Clinical Trials on Multiple System Atrophy, Cerebellar Type

Total 42960 results

University of Exeter

Completed

Can Ultrasound be Used as a Measure of Muscle Quality? A Validation Study Comparing Ultrasound With MRI and MRS in Older and Younger Persons.

Muscle Atrophy

United Kingdom
Medical University Innsbruck

Recruiting

Medical Decision Making in Multiple System Atrophy (MeDeMSA)

Multiple System Atrophy

Austria
University Hospital, Bordeaux
Institut National de Recherche en Informatique et en Automatique

Recruiting

Differential Diagnosis Between Parkinson's Disease and Multiple System Atrophy Using Digital Speech Analysis - Part 2 (Voice4PD-MSA)

Parkinson Disease | Multiple System Atrophy

France
University Hospital, Toulouse

Completed

Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA (DOPS-AMS)

Multiple System Atrophy

France
Milton S. Hershey Medical Center

Completed

Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)

Parkinsonism | Parkinson's Disease (PD) | Multiple System Atrophy (MSA) | Progressive Supranuclear Palsy (PSP)

United States
University Hospital of Split
Slovenian Research Agency

Unknown

Effects of Variable Load Exercise on Aging Atrophy

Hypertension | Sarcopenia | Muscle Atrophy

Slovenia
Guy's and St Thomas' NHS Foundation Trust

Completed

The Use of Computed Tomography (CT) to Measure Skeletal Muscle Quantity and Quality in Patients Receiving ECMO

Critical Illness | Muscle Atrophy

United Kingdom
GlaxoSmithKline

Completed

31P MRS Ischaemic Exercise Optimisation and COPD

Atrophy, Muscular

United Kingdom
Ain Shams University

Unknown

National Registry for Egyptian Pediatric Neuromuscular Diseases

Muscular Dystrophy | Polyneuropathies | Spinal Muscular Atrophy | Muscle Diseases | Myasthenic Syndromes

Egypt
Changhua Christian Hospital

Recruiting

rTMS Improves Functions in Spinocerebellar Ataxia

Transcranial Magnetic Stimulation | Spinocerebellar Ataxias

Taiwan
Universitat Internacional de Catalunya
Universitat de Lleida

Completed

Core Stability Exercises and Hereditary Ataxia (Core-ataxia)

Cerebellar Ataxia | Spinocerebellar Degenerations | Hereditary Ataxia

Spain
Centre Hospitalier Universitaire de Nīmes
Institut de Recherches en Biothérapie

Active, not recruiting

Assessment of NfL and GFAP Levels, Atrophy of the Macula GCC by OCT and Whole Brain Atrophy by MRI to Predict Evolution of Neurological Disability in MS Patients (NFL OCT)

Multiple Sclerosis

France
AdventHealth Translational Research Institute

Active, not recruiting

Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes (RECOVER)

Type 2 Diabetes | Exercise | Muscular Atrophy | Sedentary Behavior | Pre-diabetes

United States
University Hospital, Bordeaux

Recruiting

Quality of Life of Caregivers and Patients Suffering From Multiple System Atrophy (QUA2-AMS)

Multiple System Atrophy

France
Peter Novak

Completed

Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin.

Parkinson Disease | Multiple System Atrophy

United States
China Medical University Hospital
Ministry of Science and Technology, Taiwan

Unknown

Exploit the Neural Source and the Feasibility of Transcranial Direct Current Stimulation for Freezing of Gait in Parkinson's Disease and Multiple System Atrophy

Parkinson's Disease | Multiple System Atrophy

Taiwan
University of Latvia
Karolinska Institutet; Lithuanian University of Health Sciences; Technion, Israel... and other collaborators

Completed

Volatile Markers in Digestive Cancer (VOLGACORE)

Gastric Cancer | Colorectal Cancer | Colorectal Adenoma | Intestinal Metaplasia | Atrophic Gastritis | H.Pylori Infection | Peptic Ulcer Disease | Normal Control | Average-risk General Population

Latvia, Lithuania
Biogen

No longer available

Expanded Access Program (EAP) for Nusinersen in Participants With Infantile-onset (Consistent With Type 1) Spinal Muscular Atrophy (SMA)

Infantile-onset Spinal Muscular Atrophy

New Zealand, Colombia, Turkey
Stinus Gadegaard Hansen
Odense University Hospital; Research Unit of Health Sciences, Hospital of South... and other collaborators

Recruiting

Zoledronic Acid for Prevention of Bone Loss After BAriatric Surgery (ZABAS) (ZABAS)

Bone Loss | Muscle Atrophy | Bariatric Surgery

Denmark
Assistance Publique - Hôpitaux de Paris

Completed

Study to Evaluate the Efficacy of Riluzole in Children and Young Adults With Spinal Muscular Atrophy (SMA) (ASIRI)

SMA

France
McGill University Health Centre/Research Institute...

Not yet recruiting

A Personalized Video-based Exercise Program for Fall Prevention in Frail and Pre-frail Older Adult

Frailty | Fall Injury | Old Age; Atrophy | Age-Related Atrophy | Age-Related Sarcopenia

Canada
Umm Al-Qura University

Unknown

The Effect of the Reverse Nordic Curl Exercise on Quadriceps Femoris Muscles Injury Rate Among Soccer Players

Quadriceps Muscle Atrophy | Quadriceps Tendon Rupture | Quadriceps Strained Tendon

Saudi Arabia
Hospices Civils de Lyon

Not yet recruiting

Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy (PHENO SMART)

Spinal Muscular Atrophy

France
Hoffmann-La Roche

Recruiting

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy (HINALEA 1)

Muscular Atrophy, Spinal

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients

Spinal Muscular Atrophy

Italy
First Affiliated Hospital of Fujian Medical University
Peking Union Medical College Hospital; Fujian Medical University Union Hospital

Recruiting

Antisense Oligonucleotide for Spinal Muscular Atrophy

Spinal Muscular Atrophy

China
Mahidol University

Recruiting

Prenatal Carrier Screening for Spinal Muscular Atrophy Among Thai Pregnant Women

Spinal Muscular Atrophy

Thailand
Assistance Publique - Hôpitaux de Paris

Recruiting

Quantification of Motor Function in Infants With Spinal Muscular Atrophy Treated With Innovative Therapies (IMUSMA)

Spinal Muscular Atrophy

France
Assistance Publique - Hôpitaux de Paris

Recruiting

French Register of Patients With Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy

France
Wan-Jin Chen

Recruiting

A Registered Cohort Study on SMA

Spinal Muscular Atrophy

China
Biogen

Active, not recruiting

Adult Spinal Muscular Atrophy (SMA) China Registry

Muscular Atrophy, Spinal

China
Hoffmann-La Roche

Active, not recruiting

A Study of Risdiplam (RO7034067) in Adult and Pediatric Participants With Spinal Muscular Atrophy (Jewelfish)

Spinal Muscular Atrophy

Belgium, United States, United Kingdom, France, Poland, Italy, Switzerland, Netherlands, Germany
Centre Hospitalier Universitaire de Liege
Queen Fabiola Children's University Hospital; Erasme University Hospital; Centre... and other collaborators

Active, not recruiting

Holter of Movement in Patients With SMA Undergoing Treatment.

Spinal Muscular Atrophy

Belgium
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants (SUNFISH)

Muscular Atrophy, Spinal

Belgium, United States, China, Spain, Japan, Canada, France, Poland, Brazil, Croatia, Italy, Russian Federation, Turkey, Germany, Serbia, United Kingdom
Centre Hospitalier Universitaire de Nice

Active, not recruiting

Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA® (SMAII)

Spinal Muscular Atrophy

France
Biogen

Completed

A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies (SHINE)

Spinal Muscular Atrophy

United States, Spain, Germany, United Kingdom, Australia, Japan, Canada, Belgium, France, Hong Kong, Italy, Korea, Republic of, Sweden, Turkey
Novartis Pharmaceuticals

Completed

Real-World Use of Novel Treatments in Patients With Spinal Muscular Atrophy (SMA): A Multi-Site Retrospective Chart Review of Pediatric SMA Patients Outside of the United States

Spinal Muscular Atrophy

United States
Biogen

Active, not recruiting

A Study of Nusinersen Among Participants With Spinal Muscular Atrophy Who Received Onasemnogene Abeparvovec (RESPOND)

Muscular Atrophy, Spinal

United States, Spain, Germany, Italy, Israel
Novartis Pharmaceuticals

Completed

An Open Label Study of LMI070 (Branaplam) in Type 1 Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy

Belgium, Germany, Italy, Russian Federation, Poland, Bulgaria, Denmark
NYU Langone Health
Winthrop University Hospital

Withdrawn

Pulmonary Function Test Changes and Respiratory Muscle Strength Trends in Spinal Muscular Atrophy Patients Receiving Nusinersen Treatments

Spinal Muscular Atrophy

United States
Catalyst Pharmaceuticals, Inc.

Completed

Controlled Trial to Evaluate Amifampridine Phosphate in Spinal Muscular Atrophy Type 3 Patients

Muscular Atrophy, Spinal

Italy
Biogen

Completed

An Open-label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy

Spinal Muscular Atrophy

United States
Biogen

Completed

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701)

Spinal Muscular Atrophy

United States
Hoffmann-La Roche

Completed

A Drug-drug Interaction Study With Risdiplam Multiple Dose and Midazolam in Healthy Participants

Spinal Muscular Atrophy

United States
Cytokinetics
Astellas Pharma Global Development, Inc.

Completed

A Study of CK-2127107 in Patients With Spinal Muscular Atrophy

Spinal Muscular Atrophy

United States, Canada
National Institute of Neurological Disorders and...

Completed

SMN Copy Number Distribution in Mali, West Africa

Spinal Muscular Atrophy

Mali
Kaohsiung Medical University Chung-Ho Memorial...
National Taiwan University Hospital; Mackay Memorial Hospital; China Medical... and other collaborators

Unknown

Natural History of Types 2 and 3 SMA in Taiwan

Spinal Muscular Atrophy

Taiwan
National Institute of Neurological Disorders and...

Completed

Measuring Levels of SMN in Blood Samples of SMA Patients

Spinal Muscular Atrophy

United States
University of Utah

Completed

Progressive Strength Training in Spinal Muscular Atrophy

Muscular Atrophy, Spinal

United States
Columbia University

Completed

Short and Long Term Treatment With 4-AP in Ambulatory SMA Patients

Spinal Muscular Atrophy

United States

Clinical Trials on Multiple System Atrophy, Cerebellar Type

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