Clinical Trials on Mucopolysaccharidose IV

Total 3086 results

Centre Oscar Lambret

Completed

Sparing of Organs at Risk in High Dose Rate Brachytherapy

Cervical Carcinoma Stage IB to IV

France
Masonic Cancer Center, University of Minnesota

Terminated

Hematopoietic Stem Cell Transplantation (HCT) for Inborn Errors of Metabolism

Sphingolipidoses | Niemann-Pick Disease, Type C | Krabbe Disease | Sly Syndrome | Fucosidosis | Aspartylglucosaminuria | Alpha Mannosidosis | Hurler's Syndrome | Maroteaux-Lamy Syndrome | Wolman's Disease | Niemann-Pick Disease Type B

United States
Wuerzburg University Hospital
Charite University, Berlin, Germany; Goethe University; RWTH Aachen University; Technical University of Munich and other collaborators

Recruiting

Artificial Intelligence-augmented Perioperative Clinical Decision Support (KIPeriOP)

Surgery | ASA Class III/IV Patients | Clinical Decision Support Systems

Germany
University Hospital, Geneva
European Society for Blood and Marrow Transplantation

Recruiting

Polymorphisms and Busulfan Pharmacokinetic Study

Children Who Receive a Stem Cell Transplantation With Busulfan IV

Canada, France, Switzerland
University of Alberta

Completed

Virtual Reality-based Distraction to Reduce Distress in the Pediatric Emergency Department

Children Requiring IV Placement

Canada
University of Alberta

Completed

Robot-Based Distraction to Reduce Pain and Distress in the Pediatric Emergency Department

Children Requiring IV Placement

Canada
The University of Hong Kong

Unknown

Evaluation of a New Airway Device - the YO2(R) Catheter in Patients Under Sedation

Patients Undergoing Anesthesiologist-administered iv Sedation During Diagnostic/ Therapeutic Procedures

China
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Maroteaux-Lamy Disease (BioMaroteaux) (BioMaroteaux)

Lung Diseases | Eye Abnormalities | Lysosomal Storage Disease | Macroglossia | Obstructive Sleep Apnoea

Germany, India, Sri Lanka, Egypt
Bellicum Pharmaceuticals

No longer available

BPX-501 T Cells Infused Post Stem Cell Transplant in Pediatrics With Non-Malignant Disorders Ineligible for BPU004 Study

Hurler Syndrome | Inborn Errors of Metabolism | Metachromatic Leukodystrophy | Inherited Metabolic Disorder | Lysosomal Storage Disorder

United States
Duke University

Completed

Partner-Assisted Emotional Disclosure for GI Cancer

Cancer of the GI System-stages II III and IV

United States
West China Hospital

Recruiting

Combination of Sintilimab and Stereotactic Body Radiotherapy in Advanced Metastatic HCC

Immunotherapy | SBRT | Stage IV HCC

China
Universitaire Ziekenhuizen KU Leuven

Completed

SecurAcath Versus Statlock for PICC Securement (SecurAstaP)

Patients With Any Condition Who Need a PICC for IV Therapy

Belgium
Duke University

Completed

Use of Electrical Impedence to Measure Lean Body Weight as a Determinant of the Dose of Contrast Media for Abdominal CT

IV Contrast Dosing
The University of Texas Health Science Center,...
ZARS Pharma Inc.

Unknown

In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction? (Synera patch)

Pain on Propofol IV Injection

United States
University of California, San Francisco
Merck Sharp & Dohme LLC

Terminated

Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8

United States
Microbio Co Ltd

Recruiting

Safety and Potential Efficacy of MS-20 In Combination With Pembrolizumab for the Treatment of NSCLC

NSCLC Stage IV

Taiwan
The Netherlands Cancer Institute
Bristol-Myers Squibb

Terminated

Early Response Evaluation in NSCLC Patients Treated With Immunotherapy

NSCLC, Stage IV

Netherlands
Fudan University

Unknown

Pemetrexed and Carboplatin With or Without Anlotinib Hydrochloride for Osimertinib-resistant Non-squamous NSCLC (PCA)

NSCLC Stage IV

China
The University of Texas Health Science Center,...

Completed

Combining Placing a Synera Patch With Propofol/Lidocaine Mixture to Decrease Pain With IV Propofol Injection

Pain on IV Injection of Propofol.

United States
Ohio State University Comprehensive Cancer Center

Completed

2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer

Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IV A Bladder Cancer | Stage IV A Rectal Cancer | Stage IV B Colon Cancer | Stage IV B Rectal Cancer

United States
Campus Bio-Medico University

Recruiting

Breast Stereotactic Radiotherapy to Primary Tumors in Metastatic Patients (BoMB)

Stage IV Breast Cancer

Italy
KangLaiTe USA

Terminated

Safety and Exploratory Efficacy of Kanglaite Injection in Non Small Cell Lung Cancer

Stage IV NSCLC

United States
Guangzhou Institute of Respiratory Disease

Not yet recruiting

Rh-endostatin Combined With Chemotherapy and Pembrolizumab for Advanced NSCLC

Staging IV NSCLC

China
Mylan Pharmaceuticals Inc

Completed

MYL-1402O Compared With Avastin®, in Patients With Stage IV nsNSCLC

NSCLC Stage IV

Turkey, Taiwan, Vietnam, Croatia, India, Russian Federation, Spain, Hungary, Bosnia and Herzegovina, Ukraine, Poland, Romania, Belarus, Bulgaria, Georgia, Italy, Philippines
Instituto do Cancer do Estado de São Paulo

Unknown

Factors Determining the Prognosis in NSCLC Stage IV (LUPROG)

NSCLC Stage IV

Brazil
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer

Gastric Adenocarcinoma | Oligometastasis | Stage IV Esophageal Cancer AJCC v7 | Stage IV Gastric Cancer AJCC v7 | Stage IV Esophageal Adenocarcinoma AJCC v7

United States
Massachusetts General Hospital
Conquer Cancer Foundation

Active, not recruiting

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer (UPLIFT)

Stage IV Non-Small Cell Lung Cancer | Stage IV Bladder Cancer | Stage IV Breast Cancer | Stage IV Melanoma | Immunotherapy | Immune Checkpoint Inhibitors | Stage IV Gastric Cancer | Stage IV Merkel Cell Carcinoma | Stage IV Colorectal Cancer | Stage IV Esophageal Cancer | Advanced Lung Cancer | Stage IV Renal... and other conditions

United States
Holy Cross Hospital, Maryland

Withdrawn

Personalizing Immune Checkpoint Inhibitor Therapy

Lung Cancer Stage IV

United States
Cardiogenesis Corporation, a wholly-owned subsidiary...

Terminated

The PEARL 8.0 Post-Approval Study

Class IV Angina

United States
Stony Brook University
Garnett McKeen Laboratory Inc.

Completed

Dose Evaluation Safety STudy IN Individuals With Astrocytoma Taking PolyMVA (DESSTINI_A)

Glioblastoma Multiform (Grade IV Astrocytoma)

United States
Roswell Park Cancer Institute

Recruiting

Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma

United States
M.D. Anderson Cancer Center

Completed

Radiation Therapy and M7824 in Treating Patients With Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Aromatase Inhibitor Therapy With or Without Fulvestrant for the Treatment of HR Positive Metastatic Breast Cancer With an ERS1 Activating Mutation, the INTERACT Study

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Suspended

Optimizing Treatment of Stage IV Breast Cancer Through Real-Time Disease Monitoring

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

High-Dose Cholecalciferol in Treating Patients Receiving Combination Chemotherapy and Bevacizumab as First-Line Therapy For Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer

United States
Charite University, Berlin, Germany
Klinikum rechts der Isar, TU München, (TUM), Munich, Germany.

Recruiting

Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells (HSP70CTC)

Sarcoma | Prostate Cancer | Pancreatic Cancer Stage IV | Breast Cancer Stage IV | Squamous Cell Carcinoma | Melanoma Stage IV

Germany
National Cancer Institute (NCI)

Completed

Veliparib and Floxuridine in Treating Patients With Metastatic Epithelial Ovarian, Primary Peritoneal Cavity, or Fallopian Tube Cancer

Stage IV Fallopian Tube Cancer AJCC v6 and v7 | Stage IV Ovarian Cancer AJCC v6 and v7 | Stage IV Primary Peritoneal Cancer AJCC v7

United States
National Cancer Institute (NCI)

Terminated

Oblimersen and Gemcitabine in Treating Patients With Advanced Solid Tumor or Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Shanghai Chest Hospital
Bristol-Myers Squibb

Completed

Nivolumab Combined With Anlotinib as Re-challenge Treatment in Advanced NSCLC

NSCLC Stage IV | Checkpoint Inhibitor

China
University of Tartu
Tartu University Hospital; Estonian Science Foundation

Recruiting

Prognostic Hemodynamic and Metabolic Profiles of Late Stage Lower Extremity Arterial Disease (PREDICTOR)

Lower Extremity Arterial Disease (Fontaine Stages IIb-IV)

Estonia
Azienda Ospedaliero Universitaria Maggiore della...

Completed

Parenchymal Sparing Hepatectomy in Post-chemotherapy Liver Atrophy

Colorectal Cancer Stage IV
Fujian Cancer Hospital

Unknown

EGFR Mutation Positive NSCLC Patients With Gefitinib and Thalidomide

Chemotherapy Effect | NSCLC Stage IV

China
National Cancer Institute (NCI)

Terminated

Geldanamycin Analogue in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Fairview University Medical Center

Unknown

Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Mucopolysaccharidosis I | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Metachromatic Leukodystrophy | Pulmonary Complications | Fucosidosis | Globoid Cell Leukodystrophy | Gaucher's Disease | Mannosidosis | I Cell Disease

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Stage III or Stage IV Low-Grade Non-Hodgkin's Lymphoma

Stage III Grade 1 Follicular Lymphoma | Stage III Grade 2 Follicular Lymphoma | Stage III Grade 3 Follicular Lymphoma | Stage III Small Lymphocytic Lymphoma | Stage IV Grade 1 Follicular Lymphoma | Stage IV Grade 2 Follicular Lymphoma | Stage IV Grade 3 Follicular Lymphoma | Stage IV Small Lymphocytic...

United States
Vestre Viken Hospital Trust
Odense University Hospital; Karolinska University Hospital; Oslo University Hospital and other collaborators

Recruiting

Sotorasib in Advanced KRASG12C-mutated Non-small Cell Lung Cancer Patients With Comorbidities (SOLUCOM)

Cancer | Lung Cancer | NSCLC Stage IV | Mutation | NSCLC, Stage III | Lung Cancer Stage IV | Cancer, Lung

Norway
ETOP IBCSG Partners Foundation
AstraZeneca

Active, not recruiting

Osimertinib and Locally Ablative Radiotherapy in Patients With Synchronous Oligo-metastatic EGFR Mutant NSCLC (STEREO) (STEREO)

NSCLC Stage IV | EGFR Gene Mutation

Singapore, Sweden, Korea, Republic of, Spain, Switzerland, Netherlands, Italy, Poland
HyGIeaCare, Inc.

Completed

Microbiome Analysis of Constipated Versus Non-constipation Patients

Rome IV Functional Constipation

United States
HyGIeaCare, Inc.

Withdrawn

HygiRelief Procedure and HygiSample Evaluation for Functional Constipation

Rome IV Functional Constipation
University of California, San Francisco

Completed

Ultrasound Guidance for Intravenous Cannulation in Emergency Department Patients.

Difficult IV Access

United States

Clinical Trials on Mucopolysaccharidose IV

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