Clinical Trials on Multidrug Resistent Bacteria in South Africa

Total 913 results

GlaxoSmithKline

Completed

A Sourcing Study to Collect Human Blood Samples From Healthy Adults

Meningitis, Meningococcal

Australia, Germany
Okogen

Active, not recruiting

OKG-0301 for the Treatment of Acute Adenoviral Conjunctivitis (RUBY)

Adenoviral Conjunctivitis

Australia
Maastricht University Medical Center
National Institute for Public Health and the Environment (RIVM); ZonMw: The... and other collaborators

Completed

Transmission of Genital and Extra-genital Chlamydia Trachomatis Infections in Women (FemCure)

Chlamydia Trachomatis Infection

Netherlands
Pfizer

Completed

Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Adults 60 Through 64 Years of Age

Pneumococcal Infections

United States
Royal North Shore Hospital

Unknown

Citriodiol® and Impetigo

Impetigo

Australia
GlaxoSmithKline

Completed

A Three-Part Study Of GSK580416 In Healthy Subjects

Infections, Bacterial | Respiratory Tract Infection

Australia
Medecins Sans Frontieres, Spain

Completed

Evaluation of Point-of-care Ultrasound in Children From 6 Months to 15 Years With Presumptive Tuberculosis

Tuberculosis

Guinea-Bissau, South Sudan
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

REMEMBER: Reducing Early Mortality & Morbidity by Empiric Tuberculosis (TB) Treatment (REMEMBER)

HIV Infection

Peru, Malawi, Uganda, South Africa, India, Haiti, Zambia, Zimbabwe, Brazil, Kenya
Hasanuddin University

Not yet recruiting

Oral Vitamin D and Toll Like Receptor in Spondylitis Tuberculosis

Tuberculosis | Spondylitis

Indonesia
Pfizer

Completed

Immunogenicity and Safety Study of 1 and 2 Doses of GlaxoSmithKline (GSK) Biologicals' Meningococcal Vaccine MenACWY-TT (GSK134612) in Toddlers, Persistence up to 5 Years After Vaccination and Co-administration With Pfizer's Prevenar 13™Vaccine

Infections, Meningococcal

Australia, Canada, Czechia, Panama, South Africa, Turkey
Pfizer

Terminated

Colombia Epidemiologic Surveillance Study (LEAP II)

Pneumonia | Sepsis | Bacteremia | Meningitis

Colombia, Brazil, Costa Rica
Wockhardt
ACM

Completed

Phase II Study of Oral Nafithromycin in CABP

Community-Acquired Bacterial Pneumonia (CABP)

United States
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

Phase 1 Oral QPX7831 SAD and MAD in Healthy Adults

Bacterial Infections

Australia, United States
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

P1 Single and Multiple Ascending Dose (SAD/MAD) Study of IV QPX7728 Alone and Combined With QPX2014 in NHV

Bacterial Infections

Australia, United States
Bugworks Research Inc.
Avance Clinical Pty Ltd.

Terminated

The Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of BWC0977 in Healthy Adult Volunteers

Bacterial Infections | Infectious Diseases

Australia
Bugworks Research Inc.
Avance Clinical Pty Ltd.

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of BWC0977 in Healthy Volunteers

Bacterial Infections | Infectious Diseases

Australia
GlaxoSmithKline
Affinivax, Inc.

Active, not recruiting

A Phase 2 Study to Evaluate the Safety, Tolerability, and Immunogenicity of AFX3772 Vaccine in Healthy Infants

Pneumococcal Infections | Pneumonia, Pneumococcal | Pneumonia, Bacterial

United States
Holdsworth House Medical Practice
Rigel Pharmaceuticals

Completed

Study of the Effect of Fostamatinib Upon Cutaneous Inflammation in the Setting of Hidradenitis Suppurativa

Hidradenitis Suppurativa

Australia
Henry M. Jackson Foundation for the Advancement...
Infectious Diseases Clinical Research Program

Completed

Screening for Latent Tuberculosis Infection (LTBI) in US Army Recruits (LTBI)

Latent Tuberculosis Infection

United States
Azora Therapeutics Australia Pty Ltd

Completed

Study of Efficacy and Safety of Investigational Treatment in Patients With Hidradenitis Suppurativa

Hidradenitis Suppurativa

Australia
National Institute of Allergy and Infectious Diseases...
TB Alliance

Not yet recruiting

Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)

Pulmonary Tuberculosis

Botswana, Brazil, Haiti, India, Kenya, Malawi, Mexico, Peru, Philippines, South Africa, Thailand, Uganda, Zimbabwe
GlaxoSmithKline

Completed

Immunogenicity, Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' MenACWY-TT Vaccine Administered 6 Years Post-MenC Primary Vaccination in Healthy Subjects Who Were 12-18 Months at Primary Vaccination

Infections, Meningococcal

Australia
Centers for Disease Control and Prevention
Tuberculosis Trials Consortium

Recruiting

Short-course Regimens for the Treatment of Pulmonary Tuberculosis (CRUSH-TB)

Tuberculosis, Pulmonary | Tuberculosis Infection

Canada, United States, Haiti, South Africa, Uganda, Vietnam
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Immunogenicity and Tolerability of Meningococcal Group B Vaccine in Healthy Adults

Meningitis, Meningococcal

Australia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis (STRIDE)

HIV Infection | Tuberculosis

United States, Peru, Kenya, Malawi, Uganda, Brazil, South Africa, Zimbabwe, India, Thailand, Botswana, Haiti, Zambia
GlaxoSmithKline

Active, not recruiting

Safety and Efficacy of GSK Neisseria Gonorrhoeae GMMA (NgG) Investigational Vaccine When Administered to Healthy Adults 18 to 50 Years of Age.

Sexually Transmitted Diseases

United States, Germany, Philippines, France, Spain, South Africa, United Kingdom, Brazil
Scynexis, Inc.

Completed

Study to Evaluate the Safety and Efficacy of the Coadministration of Ibrexafungerp (SCY-078) With Voriconazole in Patients With Invasive Pulmonary Aspergillosis (SCYNERGIA)

Invasive Pulmonary Aspergillosis

United States, Belgium, Canada, Germany, South Africa
KNCV Tuberculosis Foundation
Kenya Medical Research Institute; Kenya National AIDS & STI Control Programme; Centres for Disease Control and Prevention, Kenya... and other collaborators

Completed

Feasibility and Effectiveness of Community Based Isoniazid Preventive Therapy in Kenya (IPT)

Tuberculosis

Kenya
University of Adelaide

Completed

The Long-term Impact of Invasive Meningococcal Disease in Australian Adolescents and Young Adults (AMEND)

Meningococcal Infections | Neisseria Infection | Neisseria Meningitis Sepsis

Australia
Scynexis, Inc.

Completed

Open-Label Study to Evaluate the Efficacy and Safety of Oral Ibrexafungerp (SCY-078) in Patients With Candidiasis Caused by Candida Auris (CARES) (CARES)

Candidemia | Candidiasis, Invasive

Pakistan, India, United States, South Africa
Emergent BioSolutions

Completed

Immunogenicity, Safety and Tolerability of the Typhoid Fever Vaccine Candidate M01ZH09 in Healthy Adults

Typhoid

United States
GlaxoSmithKline

Active, not recruiting

A Study on the Safety, Tolerability and Immune Response of Meningococcal Combined ABCWY Vaccine in Healthy Infants

Infections, Meningococcal

Finland, Poland, Spain, United Kingdom, Germany, South Africa, Dominican Republic, Israel, Honduras
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity of V114 in Children Infected With Human Immunodeficiency Virus (HIV) (V114-030/PNEU-WAY PED) (PNEU-WAY PED)

Pneumococcal Infections

South Africa, Thailand, Ukraine
BioMérieux

Completed

Performance Evaluation of the VIDAS TB-IGRA Assay.

Active Tuberculosis | Latent Tuberculosis Infection | Non-Tuberculous Mycobacterial (NTM) Pneumonia

United States, France, United Kingdom, India, Brazil, Georgia, Italy, Mexico, South Africa
Chantal Kats

Recruiting

External Validation of the Beta-lactam Target Non-attainment (BATMAN) Risk Score in Adult ICU Patients: a Diagnostic Multivariate Predictive Risk Model (BATMAN)

Infection, Bacterial | Beta-lactam Antibiotics | Critical Care | Risk Model | Therapeutic Drug Monitoring

Netherlands
Xennials Therapeutics Australia Pty Ltd
Pinotbio, Inc.

Terminated

NTX-301 Monotherapy in Advanced Solid Tumours and in Combination With Platinum-based Chemotherapy in Advanced Ovarian & Bladder Cancer and in Combination With Temozolomide in High-grade Glioma

Advanced Solid Tumor | High-grade Glioma | Platinum-Resistant Ovarian Cancer | Platinum-Resistant Urothelial Carcinoma

Australia
Centers for Disease Control and Prevention
Bayer; Global Alliance for TB Drug Development

Completed

TBTC Study 28: Moxifloxacin Versus Isoniazid for TB Treatment

Tuberculosis

Uganda, United States, South Africa, Canada, Brazil, Spain
Medecins Sans Frontieres, Spain
Ministry of Health, Guinea-Bissau; Institute of Tropical Medicine, University... and other collaborators

Completed

Evaluation of Xpert MTB/RIF Ultra in Stools and Urine to Improve Tuberculosis Diagnosis in Children

Tuberculosis | Pediatric Infectious Disease

Guinea-Bissau, South Sudan
Yunia Irawati

Completed

Modified Tarsorrhaphy vs Gold Weight Implant for Paralytic Lagophthalmos in Leprosy Patients

Paralytic Lagophthalmos | Leprosy--Patients

Indonesia
Eli Lilly and Company

Completed

A Study in Relapse Prevention of Treatment-Resistant Depression

Treatment Resistant Depression

United States, Argentina, Russian Federation, South Africa, India, Turkey, Puerto Rico, Mexico
Biomedical Advanced Research and Development Authority
Rho, Inc.

Completed

BARDA Securing Anthrax Immunity For the Elderly (B-SAFE)

Anthrax

United States
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield Hallam University

Unknown

A COMbined progRamme of Exercise and Dietary ADvice in mEn With Castrate Resistant Prostate Cancer (COMRADE)

Prostate Cancer | Prostatic Neoplasms, Castration-Resistant

United Kingdom
Bill & Melinda Gates Medical Research Institute
Bill and Melinda Gates Foundation; Wellcome Trust

Recruiting

Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and Adults

Tuberculosis

Indonesia, Kenya, Malawi, Mozambique, South Africa, Vietnam, Zambia
University of Bamenda
Ministry of Science and Technology of the People´s Republic of China; National...

Completed

Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa

Drug Resistant Malaria Due to Plasmodium Falciparum

Cameroon
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Phase 2 Safety and Immunogenicity Study for an Anthrax Vaccine Using 3 Schedules and Two Dose Levels

Anthrax

United States
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity of V116 in Adults Living With Human Immunodeficiency Virus (HIV) (V116-007, STRIDE-7)

Pneumococcal Disease

United States, Belgium, Chile, France, South Africa, Thailand
Centers for Disease Control and Prevention

Completed

TBTC Study 27: Moxifloxacin vs Ethambutol for TB Treatment

Tuberculosis, Pulmonary

Uganda, United States, Canada, South Africa
Pfizer

Completed

Evaluation of a 3-dose Vaccination Regimen With One of Three Ascending Dose Levels of Clostridium Difficile Vaccine With or Without Adjuvant in Healthy Adults Aged 50 to 85 Years

Clostridium Difficile Associated Disease

United States
GlaxoSmithKline

Completed

Immunogenicity & Reactogenicity of Boostrix 10 Years After Previous Booster Vaccination in Study NCT01267058

Tetanus | Diphtheria | Acellular Pertussis | Diphtheria-Tetanus-acellular Pertussis Vaccines

Australia
Emergent BioSolutions
Department of Health and Human Services

Completed

Immunogenicity and Safety Study of a Three-Dose BioThrax® Regimen for Post-Exposure Prophylaxis in Healthy Adults

Anthrax

United States

Clinical Trials on Multidrug Resistent Bacteria in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Tunisia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations