Clinical Trials on Mucopolysaccharidosis II

Total 2564 results

Damascus University

Completed

Patient Outcomes Associated With Two Accelerated Method of Retraction of Upper Front Teeth

Class II Division 1 Malocclusion

Syrian Arab Republic
Firstkind Ltd

Completed

Firefly ANKLE Sprain Study

Grade I/II Ankle Sprain

United Kingdom
Massachusetts General Hospital
Brigham and Women's Hospital; Abbott Medical Devices

Completed

Dual-Source Computed Tomography to Improve Prediction of Response to Cardiac Resynchronization Therapy (DIRECT)

Wide QRS Complex | Heart Failure - NYHA II - IV

United States
Visnja Katic
University of Rijeka; Clinical Hospital Center Rijeka

Completed

Predictors Associated With Seeking Orthodontic Treatment, Compliance and Treatment Success (PONCOS)

Malocclusion, Angle Class II

Croatia
Damascus University

Completed

Evaluation of the Levels of Pain and Discomfort Associated With Two Techniques of Corticotomy

Class II Division 1 Malocclusion

Syrian Arab Republic
Jordan University of Science and Technology
University of Edinburgh; University of Sydney

Completed

The Rate of Space Closure With Piezocision-based Corticotomy in Different Facial Types: A Split-mouth Design (RCT)

Class II Div 1 Malocclusion

Jordan
National Cancer Institute (NCI)

Completed

Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma

Glioma | Glioblastoma Multiforme | Giant Cell Glioblastoma | Oligodendrogliomas | Astrocytoma, Grades II, III and IV

United States
Oregon State University
Sanofi

Completed

Empowering Patients to Better Manage Diabetes Through Self-Care

Type I or Type II Diabetes (Excludes Gestational Diabetes)
Genzyme, a Sanofi Company

Approved for marketing

Alglucosidase Alfa Temporary Access Program (ATAP)

Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2 | Pompe Disease (Late-Onset)

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Dietary Nitrate and Exercise to Augment Exercise Training Benefits in Subjects With DM+PAD (DM+PAD)

Peripheral Arterial Disease | Type II Diabetes Mellitus

United States
National Cancer Institute (NCI)

Terminated

Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma

Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone... and other conditions

United States
Genzyme, a Sanofi Company

Recruiting

Pompe Pregnancy Sub-Registry

Pompe Disease (Late-onset) | Glycogen Storage Disease Type II (GSD-II) | Glycogenesis 2 Acid Maltase Deficiency

Croatia, United States, Italy, Belgium, Czechia
Mayo Clinic
National Cancer Institute (NCI)

Completed

Rituximab With or Without Yttrium Y-90 Ibritumomab Tiuxetan in Treating Patients With Untreated Follicular Lymphoma

Ann Arbor Stage I Grade 1 Follicular Lymphoma | Ann Arbor Stage I Grade 2 Follicular Lymphoma | Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann... and other conditions

United States
Wake Forest University Health Sciences
Orthopaedic Trauma Association; Orthopaedic Research and Education Fund

Completed

A Study of Immediate and Delayed Closure of Type II and IIIa Open Tibia Fractures

Type II and IIa Open Tibia Fractures

United States
Wroclaw Medical University

Completed

Photobiomodulation of Orthodontic Mini-implants by a 635nm Diode Laser

Malocclusion, Angle Class II

Poland
Arbeitsgemeinschaft medikamentoese Tumortherapie
Amgen

Terminated

Concurrent Induction Chemoimmunotherapy With Epirubicine, Oxaliplatin, Capecitabine and Panitumumab in KRAs Wild-type, Resectable Type II Gastric Adenocarcinoma

KRAS Wild Type | Resectable Type II Gastric Adenocarcinoma

Austria
Rigshospitalet, Denmark
Groupe Hospitalier Pitie-Salpetriere

Completed

Effect of Bezafibrate on Muscle Metabolism in Patients With Fatty Acid Oxidation Defects (Bezafibrate)

Carnitine Palmitoyltransferase II Deficiency | Very Long Chain Acyl Coa Dehydrogenase Deficiency

Denmark
Instituto de Investigacion Sanitaria La Fe

Completed

Effect of Allopurinol Administration on the Prevention of Muscle Mass Loss in Subject Immobilized.

Patients With Grade II Ankle Sprain

Spain
Pusan National University Hospital
Pusan National University Yangsan Hospital

Unknown

Nasogastric Tube Insertion Using Cook Airway Exchange Catheter in Anesthetized Patients

Elective Surgery of Gastrointestinal Tract | 100 Adults Aged Between 20 and 70 Years Old | ASA Physical Status of I or II

Korea, Republic of
Cedars-Sinai Medical Center

Recruiting

Patient-Centered Communication of Life Expectancy Estimates in Genitourinary Malignancies

Prostate Cancer Stage II | Prostate Cancer Stage I | Bladder Cancer Stage II | Kidney Cancer Stage I

United States
Centre Hospitalier Universitaire, Amiens
Merck Serono International SA

Completed

May Metformin be Used in Renal Failure?

Renal Disorder Associated With Type II Diabetes Mellitus

France
Rawda Hesham Abd ElAziz

Recruiting

Clinical Performance of Advanced Self- Adhesivee Resin Composite Hybrid Restorations.

Caries,Dental | Caries Class II

Egypt
Eastern Cooperative Oncology Group

Completed

Double Blind Phase III Trial of Effects of Low Dose 13-Cisretinoic Acid on Prevention of Second Primaries in Stages I-II Head and Neck Cancer

Stage I-II Head and Neck Cancer
Sichuan Academy of Medical Sciences

Unknown

Metabolomics Dynamics Study for Severe Patient

Age:18-70 Years | Acute Severe Disease | Acute Physiology And Chronic Health Evaluation(APACHE)II>10

China
Maggie's Pearl, LLC

Active, not recruiting

Oral Epalrestat Therapy in Pediatric Subjects With PMM2-CDG

Pmm2-CDG | Phosphomannomutase 2 Deficiency | Phosphomannomutase 2 Congenital Disorder of Glycosylation | Phosphomannomutase II Congenital Disorder of Glycosylation | Phosphomannomutase II Deficiency

United States
Damascus University

Completed

Laser-assisted Flapless Corticotomy in Accelerating Canine Retraction

Class II Division 1 Malocclusion | Protrusion, Incisor | Maxillary Prognathism

Syrian Arab Republic
Paolo Caimi, MD
National Cancer Institute (NCI)

Completed

Curcumin and Cholecalciferol in Treating Patients With Previously Untreated Stage 0-II Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Stage 0 Chronic Lymphocytic Leukemia | Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia | Contiguous Stage II Small Lymphocytic Lymphoma | Noncontiguous Stage II Small Lymphocytic Lymphoma | Stage I Small Lymphocytic Lymphoma

United States
Endotronix, Inc.

Recruiting

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Heart Failure NYHA Class II | Heart Failure NYHA Class III

United States
Memorial Sloan Kettering Cancer Center
Tesaro, Inc.

Recruiting

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Solid Tumor | Solid Tumor, Adult | Rectal Adenocarcinoma | Clinical Stage: Stage II (T3-4, N-) | Stage III (Any T, N+)

United States
3M

Completed

Clinical Study of Filtek™ Bulk Fill Posterior Restorative in Class I and II Restorations

Dental Caries Class II | Dental Caries Class I

China
University of Pennsylvania
Amgen

Enrolling by invitation

Early Metabolic Adaptations to SGLT2 Inhibition in Heart Failure (EMAS-HF)

Heart Failure | Heart Failure NYHA Class II | Heart Failure NYHA Class III

United States
Fundació Institut de Recerca de l'Hospital de la...
Spanish Clinical Research Network - SCReN; Grupo de Bioingenieria y Telemedicina...

Completed

Individualized Telemedical Assistance for Lifestyle Modification in the Treatment of Obesity and Cardiometabolic Risk Prevention (PREDIRCAM 2)

Obesity Type I and II

Spain
Stanford University
AstraZeneca

Completed

Seroquel in the Treatment of Dysphoric Hypomania in Bipolar II

Bipolar II Disorder

United States
Novartis

Completed

Evaluate the Efficacy and Safety of Diclofenac Diethylamine 2.32% Gel Applied Twice or Three Times Daily in Patients With Acute Ankle Sprain

Grade I/II Ankle Sprain

Germany
Medtronic Cardiac Rhythm and Heart Failure

Recruiting

Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure (ALLEVIATE-HF)

Heart Failure NYHA Class II | Heart Failure NYHA Class III

United States
Stephanie Shimizu
University of Southern California

Recruiting

Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride

Dental Caries in Children | Dental Caries | Dental Caries Class II

United States
Riphah International University

Completed

Cycle Ergometer Training and Heart Failure on Heart Rate Recovery and Mind Fullness

Heart Failure NYHA Class II | Heart Failure NYHA Class I

Pakistan
Xiyuan Hospital of China Academy of Chinese Medical...

Unknown

Baduanjin Exercise for Patients With Chronic Heart Failure on Phase II Cardiac Rehabilitation (BEPCR)

Rehabilitation With CHF; NYHA Class I or II

China
Cairo University

Unknown

Study of the Relationship Between Blood Groups,RH and Skeletal Malocclusion : a Cross Sectional Study

Class III Malocclusion | Class II Malocclusion
Universidad de La Frontera
University of Chile

Not yet recruiting

Comprehensive Hybrid Cardiac Rehabilitation Trial on Heart Failure (COCREATIONHF)

Heart Failure NYHA Class II | Heart Failure NYHA Class III

Chile
Abbott Medical Devices

Enrolling by invitation

CardioMEMS HF System Real-World Evidence Post-Approval Study

Heart Failure NYHA Class II | Heart Failure NYHA Class III

United States
Medical University of South Carolina
Milken Institute

Completed

Evaluating the Hypothesized Mechanism of Action of N-acetylcysteine for Bipolar Disorder

Bipolar Disorder | Bipolar I Disorder | Bipolar II Disorder

United States
Damascus University

Completed

Evaluation of Root Resorption During the Correction of Deep Bite With the Help of Laser Irradiation

Deep Overbite

Syrian Arab Republic
Abbott Medical Devices
Thoratec Corporation

Completed

PREVENtion of HeartMate II Pump Thrombosis (PREVENT)

HeartMate II Pump Thrombosis

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Clinical Management of Argatroban in Patients With Heparin Induced Thrombocytopenia Type II

Heparin-induced Thrombocytopenia Type II

France
New York Medical College

Completed

Human Placental-Derived Stem Cell Transplantation (HPDSC)

Mucopolysaccharidosis I | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Fucosidosis | Gaucher... and other conditions

United States
McMaster University

Not yet recruiting

Nutritional Therapy in Late-onset Pompe Disease (PDT-MIS)

Obesity | Lysosomal Storage Diseases | Muscle Loss | Glycogen Storage Disease Type II | Pompe Disease | Nutrition Poor | Glycogen Storage Disease Type II, Adult | Glycogen Storage Disease Type II Late Onset
Genzyme, a Sanofi Company

Completed

A Study of rhGAA in Patients With Late-Onset Pompe Disease

Pompe Disease (Late-onset) | Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2

Netherlands
Genzyme, a Sanofi Company

Completed

Safety and Effectiveness Study of rhGAA in Patients With Advanced Late-Onset Pompe Disease Receiving Respiratory Support

Pompe Disease (Late-onset) | Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2

France
National Cancer Institute (NCI)

Completed

Alvocidib, Fludarabine Phosphate, and Rituximab in Treating Patients With Lymphoproliferative Disorders or Mantle Cell Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenström Macroglobulinemia and other conditions

United States

Clinical Trials on Mucopolysaccharidosis II

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CROs in Azerbaijan

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