Clinical Trials on Multiple Myeloma and Malignant Plasma Cell Neoplasms

Total 34451 results

Takeda

Completed

Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication"

Gastric/Duodenal Ulcer, Gastric MALT Lymphoma, Idiopathic Thrombocytopenic Purpura, or H. Pylori Gastritis, and Other

Japan
Deciphera Pharmaceuticals LLC

Recruiting

Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway

Melanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene Mutation

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

T-Cell Infusion, Aldesleukin, and Utomilumab in Treating Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Carcinoma | HLA-A*0201 Positive Cells Present | COL6A3 Positive | PRAME Positive

United States
William Shomali
Incyte Corporation

Recruiting

Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

Eosinophilia | Hypereosinophilic Syndrome | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells | Splenomegaly | Hepatomegaly | Chronic Eosinophilic Leukemia, Not Otherwise Specified | JAK2 Gene Mutation | BCR-JAK2 Fusion Protein Expression | Blasts 20 Percent or Less of Peripheral Blood White... and other conditions

United States
Masonic Cancer Center, University of Minnesota

Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

Cytokine Release Syndrome | Immune and Microbial Reconstitution | Systemic Viral Infection | Acute-graft-versus-host Disease | Chronic Graft-versus-host-disease | Recurrent Malignancy | Allogenic Related Donors | Cell Therapy/Immunotherapy Patients

United States
Medical College of Wisconsin
Children's Hospital and Health System Foundation, Wisconsin

Recruiting

CAR-20/19-T Cells in Patients With Relapsed/Refractory B Cell ALL (CAR-20/19-T)

Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia, Pediatric | Acute Lymphoblastic Leukemia, in Relapse | Acute Lymphoblastic Leukemia Recurrent | Acute Lymphoblastic Leukemia With Failed Remission | Acute Lymphoblastic Leukemia Not Having Achieved Remission

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Hu5F9-G4 (Magrolimab), to the Usual Chemotherapy Treatment (Mogamulizumab) in T-Cell (a Type of Immune Cell) Lymphoma That Has Returned After Treatment or Does Not Respond to Treatment

Mycosis Fungoides | Sezary Syndrome | Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v8 | Stage II Mycosis Fungoides and Sezary Syndrome AJCC v8 | Stage III Mycosis Fungoides and Sezary Syndrome AJCC v8 | Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v8 | Recurrent Mycosis Fungoides... and other conditions

United States
Charlotte Niemeyer, MD

Completed

Serial Analysis of Chimerism in Patients With Refractory Cytopenia (RC) Transplanted With Reduced Intensity Conditioning (RIC)

Myelodysplastic Syndrome (MDS) | Refractory Cytopenia of Childhood | Hematopoietic Stem Cell Transplantation (SCT) | Reduced Intensity Conditioning (RIC)

Germany
Fondazione Don Carlo Gnocchi Onlus

Recruiting

Clinical and Instrumental Treatment's Predictors in Subjects With Neurological Diseases Using G-EO Robotic System

Stroke | Multiple Sclerosis | Parkinson Disease | Acquired Brain Injury

Italy
Daniel Claassen

Recruiting

[18F]F-DOPA Imaging in Patients With Autonomic Failure

Parkinson Disease | Multiple System Atrophy | Pure Autonomic Failure | Dementia With Lewy Bodies | Autonomic Failure

United States
Göteborg University
The Swedish Research Council; Swedish Council for Working Life and Social Research

Completed

Finding the Right Words in Neurogenic Communication Disorders

Stroke | Multiple Sclerosis | Parkinson Disease | Aphasia | Anomia

Sweden
IRCCS San Raffaele

Recruiting

Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy

Bladder Cancer | Muscle-Invasive Bladder Carcinoma | Radical Cystectomy | Urinary Diversion | Bladder Urothelial Carcinoma | Progression, Disease | Bladder Cancer Stage II | Bladder Cancer Stage IV | Muscle Invasive Bladder Urothelial Carcinoma | Neobladder | Bladder Cancer TNM Staging | Bladder Cancer Stage... and other conditions

Italy
Assistance Publique - Hôpitaux de Paris

Completed

Epidemiological Characteristics of COVID-19 in Patients With MS or NMO (COVISEP)

COVID-19 | Multiple Sclerosis | NMO Spectrum Disorder

France
Affiliated Cancer Hospital & Institute of Guangzhou...

Unknown

Clinical Pharmacokinetics of TKIs in Chinese Patients of Hepatitis B (HBV)

Hepatitis B | Non Small Cell Lung Cancer

China
The Hospital for Sick Children

Active, not recruiting

International Rare Histiocytic Disorders Registry (IRHDR) (IRHDR)

Rare Histiocytic Disorders (RHDs) | Juvenile Xanthogranuloma (JXG) | Reticulohistiocytoma (Epithelioid Histiocytoma) | Xanthoma Disseminatum (XD) | Multicentric Reticulohistiocytosis (MRH) | Systemic Juvenile Xanthogranuloma | Erdheim-Chester Disease (ECD) | Multi-system Rosai-Dorfman Disease (RDD)

Canada, United States, Poland, Argentina, Austria, Czechia, Germany, Italy, Russian Federation, Spain
Dartmouth-Hitchcock Medical Center

Completed

Neurology Inpatient Clinical Education Trial

Multiple Sclerosis | Encephalitis | Seizures | Headache | Myasthenia Gravis | Meningitis | Parkinsonism | Spondylosis | Guillain-Barre Syndrome | Vestibular Disorder | Normal Pressure Hydrocephalus

United States
IRCCS Centro Neurolesi "Bonino-Pulejo"

Completed

The Efficacy of VESPA 2.0 for Cognitive Rehabilitation in Patients With Mild Cognitive Impairment

Multiple Sclerosis | Neurodegenerative Diseases | Alzheimer Disease | Cognitive Decline | Parkinson Disease Dementia

Italy
Nantes University Hospital

Completed

Analysis of the Enteric Nervous System Using Colonic Biopsies (ColoBioParker)

Parkinson's Disease | Multiple System Atrophy | Progressive Supranuclear Palsy

France
Xperiome
The Touro College and University System

Withdrawn

Medication Adherence and Non-adherence in Adults With Rare Disease

Hemophilia A | Hemophilia B | Idiopathic Pulmonary Fibrosis | Myasthenia Gravis | Cystic Fibrosis | Sickle Cell Disease
CND Life Sciences

Completed

Synuclein-One Study

Parkinson Disease | Multiple System Atrophy | Pure Autonomic Failure | Dementia With Lewy Bodies

United States
National Institute of Neurological Disorders and...

Completed

Diagnosis and Natural History Study of Patients With Neurological Conditions

Parkinson's Disease | Dementia | Multiple System Atrophy | Alzheimer's Disease | Movement Disorder

United States
National Cancer Institute (NCI)

Withdrawn

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Cervical Carcinoma | Recurrent Melanoma | Vaginal Carcinoma | Esophageal Carcinoma | Mucosal Melanoma | Mucosal Melanoma of the Head and Neck | Oral Cavity Mucosal Melanoma | Stage II Vulvar Cancer AJCC v7 | Stage III Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 and other conditions

United States
Aarhus University Hospital

Completed

Post-thrombotic Syndrome After Deep Venous Thrombosis (DVT) in Patients Treated According to the NOPHO ALL2008 Protocol

Acute Lymphoblastic Leukemia | Post Thrombotic Syndrome

Denmark
Institut National de la Santé Et de la Recherche...

Recruiting

FARD (RaDiCo Cohort) (RaDiCo-FARD) (FARD)

Neurofibromatosis Type 1 | Ichthyosis | Ectodermal Dysplasia | Albinism | Pemphigus | Mucous Membrane Pemphigoid | Inherited Epidermolysis Bullosa | Palmoplantar Keratoderma | Incontinentia Pigmenti

France
University of Geneva, Switzerland
All India Institute of Medical Sciences, New Delhi; Swiss National Science... and other collaborators

Recruiting

Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia (MPGx-INDALL)

Drug Effect | Pediatric Cancer | Adverse Drug Event | Drug Interaction | ALL, Childhood | Drug Toxicity | Toxicity, Drug | Relapse Leukemia

India
Hospital General de Mexico

Completed

Clinical Characteristics of Patients With Leukemia and COVID-19

Covid19 | Leukemia, Acute | Leukemia, Lymphoblastic

Mexico
National Institutes of Health Clinical Center (CC)

Completed

Evaluation of Brain Lesions in HIV-infected Patients for Diagnosis of Primary Central Nervous System Lymphoma

HIV Infections | Lymphoma, AIDS-Related

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer (AMBASSADOR)

Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage III Ureter Cancer AJCC v7 | Locally Advanced Bladder Urothelial Carcinoma | Locally Advanced Ureter Urothelial Carcinoma | Locally Advanced Urothelial Carcinoma | Localized Renal Pelvis and Ureter Urothelial Carcinoma | Stage II Bladder... and other conditions

United States, Guam
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma

Metastatic Melanoma | Metastatic Uveal Melanoma | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage III Cutaneous... and other conditions

United States
National Cancer Institute (NCI)

Completed

Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma

Recurrent Childhood Medulloblastoma | Childhood High-grade Cerebral Astrocytoma | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Cerebellar Astrocytoma | Recurrent Childhood Cerebral Astrocytoma | Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor | Recurrent Childhood... and other conditions

United States
Vincent Mok

Recruiting

Neurodegenerative Diseases Registry (NDD Registry)

Parkinson Disease | Neurodegenerative Diseases | Multiple System Atrophy | Progressive Supranuclear Palsy

Hong Kong
University of Texas Southwestern Medical Center

Recruiting

Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging

Parkinson Disease | Multiple System Atrophy | Progressive Supranuclear Palsy

United States
Massachusetts General Hospital

Recruiting

PET Imaging Evaluation of [11C]SY08

Parkinson's Disease | Multiple System Atrophy | Dementia With Lewy Bodies | Healthy Controls

United States
National Cancer Institute (NCI)

Completed

Ixabepilone in Treating Young Patients With Refractory Solid Tumors

Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Ewing Sarcoma... and other conditions

United States
Rigshospitalet, Denmark

Recruiting

STAY-STRONG Study of Exercise Training During Chemotherapy (STAY-STRONG)

Quality of Life | Lymphoma, B-Cell | Exercise | Body Composition | Sarcopenia | Lymphoma, Hodgkin | Physical Functional Performance | Muscle, Skeletal | Patient Reported Outcome Measures

Denmark
University Hospital Olomouc
University Hospital Ostrava; Tomas Bata Hospital, Czech Republic; General University... and other collaborators

Recruiting

Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy

Cushing Syndrome | Pheochromocytoma | Adrenocortical Carcinoma | Adrenal Cortex Diseases | Adrenocortical Adenoma | Adrenal Tumor | Adrenalectomy; Status | Adrenal Mass | Adrenal Hyperplasia | Adrenal Disease | Adrenocortical Tumor | Conn Adenoma | Adrenal Gland Metastasis

Czechia
Beijing Friendship Hospital

Recruiting

Prospective Study of Immune Function and PD-1 Antibody Therapy Efficacy Predictors on CAEBV and EBV-HLH Patients

Chronic Active Epstein-Barr Virus Infection | Secondary Hemophagocytic Lymphohistiocytosis

China
Beijing Friendship Hospital

Recruiting

Rituximab Monotherapy for EBV-HLH and CAEBV

Chronic Active Epstein-Barr Virus Infection | Secondary Hemophagocytic Lymphohistiocytosis

China
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART C)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART A)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies (HEM-iSMART D)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
University of Edinburgh
NHS Lothian

Not yet recruiting

Digital App for Speech & Health Monitoring

Multiple Sclerosis | Parkinson Disease | Motor Neuron Disease | Dementia
Haukeland University Hospital
Nordlandssykehuset HF; Helse Møre og Romsdal HF; Helse Fonna HF; Oslo universitetssykehus... and other collaborators

Not yet recruiting

The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism (NADAPT)

Multiple System Atrophy | Progressive Supranuclear Palsy | Corticobasal Syndrome

Norway
IRCCS San Camillo, Venezia, Italy
IRCCS Centro San Giovanni di Dio Fatebenefratelli; Università Ca' Foscari Venezia

Recruiting

Exploring the Gut-Brain Axis in Ageing and Neurodegeneration (GutBrain)

Multiple Sclerosis | Healthy | Parkinson Disease | Prodromal Alzheimer's Disease

Italy
Loma Linda University
H. Lundbeck A/S

Withdrawn

Safety and Efficacy of Droxidopa for Fatigue in Patients With Parkinsonism

Parkinson Disease | Multiple System Atrophy | Progressive Supranuclear Palsy

United States
University of Aarhus

Recruiting

Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation

Constipation | Childhood Acute Lymphoblastic Leukemia | Neurofibromatosis 1 | Chronic Constipation With Overflow

Denmark
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers

Metastatic Adrenal Gland Pheochromocytoma | Stage III Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Locally Advanced Adrenal Gland Pheochromocytoma | Locally Advanced Paraganglioma | Metastatic Paraganglioma | Metastatic Parathyroid Gland Carcinoma and other conditions

United States
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
University of Washington
Pfizer

Completed

Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Recurrent B Lymphoblastic Lymphoma | Refractory B Lymphoblastic Lymphoma

United States
Ehab L Atallah

Terminated

Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia

Relapsed or Refractory Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia | Relapsed or Refractory Lymphoblastic Lymphoma

United States

Clinical Trials on Multiple Myeloma and Malignant Plasma Cell Neoplasms

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Romania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations