Clinical Trials on Muscle Mitochondrial Function

Total 8611 results

Amazentis SA
University of Washington; Synteract, Inc.

Completed

Bioenergetics and Muscle Function Improvement With AMAZ-02 in Elderly Skeletal Muscle (ENERGIZE Trial)

Aging | Muscle Function | Mitochondrial Function, Bioenergetics

United States
Amazentis SA
Eurofins Optimed

Completed

A Single and Multiple Dose Study of AMAZ-02 to Evaluate Safety and Pharmacokinetics in Elderly Subjects

Aging | Muscle Function | Mitochondrial Dysfunction

France
Royal Devon and Exeter NHS Foundation Trust
University of Exeter

Completed

Increasing Mitochondrial Function on Skeletal Muscle Performance in Older Men (Rejuvenate)

Impaired Mitochondrial Function, Muscle Performance

United Kingdom
University of Exeter
Royal Devon and Exeter NHS Foundation Trust

Terminated

Assessing the Effects of Increased Mitochondrial Function Exercise Training on Muscle Performance (Rejuvenate2)

Impaired Mitochondrial Function, Muscle Performance

United Kingdom
Amazentis SA
KGK Science Inc.

Completed

AMAZ-02 Effect on Exercise ToLerance in Healthy, Overweight Middle Aged Subjects (ATLAS Trial) (ATLAS)

Overweight | Healthy Aging | Muscle Function, Mitochondrial Function

Canada
Ankara Yildirim Beyazıt University

Completed

Effect of Exercises on Hamstring Muscle Function, Injury Risk, Agility and Cognitive Function

Cognitive Function | Muscle Function | Hamstring Muscles | Turkish Get Up

Turkey
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Exogenous Ketosis During Bed Rest in Older Adults (KBR)

Muscle Atrophy | Cognitive Function | Muscle Protein Synthesis | Insulin Sensitivity | Muscle Strength | Functional Capacity | Physical Inactivity | Mitochondrial Function

Canada
Maastricht University
Wageningen University and Research; Top Institute Food and Nutrition; Netherlands...

Terminated

The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans

Cognitive Function | Ageing | Physical Function | Mitochondrial Function

Netherlands
Maastricht University

Terminated

NAD Supplementation Study (NADS)

Aging | Mitochondrial Function

Netherlands
University of Florida
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

Resveratrol to Enhance Vitality and Vigor in Elders (REVIVE)

Physical Function | Mitochondrial Function

United States
Christopher Bell

Recruiting

Ergogenic Properties of Magnesium Supplementation

Exercise Performance | Gut -Microbiota | Mitochondrial Function

United States
Stealth BioTherapeutics Inc.

Completed

A Phase 2 Study to Evaluate the Impact of MTP-131 (Bendavia™) on Skeletal Muscle Function in Elderly (MOTION)

Skeletal Muscle Mitochondrial Dysfunction in the Elderly

United States
Nottingham Trent University

Suspended

The Effects of 4 Week β-alanine Supplementation on Knee Extensor Contractile and Force Properties in the Over 60s

Muscle Function
University of Bath

Completed

Does Exercise Snacking Improve Muscle Function in Older Adults?

Muscle Function

United Kingdom
Nottingham Trent University

Completed

β-alanine Supplementation on Knee Extensor Contractile and Force Properties

Muscle Function
KGK Science Inc.
Lonza Inc.

Completed

A Pilot Clinical Trial on the Efficacy of Two Carnitine-Based Products on Muscle Function in Healthy Older Adults (15CAHL)

Muscle Function

Canada
University Medical Center Nijmegen
Orion Corporation, Orion Pharma

Completed

Effect of Levosimendan on Respiratory Muscle Function in Healthy Subjects (LSD1)

Respiratory Muscle Function

Netherlands
University of Belgrade
University of Primorska, Faculty of Health Sciences

Completed

Central and Peripheral Changes in Quadriceps Femoris Function After Different Types of Isometric Strength Training

Quadriceps Muscle Function

Serbia
The Hospital for Sick Children

Completed

A Single Case Study of Hypermetabolism

Hypermetabolism Due to Defect in Mitochondria | Luft Disease

Canada
Texas A&M University

Completed

Fish Oil T Cell Function

Cognitive Function | Muscle Strength

United States
Biofortis, Merieux NutriSciences

Recruiting

Phytochemicals on "Metabolic Aging" in Older Overweight Adults

Mitochondrial Functions

United States
University of Copenhagen
Hvidovre University Hospital; Bispebjerg Hospital; Team Denmark; Danmarks Fødevareforskning

Completed

Vitamin D Status and Muscle Function

Vitamin D Status | Muscle Function
The Swedish School of Sport and Health Sciences
Swedish Research Council for Sport Science

Completed

Dose-response Relationship Between Exercise and Health Outcomes

Glucose Intolerance | Mitochondrial Function

Sweden
Rowan University

Suspended

Effects of Fish Oil and Resistance Training on Muscle Mass and Function

Muscle Strength | Neuromuscular Function | Fat-free Masss

United States
Al-Azhar University
University Hospital Fattouma Bourguiba

Completed

Laparoscopic Assisted Dismembered Pyeloplasty Versus Open Pyeloplasty in (UPJO) With Poorly Function Kidney in Pediatrics

Uretro-pelvic Junction Obstruction | Poorly Function Kidney

Egypt
VA Office of Research and Development

Active, not recruiting

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

Cognitive Function | Functional Status

United States
Beijing Sport University

Completed

The Effect of Aquatic Rehabilitation on Knee Function in Anterior Cruciate Ligament Reconstruction Patients.

Anterior Cruciate Ligament Reconstruction | Hydrotherapy | Gait | Muscle Function

China
University of Copenhagen
University of Aarhus; Arla Foods; Arla Foods Ingredients

Completed

Effects of Milk Protein and Vitamin D on Children's Growth and Health (D-pro)

Appetite Regulation | Muscle Function | Cardiometabolic Health | Bone Health

Denmark
University of Exeter
P.volve LLC

Active, not recruiting

Female Muscle Enhancement (FemME)

Muscle Function

United Kingdom
Ankara Yildirim Beyazıt University

Completed

Effects of Delayed Muscle Pain on Respiratory Muscle Function

Exercise | Muscle Soreness | Respiratory Muscles | Respiratory Function Tests

Turkey
University of Washington
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Emory... and other collaborators

Completed

Trial of Oral Glutamine on Mitochondrial Function in CKD

Cardiovascular Disease | Sarcopenia | Endothelial Dysfunction | Kidney Disease | Muscle Mitochondrial Function

United States
University Hospital, Strasbourg, France

Completed

Protective Effects of L-arginine During Reperfusion by Femoropopliteal Bypass for Lower Limb Ischemic Syndrome in Humans

Skeletal Muscle Ischemia | Severe Lower Limb Ischemia | Mitochondrial Dysfunction

France
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; Medical Research Council Mitochondrial Biology Unit

Completed

Nicotinamide Riboside and Mitochondrial Biogenesis

Mitochondrial Diseases | Mitochondrial Myopathies | Progressive External Ophthalmoplegia | Progressive Ophthalmoplegia | Progressive; Ophthalmoplegia, External | Mitochondria DNA Deletion | MELAS

United Kingdom
National and Kapodistrian University of Athens

Completed

Redox Status and Immune Function

Skeletal Muscle Damage | Aseptic Inflammation | Skeletal Muscle Function

Greece
Ying Xiao

Unknown

Influence of Profound Muscle Relaxation on Muscle Trauma and Postoperative Pulmonary Function

Muscle Trauma | Profound Muscle Relaxation | Postoperative Analgesic Demand | Postoperative Pulmonary Function

China
Xuzhou Central Hospital
The Affiliated Hospital of Xuzhou Medical University

Not yet recruiting

rTMS in the Prevention and Treatment of Postoperative Executive Dysfunction

Functional Magnetic Resonance Imaging | Executive Function Disorder
Flávia Carvalho

Not yet recruiting

Effects of Cryotherapy on Upper Limb Balance Test

Functional Status | Muscle Tone
University Medical Center Nijmegen

Unknown

Role of Diaphragm Fatigue in Weaning From Mechanical Ventilation

Weaning | Respiratory Muscle Function

Netherlands
São Paulo State University

Not yet recruiting

Effects of Cryotherapy on Ankle Function

Functional Status | Muscle Tone
São Paulo State University

Not yet recruiting

Effects of Cryotherapy on Knee Function

Functional Status | Muscle Tone
Bezmialem Vakif University

Completed

Increased Femoral Anteversion and Physical Performance

Muscle Strength | Functional Capacity | Functional Performance | Flexibility | High Femoral Anteversion

Turkey
University of Aarhus
Novo Nordisk A/S

Enrolling by invitation

Cardiac Mitochondrial Function After Heart Transplantation (ENERGY-HTX)

Cardiac Allograft Vasculopathy | Acute Cellular Graft Rejection | Mitochondrial Function | Primary Graft Failure

Denmark
University of Chile
Asociación Chilena de Nutrición Clínica, Obesidad y Metabolismo

Completed

Muscle Assessment in Women Who Have Undergone Roux-en-Y Gastric Bypass Surgery (FUBA)

Muscle Function, Handgrip Strength Test

Chile
Chung Shan Medical University

Not yet recruiting

Pharmacokinetic Effect of AstraGin on Whey Protein Absorption and Muscle Function in Healthy Subjects

Pharmacokinetic Effect of AstraGin on Whey Protein Absorption and Muscle Function in Healthy Subjects

Taiwan
Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
McGill University Health Centre/Research Institute...

Recruiting

Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome (dC-dT-MDS)

Mitochondrial Diseases | Mitochondrial Encephalomyopathy | Mitochondrial Encephalopathy | Mitochondrial DNA Depletion | Mitochondrial Metabolism Disorders

Canada
Stealth BioTherapeutics Inc.

Completed

Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study (MMPOWER-2)

Primary Mitochondrial Disease

United States
Gdansk University of Physical Education and Sport
University of Southampton; Medical University of Gdansk

Completed

Omega-3 Supplementation Combined With Endurance Training Improve Running Economy in Recreational Runners.

Effect of Omega-3 Supplementation on Exercise Performance and Muscle Tissue Functions

Poland
Stealth BioTherapeutics Inc.

Terminated

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

Primary Mitochondrial Disease

United States
Rigshospitalet, Denmark
University of Copenhagen

Recruiting

Human Mitochondrial Stress-driven Obesity Resistance (MITO-OB-RES)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Disorder

Denmark

Clinical Trials on Muscle Mitochondrial Function

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