Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia

July 9, 2010 updated by: Malaria Consortium, Ethiopia

Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Southern Ethiopia: a Cluster-randomized Controlled Trial

The combined use of a mosquito repellent and long lasting insecticidal nets (LLINs) by household members would result in a 40% reduction in malaria prevalence compared with households that only use LLINs.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

It has been recognized that the use of malaria preventive measures in combination with LLINs could improve the effectiveness of nets in preventing the disease. This study examined the effect of a combined use of mosquito repellent (i.e., Buzz Off) and LLINs on malaria prevalence in an area of unstable and seasonal malaria transmission.

Study Type

Interventional

Enrollment (Actual)

6082

Phase

  • Phase 4

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Ethiopia
    • Snnpr
      • Awassa, Snnpr, Ethiopia
        • SNNPR, Ethiopia

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • All volunteer household members

Exclusion Criteria:

  • Infants less than two months
  • Not in the study area

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Mosquito repellent and LLINs group vs. LLINs group only
This study is based on two population groups: 1) a group of households that use LLINs alone (control) and 2) a group of households that use both mosquito repellent and LLINs (repellent group).
Other: Mosquito repellent
Mosquito repellent (Buzz Off jelly) every evening applied to face, neck, hands and legs

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Malaria parasite (P. falciparum and/or P. vivax)through microscopic detection
The objective of the study is to investigate the impact of a combined use of mosquito repellent and LLINs in reducing malaria. The primary outcome of the study is detection of malaria parasites (P. falciparum and/or P. vivax) through examination of microscopic blood slides collected from finger-pricks.

Secondary Outcome Measures

Outcome Measure
Measure Description
Household ownership and utilization of LLINs
Owneship and utilization of LLINs by household members during the night before the baseline survey

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Malaria Consortium, Ethiopia

Collaborators

Columbia University
Addis Ababa University
Coalition Against Malaria in Ethiopia

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2008

Primary Completion (Actual)

December 1, 2008

Study Completion (Actual)

January 1, 2009

Study Registration Dates

First Submitted

July 8, 2010

First Submitted That Met QC Criteria

July 9, 2010

First Posted (Estimate)

July 12, 2010

Study Record Updates

Last Update Posted (Estimate)

July 12, 2010

Last Update Submitted That Met QC Criteria

July 9, 2010

Last Verified

July 1, 2010

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 0001 (Cancer Research Institute)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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