Clinical Trials on Muscle Hypotonia

Total 3787 results

Karolinska Institutet
International Clinic of Rehabilitation, Ukraine

Completed

Evaluation of INRS With BCSK in Children With Spastic Bilateral Cerebral Palsy: a Randomized Controlled Trial.

Spastic Diplegia Cerebral Palsy

Ukraine
Jazz Pharmaceuticals

Completed

A Study of the Safety and Effectiveness of Sativex®, for the Relief of Symptoms of Spasticity in Subjects, From Phase B, With Multiple Sclerosis (MS)

Multiple Sclerosis | Spasticity

United Kingdom
Jazz Pharmaceuticals

Completed

A Randomized Study of Sativex on Cognitive Function and Mood: Multiple Sclerosis Patients

Multiple Sclerosis | Spasticity

Czechia
Joanne Kurtzberg, MD
The Robertson Foundation

Completed

A Randomized Study of Autologous Umbilical Cord Blood Reinfusion in Children With Cerebral Palsy

Cerebral Palsy | Spastic Cerebral Palsy | CP

United States
RVL Pharmaceuticals, Inc.
Osmotica Pharmaceutical US LLC

Completed

Efficacy Study of Arbaclofen to Treat Spasticity in Multiple Sclerosis

Multiple Sclerosis | Spasticity

United States, Russian Federation, Ukraine
The University of Texas Health Science Center,...
Allergan

Completed

Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity

Stroke | Brain Injuries | Spasticity

United States
Cairo University

Unknown

Effect of Spring Gravity Bar on Gait Pattern in Children With Spastic Diplegia

Spastic Diplegia Cerebral Palsy

Egypt
Huons Co., Ltd.

Unknown

A Single Center, Phase I Clinical Trial to Evaluate the Safety of LIZTOX Inj in the Treatment of Post Stroke Upper Limb Spasticity

Post Stroke Upper Limb Spasticity

Korea, Republic of
Ipsen

Completed

Spasticity and Treatment Satisfaction Among Stroke Survivors (REBOT)

Spasticity as Sequela of Stroke

France
Hacettepe University

Completed

Effects of Mirror Therapy Combined With Progressive Strength Training in Unilateral Spastic Cerebral Palsy

Spastic Hemiplegic Cerebral Palsy

Turkey
Cairo University

Completed

Extracorporeal Shock Wave Therapy Versus Functional Electrical Stimulation on Spasticity, Function and Gait Parameters in Hemiplegic Cerebral Palsy

Children With Cerebral Palsy

Egypt
University of Nove de Julho
Daniela Aparecida Biasotto-Gonzalez; Claudia Santos Oliveira

Completed

Effect of Botulinum Toxin Type A Associated With Physical Therapy on Children With Spastic Cerebral Palsy

Physical Therapy | Cerebral Palsy, Spastic | Botulinum Toxin
Universidad Industrial de Santander

Unknown

Immediate Effect of Johnstone's Pressure Splint Added to Stretching on the Spasticity in Cerebrovascular Disease.

Spasticity as Sequela of Stroke
University of Erlangen-Nürnberg
Fa. Reck MOTOmed

Completed

Internet-based MOTOmed Exercise to Reduce Spasticity and Improve Physical Function in Persons With Multiple Sclerosis

Multiple Sclerosis
Jazz Pharmaceuticals

Withdrawn

Phase 3, 28-week, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of Nabiximols as an add-on Therapy in Subjects With Spasticity Due to Multiple Sclerosis.

Multiple Sclerosis | Spasticity
Hacettepe University

Completed

Progressive Functional Strength Training in Unilateral Spastic Cerebral Palsy

Spastic Hemiplegic Cerebral Palsy

Turkey
Virginia Commonwealth University

Terminated

Energy Costs of Spasticity in Spinal Cord Injury: A Pilot Investigation

Spasticity | Basal Energy Expenditure

United States
University of Tokushima
Ministry of Health, Labour and Welfare, Japan

Unknown

Study of a New Generation Botulinum Toxin A2NTX to Treat Spasticity After Stroke (A2NTX)

Lower Limb Spasticity After Stroke

Japan
Eunice Kennedy Shriver National Institute of Child...
Shriners Hospitals for Children; University of Delaware

Unknown

Strength Training Using Neuromuscular Electrical Stimulation For Children With Cerebral Palsy

Spastic Diplegic Cerebral Palsy

United States
Teva GTC

Terminated

One Year Extension Study To Protocol C2/5/TZ:MS-05

Multiple Sclerosis | Spasticity

Israel
Avigen

Terminated

Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Associated With Multiple Sclerosis

Muscle Spasticity

Czech Republic, Ukraine, Germany, Russian Federation, Serbia
University of Hail

Completed

Photo Biostimulation and Spasticity in Cerebral Palsy

Cerebral Palsy | Cerebral Palsy, Spastic

Saudi Arabia
Jazz Pharmaceuticals

Terminated

Safety and Effectiveness of Nabiximols Oromucosal Spray as Add-on Therapy in Participants With Spasticity Due to Multiple Sclerosis (RELEASE MSS3)

Multiple Sclerosis (MS)

United States, Poland, Czechia, United Kingdom, Romania
Ipsen

Completed

Dysport® Pediatric Lower Limb Spasticity Study

Cerebral Palsy | Children | Muscle Spasticity

United States, France, Turkey, Chile, Mexico, Poland
Medical University of Vienna
Imperial College London; Shirley Ryan AbilityLab

Enrolling by invitation

Nerve Transfers in Post-stroke Spasticity

Spasticity as Sequela of Stroke | Nerve Transfers

Austria
Shepherd Center, Atlanta GA
Foundation Wings For Life

Completed

Spinal Cord Stimulation to Augment Activity Based Therapy

Spinal Cord Injuries | Walking | Spasticity | Human | Transcutaneous Spinal Stimulation

United States
October 6 University

Completed

Halliwick Concept on Motor Functions in Spastic CP

Spastic Cerebral Palsy | Spastic Hemiplegic Cerebral Palsy

Egypt
Marmara University

Unknown

Sit to Stand Movement in Children With Cerebral Palsy

Cerebral Palsy, Spastic | Cerebral Palsy, Spastic, Diplegic

Turkey
Universidad Autónoma de Manizales, Colombia

Completed

Effect of Joint Mobilization on Alpha Motoneuron Reflex Excitability (JM-HRreflex)

Stroke | Craniocerebral Trauma | Muscle Spasticity | Spinal Cord Injury

Colombia
National Institute of Neurological Disorders and...

Completed

Eye-Hand Coordination in Children With Spastic Diplegia

Diplegia, Spastic

United States
Universidad Nacional Autonoma de Mexico
National Institute of Pediatrics, Mexico

Recruiting

Changes in Motor and Cognitive Function on Unilateral Spastic Cerebral Palsy, Associated With Videogame Therapy

Cerebral Palsy, Spastic | Hemiplegia, Spastic

Mexico
Ipsen

Recruiting

Effectiveness and Safety of SMART [Spastic Muscle Palpation by Anatomic Landscape for BoNT-A (Botulinumtoxin-A) Injection to Reduce Muscle Tone] BoNT-A Therapy With Dysport® in Patients With Post-stroke Chronic Upper Limb Spasticity (ULS) in Real-life Setting.

Post-Stroke Chronic Upper Limb Spasticity

Germany
University Rehabilitation Institute, Republic of...

Recruiting

Goal Attainment Scaling in Upper Limb Spasticity Treatment (GASBTX)

Ischemic Stroke | Hemorrhagic Stroke

Slovenia
McGill University

Not yet recruiting

Error Augmentation Motor Learning Training Approach in Stroke Patients

Muscle Spasticity | Upper Extremity Paresis | Stroke Rehabilitation | Cerebrovascular Stroke

Canada
National Yang Ming University

Completed

Effects of Neurodynamics on Lower Extremity Spasticity - a Study in Chronic Stroke

Stroke | Chronic Stroke | Spasticity Post Stroke

Taiwan
Ipsen

Completed

Dysport® Pediatric Lower Limb Spasticity Follow-on Study

Cerebral Palsy | Children | Muscle Spasticity

United States, France, Turkey, Chile, Mexico, Poland
Ipsen

Completed

A Study to Assess Treatment Outcomes of abobotulinumtoxinA and onabotulinumtoxinA Treatments in Real Life Practice in Toxin-naïve Adult Patients With Limb Spasticity.

Spasticity Related to Any Cause Except Cerebral Palsy

United Kingdom
Hacettepe University

Completed

The Effect of Cervical Mobilization on Balance and Spasticity in Multiple Sclerosis Individuals

Multiple Sclerosis | Balance; Distorted

Turkey
University of Alberta

Completed

Early Intensive Exercise to Improve Walking in Children With Spastic Diplegia

Spastic Diplegia

Canada
Asir John Samuel

Unknown

Strength Training in Children With Spastic Diplegic and Hemiplegic Cerebral Palsy Receiving Botulinum Toxin

Hemiplegic Cerebral Palsy | Spastic Diplegic Cerebral Palsy
Oslo University Hospital
Sophies Minde; NITO, Norwegian engineering and technology organiziation

Unknown

Changes in Muscle Activity of Children With Spastic Unilat Cerebral Palsy Using 2 Types of Ankle-foot Orthoses to Walk

Hemiplegic Cerebral Palsy | Cerebral Palsy, Spastic

Norway
Arab American University (Palestine)

Not yet recruiting

Anti-Spastic Splint With Focal Muscle Vibration for Stroke Hand Spasticity

Spasticity as Sequela of Stroke

Palestinian Territory, occupied
Technical University of Munich
German Federal Ministry of Education and Research

Recruiting

Priming Effects of Ultra-high Frequency Quattro Pulse Transcranial Brain Stimulation Prior to Hand Motor Function Training in Children With Unilateral Spastic Cerebral Palsy (TRAINCP)

Cerebral Palsy, Spastic | Transcranial Magnetic Stimulation, Repetitive

Germany
Heng-Yi, Shen

Not yet recruiting

H-reflex Measurement in Hemiplegic Stroke Patients

Stroke | Hemiplegia | Spasticity as Sequela of Stroke
Riphah International University

Completed

Incentive Spirometer as a Visual Feedback in Children With Spastic Cerebral Palsy

Cerebral Palsy, Spastic

Pakistan
Riphah International University

Completed

Whole-body Vibration in Spastic Hemiplegic Cerebral Palsy

Cerebral Palsy, Spastic

Pakistan
University of Illinois at Urbana-Champaign
University of Illinois College of Medicine at Peoria; OSF Healthcare System

Unknown

Movement Characterization in Spastic/Dystonic Cerebral Palsy Using Haptic Feedback in Virtual Reality

Cerebral Palsy, Spastic | Cerebral Palsy, Mixed

United States
Merz Pharmaceuticals GmbH

Completed

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Arm After a Stroke (PURE)

Post-stroke Spasticity of the Upper Limb

Poland, United States, Czech Republic, Germany, Hungary, India, Russian Federation
Merz Pharmaceuticals GmbH

Completed

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Leg After a Stroke (PLUS)

Post-stroke Spasticity of the Lower Limb

Germany, Poland, Spain, United States, Czech Republic, Russian Federation, Canada, France, Italy
University Health Network, Toronto

Unknown

POEM for Spastic Esophageal Disorders

Esophageal Achalasia

Canada

Clinical Trials on Muscle Hypotonia

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