regurgitation | Mitral Valve Disease

Germany, Italy, Greece
IRCCS Policlinico S. Donato

Active, not recruiting

GIse Registry Of Transcatheter Treatment of Mitral Valve regurgitaTiOn (GIOTTO) (GIOTTO)

Mitral Regurgitation

Italy
Abbott Medical Devices
Abbott

Completed

MitraClip NT System Post-marketing Surveillance Study - Japan (MitraClip NT)

Mitral Regurgitation | Mitral Valve Regurgitation

Japan
Edwards Lifesciences

Terminated

REPAIR - transcatheteR rEPair of mitrAl Insufficiency With caRdioband System (REPAIR)

Heart Diseases | Cardiovascular Diseases | Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Cardiac Valve Annuloplasty | Mitral Valve Annuloplasty

Germany, Italy, France
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States, Australia, Canada, France, Germany, Ireland, Italy, Spain, United Kingdom
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy (MEMENTO)

Cardiomyopathy, Hypertrophic

United States, Argentina, Australia, Belgium, Canada, Czechia, Hungary, Poland, Switzerland, France, Austria, Finland, Germany, Greece, Italy, Spain, United Kingdom
China National Center for Cardiovascular Diseases

Not yet recruiting

The Safety and Effectiveness of Transcatheter Aortic Valve Raplacemet in Intermediate Risk Patients With Bicuspid Aortic Stenosis

Aortic Valve Disease
Bristol-Myers Squibb

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, and Tolerability of MYK-224 in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy (MERCUTIO)

Cardiomyopathy, Hypertrophic

Italy, United States, Poland, Spain
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); Brigham and Women's Hospital

Active, not recruiting

The Impact of Exercise-Induced Cardiac Remodeling on Myocardial Efficiency

Cardiomyopathy, Hypertrophic

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States, Germany, United Kingdom, Spain, Korea, Republic of, Greece
University of East Anglia
Norfolk and Norwich University Hospitals NHS Foundation Trust; British Medical...

Unknown

Nitrite in Hypertrophic Cardiomyopathy (HCM) Study

Cardiomyopathy, Hypertrophic

United Kingdom
University Hospital, Strasbourg, France

Unknown

Effects of High Dose Atorvastatin in Patients With Surgical Aortic Stenosis

Aortic Valve Stenosis | Ventricular Hypertrophy

France
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Long-Term Results of DDD Pacing in Obstructive Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States
Bristol-Myers Squibb

Recruiting

Mavacamten Pregnancy Surveillance Program

Pregnancy Related | Hypertrophic Cardiomyopathy | Breastfeeding

United States
China National Center for Cardiovascular Diseases

Recruiting

The Chinese Hypertrophic Cardiomyopathy Study(CHCS) (CHCS)

Cardiomyopathy, Hypertrophic

China
Bristol-Myers Squibb

Active, not recruiting

A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy (ODYSSEY-HCM)

Cardiomyopathy, Hypertrophic

Spain, Austria, Belgium, Brazil, Canada, Denmark, France, Germany, Hungary, Israel, Japan, Netherlands, Norway, Poland, Portugal, United Kingdom, United States, Australia, China, Czechia, India, Italy, Korea, Republic of
Heinrich-Heine University, Duesseldorf

Completed

PASCAL vs. MitralClip for Mitral Valve Transchatheter Edge-to-Edge Repair

Mitral Regurgitation | Functional Mitral Regurgitation | Degenerative Mitral Valve Regurgitation

Germany
Universitaire Ziekenhuizen KU Leuven
University Hospital, Antwerp; AZ Delta

Active, not recruiting

COronary and MICrocirculatory Measurements in Patients With Aortic Valve Stenosis. (COMIC-AS)

Coronary Artery Disease | Aortic Stenosis

Belgium
IRCCS Policlinico S. Donato

Recruiting

OUTcomes Evaluation of Current Therapeutic STrategies for Severe Aortic Valve steNosis anD the agING Population in ITALY (OUTSTANDING)

Aortic Valve Stenosis

Italy
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Validation of the "TASQ" in Patients Undergoing SAVR or TF-TAVI (TASQ)

Aortic Valve Stenosis

Austria, Canada, France, Germany, Italy, Spain, United Kingdom
Linkoeping University

Terminated

Rehabilitation in Aortic Stenosis Patients (RASP)

Aortic Valve Stenosis

Sweden
OCEAN-SHD Study Group

Recruiting

Non-antithrombotic Therapy After Transcatheter Aortic Valve Implantation Trial

Aortic Stenosis | Aspirin | TAVI(Transcatheter Aortic Valve Implantation) | DAPT(Dual Antiplatelet Therapy) | SAPT(Single Antiplatelet Therapy)

Japan
Qilu Hospital of Shandong University

Not yet recruiting

Safety and Efficacy of Emergent TAVI in Patients With Severe AS

Emergencies | Aortic Valve Stenosis | Transcatheter Aortic Valve Implantation
The Cleveland Clinic
National Institutes of Health (NIH)

Completed

The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of Glucose

Hyperglycemia | Aortic Stenosis | Cardiac Surgery | Aortic Valve Replacement

United States
Polares Medical SA
Polares Medical, Inc.

Not yet recruiting

EXPLORE MRace: Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant (EXPLORE MRace)

Mitral Valve Disease

Brazil
P+F Products + Features GmbH
Meditrial USA Inc.

Not yet recruiting

Munich Transcatheter Mitral Valve Safety and Effectiveness (MUSE)

Mitral Regurgitation | Mitral Valve Disease

Brazil, Argentina, Chile
Polares Medical SA

Terminated

Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation (EXPLORE MR)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Switzerland, Germany
Abbott Medical Devices
Abbott

Active, not recruiting

MitraClip EXPAND G4 Study

Mitral Regurgitation | Mitral Valve Regurgitation

United States, Canada, Spain, Israel, Germany, Italy, Japan, France, Netherlands, Saudi Arabia
Duk-Woo Park, MD
CardioVascular Research Foundation, Korea

Completed

Transcatheter Mitral Valvuloplasty Pilot Study (MitraClip)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation

Korea, Republic of
Abbott Medical Devices
Abbott

Completed

The MitraClip® EXPAND Study of the Next Generation of MitraClip® Devices

Mitral Regurgitation | Mitral Valve Regurgitation

Netherlands, United Kingdom, United States, Spain, Israel, Germany, Italy, Switzerland
Edwards (Shanghai) Lifesciences Medical Supplies...

Completed

A Retrospective Study to Collect the Data From the Patients Who Had the Perimount Heart Valve Replacement Surgery in China During 2001 to 2007

Mitral Valve or Aortic Valve Replacement

China
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation

Mitral Regurgitation | Degenerative Mitral Valve Disease

China
Polares Medical SA

Terminated

Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation (EXPLORE DMR)

Degenerative Mitral Valve Disease

United States

Clinical Trials on Mitral Valve Stenosis

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