Clinical Trials on Mosquito-Borne Disease

Total 381762 results

University of Oxford
Mahidol University

Not yet recruiting

A Safety, Immunogenicity and Efficacy Study of PvRII/Matrix-M in Healthy Thai Adults Living in Thailand ( MIST3 ) (MIST3)

Plasmodium Vivax Infection | Malaria Vaccine

Thailand
University of California, Irvine

Active, not recruiting

Adaptive Interventions for Optimizing Malaria Control: A Cluster-Randomized SMART Trial

LLIN, PBO LLIN, IRS, Larviciding

United States, Kenya
University of Oxford
Bill and Melinda Gates Foundation; University Hospitals Bristol and Weston...

Recruiting

A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™

Malaria,Falciparum

United Kingdom
University of Oxford
PATH

Not yet recruiting

Southeast Asia Dose Optimization of Tafenoquine (SEADOT)

Plasmodium Vivax Malaria

Cambodia, Lao People's Democratic Republic, Thailand, Vietnam
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Clinton Health... and other collaborators

Completed

Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Nigeria

Malaria | Febrile Illness

Nigeria
Menzies School of Health Research
Tribhuvan University, Nepal

Active, not recruiting

Short Course Radical Cure of P. Vivax Malaria in Nepal

Malaria | Malaria, Vivax | Malaria,Falciparum

Nepal
University of Oxford

Not yet recruiting

Mass Vaccine and Drug Administration, Bangladesh (MVDA)

Plasmodium Falciparum Malaria

Bangladesh
Shoklo Malaria Research Unit
Mahidol Oxford Tropical Medicine Research Unit

Recruiting

ACT vs CQ With Tafenoquine for P. Vivax Mono-infection (ACTQ)

Malaria | Malaria, Vivax | Plasmodium Vivax Malaria

Thailand
University of Oxford

Completed

Mass Screening and Treatment for Reduction of Falciparum Malaria (MSAT)

Plasmodium Falciparum Malaria

Thailand
Groupe de Recherche Action en Sante
European Vaccine Initiative

Recruiting

Malaria Burden in Pregnant Women and the Incidence of Pregnancy in a Cohort of Nulligravida (EPI-PAM)

Maternal Malaria During Pregnancy - Baby Not Yet Delivered

Burkina Faso
Menzies School of Health Research
Aga Khan University; University of Melbourne; Universitas Sumatera Utara; Ethiopian... and other collaborators

Recruiting

Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and Primaquine (EFFORT)

Vivax Malaria | Malaria, Vivax | Plasmodium Vivax | Malaria Relapse

Cambodia, Ethiopia, Indonesia, Pakistan
Novartis Pharmaceuticals
Wellcome Trust; European and Developing Countries Clinical Trials Partnership...

Recruiting

To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria

Severe Malaria

Burkina Faso, India, Rwanda, Congo, The Democratic Republic of the, Gabon, Nigeria, Côte D'Ivoire, Kenya
Grant Dorsey, M.D, Ph.D.
National Institutes of Health (NIH); Infectious Diseases Research Collaboration...

Active, not recruiting

Optimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda

Malaria

Uganda
Menzies School of Health Research
National Health and Medical Research Council, Australia; Wellcome Trust

Suspended

Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria (ARGISM)

Severe Falciparum Malaria

Indonesia
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Recruiting

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs. (DeTACT-Africa)

Plasmodium Falciparum Malaria (Uncomplicated)

Burkina Faso, Congo, The Democratic Republic of the, Gambia, Guinea, Nigeria, Niger, Rwanda, Tanzania
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Completed

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia) (DeTACT-ASIA)

Plasmodium Falciparum Malaria (Uncomplicated)

Cambodia, Bangladesh
Novartis Pharmaceuticals

Recruiting

Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Patients With Uncomplicated Plasmodium Falciparum Malaria (PLATINUM)

Uncomplicated Plasmodium Falciparum Malaria

Côte D'Ivoire, Kenya, Ghana, Uganda
Centers for Disease Control and Prevention
Ministry of Health, Liberia

Completed

Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia

Malaria | Plasmodium Falciparum | Uncomplicated Malaria

Liberia
Myanmar Health Network Organization
Chulalongkorn University; Ministry of Health and Sports, Myanmar

Completed

Health Education by Buddhist Monks to Promote Malaria Knowledge and Preventive Practices in Rural Myanmar

Malaria | Health Education | Buddhist Monks | Monastery-based | Myanmar | Preventive Practice

Myanmar
National Institute of Allergy and Infectious Diseases...

Completed

A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects.

Zika Virus Infection

United States
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Active, not recruiting

Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV

Malaria

Uganda
Novartis Pharmaceuticals
MMV, EDCTP, WANECAM

Recruiting

Efficacy, Safety and Tolerability of KLU156 in Adults and Children ≥ 5 kg Body Weight With Uncomplicated P. Falciparum Malaria (KALUMA)

Uncomplicated Plasmodium Falciparum Malaria

Congo, The Democratic Republic of the
Malaria Consortium, Ethiopia
Columbia University; Addis Ababa University; Coalition Against Malaria in Ethiopia

Completed

Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia

Malaria | Mosquito Repellent | Long Lasting Insecticidal Nets

Ethiopia
Valneva Austria GmbH

Recruiting

Phase 1 Trial to Assess the Safety and Immunogenicity of an Inactivated, Adjuvanted Whole Zika Virus Vaccine Candidate (VLA1601) in Healthy Adults

Zika | Zika Virus Infection

United States
Butantan Institute
Valneva Austria GmbH

Completed

A Multicenter Study to Evaluate Safety and Immunogenicity of a Live-attenuated Chikungunya Vaccine in Adolescents

Chikungunya

Brazil
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-64281802 for the Prevention of Dengue Infection

Dengue

Mexico, Malaysia, Brazil, Colombia, Puerto Rico, Panama, Peru, Philippines, Thailand
State University of New York - Upstate Medical...
Walter Reed Army Institute of Research (WRAIR); U.S. Army Medical Research...

Completed

Dengue 3 Human Infection Model (DENV-3)

Dengue

United States
State University of New York - Upstate Medical...
U.S. Army Medical Research and Development Command; Janssen Pharmaceutica N...

Completed

Expansion of a Dengue-1 Live Virus Human Challenge

Dengue

United States
Takeda

Withdrawn

A Study of Purified Inactivated Zika Virus Vaccine (PIZV) in Healthy Adults

Healthy Volunteers

United States
Emergent BioSolutions

Completed

Study in Healthy Volunteers Evaluating Safety and Pharmacokinetics of Zika Virus Immune Globulin (ZIKV-IG)

Zika Virus Infection | Zika Virus Disease

Canada
Butantan Institute
Merck Sharp & Dohme LLC

Active, not recruiting

Clinical Bridging Study Between V181 (Dengue Quadrivalent Vaccine rDENVΔ30 [Live, Attenuated]) to Butantan Dengue Vaccine (Butantan-DV) in Healthy Adults 18 to 50 Years of Age in Brazil (V181-002)

Dengue

Brazil
Instituto Mexicano del Seguro Social
Instituto Nacional de Salud Publica, Mexico; Centro de Investigación en Matemáticas...

Completed

Identification of Risk Determinants of Dengue Transmission Through Landscape Analysis (IRDDENGUELA)

Dengue

Mexico
University of Oxford
Mahidol University

Recruiting

Vivax Malaria Human Infection Studies in Thailand (MIST1)

Plasmodium Vivax Infection

Thailand
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University; University of Maryland; University of California, San... and other collaborators

Recruiting

Platelet-Directed Whole Blood Transfusion Strategy for Malaria (PLATFORM)

Thrombocytopenia | Severe Malaria

United States, Zambia
University of Maryland, Baltimore
Medical Technology Enterprise Consortium (MTEC)

Completed

Dengue 4 Human Infection Model (Dengue CVD 11000; DHIM-4)

Dengue

United States
Leiden University Medical Center

Not yet recruiting

Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge)

Malaria,Falciparum
Bavarian Nordic

Recruiting

Long-term Follow-up Study to Evaluate Safety and Immunogenicity of PXVX0317 Single or Booster Vaccination

Chikungunya Virus Infection

United States
George Washington University
Naval Medical Research Center; Clinica de la Costa; Global Disease Research

Recruiting

Zanamivir Treatment of Vascular Permeability in Dengue (ZAP-DENGUE) (ZAP-DENGUE)

Dengue Fever

Colombia
National Institute of Allergy and Infectious Diseases...

Recruiting

A Cluster-randomized Trial to EValuate the Efficacy of Wolbachia-InfecTed Aedes Aegypti Mosquitoes in Reducing the Incidence of Arboviral Infection in Brazil (EVITA Dengue)

Dengue Fever

Brazil
Takeda

Completed

Immunogenicity and Safety of Tetravalent Dengue Vaccine Candidate (TDV) in Flavivirus-Naïve and Dengue-Immune Adults

Dengue Fever

United States
Takeda

Completed

Safety and Immunogenicity of Takeda's Tetravalent Dengue Vaccine (TDV) in Healthy Children

Healthy Volunteers

Philippines, Panama
Takeda

Not yet recruiting

A Study to Monitor the Adverse Events of QDENGA Vaccine in Participants in Malaysia (PRIME-Q)

Dengue Fever

Malaysia
Valneva Austria GmbH

Recruiting

A Phase 2 Clinical Study of VLA1553 in Healthy Children Aged 1 to 11 Years

Chikungunya Virus Infection

Dominican Republic, Honduras
Takeda

Recruiting

A Study of Dengue Vaccine in Healthy Children, Teenagers and Adults in India

Healthy Volunteers

India
National Institute of Allergy and Infectious Diseases...

Completed

Investigating Vector-Borne Determinants of Aedes Transmitted Arboviral Infections in Cambodia: An Observational Longitudinal Cohort Study in Children

Dengue Fever

Cambodia
Novartis Pharmaceuticals

Active, not recruiting

A Study to Assess the Efficacy, Safety and Pharmacokinetics of EYU688 in Patients With Dengue Fever

Dengue

Singapore, Malaysia, India
GlaxoSmithKline

Terminated

This Study Will Describe the Burden of DENgue Fever Virus (DENV) Illness Among Household Members Aged 6 Months to 50 Years of Selected Communities in Latin America and Southeast Asia

Dengue | Dengue Vaccines

Philippines, Mexico
Menzies School of Health Research
University of Medicine 2, Yangon

Completed

Empirical ANtibiotic THErapy in Adults Hospitalised With Malaria (ANTHEM)

Sepsis | Bacteremia | Malaria

Myanmar
Takeda

Active, not recruiting

Long-Term Safety and Antibody Persistence of TDV and the Impact of a Booster Dose

Dengue Fever

Mexico, United States
Menzies School of Health Research
International Centre for Diarrhoeal Disease Research, Bangladesh

Completed

A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh

Malaria

Clinical Trials on Mosquito-Borne Disease

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Medical Conditions

Drug Interventions

CROs by country

CROs in Estonia

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Rare Diseases

Drug Interventions

Dietary Supplements

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